The Effect of Open-Label Semaglutide on Metabolic Dysfunction-Associated Steatotic Liver Disease in People With HIV
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M23-3354. Online ahead of print.NO ABSTRACTPMID:38684100 | DOI:10.7326/M23-3354 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Jordan E Lake Douglas W Kitch Amy Kantor Raja Muthupillai Karin L Klingman Christina Vernon Pablo F Belaunzaran-Zamudio Carl J Fichtenbaum Sonya Heath Hugo Perazzo Kathleen Corey Todd T Brown Alan Landay Fred Sattler Kristine M Erlandson Source Type: research

Sodium-Glucose Cotransporter-2 Inhibitors and the Risk for Dialysis and Cardiovascular Disease in Patients With Stage 5 Chronic Kidney Disease
CONCLUSION: This emulated target trial showed that SGLT2i use was associated with a lower risk for dialysis, cardiovascular events, DKA, and AKI than no SGLT2i use in patients with T2D and stage 5 CKD.PRIMARY FUNDING SOURCE: National Health Research Institutes, Taiwan.PMID:38684099 | DOI:10.7326/M23-1874 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Fu-Shun Yen Chii-Min Hwu Jia-Sin Liu Yi-Ling Wu Keong Chong Chih-Cheng Hsu Source Type: research

Annals Video Summary - Benefits and Risks of Receiving Investigational Solid Tumor Drugs in Randomized Trials
Ann Intern Med. 2024 Apr 30:eM240739. doi: 10.7326/M24-0739. Online ahead of print.NO ABSTRACTPMID:38684098 | DOI:10.7326/M24-0739 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Source Type: research

Changes in liver and kidney function, red blood cell count and hemoglobin levels 1  day after ultrasound-guided percutaneous microwave ablation for uterine fibroids
CONCLUSION: Ultrasound-guided percutaneous microwave ablation for uterine fibroids can impose a higher detoxification load on the liver and cause thermal damage to and the destruction of RBCs within local circulation, potentially leading to AKI. Protein levels significantly decreased after UPMWA. Therefore, perioperative organ function protection measures and treatment should be actively integrated into clinical practice to improve prognosis and enhance recovery.PMID:38684224 | DOI:10.1080/02656736.2024.2338542 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 29, 2024 Category: Internal Medicine Authors: Xiao-Yu Huang Qin-Sheng Lu Shao-Ping Wu Han-Ming Huang Yong-Fa Zhang Source Type: research

The evaluation of depression and anxiety levels of mothers of patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome and familial Mediterranean fever
CONCLUSION: Depression and anxiety scores of mothers with children diagnosed with FMF and PFAPA are similar. These two diseases affect families psychosocially at similar levels. It is important to provide psychosocial support to families.PMID:38683959 | DOI:10.1080/00325481.2024.2347829 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 29, 2024 Category: Internal Medicine Authors: Elif Arslanoglu Aydin Esra Baglan İlknur Bagrul Nesibe Gokce Kocamaz Serife Tuncez Mehmet Bulbul Semanur Ozdel Source Type: research

Primary peritoneal carcinoma presented with abdominal pain in patient with kidney transplantation
Korean J Intern Med. 2024 Apr 29. doi: 10.3904/kjim.2023.254. Online ahead of print.NO ABSTRACTPMID:38680009 | DOI:10.3904/kjim.2023.254 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Eunmi Jo Sang Heon Song Source Type: research

Estimated Medicare Part D Savings From Generic Drugs With a Skinny Label
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M23-3212. Online ahead of print.NO ABSTRACTPMID:38684101 | DOI:10.7326/M23-3212 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Alexander C Egilman Aaron S Kesselheim Ameet Sarpatwari Benjamin N Rome Source Type: research

The Benefits and Risks of Receiving Investigational Solid Tumor Drugs in Randomized Trials : A Systematic Review and Meta-analysis
CONCLUSION: Assignment to experimental groups produces statistically significant survival gains. However, the absolute survival gain is small, and toxicity is statistically significantly greater. The findings of this review provide reassuring evidence that patients are not meaningfully disadvantaged by assignment to comparator groups.PRIMARY FUNDING SOURCE: Canadian Institutes of Health Research.PMID:38684102 | DOI:10.7326/M23-2515 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Renata Iskander Hannah Moyer Dean Fergusson Sean McGrath Andrea Benedetti Jonathan Kimmelman Source Type: research

