[ASAP] Targeting the “Undruggable” Driver Protein, KRAS < sup > G12D < /sup > , as Potential Therapy in Prostate Cancer
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00076 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 20, 2023 Category: Chemistry Authors: Robert B. Kargbo Source Type: research
[ASAP] Discovery of Potent Deuterated Compounds as Potential KRAS < sup > G12D < /sup > Inhibitors in Cancer Therapy
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00075 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 20, 2023 Category: Chemistry Authors: Robert B. Kargbo Source Type: research
[ASAP] A Shift in Thinking: Cellular Thermal Shift Assay-Enabled Drug Discovery
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00545 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 17, 2023 Category: Chemistry Authors: Isabel Marti ́n Caballero and Stina Lundgren Source Type: research
[ASAP] ChemBeads-Enabled Photoredox High-Throughput Experimentation Platform to Improve C(sp < sup > 2 < /sup > ) –C(sp < sup > 3 < /sup > ) Decarboxylative Couplings
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00538 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 16, 2023 Category: Chemistry Authors: Nathan J. Gesmundo, Noah P. Tu, Kathy A. Sarris, and Ying Wang Source Type: research
[ASAP] Relevance of the Trillion-Sized Chemical Space “eXplore” as a Source for Drug Discovery
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00021 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 16, 2023 Category: Chemistry Authors: Alexander Neumann, Lester Marrison, and Raphael Klein Source Type: research
[ASAP] Orally Active Forms of DMT, 5 ‑MeO-DMT, and Long-Acting MDMA for the Treatment of Neuropsychiatric Disorders
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00077 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 16, 2023 Category: Chemistry Authors: Robert B. Kargbo Source Type: research
[ASAP] Cyclic Peptidic Furin Inhibitors Developed by Combinatorial Chemistry
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00008 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 15, 2023 Category: Chemistry Authors: Agata Gitlin-Domagalska, Dawid De ̨bowski, Aleksandra Maciejewska, Sergey Samsonov, Martyna Maszota-Zieleniak, Natalia Ptaszyńska, Anna Łęgowska, and Krzysztof Rolka Source Type: research
[ASAP] The Identification of GPR52 Agonist HTL0041178, a Potential Therapy for Schizophrenia and Related Psychiatric Disorders
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00052 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 14, 2023 Category: Chemistry Authors: Simon Poulter, Nigel Austin, Rachel Armstrong, Matt Barnes, Sarah Joanne Bucknell, Alicia Higueruelo, Joydeep Banjaree, Andy Mead, Richard Mould, Cliona MacSweeney, M. Alistair O ’Brien, Lisa Alice Stott, and Stephen P. Watson Source Type: research
[ASAP] Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00530 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 14, 2023 Category: Chemistry Authors: Zachary W. Davis-Gilbert, Andreas Kra ̈mer, James E. Dunford, Stefanie Howell, Filiz Senbabaoglu, Carrow I. Wells, Frances M. Bashore, Tammy M. Havener, Jeffery L. Smith, Mohammad A. Hossain, Udo Oppermann, David H. Drewry, and Alison D. Axtman Source Type: research
[ASAP] Discovery of Futibatinib: The First Covalent FGFR Kinase Inhibitor in Clinical Use
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00006 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 10, 2023 Category: Chemistry Authors: Satoru Ito, Sachie Otsuki, Hirokazu Ohsawa, Atsushi Hirano, Hideki Kazuno, Satoshi Yamashita, Kosuke Egami, Yoshihiro Shibata, Ikuo Yamamiya, Fumiaki Yamashita, Yasuo Kodama, Kaoru Funabashi, Hiromi Kazuno, Toshiharu Komori, Satoshi Suzuki, Hiroshi Sootom Source Type: research
[ASAP] Constructive On-DNA Abramov Reaction and Pudovik Reaction for DEL Synthesis
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00022 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 10, 2023 Category: Chemistry Authors: Zhaomei Sun, Lingqian Xiao, Yahui Chen, Jiangying Wang, Fanming Zeng, Huanqing Zhang, Jie Zhang, Kexin Yang, and Yun Jin Hu Source Type: research
[ASAP] Rimonabant-Based Compounds Bearing Hydrophobic Amino Acid Derivatives as Cannabinoid Receptor Subtype 1 Ligands
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00024 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 9, 2023 Category: Chemistry Authors: Szabolcs Dvora ́cskó, Marilisa Pia Dimmito, Jessica Sebastiani, Giuseppe La Regina, Romano Silvestri, Stefano Pieretti, Azzurra Stefanucci, Csaba Tömböly, and Adriano Mollica Source Type: research
[ASAP] Accelerating Drug Discovery: Synthesis of Complex Chemotypes via Multicomponent Reactions
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00012 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 8, 2023 Category: Chemistry Authors: Melissa J. Buskes, Aaron Coffin, Dawn M. Troast, Rachel Stein, and Maria-Jesus Blanco Source Type: research
[ASAP] Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI)
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00069 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 8, 2023 Category: Chemistry Authors: Jane Aldrich, Shelley Allen, Erika Araujo, Joanne Bronson, Amanda Bryant-Friedrich, Shana K. Cyr, Erin F. DiMauro, Carolyn Dzierba, Amanda L. Garner, Gunda I. Georg, Nicole C. Goodwin, Krupanandan Haranahalli, Rong Huang, Katerina Leftheris, Tricia L. May Source Type: research
[ASAP] Design, Synthesis, and Bioevaluation of Dexmedetomidine Prodrug
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00449 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - March 6, 2023 Category: Chemistry Authors: Xin Li, Jingjing Zhang, Changcui Zhou, Rui Ling, Deying Gong, Yi Kang, Qingrong Qi, and Jun Yang Source Type: research
