Preventing necroptosis by scavenging ROS production alleviates heat stress-induced intestinal injury.
Conclusion: This study provides strong evidence that HS causes damage to both the small intestine and intestinal epithelial cells, scavenging ROS production can significantly alleviate such RIPK1/RIPK3-dependent necroptosis, mediating HS-induced intestinal damage both in vitro and in vivo. These findings provide a clear target for future mechanism-based therapeutic strategies for patients diagnosed with heat stroke. PMID: 32423248 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Mathematical modeling of the thermal effects of irreversible electroporation for in  vitro, in vivo, and clinical use: a systematic review.
Conclusions: Simulation results in this review show that significant mild-hyperthermic effects occur in a large part of the IRE-TR, and direct thermal ablation in comparatively small regions. Future studies should aim to optimize clinical IRE protocols, maintaining a maximum irreversible permeabilized region with minimal TA effects. PMID: 32423258 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Mammalian cell sensitivity to hyperthermia in various cell lines: a new universal and predictive description.
Conclusion: The tools offered here can be useful for designing treatments combining hyperthermia and chemotherapy targeting molecular chaperones, but also for designing personalized hyperthermic treatment by prior biochemical screening of molecular chaperones. These tools could advantageously replace the description of CEM43. PMID: 32423261 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Percutaneous radiofrequency ablation in intrahepatic cholangiocarcinoma: a retrospective single-center experience.
Conclusion: Tumor size ≥20 mm was associated with lower LTPFS, representing a potential useful threshold value. A careful evaluation of tumor burden appears as a crucial element in choosing the best therapeutic strategy in unresectable ICC. PMID: 32396398 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 14, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Immediate post-interventional contrast-enhanced computed tomography overestimates hepatic microwave ablation - an in  vivo animal study.
Conclusions: Immediate post-interventional CECT overestimated the clinically relevant zone of complete cell ablation after MWA in porcine liver in vivo. This entails the risk of incomplete tumor ablation and could lead to tumor recurrence. PMID: 32396401 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 14, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Multidisciplinary management and outcome in pancreatic cancer patients treated with high-intensity focused ultrasound.
Authors: Thudium M, Bette B, Tonguc T, Ghaei S, Conrad R, Becher MU, Mücke M, Luechters G, Strunk H, Marinova M Abstract Introduction: High-intensity focused ultrasound (HIFU) for pancreatic cancer is a growing therapeutic field which has been proven to reduce cancer pain and provide a local tumor control additionally to standard palliative care. However, less is known about the multidisciplinary and especially anesthesiological management of HIFU treatment although an interdisciplinary approach is crucial for treatment success.Material and methods: Anesthesiological and radiological records of 71 HIFU-treated...
Source: International Journal of Hyperthermia - May 14, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Acute kidney injury after nephron sparing surgery and microwave ablation: focus on incidence, survival impact and prediction.
Conclusion: AKI was an early indicator for poor overall survival in RCC patients. It can be predicted by several oncological parameters. Nomogram and Law of Total Probability can accurately predict AKI risk and SP. PMID: 32396482 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 14, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Comparison of ultrasound-guided thermal ablation and conventional thyroidectomy for benign thyroid nodules: a systematic review and meta-analysis.
This study is registered with PROSPERO (CRD42019125643).Results: Seven studies involving 1289 patients were included. The results demonstrated that the incidences of hoarseness [odds ratio (OR) 0.33, 95% confidence interval (95% CI) (0.14, 0.79)], hypothyroidism [risk difference (RD) -0.31, 95% CI (-0.34, -0.28)] and postoperative pain [OR 0.35, 95% CI (0.25, 0.49)] were lower, and the hospitalization time was shorter [standard mean difference (SMD) -4.01, 95% CI (-4.22, -3.81)], in the thermal ablation group than in the conventional thyroidectomy group, and postoperative cosmetic effects were better [relative risk (RR) ra...
Source: International Journal of Hyperthermia - May 7, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Multipotent mesenchymal stromal cells are sensitive to thermic stress - potential implications for therapeutic hyperthermia.
Conclusion: Human MSCs exhibit a thermosensitive phenotype which reduced the multipotent cells' regenerative abilities, resulting in impaired tissue regeneration after hyperthermia treatment or thermal injuries. On the other hand, tumor-associated MSCs may be efficiently targeted by hyperthermia treatment. PMID: 32369711 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 7, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Efficacy and safety of microwave ablation for cervical metastatic lymph nodes arising post resection of papillary thyroid carcinoma: a retrospective study.
Conclusion: MWA is a safe and effective novel treatment option for cervical metastatic LN that emerge post resection of PTC. PMID: 32369712 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 7, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

