Exceptional Response of Nelson ’s Syndrome to Pasireotide LAR in the Long-Term Follow-up of 9 Years
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1158-9214 [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - November 12, 2020 Category: Endocrinology Authors: Fill, Sandra M. Popp, Kathrin H. Stalla, G ünter K. Athanasoulia-Kaspar, Anastasia P. Tags: Letter to the Editor Source Type: research

Effects of a Combined Endurance/Strength Training Program on Circulating Irisin Levels in Overweight/Obese Men and Women with Type 2 Diabetes Mellitus
This study shows no training-induced (sex-specific) changes in circulating irisin levels in T2DM patients. Large-scale studies using other forms of training are needed to fully clarify whether basal irisin levels can be changed in T2DM men and/or women to counteract T2DM. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - November 11, 2020 Category: Endocrinology Authors: Brinkmann, Christian Weh-Gray, Olivier Bloch, Wilhelm Brixius, Klara Predel, Hans-Georg Kreutz, Thorsten Tags: Article Source Type: research

COVID-19 and Cardiovascular Comorbidities
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1269-1405The emergence of a new coronavirus - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - has resulted in a global pandemic. The associated coronavirus disease 2019 (COVID-19) has resulted in a high number of death worldwide. Observational studies and case reports have provided insights that older age and the presence of chronic diseases is frequently associated with a higher COVID-19 severity. These individuals also seem to have a higher risk of mortality due to COVID-19. In this review we provide insights into the impact chronic diseases associated with the c...
Source: Experimental and Clinical Endocrinology and Diabetes - November 6, 2020 Category: Endocrinology Authors: M üller-Wieland, Dirk Marx, Nikolaus Dreher, Michael Fritzen, Katharina Schnell, Oliver Tags: Review Source Type: research

The Effect of Immunosuppression on Selected Antioxidant Parameters in Patients with Graves ’ Disease with Active Thyroid-Associated Orbitopathy
Conclusion Results of our study confirmed that oxidative stress is one of the factors involved in the pathogenesis of thyroid-associated orbitopathy and the methyloprednisolone treatment is effective in reducing both clinical symptoms and oxidative stress in patients with this disease. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - November 6, 2020 Category: Endocrinology Authors: Londzin-Olesik, Magdalena Kos-Kudla, Beata Karpe, Jacek Nowak, Aleksandra Nowak, Mariusz Tags: Article Source Type: research

Trabecular Bone is Increased in a Rat Model of Polycystic Ovary Syndrome
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1284-5491Polycystic ovary syndrome (PCOS) in an intricate disorder characterized by reproductive and metabolic abnormalities that may affect bone quality and strength along with the lifespan. The present study analysed the impact of postnatal androgenization (of a single dose of testosterone propionate 1.25 mg subcutaneously at day 5 of life) on bone development and markers of bone metabolism in adult female Wistar rats. Compared with healthy controls, the results of measurements of micro-computed tomography (microCT) of the distal femur of androgenized rats indicated an increa...
Source: Experimental and Clinical Endocrinology and Diabetes - October 28, 2020 Category: Endocrinology Authors: Mujica, Lady Katerine Serrano Glanzner, Werner Giehl Prante, Amanda Luiza Rissi, Vitor Braga Correa, Gabrielle Rebeca Everling Premaor, Melissa Orlandin Antoniazzi, Alfredo Quites Gon çalves, Paulo Bayard Dias Comim, Fabio Vasconcellos Tags: Article Source Type: research

Correction: The Effects of Calcium, Vitamins D and K co-Supplementation on Markers of Insulin Metabolism and Lipid Profiles in Vitamin D-Deficient Women with Polycystic Ovary Syndrome
Exp Clin Endocrinol Diabetes 2020; 128: 771-771 DOI: 10.1055/a-1270-8600 [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - October 28, 2020 Category: Endocrinology Authors: Karamali, Maryam Ashrafi, Mahnaz Razavi, Maryamalsadat Jamilian, Mehri Akbari, Maryam Asemi, Zatollah Tags: Erratum Source Type: research

Effectiveness of Cabergoline Treatment in Patients with Acromegaly Uncontrolled with SSAs: Experience of a Single Tertiary Center
Conclusion Cabergoline can be added to the treatment of acromegalic patients uncontrolled with SSAs due to its ease of use and low economic cost, especially in patients with acromegaly who have small adenomas and no fibrous bodies. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - October 23, 2020 Category: Endocrinology Authors: Sahin, Serdar Fidan, Mehmet Cem Korkmaz, Ozge Polat Durcan, Emre Ozkaya, Hande Mefkure Kadioglu, Pinar Tags: Article Source Type: research

Antecubital Vein Cannula Position Impacts Assessment of Forearm Glucose Uptake During an Oral Glucose Challenge in Healthy Volunteers
This study aimed to determine the impact of venous cannula position on calculated forearm glucose uptake following an oral glucose challenge in resting and post-exercise states. Materials and Methods In 9 young, lean, males, the impact of sampling blood from two antecubital vein positions; the perforating vein (‘perforating’ visit) and, at the bifurcation of superficial and perforating veins (‘bifurcation’ visit), was assessed. Brachial artery blood flow and arterialised-venous and venous blood glucose concentrations were measured in 3 physiological states; resting-fasted, resting-fed, and fed following intermitten...
Source: Experimental and Clinical Endocrinology and Diabetes - October 23, 2020 Category: Endocrinology Authors: B étry, Cécile Nixon, Aline V. Greenhaff, Paul L. Simpson, Elizabeth J. Tags: Article Source Type: research

