Radiotherapy with or without immunotherapy in metastatic melanoma: efficacy and Tolerability
CONCLUSION: This retrospective study showed that melanoma patients receiving RT in combination with ICI had a superior antitumoral response in both irradiated and non-irradiated lesions as compared to patients receiving only RT. Additionally, a subgroup of patients receiving RT when progressing on ICI experienced tumor regression also in non-irradiated areas.PMID:37966921 | DOI:10.1080/0284186X.2023.2280766 (Source: Acta Oncologica)
Source: Acta Oncologica - November 15, 2023 Category: Cancer & Oncology Authors: Ellen Backlund Vitali Grozman Suzanne Egyhazi Brage Rolf Lewensohn Karin Lindberg Hildur Helgadottir Source Type: research
Surgical decision-making following neoadjuvant immunotherapy for dMMR rectal cancer; case reports and review of the literature
Acta Oncol. 2023 Nov 15:1-7. doi: 10.1080/0284186X.2023.2281005. Online ahead of print.NO ABSTRACTPMID:37966970 | DOI:10.1080/0284186X.2023.2281005 (Source: Acta Oncologica)
Source: Acta Oncologica - November 15, 2023 Category: Cancer & Oncology Authors: Mef Nilbert Jakob Eberhard Jenny Engdahl Severin Marcus Edelhamre Filip Torle Dejan Korkocic Fredrik J örgren Source Type: research
Radiotherapy with or without immunotherapy in metastatic melanoma: efficacy and Tolerability
CONCLUSION: This retrospective study showed that melanoma patients receiving RT in combination with ICI had a superior antitumoral response in both irradiated and non-irradiated lesions as compared to patients receiving only RT. Additionally, a subgroup of patients receiving RT when progressing on ICI experienced tumor regression also in non-irradiated areas.PMID:37966921 | DOI:10.1080/0284186X.2023.2280766 (Source: Acta Oncologica)
Source: Acta Oncologica - November 15, 2023 Category: Cancer & Oncology Authors: Ellen Backlund Vitali Grozman Suzanne Egyhazi Brage Rolf Lewensohn Karin Lindberg Hildur Helgadottir Source Type: research
Surgical decision-making following neoadjuvant immunotherapy for dMMR rectal cancer; case reports and review of the literature
Acta Oncol. 2023 Nov 15:1-7. doi: 10.1080/0284186X.2023.2281005. Online ahead of print.NO ABSTRACTPMID:37966970 | DOI:10.1080/0284186X.2023.2281005 (Source: Acta Oncologica)
Source: Acta Oncologica - November 15, 2023 Category: Cancer & Oncology Authors: Mef Nilbert Jakob Eberhard Jenny Engdahl Severin Marcus Edelhamre Filip Torle Dejan Korkocic Fredrik J örgren Source Type: research
Evaluation of tumor-infiltrating lymphocytes, PD-L1, and < em > PIK3CA < /em > mutations and association with prognosis in HER2-positive early stage breast cancer
DISCUSSION: Patients with low sTILs had a significantly poorer survival, despite adequate treatment with adjuvant therapy.PMID:37961947 | DOI:10.1080/0284186X.2023.2279685 (Source: Acta Oncologica)
Source: Acta Oncologica - November 14, 2023 Category: Cancer & Oncology Authors: Frances M Reznitsky Jeanette D Jensen Ann Knoop Maj-Britt Jensen Anne-Vibeke Laenkholm Source Type: research
Evaluation of tumor-infiltrating lymphocytes, PD-L1, and < em > PIK3CA < /em > mutations and association with prognosis in HER2-positive early stage breast cancer
DISCUSSION: Patients with low sTILs had a significantly poorer survival, despite adequate treatment with adjuvant therapy.PMID:37961947 | DOI:10.1080/0284186X.2023.2279685 (Source: Acta Oncologica)
Source: Acta Oncologica - November 14, 2023 Category: Cancer & Oncology Authors: Frances M Reznitsky Jeanette D Jensen Ann Knoop Maj-Britt Jensen Anne-Vibeke Laenkholm Source Type: research
