White paper peanut allergy —part 2: Diagnosis of peanut allergy with special emphasis on molecular component diagnostics
ConclusionThe most important diagnostic measures in determining the diagnosis of peanut allergy are clinical history and detection of sensitizations, also via component-based diagnostics. However, in case of unclear results, the gold standard —an oral food challenge—should always be used. (Source: Allergo Journal International)
Source: Allergo Journal International - December 6, 2021 Category: Allergy & Immunology Source Type: research
White paper on peanut allergy: treatment pathway
ConclusionsAfter established diagnosis the standard of care is counseling to avoid peanut contact and prescription of emergency medications (oral antihistamines, oral steroids, inhaled β2-agonists, injectable intramuscular epinephrine) as needed. Instruction on the use of these emergency medications should be provided. A preparation for oral immunotherapy (OIT) for 4 to 17 years old peanut allergic children/ adolescents has been recently approved by the regulatory authorities. O IT for peanut allergy shows high efficacy and an acceptable safety profile, improves quality of life, and health economic aspects. Thus it offer...
Source: Allergo Journal International - December 6, 2021 Category: Allergy & Immunology Source Type: research
Good manufacturing practice- and good distribution practice-compliant cold storage and refrigerated transport of allergen products: what is important?
ConclusionMonitoring of storage and transport conditions is achieved by transport in qualified means of transport (e.g. truck). Alternatively, qualified transport packaging with active or passive cooling (e.g. cold packs) and qualified “data loggers” that record the transport temperatures can be used. Regardless of the system used, it must be demonstrated—by validating the transport conditions, routes and packaging at different times of the year and over the entire duration of transport—that regulatory requirements are met and that the quality of the products is maintained during shipment. (Source: Allergo Journal International)
Source: Allergo Journal International - November 22, 2021 Category: Allergy & Immunology Source Type: research
Food intolerances —a diagnostic challenge
AbstractBackgroundFood-associated complaints in the gastrointestinal tract can be signs of an intolerance of different etiology, which is reported by almost a quarter of the population. Due to the unspecific symptoms, a whole range of different triggers and immune reactions can be considered for the differential diagnosis, which cannot always be determined unambiguously and quickly.Differentiation and diagnosis of disease entityThe time course in connection with the clinical picture already allows a rough estimation of the underlying pathomechanism and points the diagnostic way. Thus, immune-mediated clinical pictures...
Source: Allergo Journal International - November 22, 2021 Category: Allergy & Immunology Source Type: research
Tolerability, course and follow-up of specific immunotherapy using a modified ultra-rush procedure in children and adolescents with insect venom allergy
DiscussionUltra-rush AIT in childhood and adolescence is safe, tolerable and effective. HG-AIT has a lasting positive effect on the health-related quality of life of patients. However, after the end of HG-AIT, there are deficits in the follow-up and care of the patients. (Source: Allergo Journal International)
Source: Allergo Journal International - November 3, 2021 Category: Allergy & Immunology Source Type: research
How do food businesses provide information on allergens in non-prepacked foods? A cross-sectional survey in Switzerland
ConclusionSo far, not all food businesses have been complying with the new Swiss food law on allergen information of non-prepacked food. Therefore, awareness of the legal obligations around communicating allergen information as well as the verification of its implementation should be enhanced. To meet the needs of consumers and avoid reactions, some form of written allergen information should be promoted. Giving this information on request might encourage communication between customer and staff, thus providing an extra measure of verification. (Source: Allergo Journal International)
Source: Allergo Journal International - November 3, 2021 Category: Allergy & Immunology Source Type: research
White paper on peanut allergy – part 1: Epidemiology, burden of disease, health economic aspects
AbstractPeanuts are Leguminosae, commonly known as the legume or pea family, and peanut allergy is among the most common food allergies and the most common cause of fatal food reactions and anaphylaxis.The prevalence of peanut allergy increased 3.5-fold over the past two decades reaching 1.4 –2% in Europe and the United States. The reasons for this increase in prevalence are likely multifaceted. Sensitization via the skin appears to be associated with the development of peanut allergy and atopic eczema in infancy is associated with a high risk of developing peanut allergy.Until recently, the only possible management str...
Source: Allergo Journal International - September 28, 2021 Category: Allergy & Immunology Source Type: research
Messages for patients and relatives from the 2021 update of the guideline on acute therapy and management of anaphylaxis
(Source: Allergo Journal International)
Source: Allergo Journal International - September 27, 2021 Category: Allergy & Immunology Source Type: research
Correction to: Health care situation in patients with allergic respiratory diseases with special focus on specific immunotherapy
(Source: Allergo Journal International)
Source: Allergo Journal International - September 22, 2021 Category: Allergy & Immunology Source Type: research
Risk factors in bee and Vespula venom allergy: state of the art
SummaryBackgroundCorrect recognition of risk factors enables individualized management and treatment of venom allergic patients.MethodsSystematic research and review of current literature regarding the risk of (1) severe sting-induced anaphylaxis, (2) anaphylactic adverse event during venom immunotherapy (VIT), and (3) treatment failure.Results and discussion(1) Mastocytosis is the most important risk factor for severe sting-induced anaphylaxis. Hereditary α‑tryptasemia was recently identified as a genetic predictor of severe reactions. Older age is clearly associated with an increased risk; the respective impact...
Source: Allergo Journal International - September 15, 2021 Category: Allergy & Immunology Source Type: research
Abstracts of the 16th German Allergy Congress Dresden, September 30 –October 2, 2021
(Source: Allergo Journal International)
Source: Allergo Journal International - September 3, 2021 Category: Allergy & Immunology Source Type: research
Nasal cytology identifies allergic rhinitis phenotypes for managing allergen immunotherapy in clinical practice
ConclusionNasal cytology is a fruitful tool to identify non-responder to AIT and phenotype mixed rhinitis, such as AR associated with NARES. Therefore, nasal cytology is useful in AIT management, mainly in non-responders. (Source: Allergo Journal International)
Source: Allergo Journal International - September 1, 2021 Category: Allergy & Immunology Source Type: research
Type I allergic reactions to roe deer (Capreolus capreolus), red deer (Cervus elaphus), and chamois (Rupicapra rupicapra) in a single hunter
(Source: Allergo Journal International)
Source: Allergo Journal International - August 24, 2021 Category: Allergy & Immunology Source Type: research
Real world effectiveness and cost consequences of grass pollen SCIT compared with SLIT and symptomatic treatment
ConclusionAIT represents a cost-effective treatment option for patients with allergic rhinitis compared with symptomatic treatment. SCIT appeared to be dominant and cost-effective, due in particular to higher patient adherence and lower drug costs. (Source: Allergo Journal International)
Source: Allergo Journal International - August 6, 2021 Category: Allergy & Immunology Source Type: research
Anaphylatic reaction after chamomile tea consumption
(Source: Allergo Journal International)
Source: Allergo Journal International - July 21, 2021 Category: Allergy & Immunology Source Type: research
