Active Breathing Coordinator reduces radiation dose to the stomach in patients with left breast cancer
CONCLUSIONS: The implementation of ABC-DIBH in LSBCPs radiotherapy resulted in lower irradiation of the stomach. Larger stomach volume was associated with statistically significantly higher dose irradiation in FB mode. To reduce radiotherapy related side effects in FB mode, patients should be fast for at least 2 hours before the CT simulation and treatment.PMID:37909907 | DOI:10.1080/0284186X.2023.2275288 (Source: Acta Oncologica)
Source: Acta Oncologica - November 1, 2023 Category: Cancer & Oncology Authors: Ying Piao Hongtao Chen Fengshun Yuan Juan Fan Shihai Wu Xianming Li Dong Yang Source Type: research

Co-occurrence of symptoms after radiochemotherapy in locally advanced cervix cancer patients: a cluster analysis
CONCLUSIONS: This analysis on both PRO and physician-assessed morbidity found a cluster associated with general symptoms and organ-related symptom clusters (urinary, gastrointestinal, vaginal). This shows that LACC survivors experience a variety of co-occurring symptoms. Our analysis also shows that the cluster of general symptoms is associated with a decrease in QOL.PMID:37906286 | DOI:10.1080/0284186X.2023.2271252 (Source: Acta Oncologica)
Source: Acta Oncologica - October 31, 2023 Category: Cancer & Oncology Authors: Marta Pelizzola Kari Tanderup Supriya Chopra Ina M J ürgenliemk-Schulz Remi Nout Kathrin Kirchheiner Sofia Spampinato Source Type: research

Clinical implication of genetic intratumor heterogeneity for targeted therapy in head and neck cancer
Conclusion: In 36% of patients diagnosed with HNSCC, clinically significant intratumor heterogeneity was observed which may have implications for patient management. This finding substantiates the need for future studies that specifically investigate the clinical implications associated with intratumor heterogeneity.PMID:37902999 | DOI:10.1080/0284186X.2023.2272293 (Source: Acta Oncologica)
Source: Acta Oncologica - October 30, 2023 Category: Cancer & Oncology Authors: Signe Buhl Gram Daniela Alosi Frederik Otzen Bagger Olga Østrup Christian von Buchwald Jeppe Friborg Irene Wessel Ivan Richter Vogelius Kristoffer Rohrberg Jacob H øygaard Rasmussen Source Type: research

Does the ypTNM-stage adequately predict long-term survival rates in gastric cancer patients receiving neoadjuvant chemotherapy followed by radical resection?
CONCLUSIONS: Survival curves for specific ypTNM-stages following NAC did not differ from the corresponding survival curves of their chemo-naïve pTNM counterparts. The interpretation is that NAC affected the gastric cancer, lymph nodes, and micrometastases, in such a way that the final ypTNM-stage provided similar prognostic information as the chemo-naïve pTNM-stages. Survival rates were contingent on the final ypTNM-stages alone, and not influenced by the response mode to reach that particular disease stage, or predetermined by the original clinical TNM-stage.PMID:37903117 | DOI:10.1080/0284186X.2023.2274480 (Source: Acta Oncologica)
Source: Acta Oncologica - October 30, 2023 Category: Cancer & Oncology Authors: Alina Desiree Sand ø Jon Erik Gr ønbech Erling Audun Bringeland Source Type: research

Clinical implication of genetic intratumor heterogeneity for targeted therapy in head and neck cancer
Conclusion: In 36% of patients diagnosed with HNSCC, clinically significant intratumor heterogeneity was observed which may have implications for patient management. This finding substantiates the need for future studies that specifically investigate the clinical implications associated with intratumor heterogeneity.PMID:37902999 | DOI:10.1080/0284186X.2023.2272293 (Source: Acta Oncologica)
Source: Acta Oncologica - October 30, 2023 Category: Cancer & Oncology Authors: Signe Buhl Gram Daniela Alosi Frederik Otzen Bagger Olga Østrup Christian von Buchwald Jeppe Friborg Irene Wessel Ivan Richter Vogelius Kristoffer Rohrberg Jacob H øygaard Rasmussen Source Type: research

