Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy

CONCLUSION: Nef improved HN by inhibiting macrophages polarized to M1-type and pyroptosis by targeting the NLRC5/NLRP3 pathway. This research provides a scientific theoretical basis for the treatment of HN.PMID:38549521 | DOI:10.2174/0115665240272051240122074511

Source: Current Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Wei Yin Jin-Hua Wang Yu-Mei Liang Kang-Han Liu Ying Chen Yusa Chen Source Type: research