[ASAP] Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00242 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - August 1, 2022 Category: Chemistry Authors: David Harrison, Mark G. Bock, John R. Doedens, Christopher A. Gabel, M. Katharine Holloway, Arwel Lewis, Jane Scanlon, Andrew Sharpe, Iain D. Simpson, Pamela Smolak, Grant Wishart, and Alan P. Watt Source Type: research
[ASAP] Novel IRAK4 Inhibitors for Treating Asthma
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00324 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 29, 2022 Category: Chemistry Authors: Ram W. Sabnis Source Type: research
[ASAP] Novel Plasma Kallikrein Inhibitors for Treating Hereditary Angioedema, Diabetic Macular Edema, and Diabetic Retinopathy
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00323 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 29, 2022 Category: Chemistry Authors: Ram W. Sabnis Source Type: research
[ASAP] Novel Tetrazole Derivatives as TRPA1 Inhibitors for Treating Idiopathic Lung Disease or Cough
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00322 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 29, 2022 Category: Chemistry Authors: Ram W. Sabnis Source Type: research
[ASAP] Novel RXFP1Modulators for Treating Heart Failure
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00321 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 29, 2022 Category: Chemistry Authors: Ram W. Sabnis Source Type: research
[ASAP] Identification of RAD51 –BRCA2 Inhibitors Using < italic toggle="yes" > N < /italic > ‑Acylhydrazone-Based Dynamic Combinatorial Chemistry
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00063 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 28, 2022 Category: Chemistry Authors: Greta Bagnolini, Beatrice Balboni, Fabrizio Schipani, Dario Gioia, Marina Veronesi, Francesca De Franco, Cansu Kaya7, Ravindra P. Jumde, Jose Antonio Ortega, Stefania Girotto, Anna K. H. Hirsch7, Marinella Roberti, and Andrea Cavalli Source Type: research
[ASAP] Application of Selective SMARCA2/4 PROTAC for Mutant Cancer Therapy
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00316 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 25, 2022 Category: Chemistry Authors: Robert B. Kargbo Source Type: research
[ASAP] BTZ-Derived Benzisothiazolinones with In Vitro Activity against < italic toggle="yes" > Mycobacterium tuberculosis < /italic >
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00215 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 25, 2022 Category: Chemistry Authors: Adrian Richter, Ru ̈diger W. Seidel, Richard Goddard, Tamira Eckhardt, Christoph Lehmann, Julia Dörner, Fabienne Siersleben, Theresia Sondermann, Lea Mann, Michael Patzer, Christian Jäger, Norbert Reiling, and Peter Imming Source Type: research
[ASAP] Quinolines and Oxazino-quinoline Derivatives as Small Molecule GLI1 Inhibitors Identified by Virtual Screening
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00249 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 22, 2022 Category: Chemistry Authors: Fabrizio Manetti, Luisa Maresca, Enrica Crivaro, Sara Pepe, Elena Cini, Snigdha Singh, Paolo Governa, Samuele Maramai, Giuseppe Giannini, Barbara Stecca, and Elena Petricci Source Type: research
[ASAP] Bisubstate Inhibitors of Severe Acute Respiratory Syndrome Coronavirus ‑2 Nsp14 Methyltransferase
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00265 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 22, 2022 Category: Chemistry Authors: Eunkyung Jung, Ruben Soto-Acosta, Jiashu Xie, Daniel J. Wilson, Christine D. Dreis, Ryuichi Majima, Tiffany C. Edwards, Robert J. Geraghty, and Liqiang Chen Source Type: research
[ASAP] Novel CA(1 –7)M(2–9) Analogs: Synthesis, Characterization, and Antibacterial Evaluation
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00270 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 21, 2022 Category: Chemistry Authors: Talia Chetty, Jessica T. Mhlongo, Ayman Y. Waddad, Fernando Albericio, and Beatriz G. de la Torre Source Type: research
[ASAP] Application of Degradation of Cyclic-AMP Response Element Binding Protein for the Potential Treatment of Cancer
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00317 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 21, 2022 Category: Chemistry Authors: Robert B. Kargbo Source Type: research
[ASAP] Discovery of Insulin/GLP-1/Glucagon Triagonists for the Treatment of Diabetes and Obesity
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00218 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 21, 2022 Category: Chemistry Authors: Chunhui Huang, Anandan Palani, Zhiqiang Yang, Qiaolin Deng, Vijay Reddy, Ravi P. Nargund, Songnian Lin, Simona Altezza, Elisabetta Bianchi, Federica Orvieto, and Paul Carrington Source Type: research
[ASAP] Discovery of MK-1462: GLP ‑1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00217 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 21, 2022 Category: Chemistry Authors: Anandan Palani, Andrea R. Nawrocki, Federica Orvieto, Elisabetta Bianchi, Emanuela Mandic ́, Antonello Pessi, Chunhui Huang, Qiaolin Deng, Nathalie Toussaint, Erika Walsh, Vijay Reddy, Eric Ashley, Huaibing He, Sheena Mumick, Brian Hawes, Donald Marsh, M Source Type: research
[ASAP] Therapeutic and Effective CURE-PRO Molecules for E3 Ligase-Mediated Targeted Protein Degradation
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00315 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 21, 2022 Category: Chemistry Authors: Robert B. Kargbo Source Type: research