The value of acoustic radiation force impulse imaging in preoperative prediction for efficacy of high-Intensity focused ultrasound uterine fibroids ablation.
Authors: Zhang DL, Liu XX, Tang JQ, Wu SS, Lin N, Ding GS, Pan XL, Chen S Abstract Objective: To investigate the application value of acoustic radiation force impulse imaging in preoperative prediction for efficacy of High-Intensity Focused Ultrasound uterine fibroids ablationMethods: A prospective study was conducted on 32 women (41 fibroids) undergoing HIFU uterine fibroids ablation between January 2019 and September 2019. The virtual touch tissue quantification (VTQ) technique was used for the preoperative determination of uterine fibroids shear wave velocity (SWV). The stiffness of the preoperative uterine fibr...
Source: International Journal of Hyperthermia - May 3, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

The impact of ultrasound-guided high-intensity focused ultrasound for uterine fibroids on ovarian reserve.
Conclusion: Based on our results, we conclude that USgHIFU has no influence on ovarian reserve. PMID: 32345115 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 1, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Analysis of magnetic resonance signal intensity changes in the sacrococcygeal region of patients with uterine fibroids treated with high intensity focused ultrasound ablation.
Conclusions: The location of the uterus, the distance between the dorsal side of the fibroids to the sacrum, and ablation efficiency have a significant relationship with the MR signal intensity changes. The size of the uterus and the degree of enhancement are related to the locations of MR signal changes. PMID: 32347132 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 1, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

A feasibility and safety study of computed tomography-guided percutaneous microwave ablation: a novel therapy for multiple synchronous ground-glass opacities of the lung.
Conclusion: CT-guided percutaneous MWA for the treatment of multiple synchronous lung GGOs is feasible, safe, and efficacious over short-term follow-up. It may also be employed as an alternative approach for nonsurgical candidates. A longer follow-up is warranted to evaluate the oncologic outcomes. PMID: 32347133 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - May 1, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Efficacy and safety of ultrasonography-guided radiofrequency ablation for the treatment of T1bN0M0 papillary thyroid carcinoma: a retrospective study.
Authors: Xiao J, Zhang M, Zhang Y, Yan L, Lan Y, Zhu Y, Zhang Y, Lin L, Tang J, Luo Y Abstract Purpose: To evaluate the efficacy and safety of ultrasonography (US)-guided radiofrequency ablation (RFA) for treating low-risk T1bN0M0 papillary thyroid cancer (PTC).Methods: This retrospective study was approved by the ethics committee of the Chinese People's Liberation Army General Hospital (S2019-211-01). Sixty-six patients with T1bN0M0 PTC (14 men and 52 women with a mean age of 41.0 ± 9.2 years [range, 21-61 years]), who were not eligible for or refused surgery, were included in ou...
Source: International Journal of Hyperthermia - April 30, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

wIRA: hyperthermia as a treatment option for intracellular bacteria, with special focus on Chlamydiae and Mycobacteria.
In conclusion, wIRA is a promising tool for reducing infectious burden due to intracellular bacteria such as M. ulcerans and C. trachomatis. PMID: 32319834 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 24, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Microwave ablation versus sorafenib for intermediate-Stage Hepatocellular carcinoma with transcatheter arterial chemoembolization refractoriness: a propensity score matching analysis.
Conclusions: MWA was superior to sorafenib in improving survival for intermediate-stage hepatocellular carcinoma (HCC) patients with tumor size ≤7 cm and tumor number ≤5 after TACE failure.Key PointsCompared with sorafenib, microwave ablation may be a more reasonable alternative treatment for intermediate-stage hepatocellular carcinoma (HCC) patients with tumor size ≤7 cm and tumor number ≤5 after TACE refractoriness.The treatment (MWA vs sorafenib) and the age of patients were the independent prognostic factors of OS and PFS. PMID: 32323585 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 24, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

