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Use of & #8220;smartphone & #8221; technology for managing workload in transfusion-transmissible infection (nucleic acid testing) laboratory for platelet concentrate inventory management resulting in timely issue of platelets: Experience from a tertiary care center
Rekha Hans, Suresh Sharma, Neelam Marwaha, Suchet Sachdev, Hari Krishan Dhawan, Ashish Jain, Ratti Ram SharmaAsian Journal of Transfusion Science 2017 11(2):217-218 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Rekha Hans Suresh Sharma Neelam Marwaha Suchet Sachdev Hari Krishan Dhawan Ashish Jain Ratti Ram Sharma Source Type: research

Hello & #8230;. there is a blob of quark in my cryo bag!!
Atul Sonker, Anju Dubey, Rajendra ChaudharyAsian Journal of Transfusion Science 2017 11(2):215-216 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Atul Sonker Anju Dubey Rajendra Chaudhary Source Type: research

Adding up the evidence: Trigger for prophylactic plasma transfusion
Manish Raturi, Shamee Shastry, Poornima B BaligaAsian Journal of Transfusion Science 2017 11(2):214-215 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Manish Raturi Shamee Shastry Poornima B Baliga Source Type: research

HIV risk associated with nucleic acid testing tested seronegative blood donation where the donor was not preassessed for the risk
Kanjaksha Ghosh, Kanchan MisraAsian Journal of Transfusion Science 2017 11(2):213-214 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Kanjaksha Ghosh Kanchan Misra Source Type: research

Out of the blue: Blue blood.!
Lenin Babu Elakkumanan, Jayasree Cherukat, Jane Nithya Tolson, Sarath Sistla, Abhishekh BasavarajegowdaAsian Journal of Transfusion Science 2017 11(2):212-212 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Lenin Babu Elakkumanan Jayasree Cherukat Jane Nithya Tolson Sarath Sistla Abhishekh Basavarajegowda Source Type: research

Interference of daratumumab with pretransfusion testing, mimicking a high-titer, low avidity like antibody
We present a case that demonstrates daratumumab could mimic a high titer low avidity (HTLA) alloantibody. A 34-year-old male patient of refractory myeloma was recruited in phase three clinical trial involving daratumumab. Samples were sent to the blood bank for pretransfusion testing. Without knowledge of patient having used daratumumab, we mistook the reactivity in the patient's sera as an HTLA antibody due to the results of negative autocontrol and high titers of antibody activity. Antibody screen showed a panreactive pattern and the reactivity against screening cells was up to a titer of 1: 1240. The reactivity was ...
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Mei-Hwa Lin Fei-Yun Liu Hsiu-Mien Wang Hsin-Ching Cho Shyh-Chyi Lo Source Type: research

Daily plasma exchange in severe Guillain & #8211;Barr & #233; syndrome helps in early weaning from ventilator: A lesson from a case
Arunpreet Kaur, Archana Bajpayee, Nitin Kumar Bajpai, Nikhil KothariAsian Journal of Transfusion Science 2017 11(2):206-208Intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE) are well-known therapeutic modalities in Guillain–Barré syndrome (GBS). In developing countries like India, where plasma-derived products (IVIG) are not easily available, and affordable TPE is preferred. Here, we reported a case of severe GBS, who was treated with daily plasma exchange (PLEX) rather than recommended alternate day schedule. A 16-year-old male adolescent of severe GBS, i.e., on mechanical ventilator was tr...
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Arunpreet Kaur Archana Bajpayee Nitin Kumar Bajpai Nikhil Kothari Source Type: research

Acute respiratory distress syndrome in a neonate due to possible transfusion-related acute lung injury
We report a case of TRALI in a preterm neonate developing acute respiratory distress within 6 h of blood product transfusion in the absence of preexisting lung disease. Prompt ventilator and supportive management were instituted. The baby showed clinical and radiological improvement within 12 h; however, he succumbed to death due to acute massive pulmonary hemorrhage 36 h later. Possibility of TRALI should be kept if there is sudden deterioration of lung function after blood transfusion. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Arti Maria Sheetal Agarwal Anu Sharma Source Type: research

