Development of a multinational clinical practice guideline: a practical structured procedure
We describe a structured guideline procedure that can be adjusted to the requirements of other multinational guidelines.
Methods: Clinical scientists with experience of organizing and contributing to guidelines initiated this guideline project. A balance between scientific evidence and clinical experience was achieved by involving European specialist societies and physicians from 18 European countries. For persons contributing to the guideline process, different levels of involvement were defined. The tasks were assigned to different groups of persons, which formed scientific institutions.
Results: We describe organizati...
Source: Digestive Diseases - August 19, 2020 Category: Gastroenterology Source Type: research
Validity of International Classification of Diseases, 10th Revision, Codes for Cirrhosis
Conclusion:
Individual ICD-10 codes are suboptimal for identifying patients with cirrhosis in the general patient population. We recommend conditioning ICD-10 code searches with a chronic liver disease diagnosis code and/or combining diagnostic codes to maximize performance. (Source: Digestive Diseases)
Source: Digestive Diseases - August 18, 2020 Category: Gastroenterology Source Type: research
Combination of a probiotic and an antispasmodic increases quality of life and reduces symptoms in patients with irritable bowel syndrome: a pilot study
Conclusion: The results are consistent with previous studies on the use of the i3.1 probiotic formulation for the management of symptoms in IBS patients, and the addition of an antispasmodic improves its observed effects. (Source: Digestive Diseases)
Source: Digestive Diseases - August 17, 2020 Category: Gastroenterology Source Type: research
Mild versus Severe Liver Injury in SARS-CoV-2 Infection
Conclusion: Mild liver injury was not associated with worse outcome in our cohort, and the pattern of liver injury did not fit well to the theory of SARS-CoV-2 directly causing liver impairment. Instead, severe liver injury in our cohort was associated multiple-organ failure and acute vascular events. (Source: Digestive Diseases)
Source: Digestive Diseases - August 9, 2020 Category: Gastroenterology Source Type: research
Mild vs severe liver injury in SARS-CoV-2 infection
Conclusion: Mild liver injury was not associated with worse outcome in our cohort and the pattern of liver injury did not fit well to the theory of SARS-CoV-2 directly causing liver impairment. Instead, severe liver injury in our cohort was associated multiple-organ failure and acute vascular events. (Source: Digestive Diseases)
Source: Digestive Diseases - August 9, 2020 Category: Gastroenterology Source Type: research
