Archives of Disease in Childhood - Fetal and Neonatal Edition This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Diagnosis of hydrocephalus by cranial transillumination
A full-term neonate was examined to have significant macrocephaly (>>97th percentile), widened cranial sutures and a large bulging anterior fontanelle (AF). A light-emitting diode source applied on the AF revealed asymmetrical cranial transillumination, predominantly on the right (figure 1A). He was alert with spontaneous movements of all limbs but had generalised upper motor neuron (UMN) signs of hypertonia and hyper-reflexia. These signs indicated raised intracranial pressure from a possible right hemispheric cystic lesion. MRI showed a large right open-lip schizencephaly with encysted cerebrospinal fluid (CSF) tha...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Lian, B. X., Ng, N. B. H., Wang, F., Nga, V. D. W., Tan, A. P., Lin, J. Tags: Images in neonatal medicine Source Type: research

Predictors of anastomotic strictures following {oelig}sophageal atresia repair
Conclusions Patient-related anatomical factors leading to anastomosis under tension and delayed anastomosis increase the risk of anastomotic stricture. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Aumar, M., Sfeir, R., Pierache, A., Turck, D., Gottrand, F., on behalf of CRACMO Tags: Original research Source Type: research

Preliminary study of automated oxygen titration at birth for preterm infants
Conclusion Automated oxygen titration using a purpose-built algorithm is feasible for delivery room management of preterm infants, and warrants further evaluation. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Ali, S. K., Jayakar, R. V., Marshall, A. P., Gale, T. J., Dargaville, P. A. Tags: Original research Source Type: research

Associations of body composition with regional brain volumes and white matter microstructure in very preterm infants
Conclusions Lean mass—but not fat—at term was associated with larger brain volume and white matter microstructure differences that suggest improved maturation. Lean mass accrual may index brain growth and development. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Bell, K. A., Matthews, L. G., Cherkerzian, S., Prohl, A. K., Warfield, S. K., Inder, T. E., Onishi, S., Belfort, M. B. Tags: Original research Source Type: research

Severe neonatal hyperbilirubinaemia: lessons learnt from a national perinatal audit
Conclusions SNH remains a serious threat to neonatal health in the Netherlands. ABO antagonism frequently underlies SNH. Lack of compliance to the national guideline including insufficient a priori hyperbilirubinaemia risk assessment, and communication among healthcare providers are important improvable factors. Implementation of universal bilirubin screening and better documentation of the risk of hyperbilirubinaemia may enhance early recognition of potentially dangerous neonatal jaundice. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: van der Geest, B. A. M., Rosman, A. N., Bergman, K. A., Smit, B. J., Dijk, P. H., Been, J. V., Hulzebos, C. V. Tags: Original research Source Type: research

MRI-based brain volumes of preterm infants at term: a systematic review and meta-analysis
Conclusion This meta-analysis reports pooled data on several brain and cerebellar volumes which can serve as reference for future studies assessing MR-based volumetric parameters as a surrogate outcome for neurodevelopment and for the interpretation of individual or cohort MRI-based volumetric findings. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Romberg, J., Wilke, M., Allgaier, C., Nägele, T., Engel, C., Poets, C. F., Franz, A. Tags: Open access Original research Source Type: research

Global incidence proportion of intraventricular haemorrhage of prematurity: a meta-analysis of studies published 2010-2020
Conclusions We report the first pooled estimates of IVH of prematurity by GA subgroup. There was high heterogeneity across studies suggesting a need for standardised incidence reporting guidelines. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Lai, G. Y., Shlobin, N., Garcia, R. M., Wescott, A., Kulkarni, A. V., Drake, J., Dizon, M. L., Lam, S. K. Tags: Original research Source Type: research

Effects of tactile stimulation on spontaneous breathing during face mask ventilation
Conclusions Tactile stimulation during PPV was associated with an increase in the number of spontaneous breaths compared with immediately before stimulation without a change in mask leak and obstruction. These data inform the discussion on continuing stimulation during PPV in term infants. Trial registration number Australian and New Zealand Clinical Trial Registry (ACTRN12616000768493). (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Gaertner, V. D., Rüegger, C. M., Bassler, D., O'Currain, E., Kamlin, C. O. F., Hooper, S. B., Davis, P. G., Springer, L. Tags: Original research Source Type: research

