Effects of goal-directed crystalloid vs. colloid fluid therapy on microcirculation during free flap surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 1, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Sevoflurane sedation attenuates early cerebral oedema formation through stabilisation of the adherens junction protein beta catenin in a model of subarachnoid haemorrhage: A randomised animal study
CONCLUSION This experiment demonstrates that low-dose short-term sevoflurane sedation after SAH in vivo did not affect ICP and MAP and at the same time may attenuate early brain oedema formation, potentially by preserving adherens junctions. TRIAL REGISTRATION No 115/2014 Veterinäramt Zürich. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 1, 2020 Category: Anesthesiology Tags: Miscellaneous Source Type: research

The effectiveness of a low-dose esketamine versus an alfentanil adjunct to propofol sedation during endoscopic retrograde cholangiopancreatography: A randomised controlled multicentre trial
BACKGROUND Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most complex gastrointestinal endoscopic procedures. Currently, it is still unclear which sedation regimen best facilitates an ERCP. The N-methyl-D-aspartate receptor antagonist esketamine has anaesthetic, analgesic and sympathomimetic properties and is known to cause less cardiorespiratory depression than other sedatives. It could therefore be an ideal adjunct to propofol for deep sedation. OBJECTIVE To assess the effectiveness of esketamine versus alfentanil as an adjunct to propofol target-controlled infusion (TCI) for deep sedation duri...
Source: European Journal of Anaesthesiology - May 1, 2020 Category: Anesthesiology Tags: Miscellaneous Source Type: research

Simulated patient-based teaching of medical students improves pre-anaesthetic assessment: A rater-blinded randomised controlled trial
CONCLUSION The current single teaching encounter with a trained layperson acting as a simulated patient improved medical student performances in their pre-anaesthetic clinical assessment of surgical patients. This might be a suitable alternative to reduce the teaching burden for busy and costly clinicians. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 1, 2020 Category: Anesthesiology Tags: Miscellaneous Source Type: research

Intra-operative norepinephrine administration and cancer-related outcomes following radical cystectomy for bladder cancer: A cohort study
CONCLUSION Continuous administration of more than 2 μg kg BW−1 h−1 norepinephrine was associated with a slightly increased hazard ratio for tumour recurrence if adjusted for intra-operative variables and year of surgery. This observation could reflect a low potential pro-oncogenic effect of norepinephrine during the intra-operative period. TRIAL REGISTRATION Not applicable. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 1, 2020 Category: Anesthesiology Tags: Miscellaneous Source Type: research

European Society of Anaesthesiology guidelines on peri-operative use of ultrasound-guided for vascular access (PERSEUS vascular access)
Ultrasound for diagnostic and procedural purposes is becoming a standard in daily clinical practice including anaesthesiology and peri-operative medicine. The project of European Society of Anaesthesiology (ESA) Task Force for the development of clinical guidelines on the PERioperative uSE of Ultra-Sound (PERSEUS) project has focused on the use of ultrasound in two areas that account for the majority of procedures performed routinely in the operating room: vascular access and regional anaesthesia. Given the extensive literature available in these two areas, this paper will focus on the use of ultrasound-guidance for vascul...
Source: European Journal of Anaesthesiology - May 1, 2020 Category: Anesthesiology Tags: Guidelines Source Type: research

Ultrasound-guided vascular access
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 1, 2020 Category: Anesthesiology Tags: Invited commentary Source Type: research

Use of tracheal ultrasound combined with clinical parameters to select left double-lumen tube size. A prospective observational study: Erratum
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Erratum Source Type: research

Principles of Geriatric Critical Care
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Book review Source Type: research

Severe cerebrospinal fluid-cutaneous fistula treated by an epidural tetrastarch patch: A case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Sedation with remifentanil or propofol for flexible bronchoscopy: A randomised controlled trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Prophylactic insertion of a transtracheal catheter for anticipated difficult airway management: A retrospective analysis
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

A single-dose of stellate ganglion block for the prevention of postoperative dysrhythmias in patients undergoing thoracoscopic surgery for cancer: A randomised controlled double-blind trial
CONCLUSION A pre-operative SGB effectively prevented the occurrence of postoperative supraventricular tachycardias and improves the objective sleep quality in patients undergoing thoracic surgery for cancer. TRIAL REGISTRATION NUMBER ChiCTR-1900023064. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

