Is ‘anxiety sensitivity’ predictive of postoperative nausea and vomiting?: A prospective observational study
CONCLUSION In addition to the well established risk factors, anxiety sensitivity can help to predict the risk of PONV. It seems justifiable to add psychological factors such as anxiety sensitivity to PONV risk-scores. PONV prophylaxis should be considered when anxiety sensitivity is high. TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT01875120. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Postoperative nausea and vomiting Source Type: research

Improvement in postoperative pain control by combined use of intravenous dexamethasone with intravenous dexmedetomidine after interscalene brachial plexus block for arthroscopic shoulder surgery: A randomised controlled trial
BACKGROUND Intravenous dexamethasone or dexmedetomidine is reported to prolong the duration of analgesia after single-shot interscalene brachial plexus block (ISBPB). However, the effect of co-administration of these agents on the duration of analgesia has not been evaluated. OBJECTIVES We evaluated the difference in time to first rescue analgesic request between patients receiving co-administered intravenous dexamethasone and dexmedetomidine and patients receiving intravenous dexamethasone alone after single-shot ISBPB for arthroscopic shoulder surgery. DESIGN A randomised controlled study. SETTING A single ter...
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Metamizole vs. ibuprofen at home after day case surgery: A double-blind randomised controlled noninferiority trial
CONCLUSION Paracetamol/metamizole and paracetamol/ibuprofen are equally effective in treatment of acute postoperative pain at home after ambulatory surgery with comparable patient satisfaction levels. TRIAL REGISTRATION European Union Clinical Trials Register 2015-003987-35. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Genetics and postsurgical neuropathic pain: An ancillary study of a multicentre survey
CONCLUSION This is the first genetic association study specifically investigating the occurrence of persistent postsurgical neuropathic pain. Its results help target future research to better understand the mechanisms of peripheral neuropathic pain. TRIAL REGISTRATION ClinicalTrials.gov (ref. NCT00812734). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Comparison of pre-oxygenation using spontaneous breathing through face mask and high-flow nasal oxygen: A randomised controlled crossover study in healthy volunteers
BACKGROUND High-flow nasal oxygen (HFNO) therapy has been proposed for pre-oxygenation before intubation, but the end-tidal fraction of oxygen (ETO2) obtained remains unknown. OBJECTIVE(S) To compare the ETO2 following a 3 min pre-oxygenation with HFNO and face mask. SETTING Operating room in a primary university hospital. DESIGN A randomised crossover study. PARTICIPANTS Fifty healthy volunteers. INTERVENTIONS Participants were randomly pre-oxygenated through spontaneous breathing 100% oxygen in a face mask and with HFNO (mouth closed, heated and humidified gas flow at 60 l min–1). In the face...
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Ventilation Source Type: research

Flow-controlled ventilation during ear, nose and throat surgery: A prospective observational study
CONCLUSION FCV achieves adequate PetCO2 levels with minute volume and Δp in the normal range. Tritube's high flow resistance may increase the likelihood of tube dislocations if the patient coughs. Although further evaluation is necessary, FCV provides a new option for short-term mechanical ventilation. The successful operation of FCV with narrow-bore tubes contributes to the armamentarium for airway management. TRIAL REGISTRATION DRKS00013312 (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Ventilation Source Type: research

Intra-operative high inspired oxygen fraction does not increase the risk of postoperative respiratory complications: Alternating intervention clinical trial
CONCLUSION Intra-operative hyperoxia did not change the postoperative SpO2/FiO2 ratio or the risk for pulmonary complications. Clinicians should not refrain from using hyperoxia for fear of provoking respiratory complications. TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT01777568. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Ventilation Source Type: research

Intra-operative high inspired oxygen during open abdominal surgery and postoperative pulmonary complications: From physiology to individualised strategies
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 4, 2019 Category: Anesthesiology Tags: Invited commentary Source Type: research

