Experimental and Clinical Endocrinology and Diabetes 
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Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1624-3593 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 31, 2022 Category: Endocrinology Authors: Sch ütt, Katharina Forst, Thomas Birkenfeld, Andreas L. Zirlik, Andreas M üller-Wieland, Dirk Marx, Nikolaus Tags: German Diabetes Associaton: Clinical Practice Guidelines Source Type: research
Position Paper on Lipid Therapy in Patients with Diabetes
Mellitus
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1624-3572 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 31, 2022 Category: Endocrinology Authors: Parhofer, Klaus G. Birkenfeld, Andreas L. Krone, Wilhelm Lehrke, Michael Marx, Nikolaus Merkel, Martin Sch ütt, Katharina S. Zirlik, Andreas M üller-Wieland, Dirk Tags: German Diabetes Associaton: Clinical Practice Guidelines Source Type: research
Glucose Measurement and Control in Patients with Type 1 or Type 2
Diabetes
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1624-3282 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 31, 2022 Category: Endocrinology Authors: Schl üter, Sandra Deiss, Dorothee Gehr, Bernhard Lange, Karin von Sengbusch, Simone Thomas, Andreas Ziegler, Ralph Freckmann, Guido Tags: German Diabetes Association: Clinical Practice Guidelines Source Type: research
Adjustment of Anti-Hyperglycaemic Agents During Bowel Preparation for
Colonoscopy in Patients with Diabetes
Conclusions While discontinuation of oral AHG and short-acting insulin
during bowel preparation for colonoscopy is generally accepted, recommendations
on the adaptation of basal insulin follow different approaches. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 31, 2022 Category: Endocrinology Authors: M üssig, Karsten Adamek, Henning E. Tags: Article Source Type: research
Family Structure is Associated with Mental Health and Attention
Deficit (Hyperactivity) Disorders in Adolescents with Type 1
Diabetes
Conclusions Our results indicate higher odds of mental health problems and
AD(H)D in adolescents with type 1 diabetes who do not live with both parents;
this finding was most pronounced in individuals living with one parent and
his/her partner vs. both parents. Longitudinal studies are needed to
verify our results and elucidate the underlying mechanisms. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 31, 2022 Category: Endocrinology Authors: Baechle, Christina Stahl-Pehe, Anna Castillo, Katty Holl, Reinhard W. Rosenbauer, Joachim Tags: Article Source Type: research
New Paradigms for Familiar Diseases: Lessons Learned on Circulatory
Bacterial Signatures in Cardiometabolic Diseases
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1756-4509Despite the strongly accumulating evidence for microbial signatures in metabolic
tissues, including the blood, suggesting a novel paradigm for metabolic disease
development, the notion of a core blood bacterial signature in health and
disease remains a contentious concept. Recent studies clearly demonstrate that
under a strict contamination-free environment, methods such as 16 S rRNA
gene sequencing, fluorescence in-situ hybridization, transmission electron
microscopy, and several more, allied with advanced bi...
Source: Experimental and Clinical Endocrinology and Diabetes - March 23, 2022 Category: Endocrinology Authors: Chakaroun, Rima Massier, Lucas Musat, Niculina Kovacs, Peter Tags: Review Source Type: research
Maprotiline Ameliorates High Glucose-Induced Dysfunction in Renal
Glomerular Endothelial Cells
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1713-7719Maprotiline is an antidepressant that has been found to cause hypoglycemia.
However, the effect of maprotiline on diabetic nephropathy (DN) has not been
investigated. Here, we explored the effect of maprotiline on human renal
glomerular endothelial cells (HRGECs) in response to high glucose (HG)
stimulation. We found that maprotiline attenuated HG-induced oxidative stress in
HRGECs with decreased reactive oxygen species production and increased
superoxide dismutase activity. Maprotiline repressed the HG-induced ...
Source: Experimental and Clinical Endocrinology and Diabetes - March 23, 2022 Category: Endocrinology Authors: Zhou, Zhihong Liu, Shangjun Tags: Article Source Type: research
Statin Therapy Among Bariatric Patients: The Impact on Metabolic
Outcomes and Diabetes Status
Conclusion Bariatric surgery seems to lead to diabetes remission more
frequently in patients not treated with statins. A larger reduction was observed
in fasting glucose and HbA1c among statin-treated patients. Statin did not
contribute to an increased proportion of new-onset diabetes after surgery. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 23, 2022 Category: Endocrinology Authors: Mendon ça, Fernando M Silva, Maria M Borges-Canha, Marta Neves, Jo ão S Costa, Cl áudia Cabral, Pedro M. Guerreiro, Vanessa Louren ço, Rita Meira, Patr ícia Ferreira, Maria J Salazar, Daniela Pedro, Jorge Varela, Ana Souto, Selma Lau, Eva Freitas, Pa Tags: Article Source Type: research
What is the Role of Thyroid Hormone Receptor Alpha 2
(TR α2) in Human Physiology?