The effect of ropivacaine concentration on common peroneal nerve block duration using a fixed dose: A randomised, double-blind trial in healthy volunteers
CONCLUSION In contrast to our hypothesis, we found no changes in mean sensory nerve block duration. However, local anaesthetic dilution resulted in reduced motor block duration. TRIAL REGISTRATION ClinicalTrials.gov, NCT03326609. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research

Norepinephrine for the prevention of spinal-induced hypotension during caesarean delivery under combined spinal–epidural anaesthesia: Randomised, double-blind, dose-finding study
CONCLUSION The ED50, ED80 and ED95 were 0.029, 0.068 and 0.105 μg kg−1 min−1 respectively. A 0.07 μg kg−1 min−1 norepinephrine infusion may be optimum for preventing postspinal hypotension after intrathecal injection of 10 mg bupivacaine combined with 5 μg sufentanil. TRIAL REGISTRATION Chinese Clinical Trial Registry (identifier: ChiCTR-TRC-1800014614). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Obstetric anaesthesia Source Type: research

An ultrasound assessment of gastric emptying following tea with milk in pregnancy: A randomised controlled trial
CONCLUSION The change of gastric antrum CSA after 250 ml of tea with milk is similar to a corresponding volume of water in fasted pregnant patients. This study could help inform future peri-operative fasting guidelines regarding the use of a modest volume of milk with clear fluids. TRIAL REGISTRY NUMBER NCT 03694509 ClinicalTrials.gov. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Obstetric anaesthesia Source Type: research

Video-assisted cardiopulmonary resuscitation via smartphone improves quality of resuscitation: A randomised controlled simulation trial
This study was conducted in the Skills Lab of the University Hospital of Cologne. PARTICIPANTS One hundred and fifty healthy adult volunteers. INTERVENTION The participants received a smartphone to call emergency services, with Emergency Eye video-call in V-CPR group, and normal telephone functionality in the other groups. T-CPR and V-CPR groups received standardised CPR assistance via phone. MAIN OUTCOME MEASURES Our primary endpoint was resuscitation quality, quantified by compression frequency and depth, and correct hand position. RESULTS Mean compression frequency of V-CPR group was 106.4 ± 11.7...
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Resuscitation Source Type: research

High-quality chest compressions are possible during intra-hospital transport, but depend on provider position: A manikin study
BACKGROUND Treatment of reversible causes of cardiac arrest often requires intrahospital transportation during ongoing resuscitation. But high-quality chest compression with minimal interruption is the most essential prerequisite for an optimal outcome after cardiac resuscitation. OBJECTIVE We aimed to evaluate chest compression quality according to the provider position during intrahospital transportation. DESIGN Manikin observational study. SETTING German Tertiary Care Hospital. PARTICIPANTS A total of 20 paramedics (eight female, 12 male); average professional experience 4.8 ± 3.1 years since th...
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Resuscitation Source Type: research

Extracorporeal cardiopulmonary resuscitation at the emergency department: A retrospective patient selection evaluation
BACKGROUND There is an increasing use of extracorporeal life support in refractory cardiac arrest. Recent studies highlighted the importance of an early and accurate patient selection for this invasive procedure. OBJECTIVES The aim of this study was to retrospectively validate a six-criteria-screening-checklist (witnessed collapse, bystander-cardiopulmonary resuscitation/first medical contact (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Resuscitation Source Type: research

Noninvasive respiratory support in the hypoxaemic peri-operative/periprocedural patient: A joint ESA/ESICM guideline
Hypoxaemia is a potential life-threatening yet common complication in the peri-operative and periprocedural patient (e.g. during an invasive procedure with risk of deterioration of gas exchange, such as bronchoscopy). The European Society of Anaesthesiology (ESA) and the European Society of Intensive Care Medicine (ESICM) have developed guidelines for the use of noninvasive respiratory support techniques in the hypoxaemic patient in the peri-operative and periprocedural period. The panel outlined five clinical questions regarding treatment with noninvasive respiratory support techniques [conventional oxygen therapy (COT), ...
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Guidelines Source Type: research

