Significantly prolonged neuromuscular blockade after a single dose of rocuronium: The importance of monitoring
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Relationship between timing of sugammadex administration and development of laryngospasm during recovery from anaesthesia when using supraglottic devices: A randomised clinical study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Use of rocuronium and sugammadex in renal transplantation: Problems that must be considered
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

S100B protein and neuron-specific enolase as predictors of cognitive dysfunction after coronary artery bypass graft surgery: A prospective observational study
CONCLUSION: Although serum levels of S100B protein and NSE are both significantly increased postoperatively, our findings indicate that serum levels of S100B protein may be more accurate than NSE in the detection of POCD after CABG. TRIAL REGISTRATION: NCT01550159. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Neuroscience Source Type: research

Propofol, but not ketamine or midazolam, exerts neuroprotection after ischaemic injury by inhibition of Toll-like receptor 4 and nuclear factor kappa-light-chain-enhancer of activated B-cell signalling: A combined in vitro and animal study
CONCLUSION: Propofol, but neither midazolam nor ketamine, provides neuroprotection to injured neuronal cells via inhibition of TLR-4-NF-κB-dependent signalling. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Neuroscience Source Type: research

Early matrix metalloproteinase-9 concentration in the first 48 h after aneurysmal subarachnoid haemorrhage predicts delayed cerebral ischaemia: An observational study
CONCLUSION: MMP-9 concentrations in both plasma and CSF, measured within 48 h after subarachnoid haemorrhage, were highly predictive of the occurrence of delayed cerebral ischaemia within the first 2 weeks. TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT02397759. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Neuroscience Source Type: research

Effects of neoadjuvant chemo or chemoradiotherapy for oesophageal cancer on perioperative haemodynamics: A prospective cohort study within a randomised clinical trial
CONCLUSION: Neoadjuvant chemoradiotherapy for oesophageal or gastrooesophageal junction cancer seems to induce only a marginal negative effect on cardiac function compared with neoadjuvant chemotherapy. This difference did not remain when patients’ haemodynamics were challenged by surgery. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01362127. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Cardiovascular physiology Source Type: research

Predicting stroke volume and arterial pressure fluid responsiveness in liver cirrhosis patients using dynamic preload variables: A prospective study of diagnostic accuracy
The objective was to evaluate SV and arterial pressure fluid responsiveness in liver cirrhosis patients by using dynamic preload and vascular tone variables. DESIGN: A prospective study of diagnostic accuracy. SETTINGS: A single-centre trial conducted from November 2013 to April 2015. PATIENTS: Thirty-one adult patients, recipients of a living donor liver transplantat. INTERVENTION: An intraoperative fluid challenge with 10 ml kg−1 of 0.9% normal saline. MAIN OUTCOME MEASURES: PPV, SVV, cardiac index and systemic vascular resistance index were measured using the Pulse index Continuous cardiac system. The PVI...
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Cardiovascular physiology Source Type: research

Preload dependency determines the effects of phenylephrine on cardiac output in anaesthetised patients: A prospective observational study
BACKGROUND: Although phenylephrine is widely used in the operating room to control arterial pressure, its haemodynamic effects remain controversial. OBJECTIVE: We hypothesised that the effect of phenylephrine on cardiac output is affected by preload dependency. DESIGN: A prospective observational study. SETTING: Single-centre, University Hospital of Caen, France. PATIENTS: Fifty ventilated patients undergoing surgery were studied during hypotension before and after administration of phenylephrine. MAIN OUTCOME MEASURES: Cardiac index (CI), stroke volume (SV), corrected flow time, mean arterial pressure, pulse pressure...
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Cardiovascular physiology Source Type: research

