Cellular Physiology and Biochemistry 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Resveratrol Activated Sonic Hedgehog Signaling to Enhance Viability of NIH3T3 Cells < b > < i > in Vitro < /i > < /b > via Regulation of Sirt1
Conclusion: We indicate in the first time that it may be mediated by Sirt1 for resveratrol activating the Shh signaling to enhance viability of NIH3T3 cells, and Sirt1 may be a regulator for upstream of the Shh signaling pathway.This study provides a basis for further investigating effects and mechanism of resveratrol during the formation of fibrous scar after brain or spinal cord injury.Cell Physiol Biochem 2018;50:1346 –1360 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Slc4a8 in the Kidney: Expression, Subcellular Localization and Role in Salt Reabsorption
Conclusion: Slc4a8 (NDCBE) is absent in the CCD and is predominantly localized on the basolateral membrane of medullary collecting duct cells. Further, Slc4a8 deletion does not cause significant acid base or electrolyte abnormalities in pathophysiologic states. Additional studies are needed to examine the role of Slc4a8 (NDCBE) in intracellular pH and volume regulation in medullary collecting duct cells.Cell Physiol Biochem 2018;50:1361 –1375 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Dynamic Methylation Changes of DNA and H3K4 by RG108 Improve Epigenetic Reprogramming of Somatic Cell Nuclear Transfer Embryos in Pigs
Conclusion: Dynamic changes in DNA methylation caused by RG108 result in dynamic alterations in the patterns of H3K4me3, H3K9Ac and histone H3 lysine 9 trimethylation (H3K9me3), which leads to the activation of embryonic genome and epigenetic modification enzymes associated with H3K4 methylation, and contributes to reconstructing normal epigenetic modifications and improving the developmental efficiency of porcine SCNT embryos.Cell Physiol Biochem 2018;50:1376 –1397 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
The Effects of miR-195-5p/MMP14 on Proliferation and Invasion of Cervical Carcinoma Cells Through TNF Signaling Pathway Based on Bioinformatics Analysis of Microarray Profiling
Conclusion: Our results suggest that MMP14 is a direct target of miR-195-5p, and down-regulated MMP14 and up-regulated miR-195-5p suppressed proliferation and invasion of CC cells by inhibiting TNF signaling pathway.Cell Physiol Biochem 2018;50:1398 –1413 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Blood-Stage Plasmodium Berghei ANKA Infection Promotes Hepatic Fibrosis by Enhancing Hedgehog Signaling in Mice
Conclusion: Our results demonstrate that HSCs are activated in and Hh and YAP signaling are associated with this process, contributing to increased hepatic fibrosis in malaria-infected livers.Cell Physiol Biochem 2018;50:1414 –1428 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Circulating Long Noncoding RNAs as Biomarkers for Predicting Head and Neck Squamous Cell Carcinoma
Conclusion: HOXA11-AS, LINC00964 and MALAT1 might be potential circulating biomarkers for the early detection of HNSCC in the future.Cell Physiol Biochem 2018;50:1429 –1440 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
The Differentially Expressed Circular RNAs in the Substantia Nigra and Corpus Striatum of Nrf2-Knockout Mice
Conclusion: In conclusion, our study identified the key DEcircRNAs in the substantia nigra and corpus striatum of Nrf2 (-/-) mice, which might provide new clues for further exploring the mechanism of Nrf2-mediated neuroprotection against oxidative stress and other Nrf2-mediated processes.Cell Physiol Biochem 2018;50:936 –951 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
UCP2 Mitigates the Loss of Human Spermatozoa Motility by Promoting mROS Elimination
Conclusion: These results suggest an UCP2 –mROS–motility regulatory system exists for maintaining spermatozoa mobility in humans. In such a system, UCP2 fulfills its function by promoting mROS elimination, and slightly over-produced mROS in turn serves as a signal to stimulates the expression of UCP2. This regulatory system represents a new potential target for the discovery of novel pharmaceuticals for the treatment of patients with low spermatozoa motility.Cell Physiol Biochem 2018;50:952 –962 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
LY2109761, Transforming Growth Factor β Receptor Type I and Type II Dual Inhibitor, is a Novel Approach to Suppress Endothelial Mesenchymal Transformation in Human Corneal Endothelial Cells
Conclusion: Inhibition of TGF- β receptor type I and type II by LY2109761 maintained the phenotype of CECs and inhibited the EnMT process. These results indicate the possible continuousin vitro expansion of CECs with normal function.Cell Physiol Biochem 2018;50:963 –972 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
High Glucose-Mediated Cytokine Regulation in Gingival Fibroblasts and THP-1 Macrophage: a Possible Mechanism of Severe Periodontitis with Diabetes
Conclusion: Diabetic conditions such as HG induce IL-1 β and sIL-6R production from macrophages in inflammatory periodontal tissues and may exacerbate the periodontitis synergistically via MMP-1 production from HGFs.Cell Physiol Biochem 2018;50:973 –986 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Downregulation of N-Acetylglucosaminyltransferase GCNT3 by miR-302b-3p Decreases Non-Small Cell Lung Cancer (NSCLC) Cell Proliferation, Migration and Invasion
Conclusion: miR-302b-3p/GCNT3 axis regulated cell proliferation, migration, and invasion by activating the Erk signaling pathway and epithelial-mesenchymal transition (EMT), which was identified as a potential therapeutic target for NSCLC.Cell Physiol Biochem 2018;50:987 –1004 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Downregulation of miR-31 in Diabetic Nephropathy and its Relationship with Inflammation
Conclusion: Serum miR-31 may be a biomarker for DN in T2D patients. The regulation of this miRNA seems to be related to the recruitment of leukocytes to vascular walls induced by pro-inflammatory and adhesion molecules.Cell Physiol Biochem 2018;50:1005 –1014 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Periodic Mechanical Stress Stimulates GIT1-Dependent Mitogenic Signals in Rat Chondrocytes Through ERK1/2 Activity
Conclusion: These findings collectively suggested that periodic mechanical stress promoted chondrocyte proliferation through at least two separate pathways, integrin β1-Src-GIT1-FAK(Tyr576/577)-ERK1/2, and the other parallel GIT1-independent integrin β1-FAK(Tyr397)-ERK1/2.Cell Physiol Biochem 2018;50:1015 –1028 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
The Long Non-Coding RNA SNHG1 Attenuates Cell Apoptosis by Regulating miR-195 and BCL2-Like Protein 2 in Human Cardiomyocytes
Conclusion: Our results suggest a novel SNHG1/miR-195/BCL2L2 axis in the regulation of cardiomyocyte apoptosis. Modulation of SNHG1 may represent a novel strategy to treat cardiomyocyte apoptosis-related heart diseases.Cell Physiol Biochem 2018;50:1029 –1040 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
Combined Effect of IL-12R β2 and IL-23R Expression on Prognosis of Patients with Laryngeal Cancer
Conclusion: IL-12R β2 and IL-23R create a homeostasis within the tumor cells and TILs, and this homeostasis affects prognosis. While the intrinsic mechanisms of epigenetic immunoediting for IL-12Rβ2 and IL-23R remain unknown, additional larger and functional studies are warranted for validation.Cell Physiol Biochem 2018;50:1041 –1054 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research