US-guided laser treatment of parathyroid adenomas.
Authors: Appelbaum L, Goldberg SN, Ierace T, Mauri G, Solbiati L Abstract Objective: To determine the clinical efficacy of laser ablation for the tredatment of primary hyperparathyroidism (pHPT).Materials and methods: Twelve patients with pHPT were treated with laser ablation. Energy was administered by means of 1.5 m optical fibers percutaneously placed into the target via 21 G needles. A laser ablation unit (EchoLaser X4, Esaote) applied 3 W power for 400-600 s/fiber/insertion to a total 3600-9000 Joules of energy. Patient serum parathyroid hormone (PTH) and calcium levels were checked...
Source: International Journal of Hyperthermia - April 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Mathematical modeling of mass and energy transport for thermoembolization.
Conclusion: These efforts present a first step toward formalizing a mathematical model for thermoembolization and are promising for providing insight for delivery protocol optimization. While our approach captured the observed experimental temperature measurements, larger-scale experimental validation is needed to prioritize additional model complexity and fidelity. PMID: 32308071 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

MR-guided microwave ablation in hepatic malignancies: clinical experiences from 50 procedures.
Conclusion: MR-guided MWA allows for safe and successful treatment of hepatic malignancies with a high technique efficacy however with relatively long procedure durations. PMID: 32286087 [PubMed - as supplied by publisher] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 15, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Clinical efficacy and mechanism for focused ultrasound (FUS) in the management of cervical intraepithelial neoplasia 1 (CIN1).
This study was aimed at investigating the clinical efficacy and studying the possible mechanism of FUS applications to treat cervical intraepithelial neoplasia 1 (CIN1).Methods: This was a prospective clinical study, in which 30 patients with CIN1 (28/30 of the patients were HPV positive) were enrolled and treated with FUS therapy by gynecologist. All patients were followed up for 3 months after FUS therapy. Telephone interviews, PAP smear, colposcopic examinations, cervical biopsies and HPVDNA tests were performed to assess the safety and effectiveness of FUS therapy for HPV-positive CIN1. The expression of p16, Ki...
Source: International Journal of Hyperthermia - April 11, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

For HIPEC, synergistic effects of hyperthermia and doxorubicin are optimal when simultaneously combined.
Authors: Sharma A, Rudek MA, Korangath P, Bunz F, Ivkov R PMID: 32270728 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 11, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Stereotactic radiofrequency thermocoagulation application in the anterior limbs of patients' internal capsules in treating intractable tic disorders.
Authors: Li YH, Zhao K, Wang MQ, Wang J, Gao BL Abstract Purpose: To investigate the effect of applying stereotactic radiofrequency thermocoagulation in the anterior limbs of patients' internal capsules in treating intractable tic disorders.Materials and methods: Patients diagnosed with intractable tic disorders were prospectively enrolled and treated using stereotactic radiofrequency thermocoagulation in the anterior limbs of the internal capsules. Periprocedural complications, effects, and follow-up outcomes were then analyzed.Results: Fifty patients were enrolled, including 38 with Tourette syndrome and 12 with ...
Source: International Journal of Hyperthermia - April 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Identifying predictive factors for efficacy in high intensity focused ultrasound (HIFU) ablation of benign thyroid nodules - a retrospective analysis.
Conclusions: Percentage change in serum FT4 on post-treatment Day-4 was an independent blood parameter for the subsequent nodule shrinkage at 12 months. This finding could potentially facilitate the decision for earlier retreatment of treated nodules. PMID: 32253953 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Efficacy and safety of microwave ablation treatment for secondary hyperparathyroidism: systematic review and meta-analysis.
Authors: Cao XJ, Zhao ZL, Wei Y, Peng LL, Li Y, Yu MA Abstract Purpose: The present systematic review and meta-analysis was designed to evaluate the efficacy and safety of microwave ablation (MWA) treatment for secondary hyperparathyroidism (SHPT).Materials and methods: The study authors systematically searched the Web of Science, Cochrane Library, PubMed, Embase and Ovid databases for studies published in English prior to 7October 2019. All studies included in the meta-analysis measured levels of parathyroid hormone (PTH), calcium and phosphorus, and included data related to complications following MWA treatment f...
Source: International Journal of Hyperthermia - April 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Expression of Concern.
Authors: PMID: 32255365 [PubMed - as supplied by publisher] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - April 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Thermally sensitive fluorescence imaging system for radiofrequency ablation guidance.
Authors: Guo X, Gai Y, Du F, Wang Q, Sun L, Ding X, Zeng D, Wu Z Abstract Radiofrequency ablation (RFA) has been clinically used as a minimally invasive procedure for the treatment of many solid tumors. However, the current imaging techniques have some shortages in RFA guidance, especially for the assessment of the margin of ablation. Herein, we developed a novel optical imaging platform to guide RFA utilizing fluorescence resonance energy transfer from a thermally sensitive fluorescent protein conjugated to a near-infrared fluorescent dye. Additionally, attaching receptor-targeting ligands further equipped the sys...
Source: International Journal of Hyperthermia - April 3, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