Satisfaction and safety using dexmedetomidine or propofol sedation during endoscopic oesophageal procedures: A randomised controlled trial
BACKGROUND: Dexmedetomidine possesses anxiolytic and hypnotic properties without respiratory side-effects, making it theoretically an ideal sedative agent for endoscopic procedures. OBJECTIVE: We aimed to compare satisfaction and safety among outpatients receiving sedation with dexmedetomidine or propofol for endoscopic oesophageal procedures. DESIGN: A randomised controlled study. SETTING: Endoscopic intervention suite at the Academic Medical Centre in Amsterdam, Netherlands. PARTICIPANTS: Patients aged at least 18 years, and American Society of Anesthesiologists’ physical status 1 to 3. INTERVENTION: Total 63 ...
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Pharmacology Source Type: research

Effects of remifentanil on pharyngeal swallowing: A double blind randomised cross-over study in healthy volunteers
CONCLUSION: Remifentanil induced dysfunction of the pharyngeal swallowing mechanism. This may contribute to an increased risk of aspiration. TRIAL REGISTRATION: NCT01924234 (www.clinicaltrials.gov ). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Pharmacology Source Type: research

Language: another cause of publication bias
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Editorial Source Type: research

Inhaled anaesthetics and nitrous oxide: Complexities overlooked: things may not be what they seem
This review re-examines existing pharmacokinetic and pharmacodynamic concepts of inhaled anaesthetics. After showing where uptake is hidden in the classic FA/FI curve, it is argued that target-controlled delivery of inhaled agents warrants a different interpretation of the factors affecting this curve (cardiac output, ventilation and blood/gas partition coefficient). Blood/gas partition coefficients of modern agents may be less important clinically than generally assumed. The partial pressure cascade from delivered to inspired to end-expired is re-examined to better understand the effect of rebreathing during low-flow anae...
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Review Source Type: research

Graphic Anaesthesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Book review Source Type: research

Peritonsillar morphine infiltration to prevent early postoperative pain after tonsillectomy: A randomised controlled trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Effects of a single-dose preemptive pregabalin on acute and chronic pain after inguinal hernia repair with mesh under spinal anaesthesia: A randomised controlled trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Are transdermal opioids contraindicated in patients at risk of suicide?: An underappreciated problem
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The vertical obturator nerve block: A randomised controlled double-blind pilot trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Inadvertent administration of hypertonic saline during postoperative thoracic epidural patient-controlled epidural analgesia: A case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Regional haemodynamic changes after selective block of the four principal nerves in the arm: A double-blind randomised controlled study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Transcutaneous vocal cord ultrasonography after oral and maxillofacial surgery requiring intermaxillary fixation: A technical report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Acromio-axillo-suprasternal notch index: a new screening test to predict difficult laryngoscopy in obstetric patients scheduled for caesarean delivery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The efficacy of different doses of liquorice gargling for attenuating postoperative sore throat and cough after tracheal intubation
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Upper airway trauma during general anaesthesia for major surgery: incidence and trends: A retrospective study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Comparing airway topical anaesthesia techniques for awake fibreoptic intubation
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Clinical pertinence and diagnostic accuracy of an evidence-based monitoring system: Custos
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Gender difference in career advancement and job satisfaction in anaesthesia: A cross-sectional study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Impact of disruptions on anaesthetic workflow during anaesthesia induction and patient positioning: A prospective study
CONCLUSION: The study quantifies time inefficiencies affecting anaesthetic work during the preoperative phase. Work disruption wastes time and is preventable. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Education, simulation and resuscitation Source Type: research

Dispatcher-assisted compression-only cardiopulmonary resuscitation provides best quality cardiopulmonary resuscitation by laypersons: A randomised controlled single-blinded manikin trial
CONCLUSION: Best quality of CPR was achieved by DACO-CPR because of superior compression frequencies and reduced NFT. In contrast, the full dispatcher-assisted CPR with a longer initial instructing phase (initial NFT) did not result in enhanced CPR quality or an optimised compression depth. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Education, simulation and resuscitation Source Type: research

