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Outcome of 51 autologous peripheral blood stem cell transplants after uncontrolled-rate freezing ( & #8220;dump freezing & #8221;) using & #8722;80 & #176;C mechanical freezer
Conclusion: Our analysis shows that PBSC can be successfully cryopreserved with mechanical uncontrolled rate freezing. This is a cheap and simple method to freeze the stem cells for a short period in resource-constrained setting. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Rasika Dhawan Setia Satyam Arora Anil Handoo Dharma Choudhary Sanjeev Kumar Sharma Vipin Khandelwal Meenu Kapoor Shalu Bajaj Tina Dadu Gaurav Dhamija Virendra Bachchas Source Type: research

Experience of hepatitis C virus seroprevalence and its genomic diversity among transfusion-dependent thalassemia patients in a transfusion center
Conclusions: This study clearly indicates that the incidence of transfusion-transmitted hepatitis C is high in thalassemia patients, but actual scenario of HCV viremia can only be found by HCV RNA qualitative and quantitative detection method and not by ELISA, is a major concern for this high-risk group of population. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Kallol Kumar Bhattacharyya Aritra Biswas Debanjali Gupta Provash C Sadhukhan Source Type: research

Regenerative efficacy of therapeutic quality platelet-rich plasma injections versus phonophoresis with kinesiotaping for the treatment of chronic plantar fasciitis: A prospective randomized pilot study
Conclusion: Our study concluded that therapeutic quality autologous PRP injection (1x106 platelets/μl) has regenerative effect with long and better efficacy in pain management of chronic recalcitrant plantar fasciitis than Phonophoresis and Kinesiotaping. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Nitesh Gonnade Archana Bajpayee Abhay Elhence Vaibhav Lokhande Neeraj Mehta Manish Mishra Arunpreet Kaur Source Type: research

Immunohematological and clinical characterizations of mixed autoimmune hemolytic anemia
Conclusion: Patients with MAIHA often present with severe hemolysis necessitating blood transfusions. While red cells are coated with multiple autoantibodies, both warm reactive IgG and cold reactive IgM autoantibodies are present in the serum. These serological complexities not only render a crossmatch incompatibility but often lead to blood group discrepancy. “Best match” blood transfusion is always lifesaving. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Sudipta Sekhar Das Ritam Chakrabarty RU Zaman Source Type: research

Use of infusion pump for intrauterine transfusion: An effective hands-free transfusion circuit
Shamee Shastry, Karishma Ashwin Doshi, Vijayram Reddy Kankula, Pruthvi Raj GuduriAsian Journal of Transfusion Science 2018 12(2):97-98 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Shamee Shastry Karishma Ashwin Doshi Vijayram Reddy Kankula Pruthvi Raj Guduri Source Type: research

AJTS and it & #39;s legacy of knowledge
Jayashree SharmaAsian Journal of Transfusion Science 2018 12(2):95-96 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Jayashree Sharma Source Type: research

A curious case of thick white slick in a blood bag
Anju Dubey, Atul SonkerAsian Journal of Transfusion Science 2018 12(1):93-94 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Anju Dubey Atul Sonker Source Type: research

Detection of antibodies to co-trimoxazole (preservative drug) interfering with routine red cell antibody screening
We present a rare case of detection of anti-co-trimoxazole antibody during routine antibody screening in a female patient undergoing neurosurgery. These antibodies mimicked as antibody against high-frequency red cell antigens reacting in both saline phase as well as antiglobulin phase. Anti-co-trimoxazole antibody was confirmed by repeating antibody screen using reagent red cells of different manufacturers with and without co-trimoxazole drug as preservative as well as using washed red cell panels. There were no associated clinical or laboratory evidence of hemolysis. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Deepti Sachan S Aswin Kumar Source Type: research

Hemophagocytic lymphohistiocytosis in an infant with multiple triggers!!
We report a 9-month old infant who developed HLH in association with Stevens–Johnson syndrome following massive blood transfusion. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Sataroopa Mishra Amitabh Singh Lavleen Singh Anirban Mandal Rahul Jain Source Type: research

Anti Kpa alloantibody: Development of a rare alloantibody in a non-Hodgkin & #39;s lymphoma patient of Indian origin
We report an interesting case of Anti-Kpa in a 59-year-old female patient of Non-Hodgkin's Lymphoma, post radiotherapy, who first developed warm autoantibody and later developed anti-Kpa alloantibody on multiple transfusions. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Sadhana Mangwana Vivek Gangwar Source Type: research

Jehovah & #39;s Witness and consent for blood transfusion in a child: The Indian scenario
We present the case scenario of a child belonging to Jehovah's Witness denomination diagnosed with Burkitt lymphoma. His parents were in a dilemma whether to opt for blood transfusion or not. In the absence of laws and guidelines in this context, and considering the complications that he developed during the treatment period, it was very challenging for us to manage the situation both medically and medico-legally. This situation highlights the need for framing consensus guidelines/laws regarding elective blood transfusion in a minor to make health-care delivery, smooth, transparent and flawless. (Source: Asian J...
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: KG Gopakumar T Priyakumari Manjusha Nair P Kusumakumary Source Type: research

A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
Nirav Ramesh Dava, Alok Upadhyaya, Neha Agarwal, Amarjeet Mehta, Vijaypal Choudhary, Gourav GoyalAsian Journal of Transfusion Science 2018 12(1):75-77 We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3rd order male child of G3P3A0mother was admitted at 8th h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D antigen was positive in baby. Hematological parameters showed all the signs of ongoing hemolysis, and the bilirubin level was in the zone of exchange transfusion. Exchange transfusion wa...
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Nirav Ramesh Dava Alok Upadhyaya Neha Agarwal Amarjeet Mehta Vijaypal Choudhary Gourav Goyal Source Type: research

Relationship between T2 & #42; magnetic resonance imaging-derived liver and heart iron content and serum ferritin levels in transfusion-dependent thalassemic children
Conclusions: Serum ferritin cannot reliably predict the liver and heart iron content in Indian children with β thalassemia. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Kiran Suthar Vishnu Kumar Goyal Pramod Sharma Bindu Deopa Pradeep Singh Rathore Rama Krishan Bishnoi Source Type: research

Heterogeneity of O blood group in India: Peeping through the window of molecular biology
Conclusion: In the future, molecular genotyping of the ABO blood group system among different ethnic and tribal Indian groups would help in generating data to fill up the gaps in the molecular ABO map of the world. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Harita Gogri Sabita Ray Snehal Agrawal S Aruna Kanjaksha Ghosh Ajit Gorakshakar Source Type: research

Effect of plasma component transfusion on conventional coagulation screening tests
Conclusion: FFP transfusions as a prophylactic measure especially in patients with mildly deranged conventional coagulation screening tests without any empirical evidence of clinical bleeding needs further scrutiny. Reduction in INR following FFP transfusions was better in cohort having higher pre-transfusion INR value (> 3.0). (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Manish Raturi Shamee Shastry Mohandoss Murugesan Poornima B Baliga Kalyana Chakravarthy Source Type: research