A comparison of reproductive outcomes of patients with adenomyosis and infertility treated with High-Intensity focused ultrasound and laparoscopic excision.
Conclusion: HIFU showed a safe and effective profile as a therapeutic management option for patients with adenomyosis. In comparison with LE, HIFU treatment achieved better postoperative reproductive outcomes. HIFU treatment should be encouraged and implemented in clinical practice. PMID: 32208771 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 28, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Hyperthermic intraperitoneal chemotherapy enhances blood coagulation perioperatively evaluated by thromboelastography: a pilot study.
This study assessed the impact of CRS and HIPEC on TEG values.Methods: TEG parameters reaction time (R), kinetics time (K), angle (α), maximum amplitude (MA), and lysis percent at 60 min (LY60) were determined preoperatively, and at the end of CRS, during HIPEC, and at the end of the operation using blood samples from 15 HIPEC patients. Platelets, P-TT, and aPTT were also determined before and after CRS.Results: A total of 75 samples were analyzed. During CRS, there was a significant reduction in the mean MA (3.06 mm, p = 0.001). The mean P-TT declined by 32% (p 
Source: International Journal of Hyperthermia - March 28, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Response by Li et al., to inconsistent results between the two studies comparing microwave ablation versus surgery for papillary thyroid microcarcinoma.
Authors: Li J, Li T, Qian L PMID: 32208779 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 28, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Development and characterization of a tissue mimicking psyllium husk gelatin phantom for ultrasound and magnetic resonance imaging.
Conclusions: The presented dual-use tissue-mimicking phantom is easy to manufacture and can be used to compare and evaluate US-guided and MR-guided HIFU imaging protocols. PMID: 32204632 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 25, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

