Development and performance testing of the low-cost, 3D-printed, smartphone-compatible ‘Tansen Videolaryngoscope’ vs. Pentax-AWS videolaryngoscope vs. direct Macintosh laryngoscope: A manikin study
BACKGROUND While videolaryngoscopes help in the management of difficult airways, they remain too expensive for those with limited resources. We have developed a robust, re-usable, low-cost videolaryngoscope at United Mission Hospital Tansen, Nepal, by combining a smartphone-compatible endoscope capable of capturing still and video images with a three dimensional-printed, channelled, hyperangulated blade. The computer-aided design file for the videolaryngoscope blade was emailed and printed in London before evaluation of its performance on a difficult airway manikin. OBJECTIVE To benchmark the intubation performance of...
Source: European Journal of Anaesthesiology - October 9, 2020 Category: Anesthesiology Tags: Airway Source Type: research

Apolipoprotein E ε4 and cognitive function after surgery in middle-aged and elderly Danish twins
CONCLUSION No evidence was found of more pronounced long-term deterioration in cognitive function after surgery among APOE ε4 carriers, but elderly APOE ε4 carriers in general performed worse on the cognitive tests than noncarriers. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 9, 2020 Category: Anesthesiology Tags: Regional anaesthesia Source Type: research

Ultrasound-guided interscalene block combined with intermediate or superficial cervical plexus block for clavicle surgery: A randomised double blind study
This study aims to delineate the relative effectiveness between interscalene brachial plexus block with either intermediate cervical plexus or superficial cervical plexus block (CPB) as the anaesthetics for clavicular surgery. DESIGN A randomised, double-blind prospective study. SETTING Single-centre, tertiary care medical college and research institute. PATIENTS Fifty patients with American Society of Anesthesiologist's (ASA) grade I to III, aged 18 to 70 years, scheduled for clavicular surgery, during May 2018 to April 2019 were enrolled in this study. INTERVENTION All patients received interscalene block wit...
Source: European Journal of Anaesthesiology - October 9, 2020 Category: Anesthesiology Tags: Regional anaesthesia Source Type: research

Effect of two different pre-operative exercise training regimens before colorectal surgery on functional capacity: A randomised controlled trial
CONCLUSION Both MICT and HIIT enhanced pre-operative functional capacity. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT03361150. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 9, 2020 Category: Anesthesiology Tags: Regional anaesthesia Source Type: research

Genetic variability in postoperative nausea and vomiting: A systematic review
CONCLUSION There is a genetic susceptibility to the development of PONV. Two single nucleotide polymorphisms (SNPs), the CHRM3 rs2165870 and the KCNB2 rs349358 SNP, seem to have a major influence on PONV incidence, at least in Caucasians. Both SNPs were primarily identified in a GWAS and this association may lead to a better understanding of the disease aetiology. Further high-quality studies are needed to reveal more insights in genetic PONV susceptibility, particularly so in non-Caucasian ethnicities. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 9, 2020 Category: Anesthesiology Tags: Regional anaesthesia Source Type: research

BIG FIVE strategies for survival following out-of-hospital cardiac arrest
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 9, 2020 Category: Anesthesiology Tags: Editorial Source Type: research

Perioperative care of the elderly: clinical and organizational aspects
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Book review Source Type: research

Extracorporeal carbon dioxide removal may prevent the need for extracorporeal membrane oxygenation in severe respiratory failure: A cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

The effectiveness of electromyographic and acceleromyographic-based neuromuscular monitoring in ventilated ICU patients: A prospective feasibility study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Lung ultrasound modifications induced by fibreoptic bronchoscopy may improve early bedside ventilator-associated pneumonia diagnosis: A case series
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Altmetrics versus traditional bibliometrics: Short-time lag and short-time life?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Methadone for postoperative analgesia: contribution of N-methyl-d-aspartate receptor antagonism: A randomised controlled trial
CONCLUSION Methadone provides effective control of acute postoperative pain, independently, by modulation of the hyperalgesia mechanism. CLINICAL TRIAL REGISTRATION ClinicalTrials.gov, no.: NCT01594047. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Pain Source Type: research