Coinheritance of hemoglobin D-Punjab and & #946;0-thalassemia 3.4 kb deletion in a Thai girl
Sitthichai Panyasai, Sarinna Rahad, Sakorn PornprasertAsian Journal of Transfusion Science 2017 11(2):199-202Hemoglobin (Hb) D-Punjab [β 121(GH4) Glu→ln; HBB: C.364G>C] and β0-thalassemia 3.4 kb deletion are very rare in the Thai population. For the first time, the coinheritance of HbD-Punjab with β0-thalassemia 3.4 kb deletion was reported in a 7-year-old Thai girl. She had mild anemia (Hb 115.0 g/L and mean corpuscular hemoglobin 18.1 pg) with red blood cell microcytosis (mean corpuscular volume 52.5 fL). By capillary electrophoresis (CE), HbD-Punjab was found at a migration position of 180 s wit...
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Sitthichai Panyasai Sarinna Rahad Sakorn Pornprasert Source Type: research

Autoimmune hemolytic anemia caused by anti & #8220;e & #8221;: A challenge: A case report with review of literature
Sangeeta Pahuja, Deepti VermaAsian Journal of Transfusion Science 2017 11(2):195-198Autoimmune hemolytic anemia (AIHA) is featured by short red cell survival due to autoantibodies. AIHA caused by anti 'e' is a tough clinical situation as antigen 'e' is a highly prevalent antigen. The present case highlights the same and different issues related to it. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Sangeeta Pahuja Deepti Verma Source Type: research

Successful surgical procedure in a patient of aplastic anemia with platelet refractoriness, using cross-match compatible platelets
Ritam Chakrabarty, Sudipta Sekhar DasAsian Journal of Transfusion Science 2017 11(2):192-194This case marks the beginning of issuing cross-matched platelet products in Eastern India. A known case of aplastic anemia, on regular transfusion support, now presented with obstructed ventral periumbilical hernia requiring urgent surgical intervention. Platelet count at presentation was 13,000/μL. Platelet cross-matching was done by solid phase method. Ten units of random donor platelets were crossmatched. Five units were compatible and transfused. Counts rose to 84,000/μL after 1 h. Surgery was completed successfully. T...
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Ritam Chakrabarty Sudipta Sekhar Das Source Type: research

The prozone effect exerted by the complement-binding anti-Lea on anti-D
Conclusion: An anti-D showed prozone effect exerted by the complement-fixing anti-Lea in the test. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Sanmukh R Joshi Kamlesh H Parekh Source Type: research

Transfusion-related adverse reactions in pediatric and surgical patients at a tertiary care teaching hospital in India
Conclusion: Transfusion reactions in children and surgical patients are commonly observed with cellular blood components. Majority of reactions are acute and nonserious. FNHTRs and allergic reactions are the most common transfusion reactions. Risk of transfusion reactions is more in patients receiving multiple transfusions. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Kunal J Ghataliya Jigar D Kapadia Mira K Desai KM Mehariya GH Rathod Nidhi Bhatnagar MD Gajjar Source Type: research

Detection of T and B cells specific complement-fixing alloantibodies using flow cytometry: A diagnostic approach for a resource limited laboratory
Conclusions: We postulate that this method incorporates most of the features of all the available modalities (i.e., National Institute of Health-complement dependent lymphocytotoxicity, FCXM, cytotoxic FCXM and C4d-flowPRA) yet cost-effective and best suited for resource-limited laboratory/ies which is a common scenario in developing countries. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Dharmendra Jain Pranav Dorwal Amit Pande Neetu Tyagi Simmi Mehra Vimarsh Raina Source Type: research

Knowledge and attitude of donating and using cord blood for transfusion among patients attending Nnamdi Azikiwe University Teaching Hospital, Nnewi, South East Nigeria
Conclusion: The knowledge and acceptance of UCB for transfusion are low in our environment. However, proper counseling and public enlightenment could change this attitude. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Chide E Okocha Nkiru N Ezeama John C Aneke Chinyere U Onubogu Charles I Okafor Chijioke G Egbunike Source Type: research

