CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
CCN3/NOV Serum Levels in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients in Comparison with the Healthy Group and their Correlation with TNF- α and IL-6
CONCLUSION: It was found that elevated CCN3 serum levels directly correlate with NAFLD incidence and inflammation markers (IL-6 and TNF-α). CCN3 could serve as a potential biomarker for NAFLD, but further research is needed to validate this finding and assess its clinical utility.PMID:38415473 | DOI:10.2174/0115665240285539240214111947 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 28, 2024 Category: Molecular Biology Authors: Reza Afrisham Ghazal Alasvand Yasaman Jadidi Vida Farrokhi Reza Fadaei Shaban Alizadeh Nariman Moradi Source Type: research
Metabolic Derangement in Non-Alcoholic Fatty Liver Disease: Opportunities for Early Diagnostic and Prognostic Markers
Curr Mol Med. 2024 Feb 22. doi: 10.2174/0115665240269082240213115711. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease is a globally prevalent disorder that can rapidly progress if not detected early. Currently, no accepted markers exist for early diagnosis and prognosis of NAFLD. This review describes derangement in major metabolic pathways of lipid, carbohydrate, and amino acids in NAFLD. It suggests that measuring levels of thrombospondin, TyG index, asymmetric dimethylarginine, LAL-A, GLP-1, FGF-21, and GSG index are potential markers for early diagnosis of NAFLD. A single marker may not indicate early N...
Source: Current Molecular Medicine - February 27, 2024 Category: Molecular Biology Authors: Verma Abhinav Rishabh Mittal Mathiyazhagan Navaneethakannan Ahirwar Sonu Singh Mukherjee Sukhes Kotnis Ashwin Source Type: research
Metabolic Derangement in Non-Alcoholic Fatty Liver Disease: Opportunities for Early Diagnostic and Prognostic Markers
Curr Mol Med. 2024 Feb 22. doi: 10.2174/0115665240269082240213115711. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease is a globally prevalent disorder that can rapidly progress if not detected early. Currently, no accepted markers exist for early diagnosis and prognosis of NAFLD. This review describes derangement in major metabolic pathways of lipid, carbohydrate, and amino acids in NAFLD. It suggests that measuring levels of thrombospondin, TyG index, asymmetric dimethylarginine, LAL-A, GLP-1, FGF-21, and GSG index are potential markers for early diagnosis of NAFLD. A single marker may not indicate early N...
Source: Current Molecular Medicine - February 27, 2024 Category: Molecular Biology Authors: Verma Abhinav Rishabh Mittal Mathiyazhagan Navaneethakannan Ahirwar Sonu Singh Mukherjee Sukhes Kotnis Ashwin Source Type: research
Anti-Cancer and Anti-Oxidant Effects of Fenoferin-loaded Human Serum Albumin Nanoparticles Coated with Folic Acid-bound Chitosan
CONCLUSION: According to this study, synthesized nanoparticles inhibited free radicals and activated apoptosis in liver cancer cells, and the capability of these nanoparticles to inhibit cancer cells was also confirmed. This formulation can, therefore, be used in preclinical studies to test the efficacy of the drug.PMID:38375838 | DOI:10.2174/0115665240283529240202095254 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 20, 2024 Category: Molecular Biology Authors: Methaq Abid Said Klmohamed Almusawi Vahid Pouresmaeil Masoud Homayouni Tabrizi Source Type: research
A Systematic Review of the Impact of Resveratrol on Viral Hepatitis and Chronic Viral Hepatitis-related Hepatocellular Carcinoma
CONCLUSION: Despite the promising properties of RSV in inhibiting hepatitis-related HCC cell proliferation, its antiviral effects in viral hepatitis are controversial. The antihepatitis behaviors of RSV are mainly dose-dependent, and in some studies, activating some hepatoprotective pathways increases the transcription and replication of chronic HBV and HCV. Therefore, healthcare providers should be aware of viral hepatitis before using RSV supplements.PMID:38375839 | DOI:10.2174/0115665240284347240125072555 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 20, 2024 Category: Molecular Biology Authors: Mohammad Darvishi Majid Nouri Rasoul Rahimi Saeid Heidari-Soureshjani Seyed Mahmood Reza Hashemi Rafsanjani Source Type: research
Anti-Cancer and Anti-Oxidant Effects of Fenoferin-loaded Human Serum Albumin Nanoparticles Coated with Folic Acid-bound Chitosan
CONCLUSION: According to this study, synthesized nanoparticles inhibited free radicals and activated apoptosis in liver cancer cells, and the capability of these nanoparticles to inhibit cancer cells was also confirmed. This formulation can, therefore, be used in preclinical studies to test the efficacy of the drug.PMID:38375838 | DOI:10.2174/0115665240283529240202095254 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 20, 2024 Category: Molecular Biology Authors: Methaq Abid Said Klmohamed Almusawi Vahid Pouresmaeil Masoud Homayouni Tabrizi Source Type: research
A Systematic Review of the Impact of Resveratrol on Viral Hepatitis and Chronic Viral Hepatitis-related Hepatocellular Carcinoma
CONCLUSION: Despite the promising properties of RSV in inhibiting hepatitis-related HCC cell proliferation, its antiviral effects in viral hepatitis are controversial. The antihepatitis behaviors of RSV are mainly dose-dependent, and in some studies, activating some hepatoprotective pathways increases the transcription and replication of chronic HBV and HCV. Therefore, healthcare providers should be aware of viral hepatitis before using RSV supplements.PMID:38375839 | DOI:10.2174/0115665240284347240125072555 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 20, 2024 Category: Molecular Biology Authors: Mohammad Darvishi Majid Nouri Rasoul Rahimi Saeid Heidari-Soureshjani Seyed Mahmood Reza Hashemi Rafsanjani Source Type: research
Anti-Cancer and Anti-Oxidant Effects of Fenoferin-loaded Human Serum Albumin Nanoparticles Coated with Folic Acid-bound Chitosan
CONCLUSION: According to this study, synthesized nanoparticles inhibited free radicals and activated apoptosis in liver cancer cells, and the capability of these nanoparticles to inhibit cancer cells was also confirmed. This formulation can, therefore, be used in preclinical studies to test the efficacy of the drug.PMID:38375838 | DOI:10.2174/0115665240283529240202095254 (Source: Current Molecular Medicine)
Source: Current Molecular Medicine - February 20, 2024 Category: Molecular Biology Authors: Methaq Abid Said Klmohamed Almusawi Vahid Pouresmaeil Masoud Homayouni Tabrizi Source Type: research