Pre-operative chronic opioid or glucocorticoid use and mortality after noncardiac surgery: A retrospective cohort study
BACKGROUND The chronic use of opioids and glucocorticoids is associated with serious side effects. Moreover, both medications are related to poor long-term postoperative outcomes. OBJECTIVE The study aimed to investigate the association between pre-operative chronic opioid and glucocorticoid use and 90-day mortality after noncardiac surgery. DESIGN Retrospective, population-based cohort study. SETTING Single tertiary academic hospital. PATIENTS The study enrolled adult (≥18 years of age) patients admitted to Seoul National University Bundang Hospital, between January 2012 and December 2018 for planned, ele...
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Pain Source Type: research

Cardiac output estimation by pulse wave analysis using the pressure recording analytical method and intermittent pulmonary artery thermodilution: A method comparison study after off-pump coronary artery bypass surgery
CONCLUSION Using the system's electronic waveform filter PRAM-CO shows good agreement and trending ability compared with PATD-CO in adults after off-pump coronary artery bypass surgery. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Cardiac anaesthesia Source Type: research

Presepsin for pre-operative prediction of major adverse cardiovascular events in coronary heart disease patients undergoing noncardiac surgery: Post hoc analysis of the Leukocytes and Cardiovascular Peri-operative Events-2 (LeukoCAPE-2) Study
CONCLUSION Increased pre-operative presepsin independently predicted 30-day MACCE in CAD patients undergoing major noncardiac surgery. Complementing cardiovascular risk prediction by inflammatory biomarkers, such as presepsin, offers potential to improve peri-operative care. However, as prediction accuracy of presepsin was only moderate, further validation studies are needed. TRIAL REGISTRATION Clinicaltrials.gov: NCT03105427. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Cardiac anaesthesia Source Type: research

Very early changes in serum creatinine are associated with 30-day mortality after cardiac surgery: A cohort study
BACKGROUND Acute kidney injury predicts adverse outcomes after cardiac surgery. OBJECTIVES To determine whether ultra-short-term changes (within 120 min) in serum creatinine (SCrea) levels after cardiac surgery predict clinical outcomes (30-day mortality). DESIGN Observational cohort study. SETTING Austrian tertiary referral centre. PATIENTS A total of 7651 patients scheduled to undergo elective cardiac surgery. MAIN OUTCOME MEASURES We analysed SCrea levels measured pre-operatively (baseline) and within 120 min after surgery. We also adjusted the postoperative SCrea levels for fluid balance. Patients ...
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Cardiac anaesthesia Source Type: research

U-shaped relationship between pre-operative plasma fibrinogen levels and severe peri-operative bleeding in cardiac surgery
CONCLUSION We reported a U-shaped relationship between severe peri-operative bleeding and pre-operative fibrinogen levels. While a low-level of fibrinogen appears to be associated with a high risk of bleeding, a high level does not necessarily protect the patient against such a risk and could even be a risk factor for peri-operative bleeding. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Coagulation Source Type: research

Comparison of fresh frozen plasma vs. coagulation factor concentrates for reconstitution of blood: An in vitro study
BACKGROUND Many trauma centres have adopted the administration of fixed ratios of packed red blood cells (PRBCs), platelet concentrates and fresh frozen plasma (FFP) for bleeding patients. However, the haemostatic efficacy of this concept is not well proven. OBJECTIVE Our objective was to characterise the haemostatic profile of different ratios (2 : 1 : 1, 1 : 1 : 1 and 1 : 1 : 2) of PRBCs, platelet concentrates and FFP in comparison with coagulation factor concentrates (fibrinogen and/or prothrombin complex concentrate). DESIGN An in vitro study. SETTING Research laboratories of the depa...
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Coagulation Source Type: research

Idarucizumab for dabigatran reversal in daily clinical practice: A case series
CONCLUSION Our first experiences with idarucizumab use in daily-care settings support a rapid and efficient decrease in the anticoagulant effect of dabigatran in emergency situations. Late re-occurrence of dabigatran effect was noted in a subset of patients with severe renal failure. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Coagulation Source Type: research