Therapeutic leukocyte reduction for acute and chronic myeloid leukemias: A 4-year experience from an oncology center in India
Conclusion: TLR is a safe and effective therapy for leukoreduction in hematological malignancies in our experience. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Anita A Tendulkar Puneet A Jain Abhaykumar Gupta Nidhi Sharma Anisha Navkudkar Vijaya Patle Source Type: research

Insight into donor deferral pattern based on peripheral blood counts: An experience from South Pakistan
Conclusion: A high prevalence of anemia among blood donors signifies deteriorating health status not only in donor population but also in general population. This situation calls for more concerted efforts as otherwise it would lead to decreased blood donor pool. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Sadia Sultan Syed Mohammed Irfan Mohammad Amjad Baig Syed Mohammad Usman Umme Aiman Shirazi Source Type: research

Rapid dry plasma thawing system: An alternative to conventional thawing baths
Conclusion: Plasmatherm II can be a good alternative to water bath to rapidly thaw FFPs by preserving coagulation factors and eliminating the risk of bacterial contamination. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: S Sanooja Pinki Ganesh Mohan Aboobacker Mohamed Rafi Susheela Jacob Innah Tom Thomas Source Type: research

Comparison of two algorithms to confirm and discriminate samples initially reactive for nucleic acid amplification tests
Conclusion: The study data suggest that replicate testing strategy and Ultrio Plus reduce the number of “inconclusive results” seen with earlier commonly used algorithm. We recommend a replicate testing strategy in ID-NAT testing since it will increase the DY and will eliminate the unnecessary discriminatory tests. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Aseem Kumar Tiwari Ravi C Dara Dinesh Arora Geet Aggarwal Ganesh Rawat Vimarsh Raina Source Type: research

Evaluation of process excellence tools in improving donor flow management in a tertiary care hospital in South India
Conclusion: Process Excellence is not a programme; it's a culture that transforms an organization and improves its Quality and Efficiency through new attitudes, elimination of wastes and reduction in costs. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Divya Venugopal Aboobacker Mohamed Rafi Susheela Jacob Innah Bibin T Puthayath Source Type: research

Comparison of antibody titers using conventional tube technique versus column agglutination technique in ABO blood group incompatible renal transplant
Conclusion: The column agglutination method for anti A/B titer estimation in an ABO incompatible kidney transplant is more sensitive, with the column agglutination results being approximately two and half fold higher (one more dilution) than that of tube method. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Amit Bhangale Amardeep Pathak Smita Pawar Tarun Jeloka Source Type: research

Dedicated donor unit transfusions reduces donor exposure in pediatric surgery patients
Conclusion: Our study showed that by practicing dedicated donor unit transfusion policy, for neonates undergoing surgery we could significantly reduce the donor exposure. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Satyam Arora Neelam Marwaha Hari Krishan Dhawan K. L. N. Rao Source Type: research

INRA, a new high-frequency antigen in the INDIAN (IN023) blood group system
Conclusion: The antibody to enzyme sensitive HFA was tested for serological and molecular genetics studies and found to be directed to the novel HFA, named as INRA of the INDIAN blood group system and was assigned a numerical symbol IN: 005 by the International Society of Blood Transfusion (ISBT). (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Sanmukh R Joshi Ankita Sheladiya Kinjal V Mendapara-Dobariya Source Type: research

Red cell alloimmunization in repeatedly transfused patients
Conclusions: Alloantibodies should be identified in repeatedly transfused patients and should be given corresponding antigen negative blood unit which will minimize the antibody mediated destruction of transfused red cells. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Dimel K Bhuva Jitendra H Vachhani Source Type: research

Compliance score as a monitoring tool to promote treatment adherence in children with thalassemia major for improved physical growth
Conclusion: This paper brings out a simple, regularly monitored scoring system to promote growth in thalassemia children through improved compliance to treatment, which incentivized them to maintain or improve their scores for better height velocity and weight gain. No such compliance score has been tabulated for thalassemia patients as of date. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Sarala Kannan Amarjeet Singh Source Type: research

