ARIA guideline 2019: treatment of allergic rhinitis in the German health system
DiscussionA  comprehensive ICP guideline can reflect real-life care better than traditional guideline models. (Source: Allergo Journal International)
Source: Allergo Journal International - October 21, 2019 Category: Allergy & Immunology Source Type: research

Drug-induced anaphylaxis —elicitors, mechanisms and diagnosis
AbstractDrugs are one of the major causes of anaphylaxis. For example 2346  cases of drug-induced anaphylaxis were reported to the anaphylaxis register as of March 2019. The most common triggers of drug-induced anaphylaxis were nonsteroidal anti-inflammatory drugs (NSAIDs;n = 902) and antibiotics (n = 721). Drug-induced anaphylaxis can be caused by IgE-dependent (e.g., penicillins) and IgE-independent mechanisms. Recently MRG-PX2 has been identified as a receptor for non-IgE-dependent mechanisms. Drug-induced anaphylaxis results more frequently in lethal reactions and is more commonly as sociated with cardiovasc...
Source: Allergo Journal International - October 16, 2019 Category: Allergy & Immunology Source Type: research

Characterization of a  cohort of storage mite sensitized subjects
ConclusionsSM are a  common sensitization in the study population and should be included in standard skin prick test arrays. Cross sensitization to house dust mites is limited and nasal symptoms are most frequent. Nasal provocation testing is necessary to secure clinical diagnosis of allergy and further research is ne eded to evaluate the clinical relevance of the high sensitization rates found for intradermal testing. (Source: Allergo Journal International)
Source: Allergo Journal International - October 9, 2019 Category: Allergy & Immunology Source Type: research

Ash pollen allergy and aerobiology
ConclusionSymptoms in individuals sensitized to ash pollen vary according to the pollen count and may be masked by pollen from other trees that flower at the same time of year. Sensitization to ash/Ole  e 1 can be higher than to birch/Bet v 1. The determination of IgE to common ash (Fraxinus excelsior) is more sensitive than to American ash (Fraxinus americana). Ash dieback due to Chalara appears to increase pollen emission. Allergies to ash pollen can be significantly underestimated due to a  failure to (correctly) identify them; they can also be masked by other pollen families (birch). Harmful organisms such as Chal...
Source: Allergo Journal International - September 29, 2019 Category: Allergy & Immunology Source Type: research

Correction to: Guideline on diagnostic procedures for suspected hypersensitivity to beta-lactam antibiotics
Correction to:Allergo J Int 2019https://doi.org/10.1007/s40629-019-0100-8In the “Guideline on diagnostic procedures for suspected hypersensitivity to beta-lactam antibiotics” Figs. 5 and 6 (allergy passports) are in German. Here you will find the allergy passports in … (Source: Allergo Journal International)
Source: Allergo Journal International - September 18, 2019 Category: Allergy & Immunology Source Type: research

Abstracts of the 14th German Allergy Congress
(Source: Allergo Journal International)
Source: Allergo Journal International - August 28, 2019 Category: Allergy & Immunology Source Type: research

IgE-mediated hypersensitivity to chlorhexidine among first-year dental students
ConclusionsAlthough most participants reported no known exposure to CHX, 8.6% showed CHX sensitisation suggesting unknown exposure and the potential risk of developing hypersensitivity and adverse reactions in the future. (Source: Allergo Journal International)
Source: Allergo Journal International - August 11, 2019 Category: Allergy & Immunology Source Type: research

Guideline on diagnostic procedures for suspected hypersensitivity to beta-lactam antibiotics
AbstractThis guideline on diagnostic procedures for suspected beta-lactam antibiotic (BLA) hypersensitivity was written by the German and Austrian professional associations for allergology, and the Paul-Ehrlich Society for Chemotherapy in a  consensus procedure according to the criteria of the German Association of Scientific Medical Societies. BLA such as penicillins and cephalosporins represent the drug group that most frequently triggers drug allergies. However, the frequency of reports of suspected allergy in patient histories cle arly exceeds the number of confirmed cases. The large number of suspected BLA allergies ...
Source: Allergo Journal International - July 21, 2019 Category: Allergy & Immunology Source Type: research

What we learned from TAO – 10 years of German therapy allergen ordinance
ConclusionsIn Germany, TAO ensures that all previously untested named patient products for the treatment of frequent allergies are subjected to an assessment of their risk/benefit ratio according to the current state of science. (Source: Allergo Journal International)
Source: Allergo Journal International - July 14, 2019 Category: Allergy & Immunology Source Type: research

Correction to: Air pollutants and primary allergy prevention
Correction to:Allergo J Int 2018https://doi.org/10.1007/s40629-018-0078-7An error was identified in the review on “Air pollutants and primary allergy prevention”. The given PM2.5 increment of 2  µg/m3 was wrong and should be replaced with an increment of 5  µg/m3.This was the case on:Page  9, legend … (Source: Allergo Journal International)
Source: Allergo Journal International - June 26, 2019 Category: Allergy & Immunology Source Type: research

Atopic eczema score of emotional consequences —a questionnaire to assess emotional consequences of atopic eczema
ConclusionAESEC is a  questionnaire for assessing the emotional consequences of living with AE. It may prove useful in evaluating the burden of disease, beyond skin symptoms and time-specific quality of life. (Source: Allergo Journal International)
Source: Allergo Journal International - June 2, 2019 Category: Allergy & Immunology Source Type: research

Update of reference values for IgG antibodies against typical antigens of hypersensitivity pneumonitis
DiscussionIn most cases specific IgG values were not significantly influenced by smoking and gender and most of them were unaffected by age. For implementation of these sIgG reference values into the routine diagnosis of HP, we provide an online available calculator to rank measured sIgG concentrations to the 32 different ImmunoCAP antigens. (Source: Allergo Journal International)
Source: Allergo Journal International - May 26, 2019 Category: Allergy & Immunology Source Type: research

Development of subcutaneous allergen immunotherapy (part  2): preventive aspects and innovations
ConclusionSCIT preparations are among the most innovative treatment options in the immunotherapy of allergic diseases. Due to the numerous immunological approaches, they will make treatment safer and more effective in the future with reduced effort. (Source: Allergo Journal International)
Source: Allergo Journal International - May 12, 2019 Category: Allergy & Immunology Source Type: research

German pollen calendar 4.0: update of the regional pollen calendars 4.0 with measurement data for the period 2011 –2016
(Source: Allergo Journal International)
Source: Allergo Journal International - May 1, 2019 Category: Allergy & Immunology Source Type: research

Effectiveness of a  portable air filtration device in reducing allergen exposure during household chores
DiscussionTypical household chores can result in high levels of exposure to indoor dust and allergens. The use of an AP however can reduce the inhalable dust concentrations, but the effect on allergen exposure was in most cases not large enough to achieve statistical significance. (Source: Allergo Journal International)
Source: Allergo Journal International - April 28, 2019 Category: Allergy & Immunology Source Type: research