Medicare Negotiation's Drug Reformulation Problem
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M24-0138. Online ahead of print.NO ABSTRACTPMID:38684103 | DOI:10.7326/M24-0138 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Matthew Vogel Benjamin N Rome Aaron S Kesselheim William B Feldman Source Type: research

Annals Video Summary - Benefits and Risks of Receiving Investigational Solid Tumor Drugs in Randomized Trials
Ann Intern Med. 2024 Apr 30:eM240739. doi: 10.7326/M24-0739. Online ahead of print.NO ABSTRACTPMID:38684098 | DOI:10.7326/M24-0739 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Source Type: research

Sodium-Glucose Cotransporter-2 Inhibitors and the Risk for Dialysis and Cardiovascular Disease in Patients With Stage 5 Chronic Kidney Disease
CONCLUSION: This emulated target trial showed that SGLT2i use was associated with a lower risk for dialysis, cardiovascular events, DKA, and AKI than no SGLT2i use in patients with T2D and stage 5 CKD.PRIMARY FUNDING SOURCE: National Health Research Institutes, Taiwan.PMID:38684099 | DOI:10.7326/M23-1874 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Fu-Shun Yen Chii-Min Hwu Jia-Sin Liu Yi-Ling Wu Keong Chong Chih-Cheng Hsu Source Type: research

The Effect of Open-Label Semaglutide on Metabolic Dysfunction-Associated Steatotic Liver Disease in People With HIV
Ann Intern Med. 2024 Apr 30. doi: 10.7326/M23-3354. Online ahead of print.NO ABSTRACTPMID:38684100 | DOI:10.7326/M23-3354 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Jordan E Lake Douglas W Kitch Amy Kantor Raja Muthupillai Karin L Klingman Christina Vernon Pablo F Belaunzaran-Zamudio Carl J Fichtenbaum Sonya Heath Hugo Perazzo Kathleen Corey Todd T Brown Alan Landay Fred Sattler Kristine M Erlandson Source Type: research

Changes in liver and kidney function, red blood cell count and hemoglobin levels 1  day after ultrasound-guided percutaneous microwave ablation for uterine fibroids
CONCLUSION: Ultrasound-guided percutaneous microwave ablation for uterine fibroids can impose a higher detoxification load on the liver and cause thermal damage to and the destruction of RBCs within local circulation, potentially leading to AKI. Protein levels significantly decreased after UPMWA. Therefore, perioperative organ function protection measures and treatment should be actively integrated into clinical practice to improve prognosis and enhance recovery.PMID:38684224 | DOI:10.1080/02656736.2024.2338542 (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 29, 2024 Category: Internal Medicine Authors: Xiao-Yu Huang Qin-Sheng Lu Shao-Ping Wu Han-Ming Huang Yong-Fa Zhang Source Type: research

The evaluation of depression and anxiety levels of mothers of patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome and familial Mediterranean fever
CONCLUSION: Depression and anxiety scores of mothers with children diagnosed with FMF and PFAPA are similar. These two diseases affect families psychosocially at similar levels. It is important to provide psychosocial support to families.PMID:38683959 | DOI:10.1080/00325481.2024.2347829 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 29, 2024 Category: Internal Medicine Authors: Elif Arslanoglu Aydin Esra Baglan İlknur Bagrul Nesibe Gokce Kocamaz Serife Tuncez Mehmet Bulbul Semanur Ozdel Source Type: research

Early intervention is important when administering glucarpidase for methotrexate intoxication. Author's reply
Eur J Intern Med. 2024 Apr 29:S0953-6205(24)00174-2. doi: 10.1016/j.ejim.2024.04.014. Online ahead of print.NO ABSTRACTPMID:38685140 | DOI:10.1016/j.ejim.2024.04.014 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: G Miceli M Daidone F Corpora F Di Gaudio A Tuttolomondo METHOTRETOXY GROUP Source Type: research