Toll-like Receptor 4 Signaling Mediates Gastritis and Gastric Cancer
This study aims to investigate the contribution of TLR4 to the inflammatory response in gastric diseases and the relation between TLR4 and H. pylori, TLR4 gene polymorphisms, and how TLR4 affects gastric diseases' possible pathways to provide further insight for future prevention and clinical treatment strategies.PMID:38204278 | DOI:10.2174/0115665240276139231206071742 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 11, 2024 Category: Molecular Biology Authors: Zepeng Zhang Ju Liu Yi Wang Lei Zhang Tong Zhou Yu Huang Tongtong Zhu Source Type: research
Dysregulated Long Non-coding RNAs in Myasthenia Gravis- A Mini-Review
Curr Mol Med. 2024 Jan 8. doi: 10.2174/0115665240281531231228051037. Online ahead of print.ABSTRACTMyasthenia gravis (MG) is an acquired autoimmune disease that is mediated by humoral immunity, supplemented by cellular immunity, along with participation of the complement system. The pathogenesis of MG is complex; although autoimmune dysfunction is clearly implicated, the specific mechanism remains unclear. Long non-coding RNAs (lncRNAs) are a class of non-coding RNA molecules with lengths greater than 200 nucleotides, with increasing evidence of their rich biological functions and high-level structure conservation. LncRNAs...
Source: Current Molecular Medicine - January 9, 2024 Category: Molecular Biology Authors: Liying Sun Xuhui Ye Linlin Wang Junping Yu Yan Wu Yun Hua Lihua Dai Source Type: research
Dysregulated Long Non-coding RNAs in Myasthenia Gravis- A Mini-Review
Curr Mol Med. 2024 Jan 8. doi: 10.2174/0115665240281531231228051037. Online ahead of print.ABSTRACTMyasthenia gravis (MG) is an acquired autoimmune disease that is mediated by humoral immunity, supplemented by cellular immunity, along with participation of the complement system. The pathogenesis of MG is complex; although autoimmune dysfunction is clearly implicated, the specific mechanism remains unclear. Long non-coding RNAs (lncRNAs) are a class of non-coding RNA molecules with lengths greater than 200 nucleotides, with increasing evidence of their rich biological functions and high-level structure conservation. LncRNAs...
Source: Current Molecular Medicine - January 9, 2024 Category: Molecular Biology Authors: Liying Sun Xuhui Ye Linlin Wang Junping Yu Yan Wu Yun Hua Lihua Dai Source Type: research
ADGRL4 Promotes Cell Growth, Aggressiveness, EMT, and Angiogenesis in Neuroblastoma via Activation of ERK/STAT3 Pathway
CONCLUSION: To conclude, the downregulation of ADGRL4 may inhibit cell growth, aggressiveness, EMT, and angiogenesis in NB by inactivating the ERK/STAT3 signaling pathway.PMID:38178660 | DOI:10.2174/0115665240254765231117122210 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Geng Geng Lei Zhang Ying Yu Xingqing Guo Qinghao Li Ming Ming Source Type: research
A Mechanism Study on the Antioxidant Pathway of Keap1-Nrf2-ARE Inhibiting Ferroptosis in Dopaminergic Neurons
CONCLUSION: Based on the transfection of P62 plasmid, it was found that P62 plasmid can inhibit the lipid peroxidation of iron death in dopaminergic nerve cells by activating the Nrf2 signaling pathway, thus playing a protective role in dopaminergic nerve cells.PMID:38178661 | DOI:10.2174/0115665240266555231120044938 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Yani Yao Peishan Li Sen Jiang Xinling Meng Hua Gao Xinling Yang Source Type: research
TPD52 is a Potential Prognostic Biomarker and Correlated with Immune Infiltration: A Pan-cancer Analysis
CONCLUSION: The TPD52 gene may be important for human cancer treatment.PMID:38178662 | DOI:10.2174/0115665240260252230919054858 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Lu Miao Li Jing Buze Chen Tian Zeng Youguo Chen Source Type: research
ADGRL4 Promotes Cell Growth, Aggressiveness, EMT, and Angiogenesis in Neuroblastoma via Activation of ERK/STAT3 Pathway
