[ASAP] The Quest for Oral PROTAC drugs: Evaluating the Weaknesses of the Screening Pipeline
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00231 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 3, 2023 Category: Chemistry Authors: Giulia Apprato, Giuseppe Ermondi, and Giulia Caron Source Type: research
[ASAP] Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL ‑1
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00141 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - July 3, 2023 Category: Chemistry Authors: Samue ̈l Demin, Aldo Peschiulli, Adriana I. Velter, Ann Vos, Benoît De Boeck, Bradley Miller, Frederik J. R. Rombouts, Tristan Reuillon, William Lento, Maria Dominguez Blanco, Matthieu Jouffroy, Helena Steyvers, Mariette Bekkers, Cristina Altrocchi, Be Source Type: research
[ASAP] The Hitchhiker ’s Guide to Deep Learning Driven Generative Chemistry
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00041 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 30, 2023 Category: Chemistry Authors: Yan Ivanenkov, Bogdan Zagribelnyy, Alex Malyshev, Sergei Evteev, Victor Terentiev, Petrina Kamya, Dmitry Bezrukov, Alex Aliper, Feng Ren, and Alex Zhavoronkov Source Type: research
[ASAP] Synthesis and Determination of Anticancer Activity of Dicobalt Hexacarbonyl 2 ′-Deoxy-5-alkynylfuropyrimidines
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00152 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 29, 2023 Category: Chemistry Authors: Renata Kaczmarek, Ewa Radzikowska-Cieciura, Karolina Kro ́lewska-Golińska, Rafa Dolot, Kraig A. Wheeler, Ferman A. Chavez, and Roman Dembinski Source Type: research
[ASAP] < italic toggle="yes" > Mycobacterium tuberculosis < /italic > PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00162 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 26, 2023 Category: Chemistry Authors: Samantha Ottavi, Kelin Li, Jackson G. Cacioppo, Andrew J. Perkowski, Remya Ramesh, Ben S. Gold, Yan Ling, Julia Roberts, Amrita Singh, David Zhang, John Mosior, Laurent Goullieux, Christine Roubert, Eric Bacque ́, James C. Sacchettini, Carl F. Nathan, an Source Type: research
[ASAP] Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00224 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 23, 2023 Category: Chemistry Authors: Alessandro Farinato, Maria Maddalena Cavalluzzi, Concetta Altamura, Carmen Campanale, Paola Laghetti, Ilaria Saltarella, Pietro Delre, Arthur Barbault, Nancy Tarantino, Gualtiero Milani, Natalie Paola Rotondo, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Source Type: research
[ASAP] Discovery of a Series of Indane-Containing NBTIs with Activity against Multidrug-Resistant Gram-Negative Pathogens
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00187 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 22, 2023 Category: Chemistry Authors: John G. Cumming, Lukas Kreis, Holger Ku ̈hne, Roger Wermuth, Maarten Vercruysse, Christian Kramer, Markus G. Rudolph, and Zhiheng Xu Source Type: research
[ASAP] Novel Lactams as CBL ‑B Inhibitors for Treating Cancer
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00247 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 21, 2023 Category: Chemistry Authors: Ram W. Sabnis Source Type: research
[ASAP] Novel Diaminopyrimidine Carboxamides as HPK1 Inhibitors for Treating Cancer
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00249 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 21, 2023 Category: Chemistry Authors: Ram W. Sabnis Source Type: research
[ASAP] Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00163 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 21, 2023 Category: Chemistry Authors: Matthew G. LaPorte ◇, Celeste Alverez, Alexander Chatterley◇, Marina Kovaliov◇, Evan J. Carder◇, Michael J. Houghton◇, Chaemin Lim◇, Eric R. Miller◇, Lalith P. Samankumara◇, Mary Liang, Kaylan Kerrigan◇, Zhizhou Yue◇, Shan Li, Francesc Source Type: research
[ASAP] Parkinson ’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00070 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 15, 2023 Category: Chemistry Authors: Youcef Mehellou Source Type: research
[ASAP] Discovery of [ < sup > 11 < /sup > C]MK-8056: A Selective PET Imaging Agent for the Study of mGluR < sub > 2 < /sub > Negative Allosteric Modulators
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00175 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 13, 2023 Category: Chemistry Authors: James J. Perkins, Paul McQuade, Christopher J. Bungard, Tracy L. Diamond, Liza T. Gantert, Anthony L. Gotter, Barbara Hanney, Ivory D. Hills, Danielle M. Hurzy, Aniket Joshi, Jonathan T. Kern, Kelly-Ann S. Schlegel, Jesse J. Manikowski, Zhaoyang Meng, Jul Source Type: research
[ASAP] Anti-infectives Developed as Racemic Drugs in the 21st Century: Norm or Exception?
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00214 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 12, 2023 Category: Chemistry Authors: Diego Gonza ́lez Cabrera, Dennis A. Smith, Gregory S. Basarab, James Duffy, Thomas Spangenberg, and Kelly Chibale Source Type: research
[ASAP] Discovery of Potent, Dual-Inhibitors of Diacylglycerol Kinases Alpha and Zeta Guided by Phenotypic Optimization
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00063 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 12, 2023 Category: Chemistry Authors: Louis Chupak, Michael Wichroski, Xiaofan Zheng, Min Ding, Scott Martin, Christopher Allard, Jianliang Shi, Robert Gentles, Nicholas A. Meanwell, Jie Fang, Daniel Tenney, John Tokarski, Carolyn Cao, and Susan Wee Source Type: research
[ASAP] Novel Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia
ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.3c00234 (Source: ACS Medicinal Chemistry Letters)
Source: ACS Medicinal Chemistry Letters - June 12, 2023 Category: Chemistry Authors: Ram W. Sabnis Source Type: research