Simulation-based medical education training improves short and long-term competency in, and knowledge of central venous catheter insertion: A before and after intervention study
BACKGROUND: Multimodal educational interventions have been shown to improve short-term competency in, and knowledge of central venous catheter (CVC) insertion. OBJECTIVE: To evaluate the effectiveness of simulation-based medical education training in improving short and long-term competency in, and knowledge of CVC insertion. DESIGN: Before and after intervention study. SETTING: University Geneva Hospital, Geneva, Switzerland, between May 2008 and January 2012. PARTICIPANTS: Residents in anaesthesiology aware of the Seldinger technique for vascular puncture. INTERVENTION: Participants attended a half-day course on CVC...
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Education, simulation and resuscitation Source Type: research

Transforming the learning outcomes of anaesthesiology training into entrustable professional activities: A Delphi study
CONCLUSION: This study is a first step toward a more contemporary curriculum in competency-based postgraduate anaesthesiology training. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Education, simulation and resuscitation Source Type: research

‘Entrustable professional activities’: the way to go for competency-based curriculum?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Invited commentary Source Type: research

Don’t forget to ventilate during cardiopulmonary resuscitation with mechanical chest compression devices
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 5, 2016 Category: Anesthesiology Tags: Editorial Source Type: research

Correct positioning of central venous catheters with ECG guidance in paediatric patients
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Rare case of eyeball rupture following oculocardiac reflex during anaesthesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: Bloom's syndrome
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: rocuronium and sugammadex in the anaesthetic management of a parturient with Becker's myotonia congenita
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: primary autosomal recessive microcephaly-10 caused by a mutation in the ZNF335 gene
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Electrical stimulation of the heart 7 acupuncture site for preventing emergence agitation in children: A randomised controlled trial
CONCLUSION: Bilateral electrical stimulation of HT7 using two PNS devices significantly decreases the incidence of emergence agitation. TRIAL REGISTRATION: UMIN Clinical Trial Registry (registry number: UMIN000011704). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Effect of head position on laryngeal visualisation with the McGrath MAC videolaryngoscope in paediatric patients: A randomised controlled trial
CONCLUSION: Visualisation of the glottis and handling of the McGrath MAC video laryngoscope were significantly better when the external auditory meatus and sternal notch were aligned in the horizontal plane. TRIAL REGISTRATION: http://cris.nih.go.kridentifier:KCT0001443 . (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Short-axis/out-of-plane or long-axis/in-plane ultrasound-guided arterial cannulation in children: A randomised controlled trial
CONCLUSION: Despite the longer imaging time with the LAX approach, there was no significant difference in the total time to successful cannulation between the two techniques. The posterior wall puncture rate was lower in the LAX group than in the SAX group. TRIAL REGISTRATION: Clinicaltrials.gov (identifier: NCT02333786). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Paediatric anaesthesia Source Type: research

Intravascular volume therapy in adults: Guidelines from the Association of the Scientific Medical Societies in Germany
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Volume therapy Source Type: research

The quest for the holy volume therapy
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Invited commentary Source Type: research

The half-life of infusion fluids: An educational review
An understanding of the half-life (T1/2) of infused fluids can help prevent iatrogenic problems such as volume overload and postoperative interstitial oedema. Simulations show that a prolongation of the T1/2 for crystalloid fluid increases the plasma volume and promotes accumulation of fluid in the interstitial fluid space. The T1/2 for crystalloids is usually 20 to 40 min in conscious humans but might extend to 80 min or longer in the presence of preoperative stress, dehydration, blood loss of (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Review Source Type: research

Ethics in practice: is it futile to talk about ‘futility’?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 7, 2016 Category: Anesthesiology Tags: Editorial Source Type: research

Perioperative Medicine for the Junior Clinician
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Book review Source Type: research

Reply to: the use of advanced airway management devices in clinical practice
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

The use of advanced airway management devices in clinical practice
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Changes in intracranial pressure and cerebral blood flow during volatile anaesthesia: Fact or fiction?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research

Incidence of general anaesthesia for caesarean section in parturients from different geographic regions: 7-year retrospective study in a single European university centre
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 5, 2016 Category: Anesthesiology Tags: Correspondence Source Type: research