A preliminary experience of plasma exchange in liver failure
CONCLUSION: PLEX may be effective in patients with ALF or ACLF. More data are needed to establish its role in the management of liver failure. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Himanshu Dandu Vivek Kumar Amit Goel Dheeraj Khetan Tulika Chandra Vipin Raj Bharti Source Type: research

Assessment of noncompliance in self-disclosure of deferrable risk behaviors among blood donors
CONCLUSION: Noncompliance in disclosure of high-risk behavior compromises blood safety. Blood donors must be ensured sufficient privacy while filling predonation questionnaire and while eliciting history any deferrable behaviors during blood donor medical examination. Privacy and confidence of the donors must be ensured either to share any postdonation information directly or anonymously to facilitate confidential unit exclusion. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Bala Vignesh Venkatachalam Ravindra Prasad Thokala Ashwin Anandan Krishnamoorthy Radhakrishnan Source Type: research

An insight to the internal quality control of blood components separated using the latest whole blood collection and processing systems: Experience from a tertiary care hospital blood transfusion service in Eastern India
CONCLUSION: We conclude that QC data generated in this study will provide invaluable information about the performance of the latest blood collection systems. QC of all blood components under study complied with both national and international standards. We opine that all blood centers should establish a complete QC program and adhere to departmental protocols and manufacturer's instructions for its execution and effective outcome. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Sudipta Sekhar Das Rathindra Nath Biswas Tirtha Pratim Sardar Mahammad Safi Source Type: research

Assessment of iron status in regular blood donors in a tertiary care hospital in Southern India
CONCLUSION: Our study found that regular blood donors had low iron stores, as shown by ferritin levels and other iron indicators. Using the current guidelines (hemoglobin >12.5 g/dL) for donation, or the red cell indices alone do not reflect the donor's actual iron status. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Joy Anju Basavarajegowda Abhishekh Basu Debdatta Zachariah Bobby Murali Sharan Source Type: research

Prozone phenomenon in pretransplant testing: An interesting conundrum involving solid-phase and cell-based assays
CONCLUSION: In our experimental findings, it was clear that cell-based assay (FCXM) was more severely affected by the prozone, whereas solid-phase (flow PRA) assay remained resistant to prozone. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Parvind Singh Aseem Kumar Tiwari Vikash Chandra Mishra Trupti Vimlakar Deshpande Pranav Dorwal Amit Kr Bhardwaj Sneha Kumari Vimarsh Raina Source Type: research

Factor assay in victims of snake bite: Experience from a tertiary care institute in South India
CONCLUSIONS: Early detection and treatment of envenomation remains the cornerstone of managing snake venom-induced consumptive coagulopathy. Anti-snake venom plays a major role in the reversal of coagulopathy. Blood and blood products would be useful when coagulopathy does not revert by ASV alone. Evidence-based transfusion can be implemented and cryoprecipitate may be used as many of the patients had factor XIII and fibrinogen deficiency as part of venom-induced coagulopathy. To improve patient management and thereby the outcome of patients CMEs and training programs for the treating physicians also has to be implemented ...
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Aboobacker Mohamed Rafi Susheela Jacob Innah Source Type: research

Distribution and frequency of principal Rh blood group antigens (D, C, c, E, and e) and their phenotypes in the blood donors attending blood bank in a tertiary care hospital in Barpeta district of Assam
CONCLUSION: D antigen is the most common antigen in our study population, whereas “e” antigen is the most common in most of the studies done from other parts of India. Data on frequencies of major Rh antigens in the local donor population will help in transfusing alloimmunized patients with corresponding antibody-negative blood ensuring blood safety. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Dipankar Baruah Gitali Devi Jabin Musfique Abhijit Bharali Umesh Chandra Dutta Source Type: research