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1716-7980Thyroid hormone receptors are nuclear receptors that function as transcription
factors and are regulated by thyroid hormones. To date, a number of variants and
isoforms are known. This review focuses on the thyroid hormone receptor
α (TRα), in particular TRα2, an isoform that arises from
alternative splicing of the THRA mRNA transcript. Unlike the TRα1
isoform, which can bind T3, the TRα2 isoform lacks a ligand-binding
domain but still binds to DNA thereby antagonizing the transcriptional activity
...
Source: Experimental and Clinical Endocrinology and Diabetes - March 7, 2022 Category: Endocrinology Authors: Paisdzior, Sarah Schuelke, Markus Krude, Heiko Tags: Article Source Type: research
Leveraging Potential of Nanotherapeutics in Management of Diabetic
Foot Ulcer
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1749-4909Diabetic foot ulcers (DFUs) are the most common complications associated with
diabetes mellitus. DFUs are displayed as open sores or wounds located on the
bottom of the foot as a secondary complication of diabetes mellitus (DM). DFUs
are associated with significant morbidity and mortality and can subsequently
lead to hospitalization and lower limb amputation if not recognized and treated
on time. An immense challenge to conventional treatments is caused by the
chronic nature of diabetic foot syndrome and it has ...
Source: Experimental and Clinical Endocrinology and Diabetes - March 3, 2022 Category: Endocrinology Authors: Pandey, Supriya Shaif, Mohammad Ansari, Tarique M Shamim, Arshiya Kushwaha, Poonam Tags: Mini-Review Source Type: research
The ISAQ Score Does Not Predict Adrenal Crisis in Patients with
Primary Adrenal Insufficiency
Conclusions The ISAQ score does not identify patients prone to ACs. The
COVID-19 pandemic and consecutive lockdown measures significantly diminished the
frequency of infectious events and ACs. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 3, 2022 Category: Endocrinology Authors: Quinkler, Marcus Kienitz, Tina Tags: Article Source Type: research
Measurement of Gastric Emptying Using a 13C-octanoic Acid
Breath Test with Wagner-Nelson Analysis and Scintigraphy in Type 2
Diabetes
Conclusion In type 2 diabetes, gastric emptying of a mashed potato meal
measured using a 13C-octanoic acid breath test analysed with
Wagner-Nelson Kel=0.60 closely reflects measurements obtained
with scintigraphy, whereas, in absolute terms, the conventional breath test
analysis does not. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 1, 2022 Category: Endocrinology Authors: Trahair, Laurence G Nauck, Michael A Wu, Tongzhi Stevens, Julie E Buttfield, Madeline D Hatzinikolas, Seva Pham, Hung Meier, Juris J Rayner, Christopher K Horowitz, Michael Jones, Karen L Tags: Article Source Type: research
Measurement of gastric emptying using a 13C-octanoic acid breath test with Wagner-Nelson analysis and scintigraphy in type 2 diabetes.
Conclusion: In type 2 diabetes, gastric emptying of a mashed potato meal measured using a <sup>13</sup>C-octanoic acid breath test analysed with Wagner-Nelson Kel=0.60 closely reflects measurements obtained with scintigraphy, whereas, in absolute terms, the conventional breath test analysis does not. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 1, 2022 Category: Endocrinology Authors: Jones, Karen L Trahair, Laurence G Nauck, Michael A. Wu, Tongzhi Stevens, Julie E Buttfield, Madeline D Hatzinikolas, Seva Pham, Hung Meier, Juris J. Rayner, Christopher K. Horowitz, Michael Tags: Article Source Type: research
Obesity – A Matter of Motivation?
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1749-4852Excessive food intake and reduced physical activity have long been established as
primary causes of obesity. However, the underlying mechanisms causing this
unhealthy behavior characterized by heightened motivation for food but not for
physical effort are unclear. Despite the common unjustified stigmatization that
obesity is a result of laziness and lack of discipline, it is becoming
increasingly clear that high-fat diet feeding and obesity cause alterations in
brain circuits that are critical for the control of...
Source: Experimental and Clinical Endocrinology and Diabetes - February 18, 2022 Category: Endocrinology Authors: Hanssen, Ruth Thanarajah, Sharmili E Tittgemeyer, Marc Br üning, Jens C. Tags: Mini-Review Source Type: research
COVID-19 Lockdown Periods in 2020: Good Maintenance of Metabolic
Control in Adults with Type 1 and Type 2 Diabetes
We presented these outcomes as adjusted medians with
95% confidence intervals. Rates were compared using negative-binomial
models, dichotomous outcomes were compared using logistic models. Models were
additionally adjusted for age and diabetes duration. These outcomes were
presented as least-square means with 95% confidence intervals, p-values
of<.05 were considered significant.In participants with T1DM, CGI (combined glucose indicator) increased only by
0.11–0.12% in all time periods of 2020 compared to 2019 (all
p<0.001) while BMI decreased sli...
Source: Experimental and Clinical Endocrinology and Diabetes - February 18, 2022 Category: Endocrinology Authors: Hartmann, B Tittel, S R Femerling, M Pfeifer, M. Meyh öfer, S. Lange, K Milek, S Stemler, L Best, F Holl, R W Tags: Article Source Type: research