Prevention of postoperative pulmonary complications in the hypoxaemic patient – gathering the evidence for noninvasive respiratory support
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Invited Commentary Source Type: research

Prehabilitation: The next challenge for anaesthesia teams
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 6, 2020 Category: Anesthesiology Tags: Editorial Source Type: research

Oxford Textbook of Anaesthesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Book review Source Type: research

Reply to: functional recovery after knee arthroplasty with regional analgesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Functional recovery after knee arthroplasty with regional analgesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Improving perisurgical pain control: Ten Mistakes to be avoided
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Modulation of pain areas by greater occipital nerve block in chronic daily headache
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Asystole triggered by the trigeminocardiac reflex following posttetanic count stimulation of the facial nerve: A case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Data-science-based subgroup analysis of persistent pain during 3 years after breast cancer surgery: A prospective cohort study
CONCLUSION In the majority of patients, pain after breast cancer surgery decreased rapidly and disappeared or the intensity decreased over 3 years. However, in about a tenth of patients, moderate-to-severe pain tended to increase during the 3-year follow-up. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Pain Source Type: research

Synergistic effect of the association between lidocaine and magnesium sulfate on peri-operative pain after mastectomy: A randomised, double-blind trial
BACKGROUND Recently, the use of venous adjuvants, such as lidocaine and magnesium sulfate, has been gaining ground in multimodal analgesia. However, no study has evaluated the impact a combination of the two drugs. OBJECTIVES To evaluate the efficacy of venous adjuvants in reducing opioid consumption and pain scores after mastectomy. DESIGN Randomised, double-blind, parallel-group, noninferiority clinical trial with a 1 : 1 : 1 : 1 allocation ratio. SETTING Hospital de Base do Distrito Federal, Brasilia, Federal District, Brazil from November 2014 to December 2017. PATIENTS One-hundred and ninety-...
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Pain Source Type: research

The effect of intravenous magnesium on postoperative morphine consumption in noncardiac surgery: A systematic review and meta-analysis with trial sequential analysis
BACKGROUND Several studies suggest that systemic magnesium reduces postoperative opioid consumption and the intensity of pain, but others report conflicting results. The efficacy and safety profile of intravenous magnesium in noncardiac surgery remain uncertain. OBJECTIVES The aim of this review was to investigate the effect of intravenous magnesium on the consumption of postoperative morphine in the first 24 h in adults undergoing noncardiac surgery. DESIGN Systematic review and meta-analysis with trial sequential analysis. DATA SOURCES MEDLINE, EMBASE, CENTRAL from their inception until January 2019. ELIGIB...
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Pain Source Type: research

Spontaneous recovery of neuromuscular blockade is an independent risk factor for postoperative pulmonary complications after abdominal surgery: A secondary analysis
CONCLUSION Spontaneous recovery of neuromuscular blockade was an independent risk factor for PPCs in patients with intermediate-to-high risk, undergoing abdominal surgery. We suggest this factor should be included in future studies on PPCs. TRIAL REGISTRATION clinicaltrials.gov identifier: NCT02158923. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Neuromuscular blockade Source Type: research

Postoperative residual neuromuscular blockade after reversal based on a qualitative peripheral nerve stimulator response: A randomised controlled trial
We examined and compared the incidence of residual neuromuscular blockade when the recommended dose of neostigmine or sugammadex was administered according to a qualitative nerve stimulator response. DESIGN A randomised controlled trial. SETTING A tertiary care hospital in South Korea from September 2017 to November 2017. PATIENTS Eighty patients aged between 18 and 69 years were included in this study. All were patients scheduled to undergo elective laparoscopic cholecystectomy and who had an American Society of Anaesthesiologists physical status of one or two were eligible. INTERVENTIONS Patients were allocat...
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Neuromuscular blockade Source Type: research

Deep neuromuscular blockade during spinal surgery reduces intra-operative blood loss: A randomised clinical trial
BACKGROUND Spinal surgery is usually performed in the prone position using a posterior approach. However, the prone position may cause venous engorgement in the back and thus increase surgical bleeding with interruption of surgery. The prone position also affects cardiac output since large vessels are compressed decreasing venous return to the heart. OBJECTIVE We hypothesised that deep neuromuscular blockade would be associated with less surgical bleeding during spinal surgery in the prone position. DESIGN Randomised, single blinded trial. SETTING University teaching hospital. PARTICIPANTS Eighty-eight patien...
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Neuromuscular blockade Source Type: research