Role of low plasma volume treatment on clinical efficacy of plasmapheresis in neuromyelitis optica
Conclusions: Plasmapheresis is a safe and efficient add-on therapy in NMO, especially in steroid-resistant cases. Although the volumes of plasma treated during acute plasmapheresis were less than recommended minimum volumes, majority of patients had significant clinical improvement. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Akshay Batra Sundar Periyavan Source Type: research

Factors influencing transfusion requirement in patients undergoing first-time, elective coronary artery bypass graft surgery
Conclusions: By stratifying patients according to their risk factor for red cell transfusion, the high-risk patients could be recognized and should be enrolled into effective patient blood management program to minimize their risk of exposure to allogeneic blood transfusion. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Ailin Mazuita Mazlan Yasmin Ayob Abd Rahim Hussein Thiru Kumar Namasiwayam Wan Mohd. Zahiruddin Wan Mohammad Source Type: research

Effectiveness of team-based learning methodology in teaching transfusion medicine to medical undergraduates in third semester: A comparative study
Conclusions: The mean of student scores by didactic, Individual Readiness Assurance Test (score “A”), and overall (score “D”) was 49.8% (standard deviation [SD]-14.8), 65.6% (SD-10.9), and 65.6% (SD-13.8), respectively. The study showed positive educational outcome in terms of knowledge acquisition, participation and engagement, and team performance with TBL. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Neena Piyush Doshi Source Type: research

Extracorporeal photopheresis: Review of technical aspects
Satyam Arora, Rasika SetiaAsian Journal of Transfusion Science 2017 11(2):81-86Extracorporeal photochemotherapy (ECP) is considered as an immune modulating therapy majorly targeting the T cells of the Immune system. ECP induces an anti-inflammatory condition with tolerogenic responses without inducing a global immunosuppression state which is a typical feature of other therapeutic options such as steroids. Clinical indication of ECP has grown over time since its initial applications. Our review discusses the technical aspects of the concept of photopheresis with the available methods for its clinical applications. (Source:...
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Satyam Arora Rasika Setia Source Type: research

Hemolysis during component preparation: An inadvertent cause
Puneet Sachdeva, Anubhav Gupta, Hari Krishan Dhawan, Ratti Ram Sharma, Neelam MarwahaAsian Journal of Transfusion Science 2017 11(2):79-80 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Puneet Sachdeva Anubhav Gupta Hari Krishan Dhawan Ratti Ram Sharma Neelam Marwaha Source Type: research

A handy chart for the interpretation of sequential differential adsorption & #8211;elution procedure
Shamee Shastry, Soumya DasAsian Journal of Transfusion Science 2017 11(2):77-78 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - September 11, 2017 Category: Hematology Authors: Shamee Shastry Soumya Das Source Type: research

A case of anemia: How important is peripheral blood film before transfusing ?
Pankaj Kumar, Geetanjali Jindal, Vishal GuglaniAsian Journal of Transfusion Science 2017 11(1):75-76 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Pankaj Kumar Geetanjali Jindal Vishal Guglani Source Type: research

Median channel shift less than the cutoff in flow cytometric crossmatch: Not to be ignored & #33;
Pranav Dorwal, Shyam Bihari Bansal, Rajni Chauhan, Dharmendra Jain, Vimarsh Raina, Vijay KherAsian Journal of Transfusion Science 2017 11(1):73-75 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Pranav Dorwal Shyam Bihari Bansal Rajni Chauhan Dharmendra Jain Vimarsh Raina Vijay Kher Source Type: research

Chemiluminescence brings renaissance in TTI screening: Primi experientia
Diptiranjan Rout, Rahul Chaurasia, Poonam Coshic, Kabita ChatterjeeAsian Journal of Transfusion Science 2017 11(1):72-73 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Diptiranjan Rout Rahul Chaurasia Poonam Coshic Kabita Chatterjee Source Type: research

