Short-axis/out-of-plane or long-axis/in-plane ultrasound-guided arterial cannulation in children: A randomised controlled trial
CONCLUSION: Despite the longer imaging time with the LAX approach, there was no significant difference in the total time to successful cannulation between the two techniques. The posterior wall puncture rate was lower in the LAX group than in the SAX group. TRIAL REGISTRATION: Clinicaltrials.gov (identifier: NCT02333786). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Intravascular volume therapy in adults: Guidelines from the Association of the Scientific Medical Societies in Germany
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Volume therapy Source Type: research

The quest for the holy volume therapy
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Invited commentary Source Type: research

The half-life of infusion fluids: An educational review
An understanding of the half-life (T1/2) of infused fluids can help prevent iatrogenic problems such as volume overload and postoperative interstitial oedema. Simulations show that a prolongation of the T1/2 for crystalloid fluid increases the plasma volume and promotes accumulation of fluid in the interstitial fluid space. The T1/2 for crystalloids is usually 20 to 40 min in conscious humans but might extend to 80 min or longer in the presence of preoperative stress, dehydration, blood loss of (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Review Source Type: research

Ethics in practice: is it futile to talk about ‘futility’?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Editorial Source Type: research

Perioperative Medicine for the Junior Clinician
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Book review Source Type: research

Reply to: the use of advanced airway management devices in clinical practice
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The use of advanced airway management devices in clinical practice
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Changes in intracranial pressure and cerebral blood flow during volatile anaesthesia: Fact or fiction?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Incidence of general anaesthesia for caesarean section in parturients from different geographic regions: 7-year retrospective study in a single European university centre
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Bilateral hypoglossal nerve palsy and unilateral recurrent laryngeal nerve palsy following lumbar discectomy: A case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Estimation of the minimum effective volume of 0.5% bupivacaine for ultrasound-guided axillary brachial plexus block
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Black or white coffee before anaesthesia?: A randomised crossover trial
CONCLUSION: The study provides evidence that adding up to 50% full fat milk to coffee leads to no or only a minimal increase of the gastric volume 2 h later. The results support a liberalisation of policy on the addition of milk to hot drinks before planned anaesthesia. TRIAL REGISTRATION: www.Clinicaltrials.gov identifier: NCT02361632. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Intraoperative hypotension is associated with myocardial damage in noncardiac surgery: An observational study
CONCLUSIONS: In a cohort of 300 patients undergoing major elective noncardiac surgery, there was a high incidence of myocardial damage and an association between an intraoperative reduction in SBP more than 50% from baseline lasting more than 5 min and myocardial damage. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

High levels of preoperative and postoperative N terminal B-type natriuretic propeptide influence mortality and cardiovascular complications after noncardiac surgery: A prospective cohort study
CONCLUSION: High levels of preoperative and postoperative NT-proBNP are predictors of cardiovascular complications, including all-cause mortality, during the first 30 days after noncardiac surgery in adults with cardiovascular risk factors. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Preoperative hydration with 0.9% normal saline to prevent acute kidney injury after major elective open abdominal surgery: A randomised controlled trial
CONCLUSION: Intravenous hydration with 0.9% normal saline before major open abdominal surgery was not effective in preventing postoperative AKI. No safety concerns were identified during the trial. TRIAL REGISTRATIONS: Clinical trials.gov: NCT00953940 and EUDRA CT: 2005-004755-35. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Targeting oliguria reversal in perioperative restrictive fluid management does not influence the occurrence of renal dysfunction: A systematic review and meta-analysis
BACKGROUND: Interest in perioperative fluid restriction has increased, but it could lead to hypovolaemia. Urine output is viewed as a surrogate for renal perfusion and is frequently used to guide perioperative fluid therapy. However, the rationale behind targeting oliguria reversal – achieving and maintaining urine output above a previously defined threshold by additional fluid boluses – is often questioned. OBJECTIVE: We assessed whether restrictive fluid management had an effect on oliguria, acute renal failure (ARF) and fluid intake. We also investigated whether targeting oliguria reversal affected these pa...
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial
BACKGROUND: Etomidate is perceived as preserving haemodynamic stability during induction of anaesthesia. It is also associated with adrenocortical dysfunction. The risk/benefit relationship is controversial. OBJECTIVES: We tested the hypotheses that single-dose etomidate increases cumulative vasopressor requirement, time to extubation and length of stay in the ICU. DESIGN: Double-blind randomised controlled trial. SETTING: Bern University Hospital, Switzerland, from November 2006 to December 2009. PATIENTS: There were 90 patients undergoing coronary artery bypass grafts (CABG) and 40 patients undergoing mitral valve su...
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Cardiac anaesthesia Source Type: research

