Cellular Physiology and Biochemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Inhibition of microRNA-200a Upregulates the Expression of Striatal Dopamine Receptor D2 to Repress Apoptosis of Striatum via the cAMP/PKA Signaling Pathway in Rats with Parkinson ’s Disease
Conclusion: This study provides evidence that the inhibition of miR-200a can repress apoptosis in the striatum via inhibition of the cAMP/PKA signaling pathway by upregulating DRD2 expression in PD rats.Cell Physiol Biochem 2018;51:1600 –1615 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 29, 2018 Category: Cytology Source Type: research

microRNA-29a-3p, Up-Regulated in Human Gastric Cells and Tissues with H.Pylori Infection, Promotes the Migration of GES-1 Cells via A20-Mediated EMT Pathway
Conclusion: The miR-29a-3p may act as a tumor promotive miRNA by regulating cells migration through directly targeting of A20 gene in human gastric epithelial cells infected withH.pylori.Cell Physiol Biochem 2018;51:1250 –1263 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

Comprehensive Circular RNA Profiling Reveals the Regulatory Role of the CircRNA-0067835/miR-155 Pathway in Temporal Lobe Epilepsy
Conclusion: Our experiments showed that circRNA-0067835 regulated refractory epilepsy progression by acting as a sponge of miR-155 to promote FOXO3a expression, indicating that circRNA-0067835 may serve as a potential therapeutic target for patients with TLE.Cell Physiol Biochem 2018;51:1399 –1409 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy
Conclusion: Taken together, these results provide new insight into the association between 150Rik and the miR-451/IGF1R/p38MAPK signaling pathway during DN progression.Cell Physiol Biochem 2018;51:1410 –1428 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

Beta Adrenergic Receptors Stimulation Attenuates Phosphorylation of NF- κB and IκBα in Hyperglycemic Endothelial Cells
Conclusion: Given data demonstrates that beta-adrenergic receptors stimulation has a protective effect on HUVECs that might be occuring via NF- κβ and IκBα pathway.Cell Physiol Biochem 2018;51:1429 –1436 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

Characterization of the Transcriptome of Hair Cell Regeneration in the Neonatal Mouse Utricle
Conclusion: Our results provide a valuable source for future studies and highlighted some promising genes, pathways or processes that may be useful for therapeutic applications.Cell Physiol Biochem 2018;51:1437 –1447 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

Alpha-Lipoic Acid Preconditioning and Ischaemic Postconditioning Synergistically Protect Rats from Cerebral Injury Induced by Ischemia and Reperfusion Partly via Inhibition TLR4/MyD88/ NF- κB Signaling Pathway
Conclusion: The ‘cocktail’ strategy exhibited a significant neuroprotection against I/RI by attenuating neuroinflammation via inhibition of the TLR4/MyD88/NF-κB signaling pathway.Cell Physiol Biochem 2018;51:1448 –1460 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

Different PDGF Receptor Dimers Drive Distinct Migration Modes of the Mouse Skin Fibroblast
Conclusion: This is the first systematic study that characterized the chemotaxis mediated by three-different types of PDGFR dimers in mesenchymal cell migration. Our data demonstrate that PDGFR dimer formation is the critical step to determine the specific mode of fibroblast chemotaxis, while the accompanying cytoskeletal remodeling might contribute to migration persistence.Cell Physiol Biochem 2018;51:1461 –1479 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

The Serum microRNA Profile of Intrahepatic Cholestasis of Pregnancy: Identification of Novel Noninvasive Biomarkers
Conclusion: This preliminary work improves our understanding of serum miRNA changes in pregnant women with ICP. The three miRNAs may serve as novel noninvasive biomarkers of ICP.Cell Physiol Biochem 2018;51:1480 –1488 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR
Conclusion: STX8 knockdown creates an environment favorable for mature ΔF508 to reach the cell surface. The data also suggest that when present at normal levels, STX8 functions as part of the cell’s quality control mechanism.Cell Physiol Biochem 2018;51:1489 –1499 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 28, 2018 Category: Cytology Source Type: research

Metformin Inhibited Growth, Invasion and Metastasis of Esophageal Squamous Cell Carcinoma in Vitro and in Vivo 
Conclusion: Our study for the first time demonstrated the anti-invasive and anti-metastatic effects of metformin on human ESCC cells bothin vitro andin vivo, which might be associated with the down-regulation of MMP-2 and MMP-9. As a whole, our results indicate the potential of metformin to be developed as a chemotherapeutic agent for patients with ESCC and might stimulate future studies on this area.Cell Physiol Biochem 2018;51:1276 –1286 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 27, 2018 Category: Cytology Source Type: research

Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease
Conclusion: Our results indicate that the potentiation of the antioxidant pathways can be an effective strategy to improve endothelial dysfunction in uremia and a potential target to reduce the cardiovascular risk in this population.Cell Physiol Biochem 2018;51:1287 –1300 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 27, 2018 Category: Cytology Source Type: research

A Heterozygous Missense hERG Mutation Associated with Early Repolarization Syndrome
Conclusion: Our study indicated that the K801T mutation caused the gain of function of hERG channels that may account for the clinical phenotype of ERS. Quinidine and disopyramide could improve the function of K801T-hERG mutant channel, and may be therapeutic options for patients with the K801T hERG mutation.Cell Physiol Biochem 2018;51:1301 –1312 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 27, 2018 Category: Cytology Source Type: research

LncRNA MALAT1 Promotes Cancer Metastasis in Osteosarcoma via Activation of the PI3K-Akt Signaling Pathway
Conclusion: Our data revealed for the first time that MALAT1 increases stem cell-like properties by up-regulating RET via sponging miR-129-5p, and thus activates the PI3K-Akt signaling pathway and provides potential therapeutic targets for osteosarcoma treatment.Cell Physiol Biochem 2018;51:1313 –1326 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 27, 2018 Category: Cytology Source Type: research

iTRAQ-Based Differential Proteomic Analysis Reveals the Pathways Associated with Tigecycline Resistance in Acinetobacter baumannii 
Conclusion: These results may provide new insights into the mechanisms of drug resistance inAcinetobacter baumannii.Cell Physiol Biochem 2018;51:1327 –1339 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 27, 2018 Category: Cytology Source Type: research