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Buffy coat pooled platelet concentrate: A new age platelet component
CONCLUSIONS: Buffy coat pooled platelet has comparable and even better-quality control parameters (especially leukofiltered with PAS) than conventional platelet preparation and is a good alternative for meeting platelet transfusion requirements of critical patients during emergency hours in resource-constraint setting. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 1, 2021 Category: Hematology Authors: Rakesh Kumar Hari Krishan Dhawan Ratti Ram Sharma Jyotdeep Kaur Source Type: research

Impact of COVID-19 pandemic on the pattern of blood donation and blood safety: Experience from a hospital-based blood center in North India
CONCLUSION: COVID-19 pandemic has a significant impact on the pattern of blood donation and blood safety. Transfusion services must develop appropriate plans to respond efficiently to various challenges posed by such pandemics. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 1, 2021 Category: Hematology Authors: Singh Bharat Katharia Rahul Das Indraneel Srivastava Anubha Priyadarshi Atul Elhence Preeti Chaudhary Rajendra Source Type: research

COVID-19 pandemic preparedness of blood center
Kajal Khajuria, Kusum Thakur, Raman Sharma, Achchhar SinghAsian Journal of Transfusion Science 2021 15(1):117-118 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Kajal Khajuria Kusum Thakur Raman Sharma Achchhar Singh Source Type: research

Potential serological challenges caused by anti-IH antibody in the crossmatch laboratory
Manish Raturi, Shamee Shastry, Ganesh MohanAsian Journal of Transfusion Science 2021 15(1):115-116 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Manish Raturi Shamee Shastry Ganesh Mohan Source Type: research

Seroprevalence of cytomegalovirus among blood donors at a tertiary care hospital in Puducherry, India. Is testing donated blood for cytomegalovirus a viable option ?
Jayasree Cherukat, Sajini E Jacob, Rajendra Kulkarni, Abhishekh BasavarajegowdaAsian Journal of Transfusion Science 2021 15(1):113-114 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Jayasree Cherukat Sajini E Jacob Rajendra Kulkarni Abhishekh Basavarajegowda Source Type: research

A case report of multiple Rh alloantibodies in a pregnant female: Resolution by sequential adsorption
Divya Setya, Aseem K Tiwari, Dinesh Arora, Swati Pabbi Mehta, Geet AggarwalAsian Journal of Transfusion Science 2021 15(1):109-112Anti-G antibody mimics the reactivity pattern of coexistent anti-D and anti-C. Differentiating between the two is significant in antenatal females where the decision to administer RhD prophylaxis is based on the presence or absence of anti-D antibody. The aim of reporting this serological challenge is to emphasize the need for phenotyping red cells for sourcing appropriate in house red cell reagents and to help transfusion services sharpen problem-solving skills. A 26-year-old pregnant female wi...
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Divya Setya Aseem K Tiwari Dinesh Arora Swati Pabbi Mehta Geet Aggarwal Source Type: research

Just not cosmesis! Role of low-density lipoprotein apheresis in familial hypercholesterolemia: Experience at a newly developed tertiary care institution in Northern India
Daljit Kaur, Gita Negi, Rohit Walia, Sheetal Malhotra, Riti Bhatia, Sushant K Meinia, Saikat Mandal, Ashish JainAsian Journal of Transfusion Science 2021 15(1):104-108Familial hypercholesterolemia (FH) is characterized by an increase in plasma low-density lipoprotein-cholesterol (LDL-C) levels. It presents with tendon/skin xanthomas and premature atherosclerotic cardiovascular disease. The most available treatment options for FH are lipid-lowering medications such as statins, lifestyle modification, and LDL apheresis. As per American Society for Apheresis guidelines 2019, the treatment of FH using LDL apheresis falls under...
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Daljit Kaur Gita Negi Rohit Walia Sheetal Malhotra Riti Bhatia Sushant K Meinia Saikat Mandal Ashish Jain Source Type: research

A rare case of antibody against enhancement media interfering with crossmatching: A case report and review of literature
S Anuragaa, Dibyajyoti Sahoo, B Abhishekh, Revathy NairAsian Journal of Transfusion Science 2021 15(1):100-103Detection of clinically significant alloantibodies during pretransfusion testing is essential before any blood transfusion. Sometimes, clinically insignificant antibodies unrelated to blood group antigen may interfere with routine testing. Their interpretation is often made only after tedious immunohematology workup resulting in the exclusion of all possible clinically significant antibodies. We encountered such incidence which interfered with crossmatching. In our case, direct antiglobulin test was negative, indir...
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: S Anuragaa Dibyajyoti Sahoo B Abhishekh Revathy Nair Source Type: research