Development and validation of an instrument to measure nursing workload in the postanaesthesia care unit: An observational study
BACKGROUND There are no instruments specifically developed for the measurement of nursing workload in postanaesthesia care units (PACUs). An objective and valid instrument is essential for planning work flow and staffing in this unique hospital environment that encompasses elements of elective and acute postsurgical care. Previous studies show that increased workload is associated with increased complication rates in ICUs. Thus, workload assessment may be an important tool for improving postsurgical outcomes. OBJECTIVE The aim of this study was to develop and validate a postanaesthesia workload instrument (PAWI) for m...
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Safety and quality Source Type: research

Erroneous neuraxial administration of neuromuscular blocking drugs: Clinical and human factors analysis
CONCLUSION Following the epidural injection of NMBDs the effects are delayed and prolonged. There was no serious morbidity reported following neuraxial administration of the NMBDs used in current practice. Perceptual errors resulting in incorrect syringe choice were the commonest cause. Four measures can be introduced to reduce such errors. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Safety and quality Source Type: research

Patient satisfaction with intravenous regional anaesthesia or an axillary block for minor ambulatory hand surgery: A randomised controlled study
CONCLUSION IVRA and axillary brachial plexus block result in comparably high patient satisfaction in ambulatory hand surgery. CLINICAL TRIAL REGISTRATION EudraCT 2016-002325-11. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Safety and quality Source Type: research

Pre-induction checklists and discomfort in patients. An observational study
CONCLUSION Patients experience far less discomfort observing the use of pre-induction checklists than anaesthesia providers expect. Patients value the potential safety benefit significantly higher than anaesthesia providers. These results further support the implementation of peri-operative checklists in the operating room environment. TRIAL REGISTRATION The current observational study had no intervention, therefore, was not registered. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Safety and quality Source Type: research

Mandatory cardiopulmonary resuscitation competencies for undergraduate healthcare students in Europe: A European Resuscitation Council guidance note
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Editorials Source Type: research

Safety first: Checking the anaesthesia machine
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Editorials Source Type: research

Preoperative ultrasonographic evaluation of inferior vena cava collapsibility index and caval aorta index
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Comparison of continuous versus patient-controlled dosing regimen in peripheral nerve blocks for postoperative pain management after lower extremity surgery: A data-base analysis of 1293 cases
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Efficacy of incisional infiltration and intraperitoneal instillation of ropivacaine for the management of pain after laparoscopic sleeve gastrectomy: A randomised clinical trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Acute thalamic haemorrhagic stroke after combined spinal–epidural anaesthesia in pregnancy: A case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

The seventh thoracic vertebral level is more reliably identified by point of care ultrasound than by palpation of the inferior angle of the scapula: A case series
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Ultrasound and pressure-guided thoracic paravertebral block: A preliminary investigation
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Clinical effectiveness of ultrasound-guided dual transversus abdominis plane block for postoperative analgesia in open abdominal aortic surgery patients: The randomised, double-blind ETAP trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: deep neuromuscular blockade reduces intra-operative blood loss
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Deep neuromuscular blockade reduces intra-operative blood loss
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: reintubation in the ICU versus in the operating room in cardiac surgery patients
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Reintubation in the ICU versus in the operating room in cardiac surgery patients
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Oral fluid intake during the first stage of labour: A randomised trial
CONCLUSION The current study reveals that the percentage of pregnant women with an ‘empty stomach’, defined by an antral CSA less than 300 mm2 in a semirecumbent position with a 45-degree head-up tilt, was comparable at full cervical dilation among those who remained nil by mouth and those allowed to drink up to 400 ml for 90 min after their randomisation. TRIAL REGISTRATION Clinicaltrials.gov identifier: NCT 02362815. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Obstetric anaesthesia Source Type: research

Prophylactic norepinephrine infusion or leg wrapping for postspinal hypotension in elective caesarean delivery: A randomised, double-blind, placebo-controlled trial
BACKGROUND Because of its alpha and beta agonist properties, norepinephrine infusion is currently being studied for the prevention of spinal hypotension during caesarean delivery. Vasopressor infusions are not always possible if there is an unavailability of infusion pumps. Leg wrapping with crepe bandage is an effective technique for prevention of postspinal hypotension and could be useful in resource-poor settings. OBJECTIVE The aim of this study was to compare the incidence of hypotension with norepinephrine infusion or leg wrapping with a control group in women undergoing caesarean delivery with spinal anaesthesia...
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Obstetric anaesthesia Source Type: research

