Transanal endoscopic microsurgical submucosal dissection (TEM-ESD) for recurrent rectal adenomas
Conclusion
TEM-ESD is a feasible therapeutic option for the resection of recurrent rectal adenomas, offering short operating times as well as high en bloc resection and low recurrence rates. (Source: Digestive Diseases)
Source: Digestive Diseases - February 24, 2022 Category: Gastroenterology Source Type: research
Performance of the Liver Maximum Function Capacity Test, Fibrinogen, and Transient Elastography in Patients with Acute Liver Injury
Conclusion: Decision-making in ALF remains challenging. LiMAx and fibrinogen might predict the prognosis in patients with nonacetaminophen-induced ALF and in combination could be feasible tools to decide if LT is necessary. (Source: Digestive Diseases)
Source: Digestive Diseases - February 22, 2022 Category: Gastroenterology Source Type: research
Performance of the LiMAx test, fibrinogen, and transient elastography in patients with acute liver injury
Conclusion
Decision-making in ALF remains challenging. LiMAx and fibrinogen might predict the prognosis in patients with non-acetaminophen-induced ALF and in combination could be feasible tools to decide if LT is necessary. (Source: Digestive Diseases)
Source: Digestive Diseases - February 22, 2022 Category: Gastroenterology Source Type: research
Linked color imaging and blue laser imaging for the diagnosis of superficial non-ampullary duodenal epithelial tumors
This study aimed to evaluate endoscopic findings using linked color imaging (LCI) and blue laser imaging (BLI) and to determine a diagnostic predictor for duodenal adenocarcinomas.
Methods: All consecutive patients who underwent endoscopic resection for superficial non-ampullary duodenal epithelial tumors (SNADETs) between October 2012 and June 2019 were enrolled in this study. Two highly experienced endoscopists investigated six morphological findings using both white light imaging (WLI) and LCI and three magnifying endoscopic findings using magnifying BLI (M-BLI).
Results: A total of 90 patients with 110 SNADETs, inclu...
Source: Digestive Diseases - February 17, 2022 Category: Gastroenterology Source Type: research
Distance matters: Correlation of HCC nodule distance to overall survival
Conclusion: Thus, not only the size of multiple HCC lesions but also their distance is important for the prognosis of patients with HCC. This may be of particular interest in patients with two nodules and BCLC B and C stages for the selection of therapeutic modalities and/or procedures. (Source: Digestive Diseases)
Source: Digestive Diseases - February 16, 2022 Category: Gastroenterology Source Type: research
Comparison of Mortality Prediction Scores in Intermediate-Care Patients with Liver Cirrhosis at a German university transplant Center; a prospective study
Conclusion: 90-day-mortality risk prediction of the SAPS 3 and CLIF-C ACLF was accurrate in our cohort of patients with liver cirrhosis admitted to ImCU. A particular challenge remains the mortality prediction in patients with ACLF requiring ImCU-level care; here, further developments are needed to generate scores with acceptable predictive performances. (Source: Digestive Diseases)
Source: Digestive Diseases - February 16, 2022 Category: Gastroenterology Source Type: research
Biliary Sphincterotomy Alone versus Biliary Stent with or without Biliary Sphincterotomy for the Management of Post-Cholecystectomy Bile Leak: A Systematic Review and Meta-Analysis
Conclusions: Biliary stent ± BS is more effective in endoscopic management of PCBL compared to BS alone. This may be related to inter-endoscopist variation in completeness of sphincterotomy and post-sphincterotomy edema, which can influence the preferential trans-papillary flow of bile. (Source: Digestive Diseases)
Source: Digestive Diseases - February 7, 2022 Category: Gastroenterology Source Type: research
Biliary sphincterotomy alone vs biliary stent with or without biliary sphincterotomy for the management of post-cholecystectomy bile leak: a sytematic review and meta-analysis
BACKGROUND: Endoscopic therapy with ERCP is considered the first line treatment in the management of post-cholecystectomy bile leak (PCBL). Currently there is no consensus on the most effective endoscopic intervention for PCBL. Hence, we performed a systematic review and meta-analysis to compare the effectiveness and safety of the two interventional groups (biliary sphincterotomy [BS] alone vs biliary stent ± BS) in management of PCBL.
METHODS: We conducted a comprehensive search of multiple electronic databases and conference proceedings (from inception through January 2021). The primary outcome was to compare the pool...
Source: Digestive Diseases - February 7, 2022 Category: Gastroenterology Source Type: research
Transjugular intrahepatic portosystemic shunt for portal vein cavernous transformation: a systematic review and single-arm meta-analysis
Conclusions: TIPS is feasible and safe in patients with PVCT and PVCT should not be considered an absolute contraindication to TIPS. (Source: Digestive Diseases)
Source: Digestive Diseases - February 7, 2022 Category: Gastroenterology Source Type: research
Primary Nonfunction and Early Allograft Dysfunction after Liver Transplantation
This article pre sents the current approach to diagnosis, prediction, and management of EAD and PNF.Key Messages: Different pharmacological interventions may be considered to improve graft function after liver transplantation. Machine perfusion seems to be the most effective method at the moment. (Source: Digestive Diseases)
Source: Digestive Diseases - February 3, 2022 Category: Gastroenterology Source Type: research
Primary non-function and early allograft dysfunction after liver transplantation
This article presents current approach to diagnosis, prediction and management of EAD and PNF. Key messages: Different pharmacological interventions may be considered to improve graft function after liver transplantation. Machine perfusion seems to be the most effective method at the moment. (Source: Digestive Diseases)
Source: Digestive Diseases - February 3, 2022 Category: Gastroenterology Source Type: research
Hepatitis B reactivation in patients treated with direct-acting antivirals for Hepatitis C
Conclusion:Patients with HBV/HCV co-infection have a high risk of HBVr after DAA treatment and should receive antiviral prophylaxis. Patients with resolved infection have a low risk of HBVr and can be monitored by serial ALT measurements. (Source: Digestive Diseases)
Source: Digestive Diseases - February 2, 2022 Category: Gastroenterology Source Type: research
Factors related to delayed adverse events of endoscopic submucosal dissection in the duodenum
Conclusions: Complete ulcer suture was related to decreased risk of delayed adverse events after D-ESD. From the bleeding period and healing process of D-ESD ulcers, the minimum required length of PPI may be three weeks after D-ESD. (Source: Digestive Diseases)
Source: Digestive Diseases - February 2, 2022 Category: Gastroenterology Source Type: research
The Efficacy of Biofeedback Therapy in Patients with Solitary Rectal Ulcer and Dyssynergic Defecation
Conclusions: SRU patients with DD are typically unresponsive medical treatments. Ameliorating anorectal dyssynergia should be the priority of treatment in these patients. BFT is an effective treatment for DD. BFT enhances the healing of ulcers in patients with SRU by restoring coordination of the pelvic floor. (Source: Digestive Diseases)
Source: Digestive Diseases - January 31, 2022 Category: Gastroenterology Source Type: research
Real-world effectiveness of piperacillin/tazobactam with and without linezolid for spontaneous bacterial peritonitis
Conclusion: In this retrospective analysis, empirical TZP+LZD combination therapy for SBP was associated with fewer treatment failures without impact on short-term survival. (Source: Digestive Diseases)
Source: Digestive Diseases - January 31, 2022 Category: Gastroenterology Source Type: research
