Cellular Physiology and Biochemistry 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.circZMYM2 Competed Endogenously with miR-335-5p to Regulate JMJD2C in Pancreatic Cancer
Conclusion: Our study demonstrated that circZMYM2 promoted PC progression. CircZMYM2 had a sponge effect on miR-335-5p and modulated the downstream oncogeneJMJD2C.Cell Physiol Biochem 2018;51:2224 –2236 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1 α and Collagen Type XV Correlation
Conclusion: These results add useful information to understand the role of a still little investigated collagen such as ColXV, and identify ColXV as a marker of successful hypoxia preconditioning. As a whole, our data give further evidence that hypoxia preconditioned hMSCs have greater osteopotency than normal hMSCs, and that the effects of hypoxic regulation of hMSCs activities should be considered before they are clinically applied.Cell Physiol Biochem 2018;51:2237 –2249 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
Tanshinone IIA Inhibits High Glucose-Induced Collagen Synthesis via Nuclear Factor Erythroid 2-Related Factor 2 in Cardiac Fibroblasts
Conclusion: In summary, our results highlights the critical role tanshinone IIA plays as an antioxidant in attenuating high glucose-mediated collagen synthesis through inhibiting TGF- β1/Smad signaling in cardiac fibroblasts which provide a mechanistic basis for the clinical application of tanshinone IIA in the treating diabetic-related cardiac fibrosis.Cell Physiol Biochem 2018;51:2250 –2261 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
lncRNA SNHG8 Promotes the Tumorigenesis and Metastasis by Sponging miR-149-5p and Predicts Tumor Recurrence in Hepatocellular Carcinoma
Conclusion: As lncRNA SNHG8 may promote HCC tumorigenesis and metastasis by sponging miR-149, it is a potential candidate marker and therapeutic target for HCC.Cell Physiol Biochem 2018;51:2262 –2274 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
MicroRNA-128 Protects Dopamine Neurons from Apoptosis and Upregulates the Expression of Excitatory Amino Acid Transporter 4 in Parkinson ’s Disease by Binding to AXIN1
Conclusion: Evidence from experimental models revealed that miR-128 might reduce apoptosis of DA neurons while increasing the expression of EAAT4 which might be related to the downregulation of AXIN1. Thus, miR-128 may serve as a potential target for the treatment of PD.Cell Physiol Biochem 2018;51:2275 –2289 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
Dental Follicle Stem Cells Ameliorate Lipopolysaccharide-Induced Inflammation by Secreting TGF- β3 and TSP-1 to Elicit Macrophage M2 Polarization
Conclusion: These results indicated that DFSCs can reprogram macrophages into the anti-inflammatory M2 phenotype, the paracrine factors TGF- β3 and TSP-1 may be one of the underlying mechanisms. This study supports the hypothesis that DFSCs are promising for MSC-based immunotherapy.Cell Physiol Biochem 2018;51:2290 –2308 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
The Transient Receptor Potential Channel, Vanilloid 5, Induces Chondrocyte Apoptosis via Ca < sup > 2+ < /sup > CaMKII –Dependent MAPK and Akt/ mTOR Pathways in a Rat Osteoarthritis Model
Conclusion: Our results demonstrate that upregulated TRPV5 may be an important initiating factor that activates CaMKII phosphorylation via the mediation of Ca2+ influx. In turn, activated p-CaMKII plays a critical role in chondrocyte apoptosis via MAPK and Akt/mTOR pathways.Cell Physiol Biochem 2018;51:2309 –2323 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
Circular RNA circPVT1 Promotes Proliferation and Invasion Through Sponging miR-125b and Activating E2F2 Signaling in Non-Small Cell Lung Cancer
Conclusion: circPVT1 promotes NSCLC cell growth and invasion, and may serve as a promising therapeutic target for NSCLC patients. Therefore, silence of circPVT1 could be a future direction to develop a novel treatment strategy.Cell Physiol Biochem 2018;51:2324 –2340 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation
Conclusion: Consecutive superovulation significantly decreased ovarian function and oocyte quality and increased oxidative stress and apoptosis in the ovary via a mechanism involving the p16 and SIRT1/FOXO1 signaling pathways. These findings suggest that consecutive superovulation may be used to establish a mouse model of ovarian aging.Cell Physiol Biochem 2018;51:2341 –2358 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
Mammalian STE20-Like Kinase 1 Deletion Alleviates Renal Ischaemia-Reperfusion Injury via Modulating Mitophagy and the AMPK-YAP Signalling Pathway
Conclusion: Overall, our results demonstrate that the pathogenesis of renal I/R injury is closely associated with an increase in Mst1 expression and the inactive AMPK-YAP-OPA1 signalling pathway. Based on this, strategies to repress Mst1 expression and activate mitophagy could serve as therapeutic targets to treat kidney ischaemia-reperfusion injury.Cell Physiol Biochem 2018;51:2359 –2376 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 7, 2018 Category: Cytology Source Type: research
Clinicopathologic Features and Prognostic Factors in Alpha-Fetoprotein-Producing Colorectal Cancer: Analysis of 78 Cases
Conclusion: AFP-positivity is a significant negative predictor of overall survival in patients with colorectal cancer, which may be mediated by HGF/c-Met signaling pathway.Cell Physiol Biochem 2018;51:2052 –2064 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 6, 2018 Category: Cytology Source Type: research
Potential Role of microRNA-183 as a Tumor Suppressor in Hepatocellular Carcinoma
Conclusion: Our results reveal a novel post-transcriptional regulatory mechanism forMTA1 expression via miR-183, which is suppressed during HCC pathogenesis.Cell Physiol Biochem 2018;51:2065 –2072 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 6, 2018 Category: Cytology Source Type: research
Clinical Drug Response Prediction by Using a Lq Penalized Network-Constrained Logistic Regression Method
Conclusion: The proposed method is much better than the existing approach and can capture a more accurate reflection of the relationship between genotypes and phenotypes.Cell Physiol Biochem 2018;51:2073 –2084 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 6, 2018 Category: Cytology Source Type: research
Gliquidone Alleviates Diabetic Nephropathy by Inhibiting Notch/Snail Signaling Pathway
Conclusion: Taken together, our results suggested that gliquidone can ameliorate the diabetic symptoms of diabetic nephropathy through inhibiting Notch / Snail1 signaling pathway, improving anti -oxidative response and delaying renal interstitial fibrosis. The efficacy of gliquidone is dose-dependent.Cell Physiol Biochem 2018;51:2085 –2097 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 6, 2018 Category: Cytology Source Type: research
Blocking TRPA1 and TNF- α Signal Improves Bortezomib-Induced Neuropathic Pain
Conclusion: We revealed specific signaling pathways leading to neuropathic pain induced by chemotherapeutic BTZ. The data also suggest that blocking TRPA1 and tumor necrosis factor alpha is beneficial to alleviate neuropathic pain during BTZ intervention.Cell Physiol Biochem 2018;51:2098 –2110 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - December 6, 2018 Category: Cytology Source Type: research
