What should be considered during epicutaneous patch testing?
AbstractIndications for epicutaneous patch testing include the detection or exclusion of allergic contact dermatitis of the skin, transitional mucosa or oral mucosa, suspected delayed-type immune reactions to ingredients of implants, and certain drug reactions (maculopapular exanthema, symmetrical drug-related intertriginous and flexural exanthema [SDRIFE], acute generalized exanthematous pustulosis [AGEP], and fixed drug eruption). When available, allergen preparations that have been pharmaceutically tested and that are approved or marketable as medicinal products should be used. Existing diagnostic gaps can be closed by ...
Source: Allergo Journal International - February 2, 2023 Category: Allergy & Immunology Source Type: research

Patients with asthma consulting an allergist differ from those consulting a  pulmonologist
(Source: Allergo Journal International)
Source: Allergo Journal International - February 2, 2023 Category: Allergy & Immunology Source Type: research

Coronavirus infection in an unvaccinated atopic dermatitis patient under ongoing dupilumab therapy: eczema flare-up, but moderate COVID-19 symptoms
(Source: Allergo Journal International)
Source: Allergo Journal International - February 1, 2023 Category: Allergy & Immunology Source Type: research

Allergen immunotherapy in house dust mite-associated allergic rhinitis: efficacy of the 300  IR mite tablet
Conclusion Allergen immunotherapy with the 300 IR mite tablet is an effective treatment that relieves allergic symptoms, reduces the need for symptomatic medication, and improves the quality of life in both adults and adolescents with house dust mite-associated allergic rhinitis. At the same time, treatment with the 300 IR mite tablet is well tolerated. Mild to moderate reactions at the application site subside after a few days. (Source: Allergo Journal International)
Source: Allergo Journal International - January 31, 2023 Category: Allergy & Immunology Source Type: research

High pan-allergen content in mango and peach in Taiwan
ConclusionOur data suggest that peach and mango contain the highest levels of important pan-allergens among the 15  common fruits tested, which agrees with epidemiological data. (Source: Allergo Journal International)
Source: Allergo Journal International - January 23, 2023 Category: Allergy & Immunology Source Type: research

Avoidance measures for mite allergy —an update
AbstractHouse dust mites are a  major source of allergens in house dust and, thus, the main trigger of perennial allergic respiratory diseases [1–5]. Scientific research on the life cycle, diet, and reproductive behavior of dust mites and on the biology of mite allergens has uncovered mechanisms leading to the development of respiratory allergies and suggests measures that can minimize exposure to dust mite allergens. Here, we discuss the evidence linking house dust mite exposure and respiratory allergies and present the efficacy of avoidance measures and their scientific evidence. (Source: Allergo Journal International)
Source: Allergo Journal International - January 23, 2023 Category: Allergy & Immunology Source Type: research

Validity of anamnestic data on allergies towards β-lactam antibiotics in a preoperative setting
(Source: Allergo Journal International)
Source: Allergo Journal International - January 10, 2023 Category: Allergy & Immunology Source Type: research

Safety in switching Hymenoptera venom immunotherapy manufacturers
(Source: Allergo Journal International)
Source: Allergo Journal International - December 30, 2022 Category: Allergy & Immunology Source Type: research

Efficacy and safety of medications for antihistamine-refractory chronic spontaneous urticaria: a  systematic review and network meta-analysis
ConclusionOmalizumab 300  mg injected every 4 weeks and cyclosporine 3–5 mg/kg daily per os are the most effective currently available drugs for antihistamine-refractory CSU. Cyclosporine shows a relatively less favorable safety profile. (Source: Allergo Journal International)
Source: Allergo Journal International - December 21, 2022 Category: Allergy & Immunology Source Type: research

Papuloerythroderma of Ofuji (PEO) successfully treated with acitretin
(Source: Allergo Journal International)
Source: Allergo Journal International - December 1, 2022 Category: Allergy & Immunology Source Type: research

Localized eczematous rash affecting left and right regions of breast and shoulder after Ad26.COV2.S vaccine against COVID-19 in a  30-year-old woman with comorbidities
(Source: Allergo Journal International)
Source: Allergo Journal International - November 28, 2022 Category: Allergy & Immunology Source Type: research

Allergen characteristics, quality, major allergen content and galenics for mite allergen-specific immunotherapy preparations
SummaryHouse dust mite extracts for allergen-specific immunotherapy (AIT) require in Germany as other common allergens (pollen from sweet grasses [except maize], birch, alder, hazel; bee and wasp venom) marketing authorisation according to the German Therapy Allergen Ordinance ( “Therapieallergene-Verordnung”, [TAV]). Mite allergen extracts that have been approved and also those which are in the approval process are subject to government batch testing. Batch test passing is a prerequisite for marketability. Appropriate quality, efficacy, and safety are prerequisites fo r the approval of house dust mite extracts. Five ...
Source: Allergo Journal International - November 24, 2022 Category: Allergy & Immunology Source Type: research

Clinic and diagnostics of house dust mite allergy
SummaryHouse dust mite allergens are common triggers for allergic rhinoconjunctivitis and allergic asthma; they can aggravate atopic dermatitis and rarely lead to anaphylactic reactions due to dust mite allergens in food. Typical symptoms are nasal obstruction, sneezing, and irritation, and more often than in pollen allergy, allergic asthma also develops. The symptomatology exists in principle throughout the year with maximum complaints in autumn and winter. Of particular importance are sleep disturbances due to nasal obstruction, which lead to restrictions in the quality of life and performance of affected patients. Sensi...
Source: Allergo Journal International - November 24, 2022 Category: Allergy & Immunology Source Type: research

Biology of house dust mites and storage mites
SummaryHouse dust mites and storage mites have a  high allergenic potential and lead to sensitization through the formation of specific IgE antibodies. Due to their preferred residence in houses, they belong to the group of house mites, which are referred to as “domestic mites” in English. Their anatomy and biology account for their amazing a daptability to changing environmental situations (including temperature, humidity, food) and make it understandable that measures to reduce their abundance are usually difficult to implement in practice. (Source: Allergo Journal International)
Source: Allergo Journal International - November 15, 2022 Category: Allergy & Immunology Source Type: research

Frequency of sensitizations and allergies to house dust mites
SummaryDomestic mites is the term used to describe dust mites and storage mites that prefer to live in houses and to which many people develop sensitization through the formation of specific IgE antibodies due to the high allergenic potency of mite allergens. As a  result, mites can trigger allergic diseases of the upper and lower respiratory tract as well as cross-reactions to other allergens. Sensitization to house mites is widespread in the German population. About 11 million adults are sensitized in Germany (15.9%). Men are more frequently affected than women, and sensitizations occur more frequently in large cities ...
Source: Allergo Journal International - November 7, 2022 Category: Allergy & Immunology Source Type: research