Sunday Poem
SquishedThe stink bugs had invaded the kitchenWith summer in flightFlitting around like they do,Whacking up against walls and windows.The frosted bowl of the ceiling lightIs now an urn of upturned insect silhouettesYou kill them with a satisfying crunchUnder your shoe,Or flicked with your nail,Pressed between layers of junk mail,Like an old catalog from J Crew.The boy watching asked:Could I get squished?We paused, seekingClarification in our stunned silence.Like that bug?Well ….maybe a wrecking ball….Or a toppling wall.An unfortunate end to a car chase.My mind raced.Yes. Yes you could, I thought.But you won ’t b...
Source: Buckeye Surgeon - October 15, 2017 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs

Fight Aging! Newsletter, October 9th 2017
In this study, we investigated the Hippo pathway, which is known from my lab's previous studies to prevent adult heart muscle cell proliferation and regeneration. When patients are in heart failure there is an increase in the activity of the Hippo pathway. This led us to think that if we could turn Hippo off, then we might be able to induce improvement in heart function." "We designed a mouse model to mimic the human condition of advanced heart failure. Once we reproduced a severe stage of injury in the mouse heart, we inhibited the Hippo pathway. After six weeks we observed that the injured hearts had recovered the...
Source: Fight Aging! - October 8, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Can Aging be Slowed by Shutting Off the Inflammatory Signaling of Senescent Cells?
Today I'll point out an interesting paper in which researchers sabotage the ability of senescent cells to generate inflammation. Senescent cells are one of the root causes of aging. They are created constantly in all tissues, a normal part of the operation of cellular metabolism, but near all are destroyed shortly thereafter. Those that linger cause ever greater disruption and failure in tissues and organs because they secrete a variety of signals known as the senescence-associated secretory phenotype (SASP), useful in the short term and when localized, but outright destructive over the long term or in great volume. One of...
Source: Fight Aging! - October 5, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

3 Things You Need to Stop Doing to Get Started
“It is never too late to be what you might have been.” George Eliot Getting started with doing what you deep down want to do in life can be hard. No matter if what you want is to start exercising, create your own business on the side, write a book, improve your relationship with yourself, see other parts of the world or something entirely else. But often we make getting started a lot harder than it needs to be by standing in our own way. So in today’s article I’d like to share 3 things you need to stop doing to step out of your own way and make it so much easier to actually get started instead of just keep dreamin...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - September 6, 2017 Category: Consumer Health News Authors: Henrik Edberg Tags: Personal Development Productivity Success Source Type: blogs

Bifurcation snakes : Which side its going to sting ?
If human coronary artery is comparable to live wire , attempting  bifurcation (BFL) stenting is akin to tame a live snake .True BFL  (with Medina 1, 1, 1)  being the most complex of all .The fact is ,we have atleast a dozen strategies for BFL with varying loads of metal abutting the ostia ,side branch and carina.This  would essentially Imply we are still struggling with these lesions . While current science tends to vouch PCI* for most  BFLs . . . wisdom  might whisper CABG in atleast some of us ! Who should do complex PCI ? Obviously,  not every interventional cardiologist can. Confidence is one thing , but , f...
Source: Dr.S.Venkatesan MD - September 4, 2017 Category: Cardiology Authors: dr s venkatesan Tags: bifurcation pci Cardiology -Interventional -PCI Cardiology -unresolved questions Tips and tricks in cath lab bbc 2 study bifurcation lesion dapt after bifurcation stenting european bifurcation club Proximal optimisation pot single vs dou Source Type: blogs

TWiV 456: Be careful of canons
Brianne joins the TWiVMasters to explain how mutations in genes encoding RNA polymerase III predispose children to severe varicella, and detection of an RNA virus by a DNA sensor.   Click arrow to play Download TWiV 456 (75 MB .mp3, 124 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv. (Source: virology blog)
Source: virology blog - August 27, 2017 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology 5'-triphosphate cGAMP cGAS dengue virus DNA sensor inborn error innate immunity mitochondria RNA polymerase III STING varicella varicella-zoster virus viral viruses VZV Source Type: blogs

Is bee venom a good anti-aging ingredient? Episode 163
Is bee venom a good anti-aging ingredient? Monika asks…Korean Bee Venom essence but it does seem to work. My question is the bee venom really magic or is there something else that removes the spots? RS: Thanks Monika…this gives me the perfect excuse time to remind listeners to go back to Episode 105 and listen to the story about how Perry got stung in the eye by a bee. If nothing else, just go the webpage and check out the picture of his face. It’s horrific. I’m not kidding. But let’s put my personal revulsion aside and try to figure out why this product seemed to work on Monika’s acne. PR: We found a study pub...
Source: thebeautybrains.com - August 24, 2017 Category: Consumer Health News Authors: Randy Schueller Tags: Podcast Source Type: blogs

