[ASAP] Incorporation of an Isohexide Subunit Improves the Drug-like Properties of Bioactive Compounds
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00476 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 20, 2023 Category: Chemistry Authors: Achyutharao Sidduri, Mark J. Dresel, and Spencer Knapp Source Type: research
[ASAP] Psychedelic-Assisted Neuroplasticity for the Treatment of Mental Health Disorders
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00546 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 18, 2023 Category: Chemistry Authors: Robert B. Kargbo Source Type: research
[ASAP] Macrocyclic Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonists
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00500 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 18, 2023 Category: Chemistry Authors: Mark E. Schnute, John I. Trujillo, Katherine L. Lee, Ray Unwalla, Felix F. Vajdos, Bjo ̈rn Kauppi, Philippe Nuhant, Andrew C. Flick, Kimberly K. Crouse, Yajuan Zhao, Amanda Samuel, Vincent Lombardo, Alexandria P. Taylor, Amy L. Brault, John D. Knafels, M Source Type: research
[ASAP] Plasma Kallikrein Inhibitors as Potential Treatment for Diabetic Macular Edema, Retinal Vein Occlusion, Hereditary Angioedema and Other Related Diseases
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00526 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 17, 2023 Category: Chemistry Authors: Ahmed F. Abdel-Magid Source Type: research
[ASAP] Inhibitors of Interleukin 4 Induced Protein 1 (IL4I1) as Potential Treatment for Cancer
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00525 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 17, 2023 Category: Chemistry Authors: Ahmed F. Abdel-Magid Source Type: research
[ASAP] A Quantum Mechanics-Based Method to Predict Intramolecular Hydrogen Bond Formation Reflecting P ‑glycoprotein Recognition
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00427 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 13, 2023 Category: Chemistry Authors: Takuya Oguma, Shota Uehara, Kenji Nakahara, Yuya Okuyama, Kouki Fuchino, Naoyuki Suzuki, Yukiko Kan, Naoki Kanegawa, Yuki Ogata, and Ken-ichi Kusakabe Source Type: research
[ASAP] Design, Synthesis, and Bioevaluation of Pyrido[2,3 ‑ < italic toggle="yes" > d < /italic > ]pyrimidin-7-ones as Potent SOS1 Inhibitors
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00490 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 12, 2023 Category: Chemistry Authors: Meiying Liu ▽, Guizhen Zhou▽, Wenhong Su▽, Yuejiao Gu, Mingshan Gao, Kun Wang, Ruifeng Huo, Yupeng Li, Zehui Zhou, Kaixian Chen, Mingyue Zheng, Sulin Zhang, and Tianfeng Xu Source Type: research
[ASAP] Discovery of OICR12694: A Novel, Potent, Selective, and Orally Biovailable BCL6 BTB Inhibitor
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00502 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 12, 2023 Category: Chemistry Authors: Ahmed Mamai, Anh M. Chau, Brian J. Wilson, Iain D. Watson, Babu B. Joseph, Pandiaraju R. Subramanian, Monzur M. Morshed, Justin A. Morin, Michael A. Prakesh, Tianbao Lu, Pete Connolly, Douglas A. Kuntz, Neil C. Pomroy, Gennady Poda, Kong Nguyen, Richard M Source Type: research
[ASAP] Pyrazole Ureas as Low Dose, CNS Penetrant Glucosylceramide Synthase Inhibitors for the Treatment of Parkinson ’s Disease
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00441 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 12, 2023 Category: Chemistry Authors: Anthony J. Roecker, Kathy M. Schirripa, H. Marie Loughran, Ling Tong, Tao Liang, Kerry L. Fillgrove, Yuhsin Kuo, Kelly Bleasby, Hannah Collier, Michael D. Altman, Melissa C. Ford, Robert E. Drolet, Mali Cosden, Sarah Jinn, Nathan G. Hatcher, Lihang Yao, M Source Type: research
[ASAP] Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00454 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 10, 2023 Category: Chemistry Authors: Esther Torrente, Valentina Fodale, Alina Ciammaichella, Federica Ferrigno, Jesus M. Ontoria, Simona Ponzi, Ilaria Rossetti, Alessio Sferrazza, Je ́rôme Amaudrut, Antonino Missineo, Simone Esposito, Simone Palombo, Martina Nibbio, Mauro Cerretani, Monic Source Type: research
[ASAP] Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00436 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 4, 2023 Category: Chemistry Authors: Jamie A. Jarusiewicz, Satoshi Yoshimura, Anand Mayasundari, Marisa Actis, Anup Aggarwal, Kevin McGowan, Lei Yang, Yong Li, Xiang Fu, Vibhor Mishra, Richard Heath, Shilpa Narina, Shondra M. Pruett-Miller, Gisele Nishiguchi, Jun J. Yang, and Zoran Rankovic Source Type: research
[ASAP] Lipase-Catalyzed Synthesis and Biological Evaluation of < italic toggle="yes" > N < /italic > ‑Picolineamides as < italic toggle="yes" > Trypanosoma cruzi < /italic > Antiproliferative Agents
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00425 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - January 3, 2023 Category: Chemistry Authors: Fabricio Freije Garci ́a, Daniel Musikant, José L. Escalona, Martín M. Edreira, and Guadalupe García Liñares Source Type: research
[ASAP] Novel PSMA-Targeting Radionuclide Peptidomimetics for Treating Prostate Cancer
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00510 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - December 23, 2022 Category: Chemistry Authors: C. S. Brian Chia Source Type: research
[ASAP] Synthesis of Novel Kidney-Type Glutaminase Allosteric Inhibitors Targeting the Critical Lys-320 Residue
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00302 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - December 22, 2022 Category: Chemistry Authors: Jun Song, Chuqiao Pan, Jinxiu Li, Ruisong Bai, Ziying Zeng, Yunying Han, Zhao Chen, Wei Hou, Yong Li, and Benfang Helen Ruan Source Type: research
[ASAP] Using Imidazo[2,1 ‑ < italic toggle="yes" > b < /italic > ][1,3,4]thiadiazol Skeleton to Design and Synthesize Novel MNK Inhibitors
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.2c00442 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - December 15, 2022 Category: Chemistry Authors: Xin Jin, Tingting Qiu, Jianling Xie, Xianfeng Wei, Xuemin Wang, Rilei Yu, Christopher Proud, and Tao Jiang Source Type: research
