Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09803-8. Online ahead of print.ABSTRACTThe ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of medicinal plants. There is however a major concern about the phyto-constituents in the plants that performs the healing function and the mechanism by which it works for different ailments are still a research prospect. Cardiometabolic disease (CMD) is no doubt becoming more frequent globally and this is due to poor approach in therapy, contrary effects linked with intensive control,...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: Cecilia Oluwamodupe Adesola Oluwaseun Adeleye Source Type: research
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF- β Signaling Pathway
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09799-1. Online ahead of print.ABSTRACTCartilage oligomeric matrix protein (COMP) regulates transforming growth factor-β (TGF-β) signaling pathway, which has been proved to be associated with skin fibrosis and pulmonary fibrosis. Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-β as well as their role in AF remains undefined. The purpose of this study is to clarify the role of COMP in AF and explore its potential mechanism. The hub gene of AF was identified from two datasets using bioinformatics. Fur...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: XiaoBi Cai Mingliang Li Ying Zhong Wenkun Yang Zhu Liang Source Type: research
Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09803-8. Online ahead of print.ABSTRACTThe ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of medicinal plants. There is however a major concern about the phyto-constituents in the plants that performs the healing function and the mechanism by which it works for different ailments are still a research prospect. Cardiometabolic disease (CMD) is no doubt becoming more frequent globally and this is due to poor approach in therapy, contrary effects linked with intensive control,...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: Cecilia Oluwamodupe Adesola Oluwaseun Adeleye Source Type: research
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF- β Signaling Pathway
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09799-1. Online ahead of print.ABSTRACTCartilage oligomeric matrix protein (COMP) regulates transforming growth factor-β (TGF-β) signaling pathway, which has been proved to be associated with skin fibrosis and pulmonary fibrosis. Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-β as well as their role in AF remains undefined. The purpose of this study is to clarify the role of COMP in AF and explore its potential mechanism. The hub gene of AF was identified from two datasets using bioinformatics. Fur...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: XiaoBi Cai Mingliang Li Ying Zhong Wenkun Yang Zhu Liang Source Type: research
Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09803-8. Online ahead of print.ABSTRACTThe ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of medicinal plants. There is however a major concern about the phyto-constituents in the plants that performs the healing function and the mechanism by which it works for different ailments are still a research prospect. Cardiometabolic disease (CMD) is no doubt becoming more frequent globally and this is due to poor approach in therapy, contrary effects linked with intensive control,...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: Cecilia Oluwamodupe Adesola Oluwaseun Adeleye Source Type: research
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF- β Signaling Pathway
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09799-1. Online ahead of print.ABSTRACTCartilage oligomeric matrix protein (COMP) regulates transforming growth factor-β (TGF-β) signaling pathway, which has been proved to be associated with skin fibrosis and pulmonary fibrosis. Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-β as well as their role in AF remains undefined. The purpose of this study is to clarify the role of COMP in AF and explore its potential mechanism. The hub gene of AF was identified from two datasets using bioinformatics. Fur...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: XiaoBi Cai Mingliang Li Ying Zhong Wenkun Yang Zhu Liang Source Type: research
Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09803-8. Online ahead of print.ABSTRACTThe ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of medicinal plants. There is however a major concern about the phyto-constituents in the plants that performs the healing function and the mechanism by which it works for different ailments are still a research prospect. Cardiometabolic disease (CMD) is no doubt becoming more frequent globally and this is due to poor approach in therapy, contrary effects linked with intensive control,...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: Cecilia Oluwamodupe Adesola Oluwaseun Adeleye Source Type: research
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF- β Signaling Pathway
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09799-1. Online ahead of print.ABSTRACTCartilage oligomeric matrix protein (COMP) regulates transforming growth factor-β (TGF-β) signaling pathway, which has been proved to be associated with skin fibrosis and pulmonary fibrosis. Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-β as well as their role in AF remains undefined. The purpose of this study is to clarify the role of COMP in AF and explore its potential mechanism. The hub gene of AF was identified from two datasets using bioinformatics. Fur...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: XiaoBi Cai Mingliang Li Ying Zhong Wenkun Yang Zhu Liang Source Type: research
Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09803-8. Online ahead of print.ABSTRACTThe ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of medicinal plants. There is however a major concern about the phyto-constituents in the plants that performs the healing function and the mechanism by which it works for different ailments are still a research prospect. Cardiometabolic disease (CMD) is no doubt becoming more frequent globally and this is due to poor approach in therapy, contrary effects linked with intensive control,...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: Cecilia Oluwamodupe Adesola Oluwaseun Adeleye Source Type: research
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF- β Signaling Pathway
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09799-1. Online ahead of print.ABSTRACTCartilage oligomeric matrix protein (COMP) regulates transforming growth factor-β (TGF-β) signaling pathway, which has been proved to be associated with skin fibrosis and pulmonary fibrosis. Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-β as well as their role in AF remains undefined. The purpose of this study is to clarify the role of COMP in AF and explore its potential mechanism. The hub gene of AF was identified from two datasets using bioinformatics. Fur...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: XiaoBi Cai Mingliang Li Ying Zhong Wenkun Yang Zhu Liang Source Type: research
Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09803-8. Online ahead of print.ABSTRACTThe ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of medicinal plants. There is however a major concern about the phyto-constituents in the plants that performs the healing function and the mechanism by which it works for different ailments are still a research prospect. Cardiometabolic disease (CMD) is no doubt becoming more frequent globally and this is due to poor approach in therapy, contrary effects linked with intensive control,...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: Cecilia Oluwamodupe Adesola Oluwaseun Adeleye Source Type: research
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF- β Signaling Pathway
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09799-1. Online ahead of print.ABSTRACTCartilage oligomeric matrix protein (COMP) regulates transforming growth factor-β (TGF-β) signaling pathway, which has been proved to be associated with skin fibrosis and pulmonary fibrosis. Atrial fibrosis is a major factor of atrial fibrillation (AF). Nevertheless, the interaction between COMP and TGF-β as well as their role in AF remains undefined. The purpose of this study is to clarify the role of COMP in AF and explore its potential mechanism. The hub gene of AF was identified from two datasets using bioinformatics. Fur...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: XiaoBi Cai Mingliang Li Ying Zhong Wenkun Yang Zhu Liang Source Type: research
Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
Cardiovasc Toxicol. 2023 Aug 7. doi: 10.1007/s12012-023-09802-9. Online ahead of print.ABSTRACTElectronic cigarette (EC) vaping is increasingly popular, despite growing evidence of adverse health effects. To further evaluate the impact of EC use on vascular health, we investigated the effects of brief EC inhalation on flow-dependent thrombus formation and microcirculation in healthy volunteers. The study was performed with a randomised double-blind crossover design. Twenty-two healthy subjects aged between 18 and 45 years with occasional tobacco use were recruited. Subjects inhaled 30 puffs of EC aerosol with and without n...
Source: Cardiovascular Toxicology - August 7, 2023 Category: Cardiology Authors: Gustaf Lyytinen Amelie Brynedal Erik Anes äter Lukasz Antoniewicz Anders Blomberg H åkan Wallén Jenny A Bosson Linnea Hedman Fariborz Mobarrez Sara Tehrani Magnus Lundb äck Source Type: research
Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
Cardiovasc Toxicol. 2023 Aug 7. doi: 10.1007/s12012-023-09802-9. Online ahead of print.ABSTRACTElectronic cigarette (EC) vaping is increasingly popular, despite growing evidence of adverse health effects. To further evaluate the impact of EC use on vascular health, we investigated the effects of brief EC inhalation on flow-dependent thrombus formation and microcirculation in healthy volunteers. The study was performed with a randomised double-blind crossover design. Twenty-two healthy subjects aged between 18 and 45 years with occasional tobacco use were recruited. Subjects inhaled 30 puffs of EC aerosol with and without n...
Source: Cardiovascular Toxicology - August 7, 2023 Category: Cardiology Authors: Gustaf Lyytinen Amelie Brynedal Erik Anes äter Lukasz Antoniewicz Anders Blomberg H åkan Wallén Jenny A Bosson Linnea Hedman Fariborz Mobarrez Sara Tehrani Magnus Lundb äck Source Type: research
Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
Cardiovasc Toxicol. 2023 Aug 7. doi: 10.1007/s12012-023-09802-9. Online ahead of print.ABSTRACTElectronic cigarette (EC) vaping is increasingly popular, despite growing evidence of adverse health effects. To further evaluate the impact of EC use on vascular health, we investigated the effects of brief EC inhalation on flow-dependent thrombus formation and microcirculation in healthy volunteers. The study was performed with a randomised double-blind crossover design. Twenty-two healthy subjects aged between 18 and 45 years with occasional tobacco use were recruited. Subjects inhaled 30 puffs of EC aerosol with and without n...
Source: Cardiovascular Toxicology - August 7, 2023 Category: Cardiology Authors: Gustaf Lyytinen Amelie Brynedal Erik Anes äter Lukasz Antoniewicz Anders Blomberg H åkan Wallén Jenny A Bosson Linnea Hedman Fariborz Mobarrez Sara Tehrani Magnus Lundb äck Source Type: research
