Current developments in the treatment of peanut allergy
AbstractPeanut allergy is a potentially life-threatening disease because it leads to severe allergic reactions, especially in children but also in adults. So far, allergen avoidance is the most effective therapy for treating peanut allergy. In this article, current developments of peanut allergy specific immunotherapy are cr itically discussed based on the existing literature. These include sublingual, epicutaneous and oral peanut immunotherapy. Nonspecific treatment approaches with new-targeted antibodies such as anti-IgE (omalizumab) or anti-IL-4/IL-13 receptor antibodies (dupilumab) can also be used to treat peanut a ...
Source: Allergo Journal International - February 24, 2021 Category: Allergy & Immunology Source Type: research
Severe allergic reactions after COVID-19 vaccination with the Pfizer/BioNTech vaccine in Great Britain and USA
SummaryTwo employees of the National Health Service (NHS) in England developed severe allergic reactions following administration of BNT162b2 vaccine against COVID-19 (coronavirus disease 2019). The British SmPC for the BNT162b2 vaccine already includes reference to a contraindication for use in individuals who have had an allergic reaction to the vaccine or any of its components. As a precautionary measure, the Medicines and Healthcare products Regulatory Agency (MHRA) has issued interim guidance to the NHS not to vaccinate in principle in “patients with se vere allergies”. Allergic reactions to vaccines are very r...
Source: Allergo Journal International - February 24, 2021 Category: Allergy & Immunology Source Type: research
Telemedicine in allergology: practical aspects
AbstractSince spring 2020, the wide-ranging contact restriction measures in the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have also led to a reduction in physician–patient contacts in the ambulatory care setting. Telemedicine applications will increasingly provide a way to efficiently deliver patient care under infection control measures. In allergology, telemedical as well as digital applications can also significantly facilitate e veryday clinical practice. However, the technical and legal hurdles associated with the implementation of digital strategies must be overcome for...
Source: Allergo Journal International - February 22, 2021 Category: Allergy & Immunology Source Type: research
Targeted micronutrition via holo-BLG based on the farm effect in house dust mite allergic rhinoconjunctivitis patients – first evaluation in a standardized allergen exposure chamber
ConclusionsThe effect of holo-BLG resulting in immune resilience might help to fight the allergy epidemic on a new front based on targeted micronutrition of immune cells.Trial registrationThe study was retrospectively registered at clinicaltrials.gov (NCT04477382). (Source: Allergo Journal International)
Source: Allergo Journal International - February 22, 2021 Category: Allergy & Immunology Source Type: research
Guideline (S2k) on acute therapy and management of anaphylaxis: 2021 update
(Source: Allergo Journal International)
Source: Allergo Journal International - January 28, 2021 Category: Allergy & Immunology Source Type: research
Allergenic pollen: is it also an indoor problem?
(Source: Allergo Journal International)
Source: Allergo Journal International - January 28, 2021 Category: Allergy & Immunology Source Type: research
Tablet allergen immunotherapy (TAIT) requires tight management
(Source: Allergo Journal International)
Source: Allergo Journal International - January 11, 2021 Category: Allergy & Immunology Source Type: research
A gender-specific approach to occupational allergic contact dermatitis
ConclusionGender-distribution in OACD reflects differences in occupations with respect to men and women as evidenced by working sectors and haptens involved in the pathogenesis. (Source: Allergo Journal International)
Source: Allergo Journal International - December 17, 2020 Category: Allergy & Immunology Source Type: research
House dust mite immunotherapy in Germany: real-world adherence to a subcutaneous allergoid and a sublingual tablet
ConclusionIn this retrospective real-world cohort analysis in Germany, patients on subcutaneous AIT for HDM respiratory allergy achieved significantly higher adherence rates compared to the HDM-SLIT tablet over a 3-year treatment period. In addition, days on therapy were significantly higher for SCIT than for SLIT. It was shown that in real life significantly more patients receiving SCIT stay on the recommended treatment period of 3 years compared to SLIT subjects. This is important since effectiveness ha s been demonstrated to be linked with therapy duration. (Source: Allergo Journal International)
Source: Allergo Journal International - December 17, 2020 Category: Allergy & Immunology Source Type: research
Rapid protocol for irinotecan desensitization: a case report and literature review
(Source: Allergo Journal International)
Source: Allergo Journal International - December 10, 2020 Category: Allergy & Immunology Source Type: research
Healthcare provision for insect venom allergy patients during the COVID-19 pandemic
AbstractThe population prevalence of insect venom allergy ranges between 3 –5%, and it can lead to potentially life-threatening allergic reactions. Patients who have experienced a systemic allergic reaction following an insect sting should be referred to an allergy specialist for diagnosis and treatment. Due to the widespread reduction in outpatient and inpatient care c apacities in recent months as a result of the COVID-19 pandemic, the various allergy specialized centers in Germany, Austria, and Switzerland have taken different measures to ensure that patients with insect venom allergy will continue to receive optima...
Source: Allergo Journal International - December 8, 2020 Category: Allergy & Immunology Source Type: research
How will climate change alter the dynamics of airborne pollen and pollen load of allergenic plants?
ConclusionThe assumption that climate warming in Linz over 26 years should have increased pollen concentrations of allergenic plants was not confirmed. On the contrary, trend analyses showed that the pollen load has decreased. Hence, the increase in sensitization to pollen allergens and of the prevalence of pollen allergies ask for other explanations. (Source: Allergo Journal International)
Source: Allergo Journal International - December 8, 2020 Category: Allergy & Immunology Source Type: research
Health care situation in patients with allergic respiratory diseases with special focus on specific immunotherapy
ConclusionAnalysis of the care situation with regard to the specific immunotherapy in cases of allergic respiratory diseases (VerSITA) provides a solid basis for future research and for informing decision-makers in order to develop measures to optimize care. (Source: Allergo Journal International)
Source: Allergo Journal International - November 20, 2020 Category: Allergy & Immunology Source Type: research
Airlines provide too little information for allergy sufferers!
DiscussionThe information offered by many airlines for passengers with allergies is insufficient. To offer greater guidance, updated information has been formulated in German and English, and its use is recommended. (Source: Allergo Journal International)
Source: Allergo Journal International - November 20, 2020 Category: Allergy & Immunology Source Type: research
Marker allergens in Hymenoptera venom al lergy — Characteristics and potential use in precision medicine
AbstractBackgroundA comprehensive diagnostic work-up is essential to ensure adequate patient management for the potentially life-threatening condition of Hymenoptera venom allergy (HVA). This includes an unambiguous identification of the allergy-relevant venom as prerequisite for successful venom-specific immunothera py (VIT). If the clinical history does not allow the identification of the culprit insect, diagnosis is often hampered by positive test results to various venoms. Modern component-resolved diagnostics (CRD) applying marker allergens of Hymenoptera venoms has created new opportunities which facilitat e therap...
Source: Allergo Journal International - November 17, 2020 Category: Allergy & Immunology Source Type: research