Knowledge and practice of biosafety precautions in a developing tertiary care institute of North India
Anju Dubey, Atul SonkerAsian Journal of Transfusion Science 2017 11(1):70-71 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Anju Dubey Atul Sonker Source Type: research

Should we reconsider platelet content criteria for single donor platelets in West Bengal, India ?
Rizwan Javed, Sabita BasuAsian Journal of Transfusion Science 2017 11(1):69-70 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Rizwan Javed Sabita Basu Source Type: research

Therapeutic leukapheresis in a tertiary care hospital: A case series
Raj Nath Makroo, Brinda Kakkar, Mohit Chowdhry, Soma Agrawal, Shishir Seth, Uday K ThakurAsian Journal of Transfusion Science 2017 11(1):65-68Patients presenting with hyperleukocytosis secondary to acute leukemia, with total leukocyte count or blast count more than 100,000/μL are often considered for leukapheresis, especially if clinical signs of leukostasis are present. Leukostasis is often associated with high morbidity and mortality in patients with leukemic processes. The main goal of management of hyperleukocytosis and/or leukostasis is to reduce the blast count before initiation of chemotherapy. Leukapheresis is...
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Raj Nath Makroo Brinda Kakkar Mohit Chowdhry Soma Agrawal Shishir Seth Uday K Thakur Source Type: research

Anti-G with concomitant anti-C and anti-D: A case report in a pregnant woman
This report disseminates knowledge on identification of anti-G and its importance in pregnant women. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Rabeya Yousuf Ahmad Nasirudin Mustafa Siew-Ling Ho Yee-Loong Tang Chooi-Fun Leong Source Type: research

Low-density lipoprotein apheresis in a pediatric patient of familial hypercholesterolemia: Primi experientia from a tertiary care center in North India
Kanchan Dogra, Alpesh Goyal, Rajesh Khadgawat, Yashdeep Gupta, Diptiranjan Rout, Parag Prabhakar Fulzele, Rahul Chaurasia, Poonam Coshic, Kabita ChatterjeeAsian Journal of Transfusion Science 2017 11(1):58-61Familial hypercholesterolemia (FH) is an autosomal dominant disorder due to mutation of apolipoprotein-B receptor gene causing severe dyslipidemia. Lifestyle modification and medical treatment attenuate the disease progression, but as these fail to control the blood cholesterol levels, low-density lipoprotein (LDL) apheresis comes forth as a treatment option. To the best of our knowledge, the following is the very firs...
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Kanchan Dogra Alpesh Goyal Rajesh Khadgawat Yashdeep Gupta Diptiranjan Rout Parag Prabhakar Fulzele Rahul Chaurasia Poonam Coshic Kabita Chatterjee Source Type: research

Alloimmunization in autoimmune hemolytic anemia patient: The differential adsorption approach
In this report, we present our approach in a thalassemia patient who presented with warm-type autoimmune hemolytic anemia, low hemoglobin of 5.8 g/dl, and three significant alloantibodies (anti-D, anti-S, and anti-Jk b) which were masked by pan-reactive warm autoantibody(s). Differential adsorption was used to unmask underlying alloantibodies. We suggest that differential adsorption procedure is an effective and efficient method for autoantibody adsorption, detection, and identification of masked alloantibody(s), especially in patients with low hemoglobin and history of recent blood transfusion. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Ravi C Dara Aseem Kumar Tiwari Dinesh Arora Subhasis Mitra Devi Prasad Acharya Geet Aggarwal Jyoti Sharma Source Type: research

Snake in the grass: A case report of transfusion reactions due to contaminated donor arm disinfectant
Anju Dubey, Atul Sonker, Rajendra ChaudharyAsian Journal of Transfusion Science 2017 11(1):50-52Bacterial contamination of blood components remains an on-going challenge. In the majority of cases, organisms contaminating the blood components are a part of normal skin flora. Here, we report a case of bacterial contamination of blood units through contaminated donor arm disinfectant. There was a series of reactions due to random donor platelet (RDP) transfusion. The patients had features of septic transfusion reactions. On root cause analysis, spirit swabs used for disinfection of donors' arm were identified as the culpr...
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Anju Dubey Atul Sonker Rajendra Chaudhary Source Type: research