Home remedies: stung by a bee
Generally, bee stings are just annoying, plus home treatment is all that’s necessary to relieve the pain of bee stings. In case you’re allergic to bee stings or you get stung numerous periods, you may have a more-serious reaction that needs emergency treatment. Related Posts:How Can I Keep My Ibs Under Control?How Does Extreme Period Pain Caused By Endometriosis Differ…Treatment for IBS With Severe ConstipationNew IBS treatment shows possible in Phase 2 researchThe gene-sequence swap using CRISPR in order to cure…The post Home remedies: stung by a bee appeared first on My Irritable Bowel Syndrome ...
Source: My Irritable Bowel Syndrome Story - August 11, 2017 Category: Gastroenterology Authors: Ken Tags: IBS News Source Type: blogs

Fight Aging! Newsletter, August 7th 2017
Discussions of radical life extension, technological acceleration, and artificial general intelligence were far more fringe concerns back then than is now the case, but this growth in awareness isn't a coincidence. Visions slowly become reality because people work to make that happen. Technological progress is not accidental: it is led by our desires. I should say that de Magalhães is here generous in not passing judgement on the value (or lack thereof) of most of the various ventures and classes of approach he surveys. But some approaches are definitely better than others, and to my eyes one the principal challeng...
Source: Fight Aging! - August 6, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Linking the Bad Behavior of Senescent Cells with Innate Immune Mechanisms
Senescent cells accumulate in tissues with age, and while they make up a comparatively small fraction of all cells even in late life, they nonetheless cause great harm. These cells actively secrete a potent mix of signals, the senescence-associated secretory phenotype (SASP), that spurs chronic inflammation, degrades extracellular matrix structures, promotes fibrosis, disarrays regenerative processes, and generally changes the behavior of nearby normal cells for the worse. This materially contributes to age-related degeneration and disease. Recently, researchers have linked regulation of the SASP with mechanisms related to...
Source: Fight Aging! - August 1, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Sweetest Sound
“I am going to to do something I am passionate about,” I vowed. Fresh off college graduation, I radiated a healthy idealism. From politics to policy to mental health, I was ready to saber rattle the status quo into submission.   Six months later, I sat in a sterile office in a nondescript DC office analyzing legal psychobabble. From the crackling paint to the linoleum tiles, the office could have doubled as a psych ward. And as I listened my desultory colleagues groan in agony, maybe it was. As I walked around the office in a sullen stupor, I looked at my miserable colleagues and shook my head in disbelief. What the ...
Source: World of Psychology - July 31, 2017 Category: Psychiatry & Psychology Authors: Matthew Loeb Tags: College Industrial and Workplace Personal Students Success & Achievement Artistic Creation Calling Career Change College Grads Employment identity Passion personal quest self-compassion Source Type: blogs

Sessions' Civil Forfeiture Memo: It's Not Just the Money
Yesterday, Attorney General Jeff Sessions reanimated the suspended Department of Justice program that allows local police tocircumvent their own state laws to profit from seizing property from individuals who have not been charged, much less convicted, of a crime. Over atDemocracy: A Journal of Ideas, I wrote that this may have the unintended consequence of increasing racial profiling on American roads:Virtually  everywhere police stops are counted and measured demographically, black and/or Hispanic drivers are over-represented in those pulled over and subsequently searched for contraband. The  vast majority of searc...
Source: Cato-at-liberty - July 20, 2017 Category: American Health Authors: Jonathan Blanks Source Type: blogs

Heritage Report Shows Refugees Are Not a Major Threat
ConclusionTheHeritage Backgrounder makes a valuable and interesting contribution to the debate over the future of the American refugee program. As a side effect, it shows just how small and manageable the refugee terrorist threat is. (Source: Cato-at-liberty)
Source: Cato-at-liberty - July 13, 2017 Category: American Health Authors: David Bier, Alex Nowrasteh Source Type: blogs

Men, Mosquitos, Sex & Zika
I often hear from readers with questions about pregnancy and Zika. This series of questions from a dad explores several issues important to couples when they consider sex in a post Zika world. Q: I just returned from a trip to a tropical location. There are confirmed cases of Zika in the area and there were definitely mosquitos where I was staying. Sadly, I got a few bites – nothing crazy, but I did get a few. The CDC recommendation is to avoid sex or use condoms for six months post traveling in a Zika zone. My wife and I are not trying to have another child right now, but my wife is not on any form of birth control. W...
Source: Conversations with Dr Greene - July 10, 2017 Category: Child Development Authors: Dr. Alan Greene Tags: Dr. Greene's Blog Birth Defects Insect Bites & Stings Sex Source Type: blogs