G-protein Coupled Estrogen Receptor Expression in Growth Hormone Secreting and Non-Functioning Adenomas
Conclusions GPER1 is expressed at both gene and protein level in a substantial portion of GH-secreting adenomas and NFAs. The finding of a positive correlation between GPER1 and ERα, ERβ, PTTG, and FGF2 gene expression and aromatase and GPER1 protein expression suggests GPER1 along with aromatase and classical ERs might mediate the effects of estrogen through upregulation of PTTG and FGF2. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - October 22, 2020 Category: Endocrinology Authors: Ozkaya, Hande Mefkure Sayitoglu, Muge Comunoglu, Nil Sun, Eda Keskin, Fatma Ela Ozata, Duygu Hocaoglu, Rabia Hacer Khodzaev, Khusan Firtina, Sinem Tanriover, Necmettin Gazioglu, Nurperi Oz, Buge Kadioglu, Pinar Tags: Article Source Type: research

How Reliable are Commercially Available Glypican4 ELISA Kits?
Conclusions Extensive evaluation of the performance of two commercially available ELISA kits led to the conclusion that none of them is applicable for the measurement of glypican4 in human blood samples. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - October 16, 2020 Category: Endocrinology Authors: Buhl, Joseph P. Garten, Antje Kratzsch, J ürgen Kiess, Wieland Penke, Melanie Tags: Article Source Type: research

Let7b-5p is Upregulated in the Serum of Emirati Patients with Type 2 Diabetes and Regulates Insulin Secretion in INS-1 Cells
In conclusion, an appropriate level of let7b-5p is essential to maintain β-cell function and may be regarded as a biomarker for T2DM. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - October 9, 2020 Category: Endocrinology Authors: Aljaibeji, Hayat Elemam, Noha Mousaad Mohammed, Abdul Khader Hasswan, Hind Thahyabat, Mahammad Al Alkhayyal, Noura Sulaiman, Nabil Taneera, Jalal Tags: Article Source Type: research

Football – Novel Approaches to Tackle Diabetes
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-1262-6352Balanced diet and regular physical activity are of key importance to the prevention of the development and progression of non-communicable diseases. In 2050, 50% of the European population is expected to be obese. Cardiovascular diseases, diabetes mellitus, cancer, as well as joint impairments, will further increase. Therefore, programmes are critical to the improvement of the population’s health status in the long run. New ways have to be found that allow addressing more people than with the current approaches. Football has a great potential to attract people at risk ...
Source: Experimental and Clinical Endocrinology and Diabetes - October 7, 2020 Category: Endocrinology Authors: M üssig, Karsten Adamek, Henning E. Tags: Mini-Review Source Type: research

Elevated Circulating LINC-P21 Serves as a Diagnostic Biomarker of Type 2 Diabetes Mellitus and Regulates Pancreatic β-cell Function by Sponging miR-766-3p to Upregulate NR3C2
Conclusion All the data demonstrated that serum elevated LINC-P21 and decreased miR-766-3p serve as candidate diagnostic biomarkers in T2DM patients. LINC-P21 acts as a potential regulator in insulin secretion and proliferation of pancreatic β-cells through targeting miR-766-3p to upregulate NR3C2. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - October 1, 2020 Category: Endocrinology Authors: Cao, Zhibin Yao, Fuwang Lang, Yuqin Feng, Xueqiang Tags: Article Source Type: research

Neuropsychological Functioning in Patients with Cushing ’s Disease and Cushing’s Syndrome
Conclusions Memory is the most extensively investigated domain in CS/CD patients and impairment is most prominent in active disease. Patients should be counseled that neuropsychological function will improve with normalization of hypercortisolism and over time. More studies with more stringent methodological criteria, larger patient samples and controlling for confounders are required to enhance our understanding of neuropsychological function in patients with CS/CD. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental a...
Source: Experimental and Clinical Endocrinology and Diabetes - September 28, 2020 Category: Endocrinology Authors: Siegel, Sonja Kirstein, Cedric Fabian Grzywotz, Agnieszka H ütter, Bernd Otto Wrede, Karsten Henning Kuhna, Victoria Kreitschmann-Andermahr, Ilonka Tags: Review Source Type: research

Glucagon Like Peptide-1 Receptor Agonists Alters Pancreatic and Hepatic Histology and Regulation of Endoplasmic Reticulum Stress in High-fat Diet Mouse Model
Conclusion Liraglutide reduces the severity of NAFPD and NAFLD may through regulating the ER stress pathway and downstream apoptosis signaling. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - September 21, 2020 Category: Endocrinology Authors: Fang, Taiyong Huang, Siying Chen, Yongpeng Chen, Zongchi Chen, Jiangmu Hu, Weitao Tags: Article Source Type: research