Archives of Disease in Childhood - Fetal and Neonatal Edition This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Neonates with mild hypoxic-ischaemic encephalopathy receiving supportive care versus therapeutic hypothermia in California
Conclusions Variation in management of mild HIE persists, but therapeutic drift has become more prevalent over time. Further studies are needed to assess long-term outcomes alongside resource utilisation to inform evidence-based practice. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Yieh, L., Lee, H., Lu, T., Song, A., Gong, C. L., Wu, T.-W., Friedlich, P., Lakshmanan, A., Dukhovny, D., Hay, J. Tags: Original research Source Type: research

Mortality and significant neurosensory impairment in preterm infants: an international comparison
Conclusions Composite outcome of mortality or sNSI for extremely preterm infants differed across high-income countries with similar baseline characteristics and access to healthcare. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Chevallier, M., Debillon, T., Darlow, B. A., Synnes, A. R., Pierrat, V., Hurrion, E., Yang, J., Ego, A., Ancel, P. Y., Lui, K., Shah, P. S., Luu, T. M., Australian and New Zealand Neonatal Network (ANZNN), Canadian Neonatal Network (CNN), Canadian Neonata Tags: Original research Source Type: research

Comparison of intraosseous and intravenous epinephrine administration during resuscitation of asphyxiated newborn lambs
Conclusions Intraosseous epinephrine administration results in similar outcomes to intravenous epinephrine during resuscitation of asphyxiated newborn lambs. These findings support the inclusion of intraosseous access as a route for epinephrine administration in current guidelines. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Roberts, C. T., Klink, S., Schmölzer, G. M., Blank, D. A., Badurdeen, S., Crossley, K. J., Rodgers, K., Zahra, V., Moxham, A., Roehr, C. C., Kluckow, M., Gill, A. W., Hooper, S. B., Polglase, G. R. Tags: Original research Source Type: research

Implementation of an adapted Sepsis Risk Calculator algorithm to reduce antibiotic usage in the management of early onset neonatal sepsis: a multicentre initiative in Wales, UK
Conclusions This multicentre study provides evidence that a judicious adaptation of the SRC incorporating enhanced surveillance can be safely introduced in the National Health Service and is effective in reducing antibiotic use for EONS without increasing morbidity and mortality. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Goel, N., Cannell, S., Davies, G., Natti, M. S., Kirupaalar, V., Abelian, A., Saeed, S., Smith, R., Manikonda, R., Pitchaikani, P. K., Davies, D., Morris, R. M., Edwards, L., Govindaraju, R., Creese, K., Jones, J., Choudhary, J., Rowley, S., Sethuraman, C Tags: Original research Source Type: research

Identification of treatment-warranted retinopathy of prematurity by neonatal nurse specialist
Conclusion A trained and experienced ROP neonatal nurse specialist can correctly identify infants with treatment-warranted ROP using WFDRI. Further work is required to examine the generalisability of this finding and its impact on ROP screening services. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Ravelo, J., Adams, G., Husain, S. Tags: Original research Source Type: research

Monitoring of carbon dioxide in ventilated neonates: a prospective observational study
Conclusion DetCO2 had better reliability, accuracy and precision with paCO2 than tcCO2 in ventilated neonates without severe lung diseas. Trial registration number NCT03758313. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Werther, T., Aichhorn, L., Stellberg, S., Cardona, F. S., Klebermass-Schrehof, K., Berger, A., Schmölzer, G. M., Wagner, M. Tags: Original research Source Type: research

Comparison of three intraosseous access devices for resuscitation of term neonates: a randomised simulation study
Conclusions Although easier to use, the EZ-IO drill demonstrated lower success rates than the IO needles in establishing IO access on a neonatal bone model. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Keller, A., Boukai, A., Feldman, O., Diamand, R., Shavit, I. Tags: Original research Source Type: research

Individualised decision making: interpretation of risk for extremely preterm infants--a survey of UK neonatal professionals
Conclusion UK neonatal professionals deferred to parental wishes in the cases presented, indicating an emphasis on shared decision making. However, they did not necessarily use the risk stratification approach for management decisions. Variation in estimates of outcome raises questions about the accuracy of informed decision making and suggests support is needed for UK clinicians to incorporate risk factors into individualised counselling. There may be value in validating existing online risk calculators for UK infants or in developing a UK specific risk model. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Wood, K., Di Stefano, L. M., Mactier, H., Bates, S. E., Wilkinson, D. Tags: Open access Original research Source Type: research