Evaluating video-based consultations in routine clinical practice at a comprehensive cancer center
CONCLUSION: This study showed promising results of incorporating video-based teleconsultations into cancer patient management. Randomized clinical trials are needed in order to accelerate the digital implementation in clinical practice.PMID:37948066 | DOI:10.1080/0284186X.2023.2278758 (Source: Acta Oncologica)
Source: Acta Oncologica - November 10, 2023 Category: Cancer & Oncology Authors: Thibaut Mottet Victor H émar Sylvia Enfedaque Simone Mathoulin-P élissier H élène Charitansky Yann Godbert Guilhem Roubaud Mathilde Cabart Camille Chakiba Fran çois Chomy Laura Haik Nicolas Le Dantec Wafa Bouleftour Nicolas Magn é Nathalie Quenel Tu Source Type: research
Evaluating video-based consultations in routine clinical practice at a comprehensive cancer center
CONCLUSION: This study showed promising results of incorporating video-based teleconsultations into cancer patient management. Randomized clinical trials are needed in order to accelerate the digital implementation in clinical practice.PMID:37948066 | DOI:10.1080/0284186X.2023.2278758 (Source: Acta Oncologica)
Source: Acta Oncologica - November 10, 2023 Category: Cancer & Oncology Authors: Thibaut Mottet Victor H émar Sylvia Enfedaque Simone Mathoulin-P élissier H élène Charitansky Yann Godbert Guilhem Roubaud Mathilde Cabart Camille Chakiba Fran çois Chomy Laura Haik Nicolas Le Dantec Wafa Bouleftour Nicolas Magn é Nathalie Quenel Tu Source Type: research
Evaluating video-based consultations in routine clinical practice at a comprehensive cancer center
CONCLUSION: This study showed promising results of incorporating video-based teleconsultations into cancer patient management. Randomized clinical trials are needed in order to accelerate the digital implementation in clinical practice.PMID:37948066 | DOI:10.1080/0284186X.2023.2278758 (Source: Acta Oncologica)
Source: Acta Oncologica - November 10, 2023 Category: Cancer & Oncology Authors: Thibaut Mottet Victor H émar Sylvia Enfedaque Simone Mathoulin-P élissier H élène Charitansky Yann Godbert Guilhem Roubaud Mathilde Cabart Camille Chakiba Fran çois Chomy Laura Haik Nicolas Le Dantec Wafa Bouleftour Nicolas Magn é Nathalie Quenel Tu Source Type: research
Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer < em > EGFR < /em > Exon 20 insertion mutations after platinum-based chemotherapy
CONCLUSION: In the absence of clinical evidence from randomized clinical trials, this study reflects the benefit of amivantamab after platinum-based chemotherapy for advanced non-small cell lung cancer patients harboring EGFR Exon 20ins, compared to current real-world therapies.PMID:37938161 | DOI:10.1080/0284186X.2023.2254479 (Source: Acta Oncologica)
Source: Acta Oncologica - November 8, 2023 Category: Cancer & Oncology Authors: Tae Min Kim Nicolas Girard Grace Kah Mun Low Jianmin Zhuo Dae Young Yu Yishen Yang Maiko Murota Cindy Thiow Koon Lim Nora J Kleinman Byoung Chul Cho Source Type: research
Altered p53/p16 expression is linked to urothelial carcinoma progression but largely unrelated to prognosis in muscle-invasive tumors
CONCLUSION: Aberrant p53 and p16 immunostaining increases during grade and stage progression although p53 negative and p16 positive immunostaining lack prognostic significance in pT2-4 carcinomas. Potential diagnostic features are that high level p16 expression is limited to neoplastic urothelium and p53 null phenotype to aggressive cancers (grade 3 and invasive).PMID:37938166 | DOI:10.1080/0284186X.2023.2277344 (Source: Acta Oncologica)
