Biomechanics and Modeling in Mechanobiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Growth and remodeling of the dissected membrane in an idealized dissected aorta model
In conclusion, the model with the transient inflammation pattern allowed the reproduction of clinically observed dissected membrane thickening rates, diameter expansion rates and adaptations in microstructure, thus providing guidance in reducing the parameter space in growth and remodeling models of aortic dissections.PMID:37945985 | DOI:10.1007/s10237-023-01782-7 (Source: Biomechanics and Modeling in Mechanobiology)
Source: Biomechanics and Modeling in Mechanobiology - November 9, 2023 Category: Biomedical Science Authors: Lise Gheysen Lauranne Maes Nele Famaey Patrick Segers Source Type: research

Mechanical experimentation of the gastrointestinal tract: a systematic review
Biomech Model Mechanobiol. 2023 Nov 8. doi: 10.1007/s10237-023-01773-8. Online ahead of print.ABSTRACTThe gastrointestinal (GI) organs of the human body are responsible for transporting and extracting nutrients from food and drink, as well as excreting solid waste. Biomechanical experimentation of the GI organs provides insight into the mechanisms involved in their normal physiological functions, as well as understanding of how diseases can cause disruption to these. Additionally, experimental findings form the basis of all finite element (FE) modelling of these organs, which have a wide array of applications within medici...
Source: Biomechanics and Modeling in Mechanobiology - November 7, 2023 Category: Biomedical Science Authors: Ciara Durcan Mokarram Hossain Gr égory Chagnon Djordje Peri ć Edouard Girard Source Type: research

A new model for evaluating pressure-induced vascular tone in small cerebral arteries
Biomech Model Mechanobiol. 2023 Nov 4. doi: 10.1007/s10237-023-01774-7. Online ahead of print.ABSTRACTThe capacity of small cerebral arteries (SCAs) to adapt to pressure fluctuations has a fundamental physiological role and appears to be relevant in different pathological conditions. Here, we present a new computational model for quantifying the link, and its contributors, between luminal pressure and vascular tone generation in SCAs. This is assembled by combining a chemical sub-model, representing pressure-induced smooth muscle cell (SMC) signalling, with a mechanical sub-model for the tone generation and its transductio...
Source: Biomechanics and Modeling in Mechanobiology - November 5, 2023 Category: Biomedical Science Authors: Alberto Coccarelli Sanjay Pant Ioannis Polydoros Osama F Harraz Source Type: research

On the comparison between pre- and post-surgery nasal anatomies via computational fluid dynamics
Biomech Model Mechanobiol. 2023 Oct 30. doi: 10.1007/s10237-023-01776-5. Online ahead of print.ABSTRACTNasal breathing difficulties (NBD) are widespread and difficult to diagnose; the failure rate of their surgical corrections is high. Computational fluid dynamics (CFD) enables diagnosis of NBD and surgery planning, by comparing a pre-operative (pre-op) situation with the outcome of virtual surgery (post-op). An equivalent comparison is involved when considering distinct anatomies in the search for the functionally normal nose. Currently, this comparison is carried out in more than one way, under the implicit assumption th...
Source: Biomechanics and Modeling in Mechanobiology - October 30, 2023 Category: Biomedical Science Authors: Eric Segalerba Gabriele Dini Ciacci Maurizio Quadrio Jan O Pralits Source Type: research

Computational fluid dynamic modeling of the lymphatic system: a review of existing models and future directions
This article reviews existing computational fluid dynamic models of the lymphatics covering each structural component including the initial lymphatics, pre-collecting and collecting vessels, and lymph nodes. This is followed by a summary of limitations and gaps in existing computational models and reasons that development in this field has been hindered to date. Over the next decade, efforts to further characterize lymphatic anatomy and physiology are anticipated to provide key data to further inform and validate lymphatic fluid dynamic models. Development of more comprehensive multiscale- and multi-physics computational m...
Source: Biomechanics and Modeling in Mechanobiology - October 30, 2023 Category: Biomedical Science Authors: Tharanga D Jayathungage Don Soroush Safaei Gonzalo D Maso Talou Peter S Russell Anthony R J Phillips Hayley M Reynolds Source Type: research