ABO incompatible renal transplant: Transfusion medicine perspective
Conclusion: With an average of 4-5 TPE procedures pretransplant and 2-3 TPE procedures post transplants, ABO incompatible renal transplantations can be successfully accomplished. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Raj Nath Makroo Sweta Nayak Mohit Chowdhry Sanjiv Jasuja Gaurav Sagar NL Rosamma Uday Kumar Thakur Source Type: research

First Indian study to establish safety of immediate-spin crossmatch for red blood cell transfusion in antibody screen-negative recipients
Conclusion: In AS-negative patients, IS crossmatch is as safe as conventional AHG crossmatch and can, therefore, replace conventional AHG crossmatch protocol. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Aseem Kumar Tiwari Geet Aggarwal Ravi C Dara Dinesh Arora Gautam Kumar Gupta Vimarsh Raina Source Type: research

Factors affecting the quality of cryoprecipitate
Conclusion: The factor VIII recovery in CRYO improves significantly with higher baseline factor VIII: C levels, blood group A donor, and rapid freezing using blast freezer. Rapid freezing also increases the fibrinogen yield. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Rajeswari Subramaniyan Neelam Marwaha Ashish Jain Jasmina Ahluwalia Source Type: research

A comparative study showing the potency of anti-C3d and anti-immunoglobulin G in polyspecific anti-human globulin using fresh and cryopreserved red blood cells
Conclusion: This result suggests that the sensitization of fresh RBCs with IgG and C3d is not affected by using cryopreserved cells for 30 days. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Kanchan Ahuja Ranjan Kumar Satapathy Garima Gulati Surinder Singh Source Type: research

Antibody titers in Group O platelet donors
Conclusion: Microplate can be used to perform titers in resource-constrained settings. Screening for critical titers in O group donors is essential as they are more implicated in hemolytic transfusion reactions. In the absence of a global consensus on this topic, institutes may need to formulate their own guidelines on handling ABO plasma-incompatible PLT transfusions. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Anita Amar Tendulkar Puneet Ashok Jain Sanjay Velaye Source Type: research

Delta check for blood groups: A step ahead in blood safety
Conclusion: Delta checks proved to be an effective tool for detecting blood group errors and prevention of accidental mismatched blood transfusions. Preanalytical errors in patient identification or sample labeling were the most frequent. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Raj Nath Makroo Aakanksha Bhatia Source Type: research

Comparison of deferasirox and deferoxamine effects on iron overload and immunological changes in patients with blood transfusion-dependent & #946;-thalassemia
Conclusion: This study indicated that deferasirox is more effective than deferoxamine regarding the iron overload but not in the immunological profile in patients with blood transfusion-dependent β-thalassemia. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Hayder M Al-Kuraishy Ali I Al-Gareeb Source Type: research

Reporting adverse transfusion reactions: A retrospective study from tertiary care hospital from New Delhi, India
Conclusions: Awareness should be increased among clinicians to correctly prevent, identify, and report transfusion-related adverse events. These measures should be implemented to increase blood transfusion quality and safety. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: Sangeeta Pahuja Vandana Puri Gunjan Mahajan Prajwala Gupta Manjula Jain Source Type: research

Blood transfusion safety; current status and challenges in Nigeria
John C Aneke, Chide E OkochaAsian Journal of Transfusion Science 2017 11(1):1-5The attainment of blood transfusion safety in Nigeria (and probably the rest of Sub-Saharan Africa) remains an uphill task due to a number of factors, ranging from shortage of blood, poor implementation of blood transfusion guidelines, infrastructural deficits to high prevalence of transfusion-transmissible infections (TTIs), particularly hepatitis and human immune deficiency viruses. We reviewed available data on blood transfusion practices and safety in Nigeria using the PubMed, PubMed Central, Google Scholar, and African Index Medicus search ...
Source: Asian Journal of Transfusion Science - February 21, 2017 Category: Hematology Authors: John C Aneke Chide E Okocha Source Type: research