Source: Acta Oncologica - November 8, 2023 Category: Cancer & Oncology Authors: Simon Schallenberg Henning Plage Sebastian Hofbauer Kira Furlano Sarah Weinberger Paul Giacomo Bruch Florian Ro ßner Sefer Elezkurtaj Martina Kluth Maximilian Lennartz Niclas C Blessin Andreas H Marx Henrik Samtleben Margit Fisch Michael Rink Marcin Sloj Source Type: research
Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer < em > EGFR < /em > Exon 20 insertion mutations after platinum-based chemotherapy
CONCLUSION: In the absence of clinical evidence from randomized clinical trials, this study reflects the benefit of amivantamab after platinum-based chemotherapy for advanced non-small cell lung cancer patients harboring EGFR Exon 20ins, compared to current real-world therapies.PMID:37938161 | DOI:10.1080/0284186X.2023.2254479 (Source: Acta Oncologica)
Source: Acta Oncologica - November 8, 2023 Category: Cancer & Oncology Authors: Tae Min Kim Nicolas Girard Grace Kah Mun Low Jianmin Zhuo Dae Young Yu Yishen Yang Maiko Murota Cindy Thiow Koon Lim Nora J Kleinman Byoung Chul Cho Source Type: research
Altered p53/p16 expression is linked to urothelial carcinoma progression but largely unrelated to prognosis in muscle-invasive tumors
CONCLUSION: Aberrant p53 and p16 immunostaining increases during grade and stage progression although p53 negative and p16 positive immunostaining lack prognostic significance in pT2-4 carcinomas. Potential diagnostic features are that high level p16 expression is limited to neoplastic urothelium and p53 null phenotype to aggressive cancers (grade 3 and invasive).PMID:37938166 | DOI:10.1080/0284186X.2023.2277344 (Source: Acta Oncologica)
Source: Acta Oncologica - November 8, 2023 Category: Cancer & Oncology Authors: Simon Schallenberg Henning Plage Sebastian Hofbauer Kira Furlano Sarah Weinberger Paul Giacomo Bruch Florian Ro ßner Sefer Elezkurtaj Martina Kluth Maximilian Lennartz Niclas C Blessin Andreas H Marx Henrik Samtleben Margit Fisch Michael Rink Marcin Sloj Source Type: research
Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer < em > EGFR < /em > Exon 20 insertion mutations after platinum-based chemotherapy
CONCLUSION: In the absence of clinical evidence from randomized clinical trials, this study reflects the benefit of amivantamab after platinum-based chemotherapy for advanced non-small cell lung cancer patients harboring EGFR Exon 20ins, compared to current real-world therapies.PMID:37938161 | DOI:10.1080/0284186X.2023.2254479 (Source: Acta Oncologica)
Source: Acta Oncologica - November 8, 2023 Category: Cancer & Oncology Authors: Tae Min Kim Nicolas Girard Grace Kah Mun Low Jianmin Zhuo Dae Young Yu Yishen Yang Maiko Murota Cindy Thiow Koon Lim Nora J Kleinman Byoung Chul Cho Source Type: research
Altered p53/p16 expression is linked to urothelial carcinoma progression but largely unrelated to prognosis in muscle-invasive tumors
CONCLUSION: Aberrant p53 and p16 immunostaining increases during grade and stage progression although p53 negative and p16 positive immunostaining lack prognostic significance in pT2-4 carcinomas. Potential diagnostic features are that high level p16 expression is limited to neoplastic urothelium and p53 null phenotype to aggressive cancers (grade 3 and invasive).PMID:37938166 | DOI:10.1080/0284186X.2023.2277344 (Source: Acta Oncologica)
Source: Acta Oncologica - November 8, 2023 Category: Cancer & Oncology Authors: Simon Schallenberg Henning Plage Sebastian Hofbauer Kira Furlano Sarah Weinberger Paul Giacomo Bruch Florian Ro ßner Sefer Elezkurtaj Martina Kluth Maximilian Lennartz Niclas C Blessin Andreas H Marx Henrik Samtleben Margit Fisch Michael Rink Marcin Sloj Source Type: research
