Hemolytic events during therapeutic plasma exchange: Root cause analysis
Sachan Deepti, Saha Suryatapa, Kaliamoorthy Ilankumaran, Rela MohamedAsian Journal of Transfusion Science 2019 13(1):76-78 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Sachan Deepti Saha Suryatapa Kaliamoorthy Ilankumaran Rela Mohamed Source Type: research

Successful therapeutic plasma exchange in a patient with Morvan syndrome
Rounak Dubey, Rajeev S Mallhi, Bhushan Asthana, Neerja Kushwaha, Arvind YadavAsian Journal of Transfusion Science 2019 13(1):73-75Morvan syndrome is a rare autoimmune disorder, characterized by hyperexcitability of both central and peripheral nervous systems, accompanied by autonomic dysfunction and hallucinations.[1] Therapeutic plasma exchange (TPE) has been found to be an effective mode of treatment for this disease, but there is limited literature supporting the same.[2] A 26-year-old male was admitted to our hospital and diagnosed with a case of Morvan syndrome, based on the clinical picture and laboratory findings. W...
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Rounak Dubey Rajeev S Mallhi Bhushan Asthana Neerja Kushwaha Arvind Yadav Source Type: research

Critical evaluation of donor direct antiglobulin test positivity: Implications in cross-matching and lessons learnt
We report two cases of DAT positive donors with no clinical or laboratory evidence of hemolysis. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Vandana Puri Aruna Chhikara Geetika Sharma Shivali Sehgal Sunita Sharma Source Type: research

Successful treatment of Sezary syndrome with extracorporeal photopheresis & #8211; The first attempt in India
Aseem K Tiwari, Dinesh Arora, Pratibha Dhiman, Sheilly Kapoor, Geet Aggarwal, Ravi C Dara, Ashok VaidAsian Journal of Transfusion Science 2019 13(1):66-69Sezary syndrome (SS) is more aggressive leukemic variant of cutaneous T-cell lymphoma in which a significant number of circulating malignant (Sezary) cells are observed in peripheral blood. Although single-agent or combination chemotherapy regimens have produced moderately high response rates in patients with advanced-stage SS, these responses are invariably not durable. Extracorporeal photopheresis (ECP) is recommended as an immunomodulator treatment, offering better lif...
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Aseem K Tiwari Dinesh Arora Pratibha Dhiman Sheilly Kapoor Geet Aggarwal Ravi C Dara Ashok Vaid Source Type: research

Intraoperative acute hematuria: Sole clue to mismatch transfusion
Priya Rudingwa, Muthapillai Senthilnathan, Srinivasan Suganya, Sakthirajan PanneerselvamAsian Journal of Transfusion Science 2019 13(1):63-65Hemolytic transfusion reactions (HTRs) remain one of the dreaded complications of transfusion-related morbidity and mortality. Here, we describe the diagnosis and management of acute HTR following transfusion of ABO-incompatible packed red blood cell under general anesthesia which manifested solely as acute intraoperative hematuria. A 65-year-old, diabetic male was scheduled for emergency re-explorative laparotomy in view of suspected anastomotic leak following subtotal gastrectomy. O...
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Priya Rudingwa Muthapillai Senthilnathan Srinivasan Suganya Sakthirajan Panneerselvam Source Type: research

A case of severe donor reaction leading to grievous injury
Vinu Rajendran, Revathy Nair, George Paul Thaliath, Debasish GuptaAsian Journal of Transfusion Science 2019 13(1):60-62Adverse events of variable severity may occur occasionally following whole blood donation. We are reporting a case of severe donor reaction leading to grievous injury. A first-time male voluntary blood donor donated blood in our blood donation camp. The donation was uneventful, and he left the premise after 20 min of postdonation observation and advice. Several minutes later, he fell on the road and injured himself complicated with severe delayed vaso-vagal reaction. The donor had lacerated wound over the ...
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Vinu Rajendran Revathy Nair George Paul Thaliath Debasish Gupta Source Type: research