Investigating the association between labour epidural analgesia and postpartum depression: A prospective cohort study
CONCLUSION Our study did not demonstrate an association between PPD at 3 months postdelivery and labour epidural analgesia. TRIAL REGISTRATION NCT01174875. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Obstetric anaesthesia Source Type: research

Effects of adding a combined femoral and sciatic nerve block with levobupivacaine and clonidine to general anaesthesia in femoropopliteal bypass surgery: A randomised, double-blind, controlled trial
CONCLUSION Combining the two regional blocks improves the quality of postoperative care in this frail population, probably by reducing the amount of peri-operative opioid. TRIAL REGISTRATION ClinicalTrials.gov (ref. NCT01785693). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Minimum effective volume of 0.5% ropivacaine for ultrasound-guided costoclavicular brachial plexus block: A dose finding study
CONCLUSION The MEV90 of 0.5% ropivacaine required to produce surgical anaesthesia with an ultrasound-guided CC-BPB is 20.9 ml. CLINICAL TRIAL REGISTRATION The trial was registered with the Chinese Clinical Trials Registry (www.chictr.org.cn, ChiCTR-IOR-15007515, principal investigator: Manoj Kumar Karmakar, date of registration: 4 December 2015). CLINICAL TRIAL NUMBER AND REGISTRY URL ChiCTR-IOR-15007515, Chinese Clinical Trials Registry (www.chictr.org.cn). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Transversus abdominis plane block versus quadratus lumborum block type 2 for analgesia in renal transplantation: A randomised trial
CONCLUSION The reduction of fentanyl consumption in the first 24 h after renal transplantation with no difference in pain intensity and patient satisfaction shows a beneficial effect of one-sided QLB type 2 over a one-sided TAPB in regards to postoperative analgesia. However, the reduction in opioid consumption did not affect the frequency of opioid-related adverse effects. TRIAL REGISTRATION ClinicalTrials.gov ID: NCT02783586. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Subarachnoid block and ultrasound-guided transversalis fascia plane block for caesarean section: A randomised, double-blind, placebo-controlled trial
BACKGROUND After caesarean section, maternal postoperative comfort is critical to allow the new mother to care for her baby. Insufficient pain relief during the postoperative period may delay maternal/infant bonding and, in addition, such pain has been linked to subsequent depression and chronic pain. Caesarean section is commonly performed with a Pfannenstiel incision, and a transversalis fascia plane (TFP) block provides postoperative analgesia in the T12 and L1 dermatomes. OBJECTIVE The aim of this study was to investigate the effect of the TFP block on postoperative opioid consumption and pain scores in patients u...
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Dislocation rates of perineural catheters placed either perpendicular or parallel to the femoral nerve: A randomised controlled trial
CONCLUSION Rotating the ultrasound probe to the long-axis in-plane view enabled examination of the catheter position when it was placed parallel to the nerve. The parallel placement of the catheter required more time, but did not significantly improve dislocation rate, pain scores or sensory blockade. TRIAL REGISTRATION Clinicaltrials.gov identifier: NCT03693755. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Transverse vs. parasagittal in-plane approaches in ultrasound-guided paravertebral block using a microconvex probe: A randomised controlled trial
CONCLUSION There were no clinically significant differences between approaches for continuous ultrasound-guided thoracic paravertebral block using a microconvex probe, and both approaches achieved a high rate of correct catheter placement. TRIAL REGISTRATION UMIN Clinical Trials Registry identifier: UMIN000015988. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Haematoma, abscess or meningitis after neuraxial anaesthesia in the USA and the Netherlands: A closed claims analysis
CONCLUSIONS Claims of spinal haematoma were often related to errors in antihaemostatic medication and delay in diagnosis and/or treatment. Spinal abscess claims were related to emergency interventions and lack of sterility. We wish to highlight these potential preventable causes, both when performing the neuraxial procedure and during postprocedural care of patients. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Risk and prognosis of COVID-19 in patients treated with renin–angiotensin–aldosterone inhibitors
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Editorial Source Type: research

Paediatric anaesthesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 29, 2020 Category: Anesthesiology Tags: Book review Source Type: research

Anaesthesia and orphan disease: A patient with neuromyotonia undergoing single lung ventilation
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 29, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: Phelan–McDermid syndrome
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 29, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research