Identifying optimal heparin management during cardiopulmonary bypass in obese patients: A prospective observational comparative study
The objective is to compare the effects of heparin injection based on TBW on haemostatic parameters between obese and nonobese patients during cardiac surgery and to calculate the optimal heparin regimen. DESIGN: Prospective comparative study. SETTING: University hospital. PATIENTS: Two groups of 50 patients (BMI≥ or (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Cardiac anaesthesia Source Type: research

Cardiac troponins and volatile anaesthetics in coronary artery bypass graft surgery: A systematic review, meta-analysis and trial sequential analysis
The objective was to demonstrate that clinical studies investigating the cardioprotective effect of volatile anaesthetics on cardiac troponins in CABG are no longer warranted. We also investigated the effect of volatile anaesthetics on cardiac enzymes in off-pump cardiac surgery. DESIGN: Systematic review of randomised clinical trials, meta-analyses and trial sequential analysis (TSA). DATA SOURCES: Trials between January 1985 and March 2015 were obtained from electronic databases (Medline, Excerpta Medica Database (EMBASE), Cochrane Controlled Trial Register, abstracts from major anaesthesiology and cardiology journals ...
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Cardiac anaesthesia Source Type: research

Cardiac troponins and volatile anaesthetics in on-pump coronary surgery: How much longer do we need to state the obvious?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Invited commentary Source Type: research

Enhanced recovery programmes for the elderly
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Editorial Source Type: research

Provision of an on-call service for regional anaesthesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Variability by country in the European Neuroanaesthesia and Critical Care Interest Group subarachnoid haemorrhage survey
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Ease of insertion of nasogastric tube, before or after endotracheal intubation under general anaesthesia: A randomised study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The use of rocuronium and sugammadex in paediatric renal transplantation: Two case reports
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Postanaesthesia pulmonary complications after use of muscle relaxants in Europe: Study protocol of the POPULAR study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

A rare case of sevoflurane hypersensitivity
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Intraoperative anaphylaxis to neuromuscular blocking agents: the incidence over 9 years at two tertiary hospitals in South Korea: A retrospective observational study
CONCLUSION: Among commonly used NMBAs, rocuronium appears to have the highest incidence of anaphylaxis. Our findings suggest that future prospective investigation for NMBA-induced anaphylaxis should use internationally agreed skin test protocols. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Pharmacology Source Type: research

The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation: An in-vitro study
BACKGROUND: Management of ticagrelor-induced bleeding is challenging, as no antidote is currently available. Platelet transfusion, usually proposed to reverse antiplatelet drugs, has been suggested to be ineffective but few data are available. OBJECTIVE: To assess the efficacy of platelet supplementation to restore platelet aggregation inhibited by ticagrelor. DESIGN: In vitro study. SETTING: Blood samples were obtained from the French Blood Bank Institute. PARTICIPANTS: Healthy blood donors. INTERVENTIONS: Whole blood from healthy donors was spiked with ticagrelor or aspirin (used as a positive control). MAIN OUTCOM...
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Pharmacology Source Type: research

Impact of nitrous oxide on the haemodynamic consequences of venous carbon dioxide embolism: An experimental study
CONCLUSION: The findings of this study may alleviate concerns that the use of N2O, as a part of a balanced general anaesthesia technique, may have greater adverse consequences should embolisation of pneumoperitoneal gas containing N2O occur. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Pharmacology Source Type: research

Plasma levels of chemokine ligand 20 and chemokine receptor 6 in patients with sepsis: A case control study
BACKGROUND: Chemokine ligand 20 (CCL20) is a chemokine released by mainly liver and blood leucocytes. Particularly under pro-inflammatory circumstances it triggers chemotaxis of lymphocytes and dendritic cells via activating receptor chemokine receptor 6 (CCR6) that is specific to it. In experimental sepsis models, the chemokine–receptor pair has been identified as a potential pathophysiological axis affecting mortality. OBJECTIVE: Measurement of CCL20 and CCR6 plasma levels in septic patients compared with postsurgical, nonseptic patients. DESIGN: Case control study. SETTING: Surgical ICUs of the Department of An...
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Outcome Source Type: research

Postoperative shoulder pain after laparoscopic hysterectomy with deep neuromuscular blockade and low-pressure pneumoperitoneum: A randomised controlled trial
CONCLUSION: Deep NMB and low-pressure pneumoperitoneum (8 mmHg) reduced the incidence of shoulder pain after laparoscopic hysterectomy in comparison to moderate NMB and standard-pressure pneumoperitoneum (12 mmHg). TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT01722097. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Outcome Source Type: research