Incompatible crossmatch: First sign of a hemolytic transfusion reaction due to out-of-group platelet transfusion
Debapriya Basu, Sabita Basu, Joydeep Roy, Mahua Reddy, Mammen Chandy, Jaydeep BhaumikAsian Journal of Transfusion Science 2019 13(1):57-59Platelet (PLT) transfusion is undertaken in a variety of clinical settings with thrombocytopenia, with or without bleeding. Since PLTs are most often stored in donor plasma, group-specific PLT transfusions are preferred to out-of-group transfusions. PLTs adsorb ABO antigens over their surface from the plasma. In major ABO-incompatible PLT transfusions, anti-A/B from the patient plasma react with the ABO antigens on transfused PLTs and can potentially cause adverse reactions or PLT refrac...
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Debapriya Basu Sabita Basu Joydeep Roy Mahua Reddy Mammen Chandy Jaydeep Bhaumik Source Type: research

A case of rare anti-Hro alloantibody in a tertiary care center in India
Mohit Chowdhry, Soma Agrawal, Uday Kumar ThakurAsian Journal of Transfusion Science 2019 13(1):54-56Anti-Hro is an alloantibody produced in individuals with -D- phenotype after a sensitizing event. Owing to the rarity of this antigen negative unit, registration in rare donor registries helps in procuring blood components at the earliest. We had a patient of -D- with anti-Hro antibody who required 7 units of red cells which was unavailable at our center. The patients near relatives were typed in search of a similar phenotype blood. Search was made for the rare units and Japanese Red Cross Society, American Red Cross Society...
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Mohit Chowdhry Soma Agrawal Uday Kumar Thakur Source Type: research

Effect of autologous PRP on wound healing in dental regenerative surgeries and its correlation with PDGF levels
Conclusions: PRP led to enhanced bone regeneration and soft-tissue healing with former being directly related to higher concentration of PDGF-BB. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Rahul Verma Gita Negi Abhishek Kandwal Harish Chandra Dushyant Singh Gaur Meena Harsh Source Type: research

Flow cytometric enumeration of CD34 & #43; hematopoietic stem cells: A comparison between single- versus dual-platform methodology using the International Society of Hematotherapy and Graft Engineering protocol
Conclusion: In our study, both single versus dual platform had similar results in CD34+ cell counts. The single platform provides rapid results with ease of procedure. Errors with dual platforms are relatively common with respect to denominator. We recommend to use mean of total leukocyte count from two different hematology analyzer to minimize variation in dual platform. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Mohandoss Murugesan Chandran K Nair Sangeetha K Nayanar Kalyana Chakravarthy Pentapati Source Type: research

A guide to organize voluntary stem cell donors recruitment drive for hematopoietic progenitor stem cell transplant
Conclusions: Here, we have demonstrated guidelines along with steps to organize voluntary stem cell donors recruitment drive that is needed to increase number of donors, thus increasing significantly the chances of saving many vital lives. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Vikash Chandra Mishra Aseem K Tiwari Pranav Dorwal Vimarsh Raina Girish Sharma Source Type: research

Antibody screening and identification in donors and general patients at a tertiary care teaching hospital in Western India
Conclusion: Antibody screening and identification of specific alloantibody help in identifying most appropriate blood unit that lacks the corresponding antigen and prevent alloimmunization. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Kamini Parshuram Gupta Maitrey D Gajjar Tarak Ramesh Patel Nidhi Manish Bhatnagar Nihar Chaudhari Mamta Chintan Shah Source Type: research

High thermal amplitude auto-anti- & #8220;N & #8221; complicating pretransfusion compatibility tests on a patient with malaria and bladder cancer
Conclusion: Auto-anti-“N” as a cause of severe anemia could not be attributed to, for concurrent malarial infection. However, its presence may have some association with the underlying malignant condition. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Sanmukh R Joshi Ankita Sheladiya Vijaykumar N Agrawal Source Type: research

A study on factors influencing the hemostatic potential of fresh frozen plasma
Conclusion: Rapid freezing is recommended for optimum preservation of coagulation factors. Thawing may be done at 45°C in cases of emergency, without compromising hemostatic potential. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Lalit Dhantole Anju Dubey Atul Sonker Source Type: research

Impact of stored red cells on clinical outcome in critically ill
Conclusion: Critically ill patients may be prioritized for receiving fresher units of packed red cells preferably less than 21 days old. Transfusion is an independent risk factor for morbidity. Hence the risk to benefit ratio should be carefully assessed for every red cell transfusion in critically ill patients. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Aaditya Shivhare Shamee Shastry Mohandoss Murugesan Karishma Ashwin Doshi B Poornima Baliga Source Type: research

Effect of plateletpheresis on postdonation serum thrombopoietin levels and its correlation with platelet counts in healthy voluntary donors
Conclusion: Serum TPO levels increase significantly post plateletpheresis donation corresponding to decrease in platelet counts showing that TPO plays a vital role in compensatory mechanism after platelet loss. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Rekha Hans Ratti Ram Sharma Neelam Marwaha Source Type: research