Central venous-to-arterial PCO2 difference, arteriovenous oxygen content and outcome after adult cardiac surgery with cardiopulmonary bypass: A prospective observational study
BACKGROUND Rapid identification and treatment of tissue hypoxia reaching anaerobiosis (dysoxia) may reduce organ failure and the occurrence of major postoperative complications (MPC) after cardiac surgery. The predictive ability of PCO2-based dysoxia biomarkers, central venous-to-arterial PCO2 difference (ΔPCO2) and ΔPCO2 to arteriovenous oxygen content difference ratio, is poorly studied in this setting. OBJECTIVES We evaluated the ability of PCO2-based tissue dysoxia biomarkers, blood lactate concentration and central venous oxygen saturation measured 2 h after admission to the ICU as predictors of MPC...
Source: European Journal of Anaesthesiology - March 7, 2019 Category: Anesthesiology Tags: Haemodynamics Source Type: research

Opioid-free anaesthesia: Still a debate?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 7, 2019 Category: Anesthesiology Tags: Invited commentary Source Type: research

Anesthesia outside the Operating Room
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Book review Source Type: research

Safety of a powder-free latex allergy protocol in the operating theatre: A prospective, observational cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Safety of propofol use in patients allergic to soy or peanut: A retrospective observational cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Effect of high-flow nasal cannula versus conventional facemask ventilation for patients undergoing modified electroconvulsive therapy: A randomised controlled, noninferiority trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Two-lung ventilation during prone minimally invasive thorascopic oesophagectomy: A case series
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: anaesthesia and endovascular therapy in patients with acute ischaemic stroke
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and endovascular therapy in patients with acute ischaemic stroke
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: implementation of closed-loop-assisted intra-operative goal-directed fluid therapy during surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Implementation of closed-loop-assisted intra-operative goal-directed fluid therapy during surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Pre-operative ultrasonographic evaluation of inferior vena cava collapsibility index and caval aorta index as new predictors for hypotension after induction of spinal anaesthesia: A prospective observational study
CONCLUSION Pre-operative IVCCI and IVC : Ao index are good predictors of the occurrence of PSAH. However, IVC : Ao index is a more powerful predictor than IVCCI. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Haemodynamics Source Type: research

The haemodynamic instability score: Development and internal validation of a new rating method of intra-operative haemodynamic instability
BACKGROUND There is no consensus on how to define haemodynamic instability during general anaesthesia. Patients are often classified as stable or unstable based solely on blood pressure thresholds, disregarding the degree of instability. Vasoactive agents and volume therapy can directly influence classification but are usually not considered. OBJECTIVE To develop and validate a scoring tool to quantify the overall degree of haemodynamic instability. DESIGN Retrospective observational study. SETTING University hospital. PATIENTS The development cohort consisted of 50 patients undergoing high-risk surgery with ...
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Haemodynamics Source Type: research

Central venous-to-arterial PCO2 difference, arteriovenous oxygen content and outcome after adult cardiac surgery with cardiopulmonary bypass: A prospective observational study
BACKGROUND Rapid identification and treatment of tissue hypoxia reaching anaerobiosis (dysoxia) may reduce organ failure and the occurrence of major postoperative complications (MPC) after cardiac surgery. The predictive ability of PCO2-based dysoxia biomarkers, central venous-to-arterial PCO2 difference (ΔPCO2) and ΔPCO2 to arteriovenous oxygen content difference ratio, is poorly studied in this setting. OBJECTIVES We evaluated the ability of PCO2-based tissue dysoxia biomarkers, blood lactate concentration and central venous oxygen saturation measured 2 h after admission to the ICU as predictors of MPC...
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Haemodynamics Source Type: research

Programmed intermittent bolus infusion versus continuous infusion of 0.2% levobupivacaine after ultrasound-guided thoracic paravertebral block for video-assisted thoracoscopic surgery: A randomised controlled trial
CONCLUSION Our findings suggest that postoperative pain and opioid usage are similar with either programmed intermittent bolus infusion or continuous infusion after thoracic paravertebral block. Programmed intermittent bolus infusion provides a wider sensory blockade and could benefit patients requiring a wider extent of anaesthesia. TRIAL REGISTRATION UMIN Clinical Trials Registry (UMIN-CTR; URL: http://umin.ac.jp/ctr/, ID: UMIN000023378). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Loco-regional anaesthesia Source Type: research