Evaluation of autologous retransfusion from a closed suction drainage system for patient blood management in elective total hip and knee replacement: A two cohort study
CONCLUSION Our study questions the effectiveness of postoperative autotransfusion as part of a patient blood management programme. In addition, the obvious signs of inflammatory reactions and coagulation activation raise safety concerns. TRIAL REGISTRATION The cohort study was not registered in a trial registry. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Blood management Source Type: research

Fibrinolytic shutdown diagnosed with rotational thromboelastometry represents a moderate form of coagulopathy associated with transfusion requirement and mortality: A retrospective analysis
CONCLUSION The results of the current study suggest that shutdown, which is associated with injury severity and mortality, probably reflects a moderate form of coagulopathy and fibrinolysis rather than a hypercoagulopathy. Therefore, the observation of shutdown fibrinolysis on thromboelastography/rotational thromboelastometry should not lead to withholding but rather to the administration of TXA. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Blood management Source Type: research

Heparin sensitivity and postoperative blood loss in patients undergoing cardiac surgery with cardiopulmonary bypass
BACKGROUND Heparin-associated coagulation disorder is an important factor related to postoperative bleeding in patients undergoing cardiac surgery with cardiopulmonary bypass. Currently, the relationship between heparin sensitivity and postoperative bleeding is unknown. OBJECTIVE To investigate the relationship between individual heparin sensitivity and postoperative blood loss in patients undergoing cardiac surgery. DESIGN Prospective controlled study. SETTING Tertiary teaching hospital, Urumqi, Xinjiang, PR China. The study was conducted from January 2016 to August 2018. PATIENTS A total of 195 adult patien...
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Blood management Source Type: research

Is goal-directed haemodynamic therapy dead?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - February 8, 2020 Category: Anesthesiology Tags: Editorial Source Type: research

Anaesthesiology: a problem-based learning approach
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Book review Source Type: research

Tips and tricks: Supraglottic airway device insertion using a tongue depressor
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Tips and tricks: Real-time ultrasound-guided left supraclavicular approach as a rapidly applied alternative venous access in paediatric difficult peripheral vein cases
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Effect of different manoeuvres on internal jugular vein cross-sectional area in obese and normal-weight patients
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Major complications after scheduled craniotomy: A justification for systematic postoperative intensive care admission?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Secure insertion of the i-gel supraglottic airway device in children: A cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Lung sliding sign to detect endobronchial intubation in children: An observational feasibility trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: A child with incontinentia pigmenti
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: A 2-year-old with neuronal ceroid lipofuscinosis
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Anaesthesia and orphan disease: Tracheal reconstruction in two children with Morquio disease
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Dexmedetomidine versus propofol sedation in reducing delirium among older adults in the ICU: A systematic review and meta-analysis
CONCLUSION Compared with propofol, dexmedetomidine sedation in the ICU is associated with lower delirium incidence among older adults with no significant increase in adverse events. In older adult ICU patients at risk of developing delirium, sedation with dexmedetomidine should be considered. Further research is warranted to elucidate and explain the mechanisms underlying this process, and to confirm our findings with large, multicentre trials. TRIAL REGISTRATION The study protocol has been registered in PROSPERO (CRD42018099339). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Intensive care medicine Source Type: research

Nonadherence to antibiotic guidelines in patients admitted to ICU with sepsis is associated with increased mortality: A registry-based, retrospective cohort study
BACKGROUND Early appropriate antibiotic therapy is an important component of the Surviving Sepsis Guidelines bundles that are associated with decreased in-hospital mortality. National antibiotic guidelines for the treatment of sepsis in Sweden have been available since 2008. Compliance with these guidelines is largely unknown, and whether it translates to improved patient outcome has not been studied. OBJECTIVE To assess mortality and its relationship to compliance with Swedish antibiotic guidelines. A secondary aim was to assess the effect of timing of antibiotic administration and mortality. DESIGN A registry-bas...
Source: European Journal of Anaesthesiology - January 10, 2020 Category: Anesthesiology Tags: Intensive care medicine Source Type: research