Reducing delivery times of emergency blood products through pneumatic tube systems
Conclusions: Delivery of blood products by our modified PTS is safe and significantly reduces delivery time. This time savings could be clinically significant in resuscitation. Usage of the PTS could also cut down on workforce utilization of porters, freeing them up for other tasks in the hospital. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Jian Hao Jaryl Kok Choong Weng Leslie Lam Mee Yin Joanne Lee Source Type: research

Greenish discoloration of plasma: Is it really a matter of concern ?
Anila Mani, AP Poornima, Debasish GuptaAsian Journal of Transfusion Science 2019 13(1):1-2 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - June 13, 2019 Category: Hematology Authors: Anila Mani AP Poornima Debasish Gupta Source Type: research

Need for plateletpheresis procedure with voluntary regular apheresis donors: An experience
Ripal J Shah, Vishvas AminAsian Journal of Transfusion Science 2018 12(2):183-184 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Ripal J Shah Vishvas Amin Source Type: research

Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat
Jitendra N Patel, Ajaykumar B Donta, Arpit C Patel, Amrish N Pandya, Swati S KulkarniAsian Journal of Transfusion Science 2018 12(2):180-182The blood specimen of a 30-year-old male donor showing a discrepancy in cell and serum grouping was targeted for detailed study at the blood bank at tertiary care hospital in South Gujarat. Forward grouping showed group as “O” RhD positive and reverse grouping as group “A.” Further testing confirmed that the individual's blood group was para-Bombay A (para-AH). Family members were screened, and younger brother was also identified as para-Bombay phenotype. Th...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Jitendra N Patel Ajaykumar B Donta Arpit C Patel Amrish N Pandya Swati S Kulkarni Source Type: research

Severe ABO hemolytic disease of fetus and newborn requiring blood exchange transfusion
We report three cases of severe ABO-HDFN where blood exchange transfusions (ETs) were required in neonates with hyperbilirubinemia. Blood grouping (ABO/RhD) was performed using conventional tube technique. The antibody screen was done using commercial three-cell panel (Bio-Rad ID-Diacell-I-II-III, Switzerland) by gel technique. Direct antiglobulin test (DAT) on neonatal sample and compatibility testing were also done by gel technique. Elution on DAT-positive sample was performed using “heat elution” method. All the three neonates were A RhD positive and were born to O RhD-positive mothers who were negative for ...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Ashish Jain Sheetal Malhotra Neelam Marwaha Praveen Kumar Ratti Ram Sharma Source Type: research

Therapeutic plasma exchange as a life-saving therapy in a suspected case of autoimmune encephalitis: A case report from a tertiary health-care center
Prashant Kumar Pandey, Nitin Agarwal, Manish GuptaAsian Journal of Transfusion Science 2018 12(2):173-175In half of the suspected autoimmune encephalitis (AIE) patients, no antibodies are identified despite extensive investigation. Therapeutic plasma exchange (TPE) is a potential first-line therapy for various subtypes of AIE. Here, we present a case of autoantibody-negative-suspected AIE, managed successfully with TPE after patient showed no response to steroids. A total of 5 sessions of TPE was done. One standard TPE procedure session was 1.2–1.5 plasma volume exchanges using 5% albumin as a replacement fluid. ...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Prashant Kumar Pandey Nitin Agarwal Manish Gupta Source Type: research

Real eyes realizes real lies: A case report and review of nuisance antibodies in immunohematology
We report one such nuisance antibody detected in an antenatal female that showed pan reaction with antibody screening and identification panel red cells including auto control but was compatible with group-specific donor units. Direct antiglobulin test was positive with no hematological evidence of bleeding. Repeat antibody screening test performed after washing the panel red cells and use of panel cells from different manufacturer showed negative reaction raising the suspicion of antibody specificity against chemical constituents in suspension medium of panel cells. Interpretation of nonspecific antibodies as to what they...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Dhivya Kandasamy Shamee Shastry Deepika Chenna Ganesh Mohan Source Type: research