MRI patterns indicate treatment success and tumor relapse following radiofrequency ablation of osteoblastoma.
Conclusion: A target-like appearance of OB in early follow-up MRI examination indicates treatment success. PNE and PBME typically reduce over time and can lead to FNC in successfully treated patients. CNE recurrence, PNE and extensive PBME are signs of relapse. PMID: 32188300 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Inconsistent results between the two studies comparing microwave ablation and surgery for papillary thyroid microcarcinoma.
Authors: Shen K, Wang H, Xie Y, Zhu J, Zhu C, Ren A PMID: 32188305 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Analysis of the effects of mEHT on the treatment-related toxicity and quality of life of HIV-positive cervical cancer patients.
Conclusion: mEHT did not cause unexpected CRT-related toxicities and is a safe treatment modality for HIV-positive patients, with minor limitations regarding body weight, even in a low-resource setting. PMID: 32180481 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 19, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Computed tomography-guided percutaneous microwave ablation with artificial ascites for problematic hepatocellular tumors.
Conclusion: CT-guided percutaneous microwave ablation with artificial ascites is a feasible, safe and effective choice for treating problematic hepatocellular tumors, avoiding potential thermal damage to the adjacent high-risk organs. PMID: 32157926 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 12, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Time interval after heat stress plays an important role in the combination therapy of hyperthermia and cancer chemotherapy agents.
Authors: Chen H, Ma G, Wang X, Zhou W, Wang S PMID: 32157930 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 12, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Efficacy and safety of US-guided thermal ablation for primary hyperparathyroidism: a systematic review and meta-analysis.
Authors: Ye J, Huang W, Huang G, Qiu Y, Peng W, Lan N, Xie X, Liu B Abstract Purpose: To summarize the published literature on thermal ablation for primary hyperparathyroidism (PHPT) and to evaluate the effectiveness and safety of thermal ablation as a novel treatment strategy.Materials and methods: Two authors carried out the literature search using four databases independently, including PubMed, Embase, Cochrane, and Web of Science. The meta-analysis included prospective and retrospective data that compared post-ablative outcomes to pre-ablative values. The primary outcomes were parathyroid hormone (PTH), serum c...
Source: International Journal of Hyperthermia - March 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Efficacy and safety assessment of an ultrasound-based thermal treatment of varicose veins in a sheep model.
Conclusion: These results support strongly the effectiveness and safety of HIFU for ablating non-invasively veins. PMID: 32133898 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 7, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Resting-state brain activity predicts selective attention deficits during hyperthermia exposure.
Conclusions: These findings suggested that altered resting-state brain activity within the attention networks might provide potential neural basis of the selective deficits for different cognitive-demand attention tasks under hyperthermia. PMID: 32126849 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - March 5, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Percutaneous ultrasound-guided 'three-step' radiofrequency ablation for giant hepatic hemangioma (5-15  cm): a safe and effective new technique.
Percutaneous ultrasound-guided 'three-step' radiofrequency ablation for giant hepatic hemangioma (5-15 cm): a safe and effective new technique. Int J Hyperthermia. 2020;37(1):212-219 Authors: Qu C, Liu H, Li XQ, Feng K, Ma K Abstract Purpose: To evaluate the safety and efficacy of percutaneous ultrasound-guided 'three-step' radiofrequency ablation (RFA) for the treatment of giant hepatic hemangioma.Materials and methods: Patients with giant hepatic hemangioma who underwent percutaneous ultrasound-guided 'three-step' RFA (n = 52) and conventional RFA (n = 54) at our ce...
Source: International Journal of Hyperthermia - March 1, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Use of intra-procedural fusion imaging combining contrast-enhanced ultrasound using a perflubutane-based contrast agent and auto sweep three-dimensional ultrasound for guiding radiofrequency ablation and evaluating its efficacy in patients with hepatocellular carcinoma.
Conclusion: Intraprocedural fusion imaging combining CEUS and auto sweep three-dimensional US appears to be a useful modality for RFA guidance and evaluation of therapeutic efficacy of RFA in patients with HCC. PMID: 32070164 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 21, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Percutaneous radiofrequency ablation for small hepatocellular carcinoma in hepatic dome under MR-guidance: clinical safety and efficacy.
Conclusion: Planning, targeting, and controlling of RFA were well supported by MRI with acceptable time. MRI-guided RFA for small HCCs in the hepatic dome is safe and effective with fewer RF sessions. PMID: 32066293 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 20, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Cardiovascular reactions for whole-body thermal therapy with a hot pack and Waon therapy.
Authors: Kominami K, Noda K, Takahashi N, Izumi T, Yonezawa K Abstract Background: Waon therapy (WT) is the predominant thermal therapy for chronic heart failure in Japan, involving use of a far-infrared dry sauna. As sauna therapy requires certain equipment not readily available in hospitals, we tested the use of whole-body hot pack thermal therapy (HPTT). We compared the magnitude of skin vasodilation post-HPTT with that post-WT.Methods: We recruited 19 healthy men (age [mean ± S.D.]: 26.8 ± 4.6 years) and employed a simple randomized crossover design. The HPTT req...
Source: International Journal of Hyperthermia - February 14, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Solid benign thyroid nodules ( > 10  ml): a retrospective study on the efficacy and safety of sonographically guided ethanol ablation combined with radiofrequency ablation.
Solid benign thyroid nodules (>10 ml): a retrospective study on the efficacy and safety of sonographically guided ethanol ablation combined with radiofrequency ablation. Int J Hyperthermia. 2020;37(1):157-167 Authors: Zhu Y, Zhang M, Jin Z, Tian X, Zhang Y, Xie F, Song Q, Yan L, Jiang B, Tang J, Luo Y Abstract Background: Image-guided radiofrequency ablation (RFA) of large solid benign thyroid nodules (BTNs) usually require a high amount of energy. Injection of ethanol into a benign thyroid nodule before RFA can lower the procedural time and patient discomfort.Objective: To investigate the ef...
Source: International Journal of Hyperthermia - February 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Comparison between microwave ablation and radiofrequency ablation for treating symptomatic uterine adenomyosis.
Conclusions: The safety and effectiveness of PMWA and USgRFA in the treatment of uterine adenomyosis were similar; however, the mean ablation time of PMWA was shorter than that of USgRFA. PMID: 32024402 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma: a retrospective analysis of 198 patients.
Conclusions: US-guided RFA is safe and effective for PTMC, with a good oncological outcome and VRR. Further randomized controlled prospective trials are still needed to compare the value of RFA and surgery. PMID: 32026736 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

