Vitamin A and D in allergy: from experimental animal models and cellular studies to human disease
ConclusionAnimal studies predict that vitamin A and D may also be attractive players in the control of allergy in humans. Whether these experimental observations can be translated to the human situation remains open, as results from clinical trials are controversial. (Source: Allergo Journal International)
Source: Allergo Journal International - February 20, 2018 Category: Allergy & Immunology Source Type: research
Sesame allergies: clinical significance, diagnosis, and therapy
ConclusionBeside diagnostic measurements including skin tests, detection of IgE antibodies and oral provocation tests, the education of patients with sesame allergy is of particular importance. This serves, firstly, to prevent recurrence of allergen exposure and, secondly, should contain information on self-management in the case of repeated reactions. The value of oral tolerance induction and preventive measures such as early introduction as a dietary supplement remains to be clarified in the future. (Source: Allergo Journal International)
Source: Allergo Journal International - February 12, 2018 Category: Allergy & Immunology Source Type: research
A century of “intrinsic asthma”
ConclusionToday, the term asthma is looked at as an umbrella covering different phenotypes of the disease. According to a recent publication, Intrinsic Asthma is most often cited now as eosinophilic adult-onset asthma. New treatment strategies for this phenotypes have evolved in recent years. (Source: Allergo Journal International)
Source: Allergo Journal International - February 12, 2018 Category: Allergy & Immunology Source Type: research
Abstracts of the 30th Spring Symposium of the German Society of Allergy and Clinical Immunology. Mainz, March 22-23, 2018
(Source: Allergo Journal International)
Source: Allergo Journal International - January 25, 2018 Category: Allergy & Immunology Source Type: research
Subtyping of polyposis nasi: phenotypes, endotypes and comorbidities
ConclusionThe identification of different endotypes of CRSwNP may help to improve
diagnostics and develop novel individual treatment approaches in CRSwNP. (Source: Allergo Journal International)
Source: Allergo Journal International - January 22, 2018 Category: Allergy & Immunology Source Type: research
Abstracts of the 30th Spring Symposium of the German Society of Allergy and Clinical Immunology
(Source: Allergo Journal International)
Source: Allergo Journal International - January 17, 2018 Category: Allergy & Immunology Source Type: research
Current state of follow-up care for patients with Hymenoptera venom anaphylaxis in southwest Germany
ConclusionOur results demonstrate that there are missed opportunities for secondary and tertiary prevention of anaphylaxis due to insect venom allergy and that early information on required diagnostics and treatment options has a major impact on the degree of proper follow-up care in line with current guideline recommendations. (Source: Allergo Journal International)
Source: Allergo Journal International - January 16, 2018 Category: Allergy & Immunology Source Type: research
Management of severe drug reactions: a retrospective monocentric analysis
ConclusionDue to the rarity and heterogeneity of this patient population, there is scant reliable data on the systemic treatment of SJS/TEN. Therefore, whether it confers an evident benefit remains unclear. Although the allergy diagnostic testing of severe adverse drug reactions is complex, it is often able to yield important insights and should be performed. (Source: Allergo Journal International)
Source: Allergo Journal International - January 15, 2018 Category: Allergy & Immunology Source Type: research
Urticaria: an update on diagnostics, therapy, and differential diagnosis
AbstractUrticaria is a common skin disorder that can occur at any age; middle-aged women are most commonly affected. The diagnosis of urticaria is straightforward: the clinical picture includes wheals and/or angioedema accompanied by extreme itch. As a general rule, a wheal lasts for up to 1 day, whilst mast cell-med iated angioedema can remain symptomatic for up to 2 days. A distinction is made between acute and chronic forms (≥6 weeks), whereby symptoms may be present every day. Relapsing disease courses have also been described. This paper presents a current overview.Urticaria requires a detailed patient his...
Source: Allergo Journal International - January 11, 2018 Category: Allergy & Immunology Source Type: research
Allergen-specific immunotherapy with storage mites
AbstractAs a result of the German Therapy Allergen Ordinance and justified demands for large, double-blind, placebo-controlled studies on allergen-specific immunotherapy, rare therapy allergens as immunotherapeutic agents have moved out of the scientific and allergological spotlight. Allergen-specific immunoth erapy with house dust mite extracts is well established, but beside house dust mites, storage mites may cause similar allergic symptoms that also require a causal treatment. Especially in Asia storage mites are the most important inhalative allergens, but they are important allergens as well for so me patients in ...
Source: Allergo Journal International - December 14, 2017 Category: Allergy & Immunology Source Type: research
The impact of allergy on asthma in the clinical practice
(Source: Allergo Journal International)
Source: Allergo Journal International - December 11, 2017 Category: Allergy & Immunology Source Type: research
Correction to: Guideline for the diagnosis of drug hypersensitivity reactions
Correction to:Allergo J Int 2015https://doi.org/10.1007/s40629-015-0052-6Suspected drug hypersensitivity reactions require allergological investigation in order, firstly, to prevent severe reactions upon renewed exposure or, secondly, to avoid unnecessary drug restrictions. Skin tests are … (Source: Allergo Journal International)
Source: Allergo Journal International - December 6, 2017 Category: Allergy & Immunology Source Type: research
Technical specifications of the Global Allergy and Asthma European Network (GA 2 LEN) chamber: a novel mobile allergen exposure chamber
ConclusionThe GA2LEN chamber provides a novel mobile exposure chamber technology for research and clinical trials allowing a fast, affordable, and standardized multicenter approach. (Source: Allergo Journal International)
Source: Allergo Journal International - November 20, 2017 Category: Allergy & Immunology Source Type: research
New trends in anaphylaxis
AbstractThis review presents the current trends in anaphylaxis management discussed at the fourth International Network for Online-Registration of Anaphylaxis (NORA) conference held in Berlin in April 2017. Current data from the anaphylaxis registry show that Hymenoptera venom, foods, and pharmaceutical drugs are still among the most frequent triggers of anaphylaxis. Rare triggers include chicory, cardamom, asparagus, and goji berries. A meta-analysis on recent trends in insect venom anaphylaxis demonstrated for the first time that, although data on the efficacy of insect venom immunotherapy is limited, the occurrence of...
Source: Allergo Journal International - November 15, 2017 Category: Allergy & Immunology Source Type: research
Correction to: Abstracts of the 12th German Allergy Congress
Correction to:Allergo J Int 2017https://doi.org/10.1007/s40629-017-0036-9The original article has been corrected. Erroneously, in the online html article “abstract” was given as article … (Source: Allergo Journal International)
Source: Allergo Journal International - October 25, 2017 Category: Allergy & Immunology Source Type: research
