Nuclear Imaging Modalities in the Diagnosis and Management of Thyroid Cancer
Conclusion: Nuclear imaging plays an important role in the diagnosis, staging, and management of thyroid cancer. The use of radioiodine imaging, thyroglobulin imaging, FDG imaging, and somatostatin receptor imaging are all valuable tools in the evaluation of thyroid cancer. With further research and development, nuclear imaging techniques have the potential to improve the diagnosis and management of thyroid cancer and other endocrine malignancies.PMID:37724677 | DOI:10.2174/1566524023666230915103723 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 19, 2023 Category: Molecular Biology Authors: Namit Kant Singh Neemu Hage Balaji Ramamourthy Sushmitha Nagaraju Krishna Medha Kappagantu Source Type: research
Attenuation of NLRP3 Inflammasome by Cigarette Smoke is Correlated with Decreased Defense Response of Oral Epithelial Cells to Candida albicans
CONCLUSION: Our results suggested that in oral epithelial cells, the NLRP3 inflammasome might be one of the target pathways by which CSE attenuates innate immunity and leads to oral disorders.PMID:37723958 | DOI:10.2174/1566524023666230612143038 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 19, 2023 Category: Molecular Biology Authors: Fan Huang Ruiqi Xie Ruowei Li Liu Liu Maomao Zhao Qiong Wang Weida Liu Pei Ye Wenmei Wang Xiang Wang Source Type: research
Nuclear Imaging Modalities in the Diagnosis and Management of Thyroid Cancer
Conclusion: Nuclear imaging plays an important role in the diagnosis, staging, and management of thyroid cancer. The use of radioiodine imaging, thyroglobulin imaging, FDG imaging, and somatostatin receptor imaging are all valuable tools in the evaluation of thyroid cancer. With further research and development, nuclear imaging techniques have the potential to improve the diagnosis and management of thyroid cancer and other endocrine malignancies.PMID:37724677 | DOI:10.2174/1566524023666230915103723 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 19, 2023 Category: Molecular Biology Authors: Namit Kant Singh Neemu Hage Balaji Ramamourthy Sushmitha Nagaraju Krishna Medha Kappagantu Source Type: research
Attenuation of NLRP3 Inflammasome by Cigarette Smoke is Correlated with Decreased Defense Response of Oral Epithelial Cells to Candida albicans
CONCLUSION: Our results suggested that in oral epithelial cells, the NLRP3 inflammasome might be one of the target pathways by which CSE attenuates innate immunity and leads to oral disorders.PMID:37723958 | DOI:10.2174/1566524023666230612143038 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 19, 2023 Category: Molecular Biology Authors: Fan Huang Ruiqi Xie Ruowei Li Liu Liu Maomao Zhao Qiong Wang Weida Liu Pei Ye Wenmei Wang Xiang Wang Source Type: research
The Association between Circulating Adipocytokine Omentin Levels and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis
CONCLUSION: Additional well-designed studies with more sample sizes are essential to clarify the potential role of Omentin as a risk marker of NAFLD.PMID:37711002 | DOI:10.2174/1566524023666230913105910 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Rozita Khodashahi Mohsen Aliakbarian Gordon A Ferns Mohammad-Hassan Arjmand Source Type: research
CoCl2-mimicked hypoxia induces the assembly of stress granules in trophoblast cells via eIF2 α phosphorylation-dependent and -independent pathways
CONCLUSION: Mechanistically, both heme-regulated inhibitors (HRI) mediated eukaryotic translation initiation factor (eIF)2α phosphorylation pathway and 4E binding protein 1 (4EBP1) pathway are involved in SG formation under the stress of CoCl2-mimicked hypoxia. Hypoxia-induced SGs in trophoblast cells might contribute to the etiology of PE.PMID:37711098 | DOI:10.2174/1566524023666230913111300 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Chunling Ma Qiulan Lv Liang Ma Baoxiang Xing Yan Li Zhiyuan Li Source Type: research
Emerging Role of Ferroptosis in Breast Cancer: Characteristics, Therapy, and Translational Implications for the Present and Future
We present a fundamental analysis of the actual understanding of molecular mechanisms along with regulatory networks associated with ferroptosis, expected physiological functions in growth concealment, ferroptosis-associated differentially expressed genes, treatment targeting potential, and recent advances in the development of therapeutic strategies in this review.PMID:37711099 | DOI:10.2174/1566524023666230913105735 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research
The Association between Circulating Adipocytokine Omentin Levels and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis
CONCLUSION: Additional well-designed studies with more sample sizes are essential to clarify the potential role of Omentin as a risk marker of NAFLD.PMID:37711002 | DOI:10.2174/1566524023666230913105910 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Rozita Khodashahi Mohsen Aliakbarian Gordon A Ferns Mohammad-Hassan Arjmand Source Type: research
