Revived Attention for Adult Craniopharyngioma
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1217-7282Craniopharyngioma as a rare tumor originating from cells of rathke’s pouch and representing 2–5% of all intracranial tumors is a rare and generally benign neoplasm of the central nervous system with two incidence peaks one in childhood and one after 40 years of age. Data on adult patients is scarce compared to childhood onset tumors, however the burden of disease caused by the tumors and related treatment options is significant. Clinical symptoms range from headaches, visual disability, cranial nerve affecti...
Source: Experimental and Clinical Endocrinology and Diabetes - August 3, 2020 Category: Endocrinology Authors: Mende, Klaus Christian Pantel, Tobias Fabian Flitsch, J örg Tags: Review Source Type: research

Knock-Down of Long Non-Coding RNA ANRIL Suppresses Mouse Mesangial Cell Proliferation, Fibrosis, Inflammation via Regulating Wnt/ β-Catenin and MEK/ERK Pathways in Diabetic Nephropathy
Conclusions Lnc-ANRIL knock-down suppresses mouse mesangial cell proliferation, fibrosis, inflammation, Wnt/β-catenin and MEK/ERK pathways in DN. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - July 28, 2020 Category: Endocrinology Authors: Fang, Xun Hu, Jun Zhou, Hongyan Tags: Article Source Type: research

Prevalence of Signs and Symptoms of Pseudotumor Cerebri Syndrome Before and After Transsphenoidal Surgery for Cushing ’s Disease – A Prospective Consecutive Case Series
Conclusion Our results suggest a very low frequency of signs and symptoms of PTCS after surgical treatment for CD in adults. This estimate is in line with previous outcomes from retrospective pediatric CD series. Further large-scale studies are needed to determine the actual prevalence of this condition following biochemical remission of CD. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - July 27, 2020 Category: Endocrinology Authors: Huckhagel, Torge Flitsch, J örg Rotermund, Roman Knospe, Volker Tags: Article Source Type: research

Quality of Life and Treatment Satisfaction in Participants with Maturity-Onset Diabetes of the Young: A Comparison to Other Major Forms of Diabetes
Conclusions QoL was affected in both GCK-MODY and HNF-MODY subjects. Apprehension of genetic diagnosis was not single-valued in MODY respondents. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - July 27, 2020 Category: Endocrinology Authors: Dusatkova, Petra Pavlikova, Marketa Spirkova, Alena Elblova, Lenka Zdarska, Denisa Janickova Rozenkova, Klara Hron, Jakub Sumnik, Zdenek Cinek, Ondrej Lebl, Jan Pruhova, Stepanka Tags: Article Source Type: research

Mortality of Patients with Cushing ’s Disease
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1197-6380Cushing’s disease is a rare condition of cortisol excess attributed to a pituitary adenoma with an annual incidence of 1.2–2.4 cases per million population. It is associated with several co-morbidities leading to increased mortality predominantly due to cardiovascular disease. Despite the advances in its diagnosis and management, survival can be compromised even after apparent successful treatment. Minimizing the duration and extent of exposure to hypercortisolaemia by early diagnosis and rapid, effective th...
Source: Experimental and Clinical Endocrinology and Diabetes - July 8, 2020 Category: Endocrinology Authors: Ntali, Georgia Hakami, Osamah Wattegama, Milanka Ahmed, Shahzada Karavitaki, Niki Tags: Review Source Type: research