Is it an acute pain transfusion reaction ?
Remi Remakanth, B AbhishekhAsian Journal of Transfusion Science 2021 15(1):97-99A 40-year-old male patient presented to the emergency department with complaints of anasarca, mild dyspnea, orthopnea, vomiting, and decreased urine output. A provisional diagnosis of chronic kidney disease was made and planned for hemodialysis. In view of severe anemia, 1 packed red blood cell (PRBC) was requested and after pretransfusion testing one unit of buffy coat-poor, nonleucofiltered, coombs cross-match compatible, fresh (<7-days old) saline-adenine-glucose-mannitol PRBC unit was issued. After transfusion of around 20 ml of ...
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Remi Remakanth B Abhishekh Source Type: research

Red cell antibodies resulting in false-positive complement-dependent cytotoxicity cross-match: A unique case
Rajesh B Sawant, Sharad Sheth, Pooja Mehta, Deepali NakerAsian Journal of Transfusion Science 2021 15(1):94-96A false-positive complement-dependent cytotoxicity cross-match (CDC XM) has a negative impact in donor selection process obliterating healthy, donor compatible population. A 47-year-old male with chronic kidney disease was planned for ABO-compatible renal transplantation from his sister. CDC and donor-specific antibody (DSA) lysate XM were negative 10 days before transplant. The pretransplant CDC XM showed 40% positivity. DSA lysate XM and HLA antibody screen were negative. Patient's Indirect ...
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Rajesh B Sawant Sharad Sheth Pooja Mehta Deepali Naker Source Type: research

Extent of transfusion support in a developing country in managing a bleeding acute myeloid leukemia patient with platelet transfusion refractoriness
Gayathiri K Chellaiya, Chandran K Nair, Vineetha Raghavan, R Jesu Pandian, Roshan Vinod, Mohandoss MurugesanAsian Journal of Transfusion Science 2021 15(1):90-93Conventional platelet transfusion may not be adequate to deal with platelet transfusion refractoriness (PTR), and therefore human leukocyte antigen (HLA) or human platelet antigen (HPA) matched and platelet crossmatch compatible units are recommended. However, in developing countries, finding a unit that is HLA or HPA matched or platelet crossmatch poses a challenge. Hence, easier and cost-effective alternatives such as massive platelet transfusion and continuous p...
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Gayathiri K Chellaiya Chandran K Nair Vineetha Raghavan R Jesu Pandian Roshan Vinod Mohandoss Murugesan Source Type: research

& #8220;Auto-anti-A1 & #8221; in a healthy young blood donor: A rare cause of ABO discrepancy
Sudipta Sekhar Das, Rathindra Nath Biswas, Mahammad SafiAsian Journal of Transfusion Science 2021 15(1):87-89”Auto-anti-A1” has been sparsely discussed in the literature. Only few workers in the past depicted such antibody in transfused and nontransfused patients. The current case is probably the first example of auto-anti-A1 in a healthy young blood donor who was typed as ABO Group “A1B.” The cold reacting autoantibody in the donor was serologically characterized in details and was found to be nonhemolytic. ABO discrepancy was resolved and the donor was finally typed as ...
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Sudipta Sekhar Das Rathindra Nath Biswas Mahammad Safi Source Type: research

Postdonation information during dengue outbreaks at a single blood center in Brazil: An ally against transfusion-transmitted infections
Conclusion: The high number of recovered blood components due to PDI suggests that PDI remains a great ally in the fight against transfusion-transmitted infections and may be particularly useful during outbreaks of emerging potentially blood-borne pathogens. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Carolina Costa-Lima Bruno Deltreggia Benites Daniele Ramos Rocha Elisabete Andrade Patricia Alvarez Mariana Munari Magnus Marcelo Addas-Carvalho Source Type: research

Distribution of Kell antigens K, k, Kpa, and Kpb among blood donors in Jeddah city of Western Saudi Arabia
Conclusions: This study is the first report to determine the frequency of Kell antigens and phenotypes among blood donors in Jeddah city. These results appear to be useful in providing better care for patients by implementing tests that should become a routine in blood banks. The Kell system is very important in transfusion medicine practice. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Raed I Felimban Samaha M Sumeda Source Type: research

Evaluation of efficacy of Valsalva for attenuating needle puncture pain in first time nonremunerated voluntary plateletpheresis donors: A prospective, randomized controlled trial
Conclusions: Valsalva reduced both severity of venipuncture pain and anxiety. Valsalva can be performed by donors as it is an easy, painless, and nonpharmacological method of pain and anxiety attenuation. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 12, 2021 Category: Hematology Authors: Anubha Srivastava Sanjay Kumar Anil Agarwal Dheeraj Khetan Rahul Katharia Prabhaker Mishra Shikha Khati Sujeet Gautam Khuba Sandeep Source Type: research