Outcomes of very preterm infants with neonatal hyperglycaemia: a systematic review and meta-analysis
Conclusion Hyperglycaemia in very preterm infants is associated with higher odds of mortality, any-grade IVH and any-stage ROP. A limitation was lack of availability of adjusted ORs from many of the included studies. PROSPERO registration number CRD42020193016. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Rath, C. P., Shivamallappa, M., Muthusamy, S., Rao, S. C., Patole, S. Tags: Original research Source Type: research

Assessment of optimal chest compression depth during neonatal cardiopulmonary resuscitation: a randomised controlled animal trial
Conclusions Time to return of spontaneous circulation and survival were similar between 25%, 33% and 40% anterior-posterior depths, while 12.5% anterior-posterior depth did not result in return of spontaneous circulation or survival. Haemodynamic and respiratory parameters improved with increasing anterior-posterior depth, suggesting improved organ perfusion and oxygen delivery with 33%–40% anterior-posterior depth. Trial registration number PTCE0000193. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Bruckner, M., Kim, S. Y., Shim, G. H., Neset, M., Garcia-Hidalgo, C., Lee, T.-F., O'Reilly, M., Cheung, P.-Y., Schmölzer, G. M. Tags: Original research Source Type: research

Ecthyma gangrenosum in a premature infant: rare but critical to recognise
A premature male infant born at 26+1 weeks of gestation, with a birth weight of 615 g (<p1), was admitted to the neonatal intensive care unit. In the absence of risk factors, no antibiotics were started initially. Directly after birth, neutropenia (0.9x109/L) was noted, most likely explained by dysmaturity. On day 3, he showed symptoms of infection, including hypotension and a necrotic ulcer in the right armpit (figure 1). Laboratory testing revealed an elevated C reactive protein (CRP) and persistent neutropenia. Antibiotic treatment was started after obtaining a blood culture, which showed no growth. A swab of the ulc...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Caron, M., Oliveira dos Santos, C., Hemels, M. A. C., d'Haens, E. J. Tags: Images in neonatal medicine Source Type: research

Temporal trends in routine predischarge pulse oximetry screening: 6 years experience in a UK regional neonatal unit
Conclusions Routine POS, in addition to antenatal screening and postnatal examination, continues to contribute to the improvement of our overall CCHD detection rates. We have demonstrated an overall reduction in the admission of healthy babies and therefore workload following a positive test. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Henderson, A., Aguirre, D., Singh, A., Ewer, A. K. Tags: Editor's choice Original research Source Type: research

Antenatal corticosteroids and neurodevelopmental outcomes in late preterm births
Conclusion In children born during the LPT period, exposure to ACS prior to 340/7 weeks of gestation is associated with an increased utilisation of the healthcare system related to audiometry and visual testing and suspected neurocognitive disorders by 5 years of age. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Aviram, A., Murphy, K., McDonald, S., Asztalos, E., Zaltz, A., Redelmeier, D., Shah, B., Barrett, J., Melamed, N. Tags: Original research Source Type: research

Neuroscience meets nurture: challenges of prematurity and the critical role of family-centred and developmental care as a key part of the neuroprotection care bundle
Advances in neonatal–perinatal medicine have resulted in increased survival at lower gestations. Although the incidence of germinal matrix haemorrhage-intraventricular haemorrhage and cystic periventricular leucomalacia is reducing, a new phenotype of preterm brain injury has emerged consisting of a combination of destructive and dysmaturational effects. Consequently, severe neurological disability is reported at a lower rate than previously, but the overall morbidity associated with premature birth continues to present a large global burden and contributes significantly to increased financial costs to health systems...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Soni, R., Tscherning Wel-Wel, C., Robertson, N. J. Tags: Reviews Source Type: research

Early recognition of rusty pipe syndrome to avoid disruption of breast feeding
This report illustrates the situation where exclusive breast feeding was interrupted due to healthcare staff’s unfamiliarity with RPS. RPS describes rusty-looking breastmilk caused by the presence of blood clots due to rapid alveolar and ductal vascularisation in pregnancy and early lactation. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 20, 2022 Category: Perinatology & Neonatology Authors: Low, J. M., Amin, Z., Ng, Y. P. M. Tags: Images in neonatal medicine Source Type: research