Does the ypTNM-stage adequately predict long-term survival rates in gastric cancer patients receiving neoadjuvant chemotherapy followed by radical resection?
CONCLUSIONS: Survival curves for specific ypTNM-stages following NAC did not differ from the corresponding survival curves of their chemo-naïve pTNM counterparts. The interpretation is that NAC affected the gastric cancer, lymph nodes, and micrometastases, in such a way that the final ypTNM-stage provided similar prognostic information as the chemo-naïve pTNM-stages. Survival rates were contingent on the final ypTNM-stages alone, and not influenced by the response mode to reach that particular disease stage, or predetermined by the original clinical TNM-stage.PMID:37903117 | DOI:10.1080/0284186X.2023.2274480 (Source: Acta Oncologica)
Source: Acta Oncologica - October 30, 2023 Category: Cancer & Oncology Authors: Alina Desiree Sand ø Jon Erik Gr ønbech Erling Audun Bringeland Source Type: research

Real-world analysis of MET exon 14 mutations in non-small cell lung cancer: a retrospective study from two Swedish hospitals
CONCLUSIONS: Our data suggest limited survival benefits from METi, ICIs, and chemotherapy for METex14 lung cancer patients. While not statistically significant, these findings underscore the need for larger trials for validation. Identifying effective treatments for this challenging lung cancer subtype remains a priority.PMID:37897706 | DOI:10.1080/0284186X.2023.2269310 (Source: Acta Oncologica)
Source: Acta Oncologica - October 28, 2023 Category: Cancer & Oncology Authors: Marcus Skribek Hans Brunnstr öm Gudrun Oskarsdottir Mikel Portu Griv é Ozan Aricak Maria Planck Kenbugul Jatta Homeyra Naserhojati Felix Haglund de Flon Simon Ekman Source Type: research

Most common health problems in general practice among adolescents, and young adults' survivors of lymphoma: a register-based cohort study in Norway
CONCLUSION: Compared to the general population, young lymphoma survivors have increased contact with the GP for a considerable number of health problems for up to 10 years post-diagnosis. This emphasizes the importance of robust follow-up and a good flow of information between hospital and primary care.PMID:37897712 | DOI:10.1080/0284186X.2023.2273894 (Source: Acta Oncologica)
Source: Acta Oncologica - October 28, 2023 Category: Cancer & Oncology Authors: Ram Prasad Upreti Elia Mmbaga Hege Sagstuen Haugnes Cecilie E Kiserud Ruby Del Risco Kollerud Source Type: research

Timing of start of systemic treatment in patients with asymptomatic metastasized pancreatic cancer (TIMEPAN): a protocol of a multicenter prospective patient preference non-randomized trial
Acta Oncol. 2023 Oct 28:1-6. doi: 10.1080/0284186X.2023.2273898. Online ahead of print.NO ABSTRACTPMID:37897803 | DOI:10.1080/0284186X.2023.2273898 (Source: Acta Oncologica)
Source: Acta Oncologica - October 28, 2023 Category: Cancer & Oncology Authors: Simone Augustinus Thijmen Broekman Geert-Jan Creemers Lois A Daamen Susan van Dieren Jan-Willem B de Groot Geert A Cirkel Marjolein Y V Homs Hanneke W M van Laarhoven Lobke van Leeuwen Maartje Los Saskia A C Luelmo Martijn G H van Oijen Leontine E A M Spi Source Type: research

