Noninvasive continuous arterial pressure monitoring with Clearsight during awake carotid endarterectomy: A prospective observational study
CONCLUSION During CEA performed under regional anaesthesia, CNBP offers a less invasive approach for BP monitoring. We found acceptable agreement for MAP defined by an ATI of 0.88 and an excellent 95% global interchangeability rate. A suboptimal bias of 7 mmHg was found with CNBP for MAP. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Monitoring Source Type: research

Monitoring haemodynamic response to fluid-challenge in ICU: comparison of pressure recording analytical method and oesophageal Doppler: A prospective observational study
CONCLUSION When compared with ODM, PRAM has insufficient performance to track ΔCO induced by fluid challenge in ICU patients. Baseline bias is an independent predictor of trending bias. TRIAL REGISTRATION IRB 00010254-2016-033. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Monitoring Source Type: research

Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: An observational study
This study aimed to assess the acute peri-operative changes in endothelial function after minor elective abdominal surgery. DESIGN A prospective, observational, single-centre study. SETTING A university hospital from February 2016 to January 2017. PATIENTS Sixty patients undergoing elective minor abdominal surgery. MAIN OUTCOME MEASURES The change in endothelial function, expressed as the reactive hyperaemia index (RHI), was assessed by non-invasive digital pulse tonometry. RHI, biomarkers of nitric oxide bioavailability and oxidative stress were assessed prior to and 4 h after surgery. RESULTS RHI decreas...
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Orthostatic intolerance following hip arthroplasty: incidence, risk factors and effect on length of stay: A prospective cohort study
CONCLUSION Orthostatic intolerance is common after total hip arthroplasty. Optimising pain control prior to mobilisation and limiting gabapentin use may modify the risk of developing postoperative orthostatic intolerance. Although personalised recovery pathways appear attractive, at present, the ability to predict at-risk individuals is still limited. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Relevance of peripheral cholinesterase activity on postoperative delirium in adult surgical patients (CESARO): A prospective observational cohort study
CONCLUSION Peri-operative peripheral cholinesterase activities may be related to the development of POD, but the clinical implications remain unclear. Further studies, in homogeneous patient groups with a strict protocol for measurement time points, are needed to investigate the relationship between cholinesterase activities and POD. TRIAL REGISTRATION www.clinicaltrials.gov. Identifier NCT01964274. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Intra-operative tachycardia is not associated with a composite of myocardial injury and mortality after noncardiac surgery: A retrospective cohort analysis
CONCLUSION There was no apparent association between various measures of tachycardia and a composite of MINS and death, a result that contradicts previously reported associations between other measures of intra-operative tachycardia and MINS/mortality. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Development of a prediction model for postoperative pneumonia: A multicentre prospective observational study
BACKGROUND Postoperative pneumonia is associated with increased morbidity, mortality and costs. Prediction models of pneumonia that are currently available are based on retrospectively collected data and administrative coding systems. OBJECTIVE To identify independent variables associated with the occurrence of postoperative pneumonia. DESIGN A prospective observational study of a multicentre cohort (Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe database). SETTING Sixty-three hospitals in Europe. PATIENTS Patients undergoing surgery under general and/or regional an...
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Intra-operative heart rate and postoperative outcomes – rowing against the tide?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Invited commentaries Source Type: research

Postoperative pneumonia: Can this important complication be predicted and anticipated?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Invited commentaries Source Type: research

Thank you to our Peer Reviewers for 2018
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Announcement Source Type: research

Retraction: Visual evaluation of train-of-four and double burst stimulation, fade at various currents, using a rubber band. Saitoh Y, Nakazawa K, Makita K, et al.
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Retraction Source Type: research

Reply to: cerebral oximetry monitoring. To guide physiology, avert catastrophe or both?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Cerebral oximetry monitoring. To guide physiology, avert catastrophe or both?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: prediction of bilateral cerebral oxygen desaturation from a single sensor in adult cardiac surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Prediction of bilateral cerebral oxygen desaturation from a single sensor in adult cardiac surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: fluid therapy for critical haemorrhage during elective noncardiac surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Fluid therapy for critical haemorrhage during elective noncardiac surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

The effect of pectoral block type II on persistent pain: Follow up of a randomised trial and hypotheses for further analyses
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Assessing the effect of dexmedetomidine in patients with pre-eclampsia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Continuous haemodynamic effects of left tilting and supine positions during Caesarean section under spinal anaesthesia with a noninvasive cardiac output monitor system
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Ketamine-induced anaphylactic shock during elective parotidectomy: A case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia care team improves outcomes in surgical patients compared with solo anaesthesiologist: An observational study
CONCLUSION Anaesthesia given by teams of anaesthesiologists and anaesthesia nurses is associated with decreased 30-day postoperative mortality and shorter length of stay when compared with solo anaesthesiologists. Even without any demonstration of causality, this emphasises the benefits of the anaesthesia care team model. TRIAL REGISTRATION CCB 325201730849. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Teamwork Source Type: research

