MiR-148b caused liver injury in rats with traumatic hemorrhagic shock by inhibiting SIRT6 expression
CONCLUSION: Hepatocyte injury induced by I/R was achieved by regulating miR-148b /SIRT6 axis.PMID:37587827 | DOI:10.2174/1566524023666230816112629 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - August 17, 2023 Category: Molecular Biology Authors: Xiongfei Ma Mingchen Liu Source Type: research

Sema3A alleviates the malignant behaviors of gastric cancer cells by inhibiting NRP-1
CONCLUSION: In conclusion, Sema3a alleviates the proliferation, migration, invasion, and angiogenesis capabilities of gastric cancer cells via repressing NRP-1. This finding may provide potential targets for gastric cancer therapy.PMID:37533240 | DOI:10.2174/1566524023666230801124826 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - August 3, 2023 Category: Molecular Biology Authors: Hongqiong Yang Yaojun Zhou Liangzhi Wang Mengjia Lv Jinling Sun Zhenguo Luo Junbo He Source Type: research

Aminoglycosides: single- or multiple-daily dosing? An updated qualitative systematic review of randomized trials on toxicity and efficacy
CONCLUSION: In most studies, there were no significant differences between the two regimens regarding ototoxicity. In addition, the ODD regimens were safer than MDD concerning nephrotoxicity.PMID:37533241 | DOI:10.2174/1566524023666230801160452 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - August 3, 2023 Category: Molecular Biology Authors: Iman Karimzadeh Meghdad Abdollahpour-Alitappeh Shokouh Ghaffari Motahareh Mahi-Birjand Amin Barkhordari Effat Alemzadeh Source Type: research

Sema3A alleviates the malignant behaviors of gastric cancer cells by inhibiting NRP-1
CONCLUSION: In conclusion, Sema3a alleviates the proliferation, migration, invasion, and angiogenesis capabilities of gastric cancer cells via repressing NRP-1. This finding may provide potential targets for gastric cancer therapy.PMID:37533240 | DOI:10.2174/1566524023666230801124826 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - August 3, 2023 Category: Molecular Biology Authors: Hongqiong Yang Yaojun Zhou Liangzhi Wang Mengjia Lv Jinling Sun Zhenguo Luo Junbo He Source Type: research

Aminoglycosides: single- or multiple-daily dosing? An updated qualitative systematic review of randomized trials on toxicity and efficacy
CONCLUSION: In most studies, there were no significant differences between the two regimens regarding ototoxicity. In addition, the ODD regimens were safer than MDD concerning nephrotoxicity.PMID:37533241 | DOI:10.2174/1566524023666230801160452 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - August 3, 2023 Category: Molecular Biology Authors: Iman Karimzadeh Meghdad Abdollahpour-Alitappeh Shokouh Ghaffari Motahareh Mahi-Birjand Amin Barkhordari Effat Alemzadeh Source Type: research