Cellular Physiology and Biochemistry 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Gastric Mammalian Target of Rapamycin Signaling Contributes to Inhibition of Ghrelin Expression Induced by Roux-En-Y Gastric Bypass
Conclusion: mTOR is therefore a gastric fuel sensor whose activity is linked to the regulation of ghrelin after Roux-en-Y Gastric Bypass.Cell Physiol Biochem 2018;51:664 –680 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
Curcumin Protects an SH-SY5Y Cell Model of Parkinson ’s Disease Against Toxic Injury by Regulating HSP90
Conclusion: Cur can effectively inhibit the toxic effect of MPP+ on SH-SY5Y cells and significantly reduce the adverse effects of MPP+ on dopaminergic neurons via up-regulation ofHSP90.Cell Physiol Biochem 2018;51:681 –691 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
MicroRNA-485 Modulates the TGF- β/ Smads Signaling Pathway in Chronic Asthmatic Mice by Targeting Smurf2
Conclusion: Overexpressed miR-485 inhibits cell proliferation and promotes apoptosis of ASMCs through the Smurf2-mediated TGF- β/Smads signaling pathway in mice with chronic asthma.Cell Physiol Biochem 2018;51:692 –710 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
miRNA-1290 Promotes Aggressiveness in Pancreatic Ductal Adenocarcinoma by Targeting IKK1
Conclusion: MiR-1290 may act as an oncogene by directly targeting the 3 ’-untranslated region of IKK1, and the miR-1290/IKK1 pathway may prove to be a novel diagnostic and therapeutic target for PDAC.Cell Physiol Biochem 2018;51:711 –728 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
Development of Inflammatory Immune Response-Related Drugs Based on G Protein-Coupled Receptor Kinase 2
G protein-coupled receptor kinase 2 (GRK2), as a vital Ser/Thr kinase, is an important regulatory protein in the inflammatory immune response (IIR) by maintaining the balance between the function of inflammatory immune cells and non-conventional inflammatory immune cells and regulating inflammatory immune cell infiltration, inflammatory cytokine secretion, and the signaling associated with endothelial function. However, the imbalance of GRK2 expression and activity plays an important role in the development of IIR-related diseases, such as hypertension, heart failure, Alzheimer ’s disease, type 2 diabetes mellitus, insul...
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
Osteogenic Effect of Inducible Nitric Oxide Synthase (iNOS)-Loaded Mineralized Nanoparticles on Embryonic Stem Cells
Conclusion: These findings suggest that iNOS-MNPs can induce osteogenic differentiation in ESCs by integrating complex signaling pathways.Cell Physiol Biochem 2018;51:746 –762 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
Galectin-3- Mediated Transdifferentiation of Pulmonary Artery Endothelial Cells Contributes to Hypoxic Pulmonary Vascular Remodeling
Conclusion: These results suggest that Gal-3 induces PAECs to acquire an α-SMA phenotype via a transdifferentiation process which depends on the activation of Jagged1/Notch1 pathways that mediate MyoD and SRF expression.Cell Physiol Biochem 2018;51:763 –777 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
miR-2954 Inhibits PI3K Signaling and Induces Autophagy and Apoptosis in Myocardium Selenium Deficiency
Conclusion: The expression of miR-2954 was increased in selenium-deficient myocardium, whereas overexpression of miR-2954 led to autophagy and apoptosis of myocardial cells during cardiac injury through regulation of the PI3K pathway; whether this phenomenon is a self-protection mechanism of the organism or damage caused by miR-2954 requires further study. Our findings provides new insight apoptosis in cardiomyocytes; additionally, we aim to provide a new direction for the diagnosis and targeted treatment of myocardial diseases.Cell Physiol Biochem 2018;51:778 –792 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
MicroRNA Quantitation During Dendritic Cell Endocytosis Using Imaging Flow Cytometry: Key Factors and Requirements
Conclusion: This method based on imaging flow cytometry provide an additional method to study miRNA processing in DCs, which makes it a valuable addition to existing miRNA research techniques.Cell Physiol Biochem 2018;51:793 –811 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
Catestatin Enhances Neuropathic Pain Mediated by P2X < sub > 4 < /sub > Receptor of Dorsal Root Ganglia in a Rat Model of Chronic Constriction Injury
Conclusion: Taken together, CST might boost NPP by enhancing the sensitivity of P2X4 receptors in the DRG of rats, which would provide us a novel perspective and research direction to explore new therapeutic targets for NPP.Cell Physiol Biochem 2018;51:812 –826 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 21, 2018 Category: Cytology Source Type: research
Vitamin K Supplementation Modulates Bone Metabolism and Ultra-Structure of Ovariectomized Mice
Conclusion: VK treatment in OVX mice exhibited beneficial effects on bone ultrastructure, mostly by altering osteoblastic function and secretion of organic bone matrix. Therefore, VK could be useful to treat osteopenic/osteoporotic patients.Cell Physiol Biochem 2018;51:356 –374 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 20, 2018 Category: Cytology Source Type: research
Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells
Conclusion: These findings suggest that SFN-NAC is a novel potential anti-glioma agent.Cell Physiol Biochem 2018;51:528 –542 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 20, 2018 Category: Cytology Source Type: research
miR-1-3p Contributes to Cell Proliferation and Invasion by Targeting Glutaminase in Bladder Cancer Cells
Conclusion: Taken together, these results demonstrated that miR-1-3p acts as a tumor suppressor via regulation of glutaminase expression in bladder cancer progression, and miR-1-3p might represent a novel therapeutic target for the treatment of bladder cancer.Cell Physiol Biochem 2018;51:513 –527 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 20, 2018 Category: Cytology Source Type: research
Taurolidine Sensitivity of Eryptosis, the Suicidal Erythrocyte Death
Conclusion: Taurolidine triggers cell shrinkage and phospholipid scrambling of the erythrocyte cell membrane, an effect at least in part due to Ca2+ entry and paralleled by increase of ceramide abundance.Cell Physiol Biochem 2018;51:501 –512 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 20, 2018 Category: Cytology Source Type: research
6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells
Conclusion: The identification of a broad inhibitory capacity of 6-PN and 8-PN for HDAC enzymes with antiproliferative effects on melanoma cells opens the perspective for clinical application as novel anti-melanoma drugs and the usage as innovative lead structures for chemical modification to enhance pharmacology or inhibitory activities.Cell Physiol Biochem 2018;51:543 –556 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - November 20, 2018 Category: Cytology Source Type: research