Effect of prophylactic dextrose gel on the neonatal gut microbiome
Conclusions Clinicians and consumers can be reassured that dextrose gel used for prophylaxis or treatment of neonatal hypoglycaemia does not alter the neonatal gut microbiome. Trial registration number 12614001263684. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: St Clair, S. L., Harding, J. E., OSullivan, J. M., Gamble, G. D., Alsweiler, J. M., Vatanen, T., for the hPOD Study Group Tags: Original research Source Type: research

Parental perspective on important health outcomes of extremely preterm infants
Conclusions Parents evaluate the health of their preterm children as being very good, with positive perspectives. Parental concerns outside the developmental sphere should also be addressed both in clinical follow-up and research. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Jaworski, M., Janvier, A., Bourque, C. J., Mai-Vo, T.-A., Pearce, R., Synnes, A. R., Luu, T. M. Tags: Open access Original research Source Type: research

Single versus continuous sustained inflations during chest compressions and physiological-based cord clamping in asystolic lambs
Conclusion We found no significant benefit of SIcont over SIsing during CPR on the time to ROSC or on post-ROSC haemodynamics, but did demonstrate the feasibility of continuous SIs during advanced CPR on an intact umbilical cord. Longer-term studies are recommended before this technique is used routinely in clinical practice. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Schmölzer, G. M., Roberts, C. T., Blank, D. A., Badurdeen, S., Miller, S. L., Crossley, K. J., Stojanovska, V., Galinsky, R., Kluckow, M., Gill, A. W., Hooper, S. B., Polglase, G. R. Tags: Open access Original research Source Type: research

Impact of maternal obesity on neonatal heart rate and cardiac size
Conclusion Maternal obesity was associated with increased heart rate, decreased heart rate variability and decreased left ventricular volumes in newborns. If persistent, these changes may provide a causal mechanism for the increased cardiovascular risk in adult offspring of mothers with obesity. In turn, modifying antenatal and perinatal maternal health may have the potential to optimise long-term cardiovascular health in offspring. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Groves, A. M., Price, A. N., Russell-Webster, T., Jhaveri, S., Yang, Y., Battersby, E. E., Shahid, S., Costa Vieira, M., Hughes, E., Miller, F., Briley, A. L., Singh, C., Seed, P. T., Chowienczyk, P. J., Stern, K. W. D., Cohen, J., Pasupathy, D., Edwards, Tags: Original research Source Type: research

Dual-site blood culture yield and time to positivity in neonatal late-onset sepsis
Conclusion Concurrently drawn peripheral and catheter BCx had similar yield. While a majority of episodes demonstrated dual-site BCx growth, a small but important minority of episodes grew virulent pathogens from either culture site alone. While dual-site culture practices may be useful, clinicians should balance the gain in sensitivity of bacteraemia detection against additive contamination risk. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: Coggins, S. A., Harris, M. C., Srinivasan, L. Tags: Original research Source Type: research

Two-year neurodevelopmental outcome in children born extremely preterm: the EPI-DAF study
Conclusions Lowering the threshold has not been accompanied by a large increase in moderate-to-severely impaired infants. Among live-born and NICU-admitted infants, an increase in NDI-free survival was observed from 24 weeks’ to 26 weeks’ gestation. This description of a national cohort with high follow-up rates gives an accurate description of the range of outcomes that may occur after extremely preterm birth. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: van Beek, P. E., Rijken, M., Broeders, L., ter Horst, H. J., Koopman-Esseboom, C., de Kort, E., Laarman, C., Mulder-de Tollenaer, S. M., Steiner, K., Swarte, R. M., van Westering-Kroon, E., Oei, S. G., Leemhuis, A. G., Andriessen, P., on behalf of the EPI Tags: Open access, Editor's choice Original research Source Type: research

Neonatal and fetal therapy of congenital diaphragmatic hernia-related pulmonary hypertension
Congenital diaphragmatic hernia (CDH) is a complex malformation characterised by a triad of pulmonary hypoplasia, pulmonary hypertension (PH) and cardiac ventricular dysfunction. Much of the mortality and morbidity in CDH is largely accounted for by PH, especially when persistent beyond the neonatal period and refractory to available treatment. Gentle ventilation, haemodynamic optimisation and pulmonary vasodilation constitute the foundations of neonatal treatment of CDH-related PH (CDH-PH). Moreover, early prenatal diagnosis, the ability to assess severity and the developmental nature of the condition generate the perfect...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2022 Category: Perinatology & Neonatology Authors: De Bie, F. R., Avitabile, C. M., Joyeux, L., Hedrick, H. L., Russo, F. M., Basurto, D., Deprest, J., Rintoul, N. E. Tags: Reviews Source Type: research