A comparison of the analgesic efficacy of local infiltration analgesia vs. intrathecal morphine after total knee replacement: A randomised controlled trial
CONCLUSION We conclude that LIA conferred superior analgesia compared with intrathecal morphine 0.3 mg at 24 and 48 h following TKA. TRIAL REGISTRATION Clinicaltrials.gov identifier: NCT01312415. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Loco-regional anaesthesia Source Type: research

Local infiltration anaesthesia versus sciatic nerve and adductor canal block for fast-track knee arthroplasty: A randomised controlled clinical trial
BACKGROUND Local infiltration anaesthesia (LIA) was introduced as an innovative analgesic procedure for enhanced recovery after primary total knee arthroplasty (TKA). However, LIA has never been compared with analgesia based on an adductor canal catheter and a single-shot sciatic nerve block. OBJECTIVE To evaluate two analgesic regimens for TKA comparing mobility, postoperative pain and patient satisfaction. DESIGN Two-group randomised, controlled clinical trial. SETTING Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Germany between April and August 2017. PATIENTS Adults undergoi...
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Loco-regional anaesthesia Source Type: research

Opioid-free anaesthesia: Con: it is too early to adopt opioid-free anaesthesia today
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Editorials Source Type: research

Opioid-free anaesthesia: Pro: damned if you don’t use opioids during surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Editorials Source Type: research

Opioid-free anaesthesia: Still a debate?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 4, 2019 Category: Anesthesiology Tags: Invited commentary Source Type: research

Levobupivacaine scalp nerve block: haemodynamics and anaesthesia requirements in supratentorial craniotomy P 096: Erratum
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Erratum Source Type: research

Use of palonosetron and ondansetron in the prophylaxis of postoperative nausea and vomiting in women 60 years of age or older undergoing laparoscopic cholecystectomy: A randomised double-blind study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Intra-operative difficult airway identification and critical airway communication: how effective are we?: A retrospective review of 6318 cases
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Use of the Totaltrack VLM as a rescue device following failed tracheal intubation
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Calculation improves the estimation of needle depth from skin to thoracic epidural space in infants
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Laryngotracheal stenosis in children following cardiac surgery: A retrospective review
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

The effect of virtual reality bronchoscopy simulator training on performance of bronchoscopic-guided intubation in patients: A randomised controlled trial
CONCLUSION We conclude, posttraining performance of FOB intubation, as measured by intubation time and GRS, improved in Group SIM, while it was unchanged in the Group CON. The ORSIM simulator may be a useful adjunct in acquiring FOB intubation skills. CLINICAL TRIAL NUMBER AND REGISTRY ClinicalTrials.gov ID: NCT02699242. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Airway management Source Type: research

Measurement of forces applied using a Macintosh direct laryngoscope compared with a Glidescope video laryngoscope in patients with predictors of difficult laryngoscopy: A randomised controlled trial
BACKGROUND In patients with predictive features associated with easy direct laryngoscopy, videolaryngoscoy with the GlideScope has been shown to require less force when compared with Macintosh direct laryngoscopy. OBJECTIVE The aim of this study was to compare forces applied with Glidescope vs. Macintosh laryngoscopes in patients with predictive features associated with difficult direct laryngoscopy. DESIGN A randomised study. SETTING Toronto General Hospital, a university tertiary centre in Canada. PATIENTS Forty-four patients aged over 18 years, with one or more features of difficult intubation, undergoing ...
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Airway management Source Type: research

Use of tracheal ultrasound combined with clinical parameters to select left double-lumen tube size: A prospective observational study
BACKGROUND Left double-lumen tubes (LDLTs) are used in thoracic surgery to allow one-lung ventilation. Their size is usually chosen on the basis of clinical parameters (height, sex). Double-lumen endobronchial tubes are frequently undersized/oversized, risking tube displacement or tracheal trauma. A correlation between ultrasound tracheal diameter and left main bronchus dimension has been demonstrated. OBJECTIVES We hypothesised that the insertion of undersized/oversized double-lumen tubes is frequent when the size is selected using standard criteria, and that the use of ultrasound to estimate tracheal diameter may he...
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Airway management Source Type: research