CoCl2-mimicked hypoxia induces the assembly of stress granules in trophoblast cells via eIF2 α phosphorylation-dependent and -independent pathways
CONCLUSION: Mechanistically, both heme-regulated inhibitors (HRI) mediated eukaryotic translation initiation factor (eIF)2α phosphorylation pathway and 4E binding protein 1 (4EBP1) pathway are involved in SG formation under the stress of CoCl2-mimicked hypoxia. Hypoxia-induced SGs in trophoblast cells might contribute to the etiology of PE.PMID:37711098 | DOI:10.2174/1566524023666230913111300 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Chunling Ma Qiulan Lv Liang Ma Baoxiang Xing Yan Li Zhiyuan Li Source Type: research
Emerging Role of Ferroptosis in Breast Cancer: Characteristics, Therapy, and Translational Implications for the Present and Future
We present a fundamental analysis of the actual understanding of molecular mechanisms along with regulatory networks associated with ferroptosis, expected physiological functions in growth concealment, ferroptosis-associated differentially expressed genes, treatment targeting potential, and recent advances in the development of therapeutic strategies in this review.PMID:37711099 | DOI:10.2174/1566524023666230913105735 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research
The Association between Circulating Adipocytokine Omentin Levels and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis
CONCLUSION: Additional well-designed studies with more sample sizes are essential to clarify the potential role of Omentin as a risk marker of NAFLD.PMID:37711002 | DOI:10.2174/1566524023666230913105910 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Rozita Khodashahi Mohsen Aliakbarian Gordon A Ferns Mohammad-Hassan Arjmand Source Type: research
CoCl2-mimicked hypoxia induces the assembly of stress granules in trophoblast cells via eIF2 α phosphorylation-dependent and -independent pathways
CONCLUSION: Mechanistically, both heme-regulated inhibitors (HRI) mediated eukaryotic translation initiation factor (eIF)2α phosphorylation pathway and 4E binding protein 1 (4EBP1) pathway are involved in SG formation under the stress of CoCl2-mimicked hypoxia. Hypoxia-induced SGs in trophoblast cells might contribute to the etiology of PE.PMID:37711098 | DOI:10.2174/1566524023666230913111300 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Chunling Ma Qiulan Lv Liang Ma Baoxiang Xing Yan Li Zhiyuan Li Source Type: research
Emerging Role of Ferroptosis in Breast Cancer: Characteristics, Therapy, and Translational Implications for the Present and Future
We present a fundamental analysis of the actual understanding of molecular mechanisms along with regulatory networks associated with ferroptosis, expected physiological functions in growth concealment, ferroptosis-associated differentially expressed genes, treatment targeting potential, and recent advances in the development of therapeutic strategies in this review.PMID:37711099 | DOI:10.2174/1566524023666230913105735 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research
Neurodegenerative disease: New hopes and perspectives
Curr Mol Med. 2023 Sep 7. doi: 10.2174/1566524023666230907093451. Online ahead of print.ABSTRACTAlzheimer's disease, Parkinson's disease, Amyotrophic lateral sclerosis, Huntington's disease, and Friedrich ataxia are all incurable neurodegenerative diseases defined by the continuous progressive loss of distinct neuronal subtypes. Despite their rising prevalence among the world's ageing population, fewer advances have been made in the concurrent massive efforts to develop newer drugs. Recently, there has been a shift in research focus towards the discovery of new therapeutic agents for neurodegenerative diseases. In this rev...
Source: Current Molecular Medicine - September 11, 2023 Category: Molecular Biology Authors: Mohammad Aadil Bhat Suneela Dhaneshwar Source Type: research
Pharmacological Potential of Bioactive Peptides for the Treatment of Diseases Associated with Alzheimer's and Brain Disorders
Curr Mol Med. 2023 Sep 7. doi: 10.2174/1566524023666230907115753. Online ahead of print.ABSTRACTBioactive peptides are a promising class of therapeutics for the treatment of diseases associated with Alzheimer's and brain disorders. These peptides are derived from naturally occurring proteins and have been shown to possess a variety of beneficial properties. They may modulate neurotransmitter systems, reduce inflammation, and improve cognitive performance. In addition, bioactive peptides have the potential to target specific molecular pathways involved in the pathogenesis of Alzheimer's and brain disorders. For example, pep...
Source: Current Molecular Medicine - September 11, 2023 Category: Molecular Biology Authors: Jeetendra Kumar Gupta Kuldeep Singh Source Type: research
