Anlotinib Inhibiting Mantle Cell Lymphoma Proliferation and Inducing Apoptosis through PI3K/AKT/mTOR Pathway
CONCLUSION: Anlotinib effectively inhibits proliferation and induces apoptosis in MCL both in vitro and in vivo. This inhibition is likely linked to suppressing phosphorylation in the PI3K/Akt/mTOR pathway.PMID:38659267 | DOI:10.2174/0115665240284638240408081133 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - April 25, 2024 Category: Molecular Biology Authors: Jiaping Wang Zhijuan Xu Yanli Lai Yanli Zhang Ping Zhang Qitian Mu Shujun Yang Lixia Sheng Guifang Ouyang Source Type: research
Understanding the Roles of Non-coding RNAs and Exosomal Non-Coding RNAs in Diabetic Nephropathy
Curr Mol Med. 2024 Apr 5. doi: 10.2174/0115665240287631240321072504. Online ahead of print.ABSTRACTOne of the greatest serious side effects of diabetes is diabetic nephropathy (DN), which is also the key factor in the sometimes-deadly diabetic end-stage renal disease. Progressive renal interstitial fibrosis is closely associated with oxidative stress, and the extracellular matrix is typically a feature of DN. Some RNAs formed by genome transcription that are not translated into proteins are recognized as noncoding RNAs. It has been shown that ncRNAs control apoptosis, inflammatory response, cell proliferation, autophagy, a...
Source: Current Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Yuye Zhu Chunying Liu Jamal Hallajzadeh Source Type: research
Understanding the Roles of Non-coding RNAs and Exosomal Non-Coding RNAs in Diabetic Nephropathy
Curr Mol Med. 2024 Apr 5. doi: 10.2174/0115665240287631240321072504. Online ahead of print.ABSTRACTOne of the greatest serious side effects of diabetes is diabetic nephropathy (DN), which is also the key factor in the sometimes-deadly diabetic end-stage renal disease. Progressive renal interstitial fibrosis is closely associated with oxidative stress, and the extracellular matrix is typically a feature of DN. Some RNAs formed by genome transcription that are not translated into proteins are recognized as noncoding RNAs. It has been shown that ncRNAs control apoptosis, inflammatory response, cell proliferation, autophagy, a...
Source: Current Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Yuye Zhu Chunying Liu Jamal Hallajzadeh Source Type: research
Understanding the Roles of Non-coding RNAs and Exosomal Non-Coding RNAs in Diabetic Nephropathy
Curr Mol Med. 2024 Apr 5. doi: 10.2174/0115665240287631240321072504. Online ahead of print.ABSTRACTOne of the greatest serious side effects of diabetes is diabetic nephropathy (DN), which is also the key factor in the sometimes-deadly diabetic end-stage renal disease. Progressive renal interstitial fibrosis is closely associated with oxidative stress, and the extracellular matrix is typically a feature of DN. Some RNAs formed by genome transcription that are not translated into proteins are recognized as noncoding RNAs. It has been shown that ncRNAs control apoptosis, inflammatory response, cell proliferation, autophagy, a...
Source: Current Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Yuye Zhu Chunying Liu Jamal Hallajzadeh Source Type: research
Understanding the Roles of Non-coding RNAs and Exosomal Non-Coding RNAs in Diabetic Nephropathy
Curr Mol Med. 2024 Apr 5. doi: 10.2174/0115665240287631240321072504. Online ahead of print.ABSTRACTOne of the greatest serious side effects of diabetes is diabetic nephropathy (DN), which is also the key factor in the sometimes-deadly diabetic end-stage renal disease. Progressive renal interstitial fibrosis is closely associated with oxidative stress, and the extracellular matrix is typically a feature of DN. Some RNAs formed by genome transcription that are not translated into proteins are recognized as noncoding RNAs. It has been shown that ncRNAs control apoptosis, inflammatory response, cell proliferation, autophagy, a...
Source: Current Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Yuye Zhu Chunying Liu Jamal Hallajzadeh Source Type: research
Understanding the Roles of Non-coding RNAs and Exosomal Non-Coding RNAs in Diabetic Nephropathy
Curr Mol Med. 2024 Apr 5. doi: 10.2174/0115665240287631240321072504. Online ahead of print.ABSTRACTOne of the greatest serious side effects of diabetes is diabetic nephropathy (DN), which is also the key factor in the sometimes-deadly diabetic end-stage renal disease. Progressive renal interstitial fibrosis is closely associated with oxidative stress, and the extracellular matrix is typically a feature of DN. Some RNAs formed by genome transcription that are not translated into proteins are recognized as noncoding RNAs. It has been shown that ncRNAs control apoptosis, inflammatory response, cell proliferation, autophagy, a...
Source: Current Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Yuye Zhu Chunying Liu Jamal Hallajzadeh Source Type: research
Understanding the Roles of Non-coding RNAs and Exosomal Non-Coding RNAs in Diabetic Nephropathy
Curr Mol Med. 2024 Apr 5. doi: 10.2174/0115665240287631240321072504. Online ahead of print.ABSTRACTOne of the greatest serious side effects of diabetes is diabetic nephropathy (DN), which is also the key factor in the sometimes-deadly diabetic end-stage renal disease. Progressive renal interstitial fibrosis is closely associated with oxidative stress, and the extracellular matrix is typically a feature of DN. Some RNAs formed by genome transcription that are not translated into proteins are recognized as noncoding RNAs. It has been shown that ncRNAs control apoptosis, inflammatory response, cell proliferation, autophagy, a...
Source: Current Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Yuye Zhu Chunying Liu Jamal Hallajzadeh Source Type: research
Understanding the Roles of Non-coding RNAs and Exosomal Non-Coding RNAs in Diabetic Nephropathy
Curr Mol Med. 2024 Apr 5. doi: 10.2174/0115665240287631240321072504. Online ahead of print.ABSTRACTOne of the greatest serious side effects of diabetes is diabetic nephropathy (DN), which is also the key factor in the sometimes-deadly diabetic end-stage renal disease. Progressive renal interstitial fibrosis is closely associated with oxidative stress, and the extracellular matrix is typically a feature of DN. Some RNAs formed by genome transcription that are not translated into proteins are recognized as noncoding RNAs. It has been shown that ncRNAs control apoptosis, inflammatory response, cell proliferation, autophagy, a...
Source: Current Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Yuye Zhu Chunying Liu Jamal Hallajzadeh Source Type: research
Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy
CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research
Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy
CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research
Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy
CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research
Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy
CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research
Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy
CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research
Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy
CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research
Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy
CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research
