Case series of anaphylactic reactions after rabies vaccinations with gelatin sensitization
AbstractSide effects due to allergic reactions to vaccine antigen or to additives such as chicken protein or gelatin have been known for some time. Recent findings regarding reactions mediated via the carbohydrate epitope galactose-alpha-1,3-galactose (alpha-gal), a  constituent of animal gelatin, broaden the spectrum of gelatin-related allergies. This case series presents four patients who developed anaphylactic reactions following rabies vaccination using the vaccine Rabipur®. After appropriate allergy testing by skin prick testing and the determination of specific IgE to allergens in the vaccine, triggering by alpha-g...
Source: Allergo Journal International - April 17, 2019 Category: Allergy & Immunology Source Type: research

Evolution of subcutaneous allergen immunotherapy (part  1): from first developments to mechanism-driven therapy concepts
ConclusionWhen adequately administered by physicians with allergological expertise, SCIT preparations are safe, well-tolerated, and clinically effective. (Source: Allergo Journal International)
Source: Allergo Journal International - April 14, 2019 Category: Allergy & Immunology Source Type: research

Consumer protection and risk assessment: sensitising substances in consumer products
ConclusionsToday, skin sensitising substances can be legally regulated and labelled and, depending on the exposure, their content in consumer products can be reduced or eliminated. Furthermore, the risk assessment of potentially sensitising substances makes consumer products safer. Further improvements in research approaches are required in the area of health and consumer protection with regard to allergy. (Source: Allergo Journal International)
Source: Allergo Journal International - April 1, 2019 Category: Allergy & Immunology Source Type: research

Wheat-dependent exercise-induced anaphylaxis with Tri-a-14-sensitization as part of a  lipid transfer protein syndrome
(Source: Allergo Journal International)
Source: Allergo Journal International - February 14, 2019 Category: Allergy & Immunology Source Type: research

Abstracts of the 31st Spring Symposium of the German Society of Allergy and Clinical Immunology
(Source: Allergo Journal International)
Source: Allergo Journal International - January 29, 2019 Category: Allergy & Immunology Source Type: research

Guideline: Hereditary angioedema due to C1 inhibitor deficiency
(Source: Allergo Journal International)
Source: Allergo Journal International - January 17, 2019 Category: Allergy & Immunology Source Type: research

Abstracts of the 31th Spring Symposium of the German Society of Allergy and Clinical Immunology
(Source: Allergo Journal International)
Source: Allergo Journal International - January 15, 2019 Category: Allergy & Immunology Source Type: research

Prevalence of Hymenoptera venom allergy and sensitization in the population-representative German KORA cohort
ConclusionsSelf-reported Hymenoptera sting reactions and venom sensitization are frequent in the general German population. In many cases, sensitization and clinically relevant allergy are not observed in the same individual, indicating that comprehensive diagnostic approaches are a  prerequisite for the identification of patients at risk for severe reactions. (Source: Allergo Journal International)
Source: Allergo Journal International - January 9, 2019 Category: Allergy & Immunology Source Type: research

Comparison of extended intervals and dose reduction of omalizumab for asthma control
ConclusionIf patients or physicians wish to reduce the cumulative dose of omalizumab after achieving good asthma control, extension of the interval between doses appears to be a  better approach than dose reduction. (Source: Allergo Journal International)
Source: Allergo Journal International - December 14, 2018 Category: Allergy & Immunology Source Type: research

Occupational asthma due to tampico fiber bystander exposure in a  brush production company—case report and literature review
ConclusionTampico fibers are robust fibers obtained from the leaves of the MexicanAgave lechugilla. The literature describes several cases of skin reactions in the form of irritant contact dermatitis due to occupational exposure to agave leaves or contact with agave sap. In the present case, the asthma symptoms of a  female worker in a brush factory were attributed to inhalant bystander exposure to tampico fibers in the workplace. The unequivocal evidence of sensitization to tampico fibers met the medical requirements for the recognition of an occupational disease (BK 4301). (Source: Allergo Journal International)
Source: Allergo Journal International - December 3, 2018 Category: Allergy & Immunology Source Type: research

Alpha-tocopherol acetate nasal spray in the treatment of pollen-induced allergic rhinitis
ConclusionATANS can be considered an effective symptomatic treatment for patients with allergic rhinitis who wish to avoid side effects of antihistamines and corticosteroids.Trial registrationGerman “Register Klinischer Studien” (Reference number: DRKS00009338) (Source: Allergo Journal International)
Source: Allergo Journal International - November 28, 2018 Category: Allergy & Immunology Source Type: research

Safety of a  high-dose house dust mite allergoid in pediatric patients
(Source: Allergo Journal International)
Source: Allergo Journal International - November 6, 2018 Category: Allergy & Immunology Source Type: research

Allergen immunotherapy for oral allergy syndrome: what is the evidence for efficacy?
ConclusionReliable recommendations on the use of AIT with pollen allergens in pollen-related food allergy are not possible as yet. AIT with birch pollen allergens appears to have a  positive effect on concomitant food allergy in some patients with birch pollen allergy. (Source: Allergo Journal International)
Source: Allergo Journal International - October 25, 2018 Category: Allergy & Immunology Source Type: research

Omalizumab as a  last resort therapy for intractable, severe chronic allergic rhinosinusitis
(Source: Allergo Journal International)
Source: Allergo Journal International - October 24, 2018 Category: Allergy & Immunology Source Type: research

Reminder system for adrenaline autoinjectors does not work
(Source: Allergo Journal International)
Source: Allergo Journal International - October 19, 2018 Category: Allergy & Immunology Source Type: research