Warming before and after epidural block before general anaesthesia for major abdominal surgery prevents perioperative hypothermia: A randomised controlled trial
BACKGROUND: Epidural analgesia (EDA) is known to be an independent risk factor for perioperative hypothermia and its many known adverse effects. Combined general and epidural anaesthesia decreases intraoperative core temperature more rapidly than general anaesthesia alone. Hence, adequate warming procedures are needed for these patients. OBJECTIVE: We evaluated the effects of active skin-surface warming before and/or after initiation of EDA during general anaesthesia as a procedure to prevent perioperative hypothermia. DESIGN: A randomised controlled trial. SETTING: Department of Anaesthesiology in a general hospital in...
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Outcome Source Type: research

Risk prediction model for respiratory complications after lung resection: An observational multicentre study
CONCLUSION: In this external validation, the CPRPC performed poorly despite its simplicity. The CPRPC was not a useful scale in our cohort. In contrast, we used a more accurate score to predict the occurrence of PPCs in our cohort. It is based on age, smoking status and predicted postoperative forced expiratory volume in 1 s. We propose that our formula should be externally validated. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Outcome Source Type: research

Swedish surgical outcomes study (SweSOS): An observational study on 30-day and 1-year mortality after surgery
CONCLUSION: Mortality rate increased almost five-fold at 1 year compared with 30-day mortality after surgery, demonstrating a significantly sustained long-term risk of death in this surgical population. In Sweden, factors associated with long-term postoperative mortality were age, number of comorbidities and surgical urgency. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Outcome Source Type: research

Perioperative medicine and mortality after elective and emergency surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Invited commentary Source Type: research

Role of regional anaesthesia in disaster medicine: field hospital experience after the 2015 Nepal Earthquake
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Editorial Source Type: research

Anaesthesia in the wake of the Nepal earthquake: Experience and immediate lessons learnt
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 7, 2016 Category: Anesthesiology Tags: Editorial Source Type: research

The VivaSight-DL double-lumen tube with integrated camera
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: preventing hypoxia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Preventing hypoxia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: blind intubation through Air-Q SP laryngeal mask in morbidly obese patients
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Blind intubation through Air-Q SP laryngeal mask in morbidly obese patients
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: how to minimise ventilator-induced lung injury in transplanted lungs
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

How to minimise ventilator-induced lung injury in transplanted lungs
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The effects of intraoperative lung protective ventilation with positive end-expiratory pressure on blood loss during hepatic resection surgery: A secondary analysis of data from a published randomised control trial (IMPROVE)
CONCLUSION: During hepatic surgery, mechanical ventilation using PEEP within a multi-faceted lung protective strategy was not associated with increased bleeding compared with non-protective ventilation using zero PEEP. TRIAL REGISTRATION: The current study was not registered. The original Intraoperative Protective Ventilation study was registered on clinicaltrials.gov; number NCT01282996. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Ventilation Source Type: research

Neurally adjusted ventilatory assist feasibility during anaesthesia: A randomised crossover study of two anaesthetics in a large animal model
CONCLUSION: NAVA is feasible during ketamine-propofol and ketamine-sevoflurane anaesthesia in pigs. Sevoflurane promotes lower Vt, and affects NME and NVE less than propofol. Our data warrant studies of NAVA in humans undergoing anaesthesia. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Ventilation Source Type: research

Effects of dexmedetomidine on oxygenation and lung mechanics in patients with moderate chronic obstructive pulmonary disease undergoing lung cancer surgery: A randomised double-blinded trial
The objective is to determine whether dexmedetomidine improves oxygenation and lung mechanics in patients with moderate COPD during lung cancer surgery. DESIGN: A randomised, double-blinded, placebo-controlled study. SETTING: Single university hospital. PARTICIPANTS: Fifty patients scheduled for video-assisted thoracoscopic surgery who had moderate COPD. Patients were randomly allocated to a control group or a Dex group (n = 25 each). INTERVENTIONS: In the Dex group, dexmedetomidine was given as an initial loading dose of 1.0 μg kg−1 over 10 min followed by a maintenance dose of 0.5 μg kg&minu...
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Ventilation Source Type: research

Low-positive pressure ventilation improves non-hypoxaemic apnoea tolerance during ear, nose and throat pan-endoscopy: A randomised controlled trial
The objective was to determine whether or not pre-oxygenation with PSV increases the duration of non-hypoxaemic apnoea in non-obese patients during pan-endoscopy. DESIGN: A randomised, controlled trial. SETTING: Amiens University Hospital, France. PATIENTS: Fifty patients scheduled for ENT pan-endoscopy with a BMI lower than 35 kg m−2. INTERVENTION: Patients scheduled for pan-endoscopy were enrolled to receive either 100% oxygen at neutral pressure (the control group) or 100% oxygen with positive-pressure ventilation (a positive inspiratory pressure of 4 cmH2O and a positive end-expiratory pressure of 4 c...
Source: European Journal of Anaesthesiology - March 3, 2016 Category: Anesthesiology Tags: Ventilation Source Type: research