Comparative evaluation of enzyme-linked immunosorbent assay with rapid plasma reagin for screening of syphilis in blood donors
Suchet Sachdev, Arun Kumar Sharma, Sunil Sethi, Sachin Garg, Divjot Singh Lamba, Ratti Ram Sharma, Neelam MarwahaAsian Journal of Transfusion Science 2018 12(2):165-168World Health Organization (WHO) recommends screening of syphilis in low prevalence populations of blood donors by treponemal tests like enzyme-linked immunosorbent assay (ELISA), whereas in India screening is done by rapid plasma reagin (RPR). The present pilot study evaluated the performance of ELISA compared to RPR, keeping Treponema pallidum hemagglutination assay as a reference test. ELISA was equally sensitive (100%), more specific (56.3% vs. 0&...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Suchet Sachdev Arun Kumar Sharma Sunil Sethi Sachin Garg Divjot Singh Lamba Ratti Ram Sharma Neelam Marwaha Source Type: research

A positive complement dependent cytotoxicity immunoglobulin G crossmatch due to auto-antibodies with a negative luminex bead assays in a renal transplant recipient: A Diagnostic dilemma
We describe a case where the patient awaiting renal transplantation from living related donor was evaluated by pretransplant histocompatibility testing for the detection of anti-HLA antibodies. The histocompatibility testing revealed positive CDC anti-human globulin and flow crossmatch along with negative Luminex based assays (HLA antibody screen, luminex crossmatch, and luminex single bead assay). Detailed histocompatibility workup revealed immunoglobulin G autoantibodies which were complement activating and lympocytoxic in nature. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Mohit Chowdhry Raj Nath Makroo Brinda Kakkar Yogita Thakur Manoj Kumar Mandhata Singh Source Type: research

Manual red cell exchange transfusion to avert sickle cell related complications
Ruhi A Mehra, Seema A Gupta, DB BorkarAsian Journal of Transfusion Science 2018 12(2):157-159Sickle cell-beta thalassemia is a double heterozygous state. Red cell exchange (RCE) transfusion reduces the concentration of sickle cells without increasing the hematocrit or whole-blood viscosity. It can be performed manually or by erythrocytapheresis. RCE transfusion is an effective tool for both acute and chronic complications of sickle cell disease. In patients unaffording erythrocytapheresis, even manual RCE can give favorable results. A 37-year-old male, a known case of sickle cell-beta+ thalassemia (βsβ+),...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Ruhi A Mehra Seema A Gupta DB Borkar Source Type: research

Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
Swati Pabbi Mehta, Aseem Kumar Tiwari, Rajesh Puri, Dinesh Arora, Geet Aggarwal, Ankita RatanAsian Journal of Transfusion Science 2018 12(2):154-156Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of s...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Swati Pabbi Mehta Aseem Kumar Tiwari Rajesh Puri Dinesh Arora Geet Aggarwal Ankita Ratan Source Type: research

Evaluation of bacterial inactivation in random donor platelets and single-donor apheresis platelets by the INTERCEPT blood system
Conclusion: The INTERCEPT system has been shown to be very effective in our study for bacterial inactivation. Implementation of INTERCEPT may be used as a mitigation against any potential bacterial contamination in platelet components. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Raj Nath Makroo Raman Sardana Leena Mediratta Hena Butta Uday Kumar Thakur Soma Agrawal Mohit Chowdhry Satendra Kumar Sourit Chokroborty Source Type: research

Audit and education: Role in safe transfusion practice
Gopal Kumar Patidar, Daljit KaurAsian Journal of Transfusion Science 2018 12(2):141-145Background: Auditing and education are the tools for improvement in the transfusion practices. Clinicians are not providing patient's demographic data and medical history to the blood bank that required transfusion. This missing information in blood request forms can lead to transfusion reactions to the patient. So we planned to analyse the blood request forms received at our blood bank and the impact of educational program for the clinicians. Methods: A total of 6894 blood request forms were received from the month of July 2014 to ...
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Gopal Kumar Patidar Daljit Kaur Source Type: research

Adding to platelet safety and life: Platelet additive solutions
Conclusion: The ABO antibody titers were significantly reduced after addition of PAS. This facilitates the ABO incompatible SDP transfusion and helps in inventory management. The risk of allergic transfusion reaction decreases after reducing the amount of plasma from SDP units. Using PAS-SDP certainly improve the inventory management for platelets with no compromise on clinical and laboratory efficacy. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Ankit Mathur Narasimha Swamy Samrat Thapa Santanu Chakraborthy Latha Jagannathan Source Type: research

