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Patient outcome in antibody-positive systemic vasculitis treated with therapeutic plasma exchange
CONCLUSION: Favorable clinical outcomes were observed with TPE in patients with antibody-positive systemic vasculitis. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Aseem Kumar Tiwari Divya Setya Dhaval Tanna Dinesh Arora Geet Aggarwal Rajiva Gupta Shyam Bihari Bansal Sidharth Kumar Sethi Source Type: research

Role of therapeutic plasma exchange in rat killer (yellow phosphorous) poisoning
CONCLUSIONS: TPE could potentially bridge the gap between medical management and liver transplantation in cases of YP poisoning. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Krishnamoorthy Radhakrishnan Ravindra Prasad Thokala Ashwin Anandan Chandran Srinivasan Rengan Source Type: research

Impact of buffy coat reduction on the severity of febrile nonhemolytic transfusion reactions with red cell components
CONCLUSION AND SUMMARY: Leukoreduction remains the main modality to prevent FNHTR, but in developing countries like India, the use of buffy coat-depleted PRBC over PRBC can reduce the incidence and severity of FNHTR. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Lakhvinder Singh Nippun Prinja Ashish Jain Ratti Ram Sharma Neelam Marwaha Source Type: research

Comparative study of quality of leukoreduced packed red blood cell units as assessed by nageotte hemocytometry and flow cytometry
CONCLUSION: Flow cytometric technique provides a more precise and accurate objective tool compared to Nageotte hemocytometer which is labor intensive, time consuming, and prone to errors arising out of subjectivity along with reported underestimation bias. In the absence of adequate infrastructure, resources, and trained workforce, Nageotte hemocytometer method is a reliable alternative. Nageotte's chamber could be best used in the resource-constrained setup as it offers a relatively inexpensive, simple, and viable means to enumerate rWBCs. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Mohd Anas Sheikh Amit Kumar Biswas Ajay Kumar Baranwal Neerja Kushwaha Santosh Karade Joseph Philip Source Type: research

Autoantibodies mimicking alloantibodies: A case series unveiling the dilemmas of transfusion
CONCLUSION: Our case series highlights the importance of detecting the nature of the antibody whether it is alloantibody or autoantibody with antigen specificity. This would help in selecting appropriate antigen negative blood units for transfusion purpose. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Soma Agrawal Mohit Chowdhry Shiva Prasad Gajullupalli Muthukumaravel Source Type: research

A comparison of serological phenotyping and molecular genotyping for Kell, Kidd, and Duffy antigens in multi-transfused thalassemia patients
CONCLUSION: The actual antigen profile in multitransfused thalassaemia patients can be reliably determined using genotyping. This would benefit in providing better antigen matched transfusion therapy to such patients hence reducing the rate of alloimmunization. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Atul Sonker Anju Dubey Yatendra Mohan Source Type: research

Analysis of reasons of blood donor deferral at a tertiary care institute in India and its reflections on community health status
CONCLUSIONS: Our study results indicate that the blood donor deferral can have subtle variations based on regional aspects that should be considered when national policies are developed as pattern of deferral varies according to the epidemiology of diseases in different demographic areas. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Sheetal Malhotra Gita Negi Source Type: research

A prospective observational study to evaluate effect of heat inactivation on ABO titers performed by column agglutination technology and conventional tube technique
CONCLUSION: There is one log difference between median antibody titers estimated using heat inactivated and nonheat inactivated plasma. The use of HI for ABO isoagglutinin titer estimation can be considered in low resource settings. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Prashant Pandey Divya Setya Shweta Ranjan Mukesh Kumar Singh Source Type: research

Feasibility of high-yield plateletpheresis in routine practice: Experience from tertiary health center from South India
CONCLUSIONS: High-yield plateletpheresis can be done in routine practice with no added adverse donor reaction with effective quality products. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Dibyajyoti Sahoo Shahida Noushad Abhishekh Basavarajegowda Esha Toora Source Type: research

Von Willebrand factor levels in healthy blood donors and their association with blood group: A tertiary care hospital-based study
CONCLUSIONS: vWF level of donors ranged from 24 to 186 IU/dL with a mean of 96.31 IU/dL. Low vWF Ag level (below 50 IU/dl) was found in 2.5% of donors while 0.1% (2/2016) had level <30 IU/dL. O Rh (D)-positive blood group donors had the lowest vWF level (87.85 IU/dL), while ARh (D)-negative donors had the highest vWF level (117.27 IU/dL). fVIII level of the donor population ranged from 22% to 174%, with a mean of 98.82%. About 2.48% of donors had fVIII levels below 50%. There was a statistically significant correlation between fVIII lev...
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Nikita Agrawal Sangeeta Pahuja Sunita Sharma Source Type: research

Comparison of platelet indices in dengue fever patients based on platelet transfusion: A prospective observational study in a tertiary care center
CONCLUSIONS: PIs may act as a predictive tool in the diagnosis and predicting outcomes in dengue fever. Low platelet count and PCT, high PDW, MPV, PLCR, and IPF in transfused dengue patients were found to be statistically significant. Clinicians need to be sensitized about the utility and limitations of these indices and rationalize the need for red cell and platelet transfusions in dengue. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: J Asha Nithya M Baiju Susheela J Innah Aboobacker Rafi Bins M John Source Type: research

Structured feedback: A teaching and learning tool for the postgraduate medical students in transfusion medicine
CONCLUSION: Both the students as well as faculty were satisfied with the implementation of the feedback module in the department. Students reported awareness about the learning gaps, identification of appropriate study resources, and ample opportunity to interact with faculty, after taking the feedback sessions. The faculty felt satisfied on the acquisition of new skill for delivering structured feedback to students. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Daljit Kaur Gita Negi Ashish Jain Sushant Kumar Meinia Tanvir Kaur Sidhu Bharti Bhandari Rathore Source Type: research

Interesting rare case of polyarteritis nodosa related to hepatitis B virus and plasma exchange role ? & #8211; A case report and review of the literature
Parmatma Prasad Tripathi, Ratti Ram Sharma, Chirag R Kopp, Amal Basnet, Sharanya Ramakrishnan, Divjot Singh Lamba, Rekha Hans, Aman SharmaAsian Journal of Transfusion Science 2023 17(1):7-12 Immune-mediated diseases wherein immune complex-mediated injury is predominant; plasma exchange remains a therapeutic option for vasculitis. Hepatitis B virus-associated polyarteritis nodosa (HBV-PAN) wherein immunosuppressants can be contraindicated, plasma exchanges have a proven role when combined with antiviral therapy. Plasma exchange by hastening the clearance of immune complexes is beneficial in acute organ dysfunction. A 25-ye...
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Parmatma Prasad Tripathi Ratti Ram Sharma Chirag R Kopp Amal Basnet Sharanya Ramakrishnan Divjot Singh Lamba Rekha Hans Aman Sharma Source Type: research

Establishment of normal reference range of serum hepcidin in Indian blood donors
CONCLUSION: These findings suggest that further studies with larger groups of donors are mandatory to produce reference values of hepcidin that can be précised to the whole populace in India. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - March 1, 2023 Category: Hematology Authors: Ashutosh Singh Hem Chandra Pandey Rajendra Chaudhary Source Type: research

The prevalence of Dia, Mia, and Mur antigens among Malaysians and Indians
Isha Polavarapu, Shamee ShastryAsian Journal of Transfusion Science 2022 16(2):287-288 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - November 12, 2022 Category: Hematology Authors: Isha Polavarapu Shamee Shastry Source Type: research