Incidence of peri-operative paediatric cardiac arrest and the influence of a specialised paediatric anaesthesia team: Retrospective cohort study
CONCLUSION In this study on incidences of peri-operative paediatric cardiac arrest from a European tertiary care university hospital, implementation of a specialised paediatric anaesthesia team and training programme was associated with lower incidences of peri-operative paediatric cardiac arrest and a reduced probability of anaesthesia-attributable cardiac arrest. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Teamwork Source Type: research

Efficacy of axillary versus infraclavicular brachial plexus block in preventing tourniquet pain: A randomised trial
BACKGROUND Axillary and infraclavicular brachial plexus blocks are commonly used for upper limb surgery. Clinicians require information on the relative benefits of each to make a rational selection for specific patients and procedures. OBJECTIVES The main objective of the study was to compare axillary and infraclavicular brachial plexus block in terms of the incidence and severity of tourniquet pain. DESIGN Single blinded, randomised trial. SETTING University affiliated hospital, level-1 trauma centre. PATIENTS Age more than 18 years, ASAI-III patients undergoing orthopaedic surgery distal to the elbow, with ...
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Loco-regional anaesthesia Source Type: research

Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind, randomised study
CONCLUSION Bilateral suprazygomatic maxillary nerve block is an effective and safe alternative to the traditional peripheral nerve blocks for cleft lip and cleft palate surgery, in a mixed paediatric and adult population. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Loco-regional anaesthesia Source Type: research

Short- and long-term impact of remifentanil on thermal detection and pain thresholds after cardiac surgery: A randomised controlled trial
CONCLUSION Earlier reports of increased pain sensitivity 1 year after the use of remifentanil could not be confirmed in this randomised study using Quantitative Sensory Testing. This indicates that remifentanil plays a minor role in the development of chronic thoracic pain. Still, the relatively high incidence of chronic thoracic pain and its accompanying impact on quality of life remain challenging problems. TRIAL REGISTRATION The study was registered at EudraCT (ref: 2013-000201-23) and ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT02031016). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Shared decision-making for postoperative analgesia: A semistructured qualitative study
CONCLUSION The results of this study suggest that both patients and professionals did not adhere to some ‘self-evident’ principles of SDM when postoperative analgesia after major thoracic and abdominal surgery was discussed. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Effects of a single subanaesthetic dose of ketamine on pain and mood after laparoscopic bariatric surgery: A randomised double-blind placebo controlled study
BACKGROUND When administered as a continuous infusion, ketamine is known to be a potent analgesic and general anaesthetic. Recent studies suggest that a single low-dose administration of ketamine can provide a long-lasting effect on mood, but its effects when given in the postoperative period have not been studied. OBJECTIVE We hypothesised that a single low-dose administration of ketamine after bariatric surgery can improve pain and mood scores in the immediate postoperative period. DESIGN We performed a randomised, double-blind, placebo-controlled study to compare a single subanaesthetic dose of ketamine (0.4 m...
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Low-dose ketamine infusion reduces postoperative hydromorphone requirements in opioid-tolerant patients following spinal fusion: A randomised controlled trial
BACKGROUND The current opioid epidemic highlights the urgent need for effective adjuvant therapies to complement postoperative opioid analgesia. Intra-operative ketamine infusion has been shown to reduce postoperative opioid consumption and improve pain control in opioid-tolerant patients after spinal fusion surgery. Its efficacy for opioid-naïve patients, however, remains controversial. OBJECTIVE We hypothesised that low-dose ketamine infusion after major spinal surgery reduces opioid requirements in opioid-tolerant patients, but not in opioid-naïve patients. DESIGN Randomised placebo-controlled study. ...
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Uterine tilt for caesarean section
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Invited commentary Source Type: research

Targeting the affective component of pain with ketamine: A tool to improve the postoperative experience?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Invited commentary Source Type: research

Ketamine stakes in 2018: Right doses, good choices
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Invited commentary Source Type: research

Paucity of evidence for the effectiveness of prophylactic low-dose oxytocin protocols (
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Reporting of time to rescue analgesia: Would it have made a difference in results?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Life-threatening ketoacidosis in a lactating woman
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Green blood plasma from a patient with breast cancer after sentinel lymph node biopsy
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Intra-osseous-access-associated lower limb compartment syndrome in a critically injured paediatric patient
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: a child with Koolen-de Vries syndrome
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Correspondence Source Type: research