Therapeutic plasma exchange for pediatric nonrenal disease indications and outcomes: A single-center experience
Conclusion: Plasma exchange was found to be beneficial as complementary therapy in a critical care setting, especially for nonrenal indications. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Saravanan Margabandhu Suchitra Ranjit Indira Jayakumar Chitra Sundaramoorthy Mahesh Janarthanan Jayakumar Reddy Meena Thiagarajan Shyamala Jayamoorthy Latha Vishwanathan Source Type: research

Intra- and inter-model reliability of Hemocue Hb 201 & #43; and HemoCue Hb 301 devices
Conclusion: The inter-instrument reliability and agreement are satisfactory in a blood bank setting. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Ashish Jain Nilotpal Chowdhury Sanchit Jain Source Type: research

Outcome of 51 autologous peripheral blood stem cell transplants after uncontrolled-rate freezing ( & #8220;dump freezing & #8221;) using & #8722;80 & #176;C mechanical freezer
Conclusion: Our analysis shows that PBSC can be successfully cryopreserved with mechanical uncontrolled rate freezing. This is a cheap and simple method to freeze the stem cells for a short period in resource-constrained setting. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Rasika Dhawan Setia Satyam Arora Anil Handoo Dharma Choudhary Sanjeev Kumar Sharma Vipin Khandelwal Meenu Kapoor Shalu Bajaj Tina Dadu Gaurav Dhamija Virendra Bachchas Source Type: research

Experience of hepatitis C virus seroprevalence and its genomic diversity among transfusion-dependent thalassemia patients in a transfusion center
Conclusions: This study clearly indicates that the incidence of transfusion-transmitted hepatitis C is high in thalassemia patients, but actual scenario of HCV viremia can only be found by HCV RNA qualitative and quantitative detection method and not by ELISA, is a major concern for this high-risk group of population. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Kallol Kumar Bhattacharyya Aritra Biswas Debanjali Gupta Provash C Sadhukhan Source Type: research

Regenerative efficacy of therapeutic quality platelet-rich plasma injections versus phonophoresis with kinesiotaping for the treatment of chronic plantar fasciitis: A prospective randomized pilot study
Conclusion: Our study concluded that therapeutic quality autologous PRP injection (1x106 platelets/μl) has regenerative effect with long and better efficacy in pain management of chronic recalcitrant plantar fasciitis than Phonophoresis and Kinesiotaping. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Nitesh Gonnade Archana Bajpayee Abhay Elhence Vaibhav Lokhande Neeraj Mehta Manish Mishra Arunpreet Kaur Source Type: research

Immunohematological and clinical characterizations of mixed autoimmune hemolytic anemia
Conclusion: Patients with MAIHA often present with severe hemolysis necessitating blood transfusions. While red cells are coated with multiple autoantibodies, both warm reactive IgG and cold reactive IgM autoantibodies are present in the serum. These serological complexities not only render a crossmatch incompatibility but often lead to blood group discrepancy. “Best match” blood transfusion is always lifesaving. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Sudipta Sekhar Das Ritam Chakrabarty RU Zaman Source Type: research

Use of infusion pump for intrauterine transfusion: An effective hands-free transfusion circuit
Shamee Shastry, Karishma Ashwin Doshi, Vijayram Reddy Kankula, Pruthvi Raj GuduriAsian Journal of Transfusion Science 2018 12(2):97-98 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Shamee Shastry Karishma Ashwin Doshi Vijayram Reddy Kankula Pruthvi Raj Guduri Source Type: research

AJTS and it & #39;s legacy of knowledge
Jayashree SharmaAsian Journal of Transfusion Science 2018 12(2):95-96 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - December 19, 2018 Category: Hematology Authors: Jayashree Sharma Source Type: research

A curious case of thick white slick in a blood bag
Anju Dubey, Atul SonkerAsian Journal of Transfusion Science 2018 12(1):93-94 (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Anju Dubey Atul Sonker Source Type: research

Detection of antibodies to co-trimoxazole (preservative drug) interfering with routine red cell antibody screening
We present a rare case of detection of anti-co-trimoxazole antibody during routine antibody screening in a female patient undergoing neurosurgery. These antibodies mimicked as antibody against high-frequency red cell antigens reacting in both saline phase as well as antiglobulin phase. Anti-co-trimoxazole antibody was confirmed by repeating antibody screen using reagent red cells of different manufacturers with and without co-trimoxazole drug as preservative as well as using washed red cell panels. There were no associated clinical or laboratory evidence of hemolysis. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Deepti Sachan S Aswin Kumar Source Type: research