Real-world analysis of MET exon 14 mutations in non-small cell lung cancer: a retrospective study from two Swedish hospitals
CONCLUSIONS: Our data suggest limited survival benefits from METi, ICIs, and chemotherapy for METex14 lung cancer patients. While not statistically significant, these findings underscore the need for larger trials for validation. Identifying effective treatments for this challenging lung cancer subtype remains a priority.PMID:37897706 | DOI:10.1080/0284186X.2023.2269310 (Source: Acta Oncologica)
Source: Acta Oncologica - October 28, 2023 Category: Cancer & Oncology Authors: Marcus Skribek Hans Brunnstr öm Gudrun Oskarsdottir Mikel Portu Griv é Ozan Aricak Maria Planck Kenbugul Jatta Homeyra Naserhojati Felix Haglund de Flon Simon Ekman Source Type: research

Most common health problems in general practice among adolescents, and young adults' survivors of lymphoma: a register-based cohort study in Norway
CONCLUSION: Compared to the general population, young lymphoma survivors have increased contact with the GP for a considerable number of health problems for up to 10 years post-diagnosis. This emphasizes the importance of robust follow-up and a good flow of information between hospital and primary care.PMID:37897712 | DOI:10.1080/0284186X.2023.2273894 (Source: Acta Oncologica)
Source: Acta Oncologica - October 28, 2023 Category: Cancer & Oncology Authors: Ram Prasad Upreti Elia Mmbaga Hege Sagstuen Haugnes Cecilie E Kiserud Ruby Del Risco Kollerud Source Type: research

Timing of start of systemic treatment in patients with asymptomatic metastasized pancreatic cancer (TIMEPAN): a protocol of a multicenter prospective patient preference non-randomized trial
Acta Oncol. 2023 Oct 28:1-6. doi: 10.1080/0284186X.2023.2273898. Online ahead of print.NO ABSTRACTPMID:37897803 | DOI:10.1080/0284186X.2023.2273898 (Source: Acta Oncologica)
Source: Acta Oncologica - October 28, 2023 Category: Cancer & Oncology Authors: Simone Augustinus Thijmen Broekman Geert-Jan Creemers Lois A Daamen Susan van Dieren Jan-Willem B de Groot Geert A Cirkel Marjolein Y V Homs Hanneke W M van Laarhoven Lobke van Leeuwen Maartje Los Saskia A C Luelmo Martijn G H van Oijen Leontine E A M Spi Source Type: research

Pathology of MRI and second-look ultrasound detected multifocal breast cancer
CONCLUSION: In multifocal breast cancers, additional lesions detected on MRI and second-look US have the same or less invasive histopathology compared to the index lesion.PMID:37890095 | DOI:10.1080/0284186X.2023.2273897 (Source: Acta Oncologica)
Source: Acta Oncologica - October 27, 2023 Category: Cancer & Oncology Authors: Shu Su Jason C Ray Corinne Ooi Manish Jain Source Type: research

Pathology of MRI and second-look ultrasound detected multifocal breast cancer
CONCLUSION: In multifocal breast cancers, additional lesions detected on MRI and second-look US have the same or less invasive histopathology compared to the index lesion.PMID:37890095 | DOI:10.1080/0284186X.2023.2273897 (Source: Acta Oncologica)
Source: Acta Oncologica - October 27, 2023 Category: Cancer & Oncology Authors: Shu Su Jason C Ray Corinne Ooi Manish Jain Source Type: research

Script-based automatic radiotherapy planning for cervical cancer
CONCLUSION: The automatic plans had acceptable target coverage, lower doses to almost all OARs, more conformal dose distributions, and were predominantly preferred by the clinicians. Based on these results, our institution has implemented the script for clinical use.PMID:37881003 | DOI:10.1080/0284186X.2023.2267171 (Source: Acta Oncologica)
Source: Acta Oncologica - October 26, 2023 Category: Cancer & Oncology Authors: Marit Funderud Ingvild Straumsheim Hoem Marte Anette Dunseth Guleng Monika Eidem Sigrun Saur Almberg Mirjam Delange Alsaker Josefine St åhl-Kornerup Jomar Frengen Anne Beate Langeland Marthinsen Source Type: research