Application of flow cytometry in transfusion medicine: The Sanjay Gandhi Post Graduate Institute of Medical Sciences, India experience
Rajendra Chaudhary, Sudipta Sekhar DasAsian Journal of Transfusion Science 2022 16(2):159-166The application of flow cytometry (FC) is diverse and this powerful tool in used in multiple disciplines such as molecular biology, immunology, cancer biology, virology, and infectious disease screening. FC analyzes a single cell or a particle very rapidly as they flow past single or multiple lasers while suspended in buffered solution. FC has a great impact in the field of transfusion medicine (TM) due to its ability to analyze individual cell population and cell epitopes by sensitive, reproducible, and objective methodologies. Th...
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Rajendra Chaudhary Sudipta Sekhar Das Source Type: research

Refrigerated centrifuge calibration for maximum platelet and plasma yield in a blood bank
R Loganathan, B AbhishekhAsian Journal of Transfusion Science 2022 16(1):156-157 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: R Loganathan B Abhishekh Source Type: research

AINT blood group: A case report on rare subtype of blood group A
Minal Wasnik, Saurabh Lahare, Ramesh Kumar Chandrakar, Sankalp SharmaAsian Journal of Transfusion Science 2022 16(1):154-155 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: Minal Wasnik Saurabh Lahare Ramesh Kumar Chandrakar Sankalp Sharma Source Type: research

Antihuman globulin test reactivity in SARS-CoV-2 infection-positive patients
Sheenam Thakkar, Swarupa Bhagwat, Jayashree SharmaAsian Journal of Transfusion Science 2022 16(1):152-153 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: Sheenam Thakkar Swarupa Bhagwat Jayashree Sharma Source Type: research

Prevalence of C, c, E, e, K, and k antigens in RhD-negative blood donors in and around Puducherry
Sridhar Gopal, Rajendra Kulkarni, Abhishekh BasavarajegowdaAsian Journal of Transfusion Science 2022 16(1):150-151 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: Sridhar Gopal Rajendra Kulkarni Abhishekh Basavarajegowda Source Type: research

Illustration: Thromboelastography & #8211; A useful tool to monitor COVID-19-associated coagulopathy
We present a case of COVID-19 in whom TEG was performed on admission and hypercoagulability was diagnosed and hence patient was started on Enoxaparin sodium 6000 IU twice daily. TEG was repeated after 5 days which showed normal coagulation status and the patient was discharged without any thrombotic complications. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: Ashwinkumar Vaidya Bemma Paonam Ganesh Mohan Shamee Shastry Source Type: research

Maternal allo anti-M antibody-induced hemolytic disease of newborn
Ashly Monson Mathew, Sangita Shah, Nidhi Bhatnagar, Mamta Shah, Tarak Patel, Truptee ThakkarAsian Journal of Transfusion Science 2022 16(1):144-147 Hemolytic disease of the fetus and newborn is a syndrome associated with immune destruction of the fetal and newborn red cells by maternal red cell alloantibodies. The detection of anti-M in antenatal screening can be responsible for neonatal red cell aplasia. A 32-h-old full-term neonate admitted with inconsolable cry and mild fever. Laboratory tests revealed progressive anemia and hyperbilirubinemia on day 3. The peripheral blood smear showed evidence of hemolysis and reticu...
Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: Ashly Monson Mathew Sangita Shah Nidhi Bhatnagar Mamta Shah Tarak Patel Truptee Thakkar Source Type: research

Effect of cryoprecipitate transfusion without ABO group consideration: A nightmare experience
Dibyajyoti Sahoo, Pragya SilwalAsian Journal of Transfusion Science 2022 16(1):140-143 The cryoprecipitate is an essential blood product as they are rich in factor VIII, fibrinogen, von Willebrand factor, factor XIII, and fibronectin, and their volume is too small. They play a significant role in the management of massive transfusion nowadays. Usually, they are used without ABO group consideration. We here report a case in which immunohematological problems arose due to out-of-group transfusion of cryoprecipitate. We suggest that the possibility of incompatibility subsequently is to be kept in mind during transfusion of l...
Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: Dibyajyoti Sahoo Pragya Silwal Source Type: research