Hemophagocytic lymphohistiocytosis in an infant with multiple triggers!!
We report a 9-month old infant who developed HLH in association with Stevens–Johnson syndrome following massive blood transfusion. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Sataroopa Mishra Amitabh Singh Lavleen Singh Anirban Mandal Rahul Jain Source Type: research

Anti Kpa alloantibody: Development of a rare alloantibody in a non-Hodgkin & #39;s lymphoma patient of Indian origin
We report an interesting case of Anti-Kpa in a 59-year-old female patient of Non-Hodgkin's Lymphoma, post radiotherapy, who first developed warm autoantibody and later developed anti-Kpa alloantibody on multiple transfusions. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Sadhana Mangwana Vivek Gangwar Source Type: research

Jehovah & #39;s Witness and consent for blood transfusion in a child: The Indian scenario
We present the case scenario of a child belonging to Jehovah's Witness denomination diagnosed with Burkitt lymphoma. His parents were in a dilemma whether to opt for blood transfusion or not. In the absence of laws and guidelines in this context, and considering the complications that he developed during the treatment period, it was very challenging for us to manage the situation both medically and medico-legally. This situation highlights the need for framing consensus guidelines/laws regarding elective blood transfusion in a minor to make health-care delivery, smooth, transparent and flawless. (Source: Asian Journal ...
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: KG Gopakumar T Priyakumari Manjusha Nair P Kusumakumary Source Type: research

A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
Nirav Ramesh Dava, Alok Upadhyaya, Neha Agarwal, Amarjeet Mehta, Vijaypal Choudhary, Gourav GoyalAsian Journal of Transfusion Science 2018 12(1):75-77 We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3rd order male child of G3P3A0mother was admitted at 8th h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D antigen was positive in baby. Hematological parameters showed all the signs of ongoing hemolysis, and the bilirubin level was in the zone of exchange transfusion. Exchange transfusion was done....
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Nirav Ramesh Dava Alok Upadhyaya Neha Agarwal Amarjeet Mehta Vijaypal Choudhary Gourav Goyal Source Type: research

Relationship between T2 & #42; magnetic resonance imaging-derived liver and heart iron content and serum ferritin levels in transfusion-dependent thalassemic children
Conclusions: Serum ferritin cannot reliably predict the liver and heart iron content in Indian children with β thalassemia. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Kiran Suthar Vishnu Kumar Goyal Pramod Sharma Bindu Deopa Pradeep Singh Rathore Rama Krishan Bishnoi Source Type: research

Heterogeneity of O blood group in India: Peeping through the window of molecular biology
Conclusion: In the future, molecular genotyping of the ABO blood group system among different ethnic and tribal Indian groups would help in generating data to fill up the gaps in the molecular ABO map of the world. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Harita Gogri Sabita Ray Snehal Agrawal S Aruna Kanjaksha Ghosh Ajit Gorakshakar Source Type: research

Effect of plasma component transfusion on conventional coagulation screening tests
Conclusion: FFP transfusions as a prophylactic measure especially in patients with mildly deranged conventional coagulation screening tests without any empirical evidence of clinical bleeding needs further scrutiny. Reduction in INR following FFP transfusions was better in cohort having higher pre-transfusion INR value (> 3.0). (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Manish Raturi Shamee Shastry Mohandoss Murugesan Poornima B Baliga Kalyana Chakravarthy Source Type: research

An approach to incompatible cross-matched red cells: Our experience in a major regional blood transfusion center at Kolkata, Eastern India
Conclusion: This study showed antibody against the Rh system as the most common cause of incompatibility. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Prasun Bhattacharya Eeshita Samanta Nowroz Afroza Archana Naik Rathindranath Biswas Source Type: research

Identification of iron status of blood donors by using low hemoglobin density and microcytic anemia factor
Conclusion: LHD% and Maf in the screening of blood donors raise the possibility of early detection of iron deficiency, without the need of extra cost and blood sampling. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Ashutosh Singh Rajendra Chaudhary Hem C Pandey Atul Sonker Source Type: research

Advantages of type and screen policy: Perspective from a developing country!
Conclusion: Use of 'TS with IS crossmatch' policy provides multiple advantages to all the stakeholders; blood banker, clinician, patient, and the hospital management. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Geet Aggarwal Aseem K Tiwari Dinesh Arora Ravi C Dara Devi P Acharya Gunjan Bhardwaj Jyoti Sharma Source Type: research