CONCLUSION: To conclude, the downregulation of ADGRL4 may inhibit cell growth, aggressiveness, EMT, and angiogenesis in NB by inactivating the ERK/STAT3 signaling pathway.PMID:38178660 | DOI:10.2174/0115665240254765231117122210 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Geng Geng Lei Zhang Ying Yu Xingqing Guo Qinghao Li Ming Ming Source Type: research
A Mechanism Study on the Antioxidant Pathway of Keap1-Nrf2-ARE Inhibiting Ferroptosis in Dopaminergic Neurons
CONCLUSION: Based on the transfection of P62 plasmid, it was found that P62 plasmid can inhibit the lipid peroxidation of iron death in dopaminergic nerve cells by activating the Nrf2 signaling pathway, thus playing a protective role in dopaminergic nerve cells.PMID:38178661 | DOI:10.2174/0115665240266555231120044938 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Yani Yao Peishan Li Sen Jiang Xinling Meng Hua Gao Xinling Yang Source Type: research
TPD52 is a Potential Prognostic Biomarker and Correlated with Immune Infiltration: A Pan-cancer Analysis
CONCLUSION: The TPD52 gene may be important for human cancer treatment.PMID:38178662 | DOI:10.2174/0115665240260252230919054858 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Lu Miao Li Jing Buze Chen Tian Zeng Youguo Chen Source Type: research
ADGRL4 Promotes Cell Growth, Aggressiveness, EMT, and Angiogenesis in Neuroblastoma via Activation of ERK/STAT3 Pathway
CONCLUSION: To conclude, the downregulation of ADGRL4 may inhibit cell growth, aggressiveness, EMT, and angiogenesis in NB by inactivating the ERK/STAT3 signaling pathway.PMID:38178660 | DOI:10.2174/0115665240254765231117122210 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Geng Geng Lei Zhang Ying Yu Xingqing Guo Qinghao Li Ming Ming Source Type: research
A Mechanism Study on the Antioxidant Pathway of Keap1-Nrf2-ARE Inhibiting Ferroptosis in Dopaminergic Neurons
CONCLUSION: Based on the transfection of P62 plasmid, it was found that P62 plasmid can inhibit the lipid peroxidation of iron death in dopaminergic nerve cells by activating the Nrf2 signaling pathway, thus playing a protective role in dopaminergic nerve cells.PMID:38178661 | DOI:10.2174/0115665240266555231120044938 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Yani Yao Peishan Li Sen Jiang Xinling Meng Hua Gao Xinling Yang Source Type: research
TPD52 is a Potential Prognostic Biomarker and Correlated with Immune Infiltration: A Pan-cancer Analysis
CONCLUSION: The TPD52 gene may be important for human cancer treatment.PMID:38178662 | DOI:10.2174/0115665240260252230919054858 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Lu Miao Li Jing Buze Chen Tian Zeng Youguo Chen Source Type: research
ADGRL4 Promotes Cell Growth, Aggressiveness, EMT, and Angiogenesis in Neuroblastoma via Activation of ERK/STAT3 Pathway
CONCLUSION: To conclude, the downregulation of ADGRL4 may inhibit cell growth, aggressiveness, EMT, and angiogenesis in NB by inactivating the ERK/STAT3 signaling pathway.PMID:38178660 | DOI:10.2174/0115665240254765231117122210 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Geng Geng Lei Zhang Ying Yu Xingqing Guo Qinghao Li Ming Ming Source Type: research
A Mechanism Study on the Antioxidant Pathway of Keap1-Nrf2-ARE Inhibiting Ferroptosis in Dopaminergic Neurons
CONCLUSION: Based on the transfection of P62 plasmid, it was found that P62 plasmid can inhibit the lipid peroxidation of iron death in dopaminergic nerve cells by activating the Nrf2 signaling pathway, thus playing a protective role in dopaminergic nerve cells.PMID:38178661 | DOI:10.2174/0115665240266555231120044938 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Yani Yao Peishan Li Sen Jiang Xinling Meng Hua Gao Xinling Yang Source Type: research
TPD52 is a Potential Prognostic Biomarker and Correlated with Immune Infiltration: A Pan-cancer Analysis
CONCLUSION: The TPD52 gene may be important for human cancer treatment.PMID:38178662 | DOI:10.2174/0115665240260252230919054858 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - January 5, 2024 Category: Molecular Biology Authors: Lu Miao Li Jing Buze Chen Tian Zeng Youguo Chen Source Type: research
