Correction to: Effect of Nicorandil, Diltiazem, or Isosorbide Mononitrate for Oral Antispastic Therapy After Coronary Artery Bypass Grafting Using Radial Artery Grafts —A Pilot Randomized Controlled Trial (ASRAB-Pilot): Rationale and Study Protocol
(Source: Advances in Therapy)
Source: Advances in Therapy - August 10, 2023 Category: Drugs & Pharmacology Source Type: research
Effect of Nicorandil, Diltiazem, or Isosorbide Mononitrate for Oral Antispastic Therapy After Coronary Artery Bypass Grafting Using Radial Artery Grafts —A Pilot Randomized Controlled Trial (ASRAB-Pilot): Rationale and Study Protocol
ConclusionThis pilot trial will compare the preliminary effects of nicorandil, diltiazem, and isosorbide mononitrate on angiographic and clinical outcomes in patients who have undergone RA-CABG. Recruitment began in June 2020, and the estimated primary completion date is early 2023. Results of this study will provide much needed information for design of large confirmatory trials on the effectiveness of oral antispastic medications after RA-CABG. (Source: Advances in Therapy)
Source: Advances in Therapy - July 11, 2023 Category: Drugs & Pharmacology Source Type: research
Isosorbide Mononitrate and Cilostazol in Patients With Symptomatic Cerebral Small Vessel Disease
This randomized clinical trial examines treatment outcomes with isosorbide mononitrate and cilostazol in patients with symptomatic cerebral small vessel disease. (Source: JAMA Neurology)
Source: JAMA Neurology - May 24, 2023 Category: Neurology Source Type: research
Data mining techniques for detecting signals of adverse drug reaction of cardiac therapy drugs based on Jinan adverse event reporting system database: a retrospective study
Conclusion
We identified 14 new cardiac therapy drug signals that did not appear on drug labels in China and 1 new signal that did not appear on drug labels in 3 counties. A causal link between cardiac therapy drugs and AEs should be evaluated in further studies. (Source: BMJ Open)
Source: BMJ Open - January 20, 2023 Category: General Medicine Authors: Guan, Y., Qi, Y., Zheng, L., Yang, J., Zhang, M., Zhang, Q., Ji, L. Tags: Open access, Cardiovascular medicine Source Type: research
The Influence of < em > Ixeris sonchifolia < /em > Hance Injection Combined with Isosorbide Mononitrate in Patients with Coronary Heart Disease and Diabetes
CONCLUSION: Ixeris sonchifolia Hance plus isosorbide mononitrate may offer a viable alternative in the treatment of patients with CHD and diabetes mellitus. Future trials are, however, required prior to clinical promotion.PMID:35832520 | PMC:PMC9273379 | DOI:10.1155/2022/7503380 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - July 14, 2022 Category: Complementary Medicine Authors: Li Zhang Xiaomin Qin Source Type: research
Isosorbide mononitrate for cervical ripening during labour induction: A systematic review and meta-analysis of 23 randomized controlled trials
CONCLUSION: IMN correlated with several obstetric-related maternal outcomes. IMN was not associated with adverse neonatal outcomes, but was associated with substantial drug-related maternal side effects.PMID:35803111 | DOI:10.1016/j.ejogrb.2022.06.028 (Source: Reproductive Biology)
Source: Reproductive Biology - July 8, 2022 Category: Reproduction Medicine Authors: Ahmed Abu-Zaid Majed Saeed Alshahrani Abdulrahman Al-Matary Khalid Khadawardi Najlaa Talat Miski Mohammed Abuzaid May A Alrasheed Afnan Baradwan Abdullah Salem Raghad Salem Mohamed Ismail Albadawi Mohammed Ziad Jamjoom Abdullah Ama Almubarki Nadia Ahmed A Source Type: research
Isosorbide mononitrate for cervical ripening during labour induction: a systematic review and meta-analysis of 23 randomized controlled trials
To conduct a systematic review and meta-analysis of all randomized controlled trials (RCTs) that evaluated the efficacy and safety of isosorbide mononitrate (IMN) in promoting cervical ripening during labour induction. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 1, 2022 Category: OBGYN Authors: Ahmed Abu-Zaid, Majed Saeed Alshahrani, Abdulrahman Al-Matary, Khalid Khadawardi, Najlaa Talat Miski, Mohammed Abuzaid, May A. Alrasheed, Afnan Baradwan, Abdullah Salem, Raghad Salem, Mohamed Ismail Albadawi, Mohammed Ziad Jamjoom, Abdullah AMA Almubarki, Tags: Review article Source Type: research
PD-1 Inhibitor-Induced Thyrotoxicosis Associated with Coronary Artery Spasm and Ventricular Tachycardia
Cardiovasc Toxicol. 2022 Jun 21. doi: 10.1007/s12012-022-09756-4. Online ahead of print.ABSTRACTProgrammed cell death protein 1 (PD-1) inhibitors open a new era of cancer immunotherapy, but they are associated with immune-related adverse events (irAEs) involving multiple endocrine organs of which thyroid dysfunction is the most common An uncommon condition of coronary artery spasm and ventricular tachycardia associated with thyrotoxicosis, induced by a PD-1 inhibitor, is discussed in this case. A 60-year-old male patient with a 1-week history of chest tightness and palpitation at rest was referred to us in July 2021. No ob...