Bupivacaine infiltration in children for postoperative analgesia after tonsillectomy: A randomised controlled trial
BACKGROUND Adenotonsillectomy is a frequently performed procedure in paediatric day-case surgery. Postoperative pain can be significant and standard analgesia protocols are often insufficient. OBJECTIVE Our primary objective was to investigate if infiltration of the peritonsillar space with bupivacaine would reduce the need for postoperative opioids compared with pre-emptive intravenous tramadol. DESIGN A double-blind, randomised controlled trial. SETTING Ambulatory surgical day care centre, University Hospitals of Leuven, Belgium, from January 2012 to September 2016. PATIENTS Two hundred children, between 4 ...
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Ultrasound-guided vs. palpation-guided techniques for radial arterial catheterisation in infants: A randomised controlled trial
CONCLUSION The current study demonstrated that the ultrasound-guided technique for radial arterial catheterisation in infants effectively improved first-pass success rate and also reduced the number of attempts required. TRIAL REGISTRATION ClinicalTrials.gov NCT02795468. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Comparison of rocuronium requirement in children with continuous infusion versus intermittent bolus: A randomised controlled trial
CONCLUSION In children undergoing general anaesthesia, the dose of rocuronium given by continuous administration was less than that with intermittent bolus. TRIAL REGISTRATION ClinicalTrials.gov (identifier: NCT03060707). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Epidemiology and incidence of severe respiratory critical events in ear, nose and throat surgery in children in Europe: A prospective multicentre observational study
BACKGROUND Ear, nose and throat (ENT) surgery, the most frequently performed surgical procedure in children, is a strong predictor for peri-operative respiratory complications. However, there is no clear information about peri-operative respiratory severe critical events (SCEs) associated with anaesthesia management of ENT children in Europe. OBJECTIVE To characterise the epidemiology and incidence of respiratory SCEs during and following ENT surgery in Europe and to identify the risk factors for their occurrence. DESIGN A secondary analysis of the Anaesthesia PRactice In Children Observational Trial, a prospective...
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Maternal anaesthesia in open and fetoscopic surgery of foetal open spinal neural tube defects: A retrospective cohort study
BACKGROUND Prenatal myelomeningocele repair by open surgery can improve the neurological prognosis of children with this condition. A shift towards a fetoscopic approach seems to reduce maternal risks and improve obstetric outcomes. OBJECTIVE The aim of this study was to report on the anaesthetic management of women undergoing prenatal open or fetoscopic surgery for neural tube defects. DESIGN A retrospective cohort study. SETTING Prenatal myelomeningocele repair research group, Vall d’Hebron University Hospital, Spain. INTERVENTION Intra-uterine foetal repairs of spina bifida between 2011 and 2016 were...
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Clear fluids fasting for elective paediatric anaesthesia: The European Society of Anaesthesiology consensus statement
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 2, 2019 Category: Anesthesiology Tags: Editorial Source Type: research

European paediatric anaesthesia e-learning platform pearls and challenges
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Media review Source Type: research

Lack of consensus on the peri-operative management of patients with diabetes mellitus
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesiology residents have no significant effect on anaesthesia or procedure times
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Six-minute walk test in pre-operative evaluation of patients for upper abdominal surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: thromboprophylaxis in the obese surgical patient
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Thromboprophylaxis in the obese surgical patient
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Goal-directed therapy during transthoracic oesophageal resection does not improve outcome: Randomised controlled trial
BACKGROUND Goal-directed therapy (GDT) is expected to be of highest benefit in high-risk surgery. Therefore, GDT is recommended during oesophageal resection, which carries a high risk of postoperative complications. OBJECTIVES The aim of this study was to confirm the hypothesis that GDT during oesophageal resection improves outcome compared with standard care. DESIGN A randomised controlled study. SETTING Two Swedish university hospitals, between October 2011 and October 2015. PATIENTS Sixty-four patients scheduled for elective transthoracic oesophageal resection were randomised. Exclusion criteria included c...
Source: European Journal of Anaesthesiology - January 10, 2019 Category: Anesthesiology Tags: Monitoring Source Type: research