How current transfusion practices in geriatric patients with hip fracture still differ from current guidelines and the effects on outcome: A retrospective observational study
CONCLUSION Most RBC transfusions occur postoperatively, many still according to liberal transfusion thresholds, in particular shortly before discharge and as part of consecutive transfusions. Transfused patients had longer LOS and more infections than patients not transfused, but there was no difference in mortality, LOS or morbidity between patients transfused according to current guidelines and those where guidelines were deviated from. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Miscalleneous Source Type: research

Incidence of akathisia after postoperative nausea and vomiting prophylaxis with droperidol and ondansetron in outpatient surgery: A multicentre controlled randomised trial
CONCLUSION The use of droperidol or ondansetron for PONV prophylaxis is associated to a low incidence of akathisia (0.8 to 3.4%) after general anaesthesia for ambulatory surgery. TRIAL REGISTRATION Clinicaltrials.gov: NCT01942343. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Miscalleneous Source Type: research

Comparison of the peripheral antinociceptive effect of somatostatin with bupivacaine and morphine in the rodent postoperative pain model
CONCLUSION Guarding behaviour, which likely represents pain-at-rest following surgery, was attenuated by both bupivacaine and SST to comparable extents. This novel peripherally mediated antinociceptive effect of SST needs further evaluation. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Miscalleneous Source Type: research

ICU mortality and variables associated with ICU survival in Poland: A nationwide database study
BACKGROUND Recently published international comparison data across European countries revealed high mortality rates in Polish ICUs. OBJECTIVES Estimation of the rate of ICU mortality and identification of variables associated with ICU survival in Poland. DESIGN Retrospective analyses of a database reporting ICU stays in Poland. SETTINGS AND PATIENTS The study included data from all adult patients admitted to an ICU in Poland from 1 January 2012 to 31 December 2012. MAIN OUTCOME MEASURES ICU mortality and variables associated with ICU survival. RESULTS A total of 48 282 patients were treated in 347 ICUs (...
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Miscalleneous Source Type: research

The degree of adherence to CONSORT reporting guidelines for the abstracts of randomised clinical trials published in anaesthesia journals: A cross-sectional study of reporting adherence in 2010 and 2016
CONCLUSION Abstracts for many anaesthesiology RCTs are incomplete selective summaries of the entire article. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Miscalleneous Source Type: research

Ultrasound assessment of gastric emptying time after a standardised light breakfast in healthy children: A prospective observational study
OBJECTIVES Current guidelines recommend 6 h of fasting for solids before anaesthesia. However, prolonged fasting may lead to discomfort, hunger, thirst, misbehaviour and lipolysis. To prevent this, a more liberal fasting regimen has been empirically implemented in our children's hospital, allowing a shorter fasting time of 4 h for a standardised light breakfast. AIM The aim of this study was to determine the gastric emptying time after a standardised light breakfast in healthy children. DESIGN A prospective observational noninterventional study. METHODS After fasting overnight, the children had a standardise...
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Emergence delirium in children is related to epileptiform discharges during anaesthesia induction: An observational study
CONCLUSION Emergence delirium in children is significantly related to interictal spike events occurring during induction of anaesthesia. CLINICAL TRIAL NCT02481999. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Peri-operative respiratory adverse events in children with upper respiratory tract infections allowed to proceed with anaesthesia: A French national cohort study
CONCLUSION The risk of PRAE in patients anaesthetised in the presence of URTI was similar to previous publications – close to 30%. In the light of our findings, first, current rescheduling indications should be questioned, and second, further medical and organisational strategies should be investigated to reduce PRAE in children with URTI. TRIAL REGISTRATION The study was registered in the European Networks of Centers for Pharmacoepidemiology and Pharmacovigilance (EUPAS16436). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Peri-operative oral caffeine does not prevent postoperative atrial fibrillation after heart valve surgery with cardiopulmonary bypass: A randomised controlled clinical trial
CONCLUSION Oral caffeine does not prevent POAF after heart valve surgery with CPB but increased the incidence of postoperative nausea and vomiting. CLINICAL TRIAL REGISTRATION ClinicalTrials.gov, no.: NCT01999829. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Christmas isue Source Type: research

Near-infrared spectroscopy in vegetables and humans: An observational study
We report NIRS values for some common vegetables and faculty at a world-class medical institution. DESIGN Observational nonblinded study. SETTING Single tertiary care institution and local urban vegetable market. PARTICIPANTS Five yams (Dioscorea cayenensis), five courgettes (Cucurbita pepo) and five butternut squashes (Cucurbita moschata) were studied. Five cardiothoracic surgeons and anaesthesiologists were the control group. INTERVENTIONS None. MAIN OUTCOME MEASURES NIRS value of each species. RESULTS Mean NIRS value for the control group was 71% [95% confidence interval (CI) 68 to 74] and was similar ...
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Christmas isue Source Type: research

Pitfalls of clinical practice guidelines in the era of broken science: Let's raise the standards
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - November 2, 2018 Category: Anesthesiology Tags: Editorial Source Type: research