In memory of Dr. Claudio Maurizio Pacella: a pioneer in clinical applications of image-guided laser ablation.
Authors: Mauri G, Gambelunghe G PMID: 32031426 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - February 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

MRI evaluation of endopelvic fascial swelling and analysis of influencing factors in patients with uterine fibroids after high-intensity focused ultrasound ablation.
Authors: Zhang YJ, Xiao ZB, Lv FR, Sheng B, Li J, Zheng YN, Lv FJ, Chen JY Abstract Purpose: To evaluate endopelvic fascial swelling in patients with uterine fibroids after high-intensity focused ultrasound (HIFU) ablation on magnetic resonance imaging (MRI) and investigate the factors that influence endopelvic fascial swelling.Methods: MRI and clinical data from 188 patients with uterine fibroids who were treated with HIFU were analyzed retrospectively. The patients were divided into a fascial swelling group and a non-swelling group, and the degree of swelling was graded. Fascial swelling was set as the dependent ...
Source: International Journal of Hyperthermia - February 8, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

PIPAC versus HIPEC: cisplatin spatial distribution and diffusion in a swine model.
Authors: Davigo A, Passot G, Vassal O, Bost M, Tavernier C, Decullier E, Bakrin N, Alyami M, Bonnet JM, Louzier V, Paquet C, Allaouchiche B, Glehen O, Kepenekian V Abstract Purpose: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach for delivering intraperitoneal chemotherapy and offers perspective in the treatment of peritoneal carcinomatosis. Concept is based on a 12 mmHg capnoperitoneum loaded with drug changed in microdoplets. It was postulated to guarantee a more homogeneous drug distribution and tissular uptake than hyperthermic intraperitoneal chemotherapy (HIPEC). The aim of...
Source: International Journal of Hyperthermia - February 1, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

Synergy between induction heating, antibiotics, and N-acetylcysteine eradicates Staphylococcus aureus from biofilm.
Conclusion: Induction heating of titanium alloy coupons is effective for the reduction of bacterial load in vitro in S. aureus biofilms. Induction heating and cocktails of antibiotics and NAC have a synergistic effect that results in the total eradication of the biofilm at 60 °C and higher for clinically relevant concentrations of vancomycin, rifampicin and NAC. PMID: 31986930 [PubMed - in process] (Source: International Journal of Hyperthermia)
Source: International Journal of Hyperthermia - January 29, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research