Source: Cardiovascular Toxicology - June 21, 2022 Category: Cardiology Authors: Kai Guo Mantian Chen Jinxiang Li Source Type: research
PD-1 Inhibitor-Induced Thyrotoxicosis Associated with Coronary Artery Spasm and Ventricular Tachycardia
Cardiovasc Toxicol. 2022 Jun 21. doi: 10.1007/s12012-022-09756-4. Online ahead of print.ABSTRACTProgrammed cell death protein 1 (PD-1) inhibitors open a new era of cancer immunotherapy, but they are associated with immune-related adverse events (irAEs) involving multiple endocrine organs of which thyroid dysfunction is the most common An uncommon condition of coronary artery spasm and ventricular tachycardia associated with thyrotoxicosis, induced by a PD-1 inhibitor, is discussed in this case. A 60-year-old male patient with a 1-week history of chest tightness and palpitation at rest was referred to us in July 2021. No ob...
Source: Cardiovascular Toxicology - June 21, 2022 Category: Cardiology Authors: Kai Guo Mantian Chen Jinxiang Li Source Type: research
PD-1 Inhibitor-Induced Thyrotoxicosis Associated with Coronary Artery Spasm and Ventricular Tachycardia
Cardiovasc Toxicol. 2022 Jun 21. doi: 10.1007/s12012-022-09756-4. Online ahead of print.ABSTRACTProgrammed cell death protein 1 (PD-1) inhibitors open a new era of cancer immunotherapy, but they are associated with immune-related adverse events (irAEs) involving multiple endocrine organs of which thyroid dysfunction is the most common An uncommon condition of coronary artery spasm and ventricular tachycardia associated with thyrotoxicosis, induced by a PD-1 inhibitor, is discussed in this case. A 60-year-old male patient with a 1-week history of chest tightness and palpitation at rest was referred to us in July 2021. No ob...
Source: Cardiovascular Toxicology - June 21, 2022 Category: Cardiology Authors: Kai Guo Mantian Chen Jinxiang Li Source Type: research
Preclusion of methemoglobinemia caused by nitrate drugs in diabetics and nondiabetics: Possible role of Vitamin C
Blood Cells Mol Dis. 2022 Jan 5;94:102643. doi: 10.1016/j.bcmd.2021.102643. Online ahead of print.ABSTRACTThe drugs containing nitrates like isosorbide dinitrate, isosorbide mononitrate and glyceryl trinitrate, etc., trigger the oxidation of hemoglobin which is manifested in the pathological disorder named methemoglobinemia. It was considered interesting to investigate the preventive roles of vitamin C towards the toxic effects of nitrate containing drugs used for the treatment of angina. The aim is to find whether these drugs need to be administered with special care to diabetic patients who are more prone to develop meth...
Source: Blood Cells, Molecules and Diseases - January 16, 2022 Category: Hematology Authors: Debashree Das Souvik Sen Santanu Bhakta Kamalika Sen Source Type: research
Preclusion of methemoglobinemia caused by nitrate drugs in diabetics and nondiabetics: Possible role of Vitamin C
Blood Cells Mol Dis. 2022 Jan 5;94:102643. doi: 10.1016/j.bcmd.2021.102643. Online ahead of print.ABSTRACTThe drugs containing nitrates like isosorbide dinitrate, isosorbide mononitrate and glyceryl trinitrate, etc., trigger the oxidation of hemoglobin which is manifested in the pathological disorder named methemoglobinemia. It was considered interesting to investigate the preventive roles of vitamin C towards the toxic effects of nitrate containing drugs used for the treatment of angina. The aim is to find whether these drugs need to be administered with special care to diabetic patients who are more prone to develop meth...
Source: Blood Cells, Molecules and Diseases - January 16, 2022 Category: Hematology Authors: Debashree Das Souvik Sen Santanu Bhakta Kamalika Sen Source Type: research
Preclusion of methemoglobinemia caused by nitrate drugs in diabetics and nondiabetics: Possible role of Vitamin C
Blood Cells Mol Dis. 2022 Jan 5;94:102643. doi: 10.1016/j.bcmd.2021.102643. Online ahead of print.ABSTRACTThe drugs containing nitrates like isosorbide dinitrate, isosorbide mononitrate and glyceryl trinitrate, etc., trigger the oxidation of hemoglobin which is manifested in the pathological disorder named methemoglobinemia. It was considered interesting to investigate the preventive roles of vitamin C towards the toxic effects of nitrate containing drugs used for the treatment of angina. The aim is to find whether these drugs need to be administered with special care to diabetic patients who are more prone to develop meth...
Source: Blood Cells, Molecules and Diseases - January 16, 2022 Category: Hematology Authors: Debashree Das Souvik Sen Santanu Bhakta Kamalika Sen Source Type: research
Effect of vaginal misoprostol plus isosorbide mononitrate on pain perception during copper intrauterine device insertion in women delivered only by elective cesarean section
To examine the analgesic effect of vaginal misoprostol plus isosorbide mononitrate (IMN) versus misoprostol alone in alleviating pain during intrauterine device (IUD) insertion in women delivered only by elective cesarean section (CS). (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2021 Category: Reproduction Medicine Authors: Ahmed M. Abbas, Ihab Elnashar, Eman Ramadan, Mohamed Abdellah Source Type: research
