Cellular Physiology and Biochemistry 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Microarray Profiling of TGF- β1-Induced Long Non-Coding RNA Expression Patterns in Human Lung Bronchial Epithelial BEAS-2B Cells
Conclusion: Our findings suggest that the differentially expressed lncRNAs induced by TGF- β1 play crucial roles in the oncogenic transformation and tumorigenesis, which provide a better understanding of the underlying mechanisms related to tumorigensis induced by LD/LDR radiations.Cell Physiol Biochem 2018;50:2071 –2085 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Global mRNA and Long Non-Coding RNA Expression in the Placenta and White Adipose Tissue of Mice Fed a High-Fat Diet During Pregnancy
Conclusion: These newly identified key genes and pathways in mice might provide valuable information regarding the pathogenesis of GDM and might be used to improve early diagnosis, prevention, drug design, and clinical treatment.Cell Physiol Biochem 2018;50:2260 –2271 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Mice Deficient in Cyp4a14 Have An Increased Number of Goblet Cells and Attenuated Dextran Sulfate Sodium-Induced Colitis
Conclusion: These results suggests a hypothesis that the increased goblet cell in the colon of Cyp4a14-KO mice provides protection from mucosal injury and Cyp4a14-increased oxidative stress exacerbates DSS-induced colitis. Therefore, Cyp4a14 may represent a potential target for treating colitis.Cell Physiol Biochem 2018;50:2272 –2282 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Stimulation of Eryptosis, the Suicidal Erythrocyte Death, by Costunolide
Conclusion: Costunolide triggers cell shrinkage and phospholipid scrambling of the erythrocyte cell membrane, an effect at least in part due to Ca2+ entry and paralleled by oxidative stress and ceramide formation.Cell Physiol Biochem 2018;50:2283 –2295 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Ca < sup > 2+ < /sup > Signaling Triggered by Shear-Autocrine P2X Receptor Pathway in Rat Atrial Myocytes
Conclusion: Our data suggest that shear stress triggers APs and concomitant Ca2+ signaling via activation of P2X receptors by connexin hemichannel-mediated ATP release in atrial myocytes.Cell Physiol Biochem 2018;50:2296 –2313 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Constitutively Photomorphogenic 1 Reduces the Sensitivity of Chronic Lymphocytic Leukemia Cells to Fludarabine Through Promotion of Ubiquitin-Mediated P53 Degradation
Conclusion: This study demonstrates that COP1 contributes to drug resistance of CLL cells to the fludarabine treatmentin vitro andin vivo.Cell Physiol Biochem 2018;50:2314 –2328 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Effects of Triple-Mutated Hypoxia-Inducible Factor-1 α on Angiogenesis and Cardiac Function Improvement in Rats with Myocardial Infarction
Conclusion: Mutation of Pro402, Pro564 and Asn803 are beneficial for enhancement of the efficacy of HIF-1 α. Ad-HIF–1α-Trip is able to improve angiogenesis and cardiac function, which may be a promising avenue for treatment of ischemic heart disease in the future.Cell Physiol Biochem 2018;50:2329 –2340 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Peperomin E Induces Promoter Hypomethylation of Metastatic-Suppressor Genes and Attenuates Metastasis in Poorly Differentiated Gastric Cancer
Conclusion: Collectively, our data indicated that PepE may represent a promising therapeutic lead compound for intervention in gastric cancer metastasis and may also exhibit potential as a DNA methylation inhibitor for use in epigenetic cancer therapy.Cell Physiol Biochem 2018;50:2341 –2364 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
MicroRNA-200a Affects the Proliferation of Airway Smooth Muscle Cells and Airway Remodeling by Targeting FOXC1 via the PI3K/AKT Signaling Pathway in Ovalbumin-Induced Asthmatic Mice
Conclusion: The overexpression of miR-200a may downregulate FOXC1, thereby inhibiting the activation of the PI3K/AKT signaling pathway and ultimately suppressing ASMC proliferation and airway remodeling in asthmatic mice. This evidence supports the potential that miR-200a represents a new approach to treating asthma.Cell Physiol Biochem 2018;50:2365 –2389 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Novel Zinc Finger Transcription Factor ZFP580 Facilitates All-Trans Retinoic Acid -Induced Vascular Smooth Muscle Cells Differentiation by Rar α-Mediated PI3K/Akt and ERK Signaling
Conclusion: The novel zinc finger transcription factor ZFP580 facilitates ATRA-induced VSMC differentiation by the RAR α-mediated PI3K/Akt and ERK signaling pathways. This might represent a novel mechanism of regulation of ZFP580 by ATRA and RARα, which is critical for understanding the biological functions of retinoids during VSMC phenotypic modulation.Cell Physiol Biochem 2018;50:2390 –2405 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
Genome-Wide Analysis of mRNAs and lncRNAs of Intramuscular Fat Related to Lipid Metabolism in Two Pig Breeds
Conclusion:XLOC_046142, XLOC_004398 andXLOC_015408 may targetMAPKAPK2, NR1D2 andAKR1C4, respectively, and play critical regulatory roles in intramuscular adipogenesis and lipid accumulation in pig.XLOC_064871 andXLOC_011001 may play a role in lipid metabolism-related disease via regulatingTRIB3 andBRCA1. This study provides a valuable resource for lncRNA study and improves our understanding of the biological roles of lipid metabolism- related genes and molecular mechanism of intramuscular fat metabolism and deposition.Cell Physiol Biochem 2018;50:2406 –2422 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 13, 2018 Category: Cytology Source Type: research
MALAT1 Activates the P53 Signaling Pathway by Regulating MDM2 to Promote Ischemic Stroke
Conclusion: These results indicate that MALAT1/MDM2/p53 signaling pathway axis may provide more effective clinical therapeutic strategy for patients with ischemic stroke.Cell Physiol Biochem 2018;50:2216 –2228 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 12, 2018 Category: Cytology Source Type: research
miR-142-5p Improves Neural Differentiation and Proliferation of Adipose-Derived Stem Cells
Conclusion: Our results demonstrate that miR-142-5p functions as a growth promotive miRNA and plays an important role in neurogenic differentiation by targeting RhoA/ROCK1 in ADSCs.Cell Physiol Biochem 2018;50:2097 –2107 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 9, 2018 Category: Cytology Source Type: research
PFKFB4 Promotes Breast Cancer Metastasis via Induction of Hyaluronan Production in a p38-Dependent Manner
Conclusion: PFKFB4 promotes the metastasis of breast cancer cells via induction of HAS2 expression and HA production in a p38-dependent manner. Therefore, the PFKFB4/p38/HAS2 signaling pathway may serve as a potential therapeutic target for metastatic breast cancer.Cell Physiol Biochem 2018;50:2108 –2123 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 9, 2018 Category: Cytology Source Type: research
HOXA-AS2 Promotes Proliferation and Induces Epithelial-Mesenchymal Transition via the miR-520c-3p/GPC3 Axis in Hepatocellular Carcinoma
Conclusion: In summary, our results suggested that the HOXA-AS2/miR-520c-3p/GPC3 axis may play an important role in the regulation of PTC progression, which could serve as a biomarker and therapeutic target for HCC.Cell Physiol Biochem 2018;50:2124 –2138 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 9, 2018 Category: Cytology Source Type: research
