Mitochondrial Mechanisms Link Oxidative Stress and Chronic Inflammation
Aging is characterized by rising levels of oxidative stress, the presence of oxidative molecules and the damage they cause to molecular machinery in cells, and rising levels of chronic inflammation, an inappropriate and harmful overactivation of the immune system. It is noted that these two aspects of aging and age-related disease appear to go hand in hand, when one is elevated, so is the other. Why is this the case? The obvious place to start any such investigation is the mitochondrion. Every cell is populated by hundreds of mitochondria, responsible for packaging chemical energy store molecules in a process that p...
Source: Fight Aging! - August 27, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How to Keep From Repeating Mistakes
“Each life is made up of mistakes and learning, waiting and growing, practicing patience and being persistent.” – Billy Graham How many times have you made a mistake and instantly remember you’ve made it before? Most people have this experience and recognize it when it becomes a pattern. If they fail to see the similarities between the current mistake and a past or previous one, however, they’re likely destined to repeat it multiple times. It doesn’t have to be this way. You can profit from mistakes — particularly ones that recur frequently — if you pay heed to how to keep from repeating mistakes. W...
Source: World of Psychology - August 22, 2018 Category: Psychiatry & Psychology Authors: Suzanne Kane Tags: Motivation and Inspiration Self-Help Source Type: blogs

3/27/18: How the End Began
This is one of the most difficult times for me possibly in my life? How do you judge that to know for sure though, when you cannot remember how you felt exactly at certain times that you know were hard times? Is it how I am able to cope with a situation that makes it one of the most difficult times, or is it the actual event?The actual event is now. The ability to cope would have been in August 2001 when I checked myself into the psychiatric ward, but that was chemical, I guess? Starting off on a positive...I have been going through a divorce since August 2017. Although I did not ask for it no...
Source: bipolar.and.me - August 8, 2018 Category: Psychiatry Source Type: blogs

How to Forgive a Friend Who Wronged You – And Why It’s So Important
“We may not know how to forgive, and we may not want to forgive; but the very fact we say we want to forgive begins the healing process.” – Louise Hay I’ve never been one to hold a grudge. This is not to say, however, that I haven’t been deeply wronged by a friend whom I trusted implicitly, unconditionally and without hesitation. Over the years others have asked me how to deal with the aching hurt of knowing your best friend betrayed you, what specifically to do and why it matters to do anything at all. I’ll share here the same advice I gave then and today to anyone who needs it. The key takeaway is you act to ...
Source: World of Psychology - August 8, 2018 Category: Psychiatry & Psychology Authors: Suzanne Kane Tags: Ethics & Morality Family Friends General Self-Help Source Type: blogs

Grief as a Hole in the Heart
Today, I was speaking with a friend/colleague who has been a long time addictions specialist, thanatologist and grief counselor. Dr. Yvonne Kaye is an outspoken advocate for those who are living with loss. One of her specialities is working with bereaved parents, regardless of the age of the child or the reason for their death. She has been in the trenches with them for decades and never ceases to be amazed by their resilience in the face of what is considered to be “out of the natural order of things.” Compassionate Friends is one of the organizations with which she is involved and to which she refers family m...
Source: World of Psychology - July 29, 2018 Category: Psychiatry & Psychology Authors: Edie Weinstein, MSW, LSW Tags: Books Grief and Loss Inspiration & Hope Interview Bereavement grieving Source Type: blogs

Arresting the Disease vs. Punishing the Addict
Our nation’s police are on the front lines of witnessing the consequences of substance abuse. Arresting a socialite who is high on prescription painkillers for shoplifting, or sweeping up a tented community of homeless heroin addicts off a sidewalk — to fending off the superhuman strength of a meth addict’s rage is all part of a day on the streets for lawmen. The frequency of slapping handcuffs on substance abusers during the commission of a crime has become a daily, often times hourly occurrence in most of our cities. According to the National Association of Drug Court Professionals (NADCP), more than half of a...
Source: World of Psychology - July 23, 2018 Category: Psychiatry & Psychology Authors: Stephen Cohen Henriques, CADAC II, CASAC, M.E.d Tags: Addiction Alcoholism Criminal Justice Policy and Advocacy Recovery Substance Abuse Criminalization Harm Reduction Incarceration recidivism Source Type: blogs

LITFL Review 341
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Welcome to the 341st LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM. Readers can subscribe to LITFL review RSS or LITFL review EMAIL subscription The Most Fair Dinkum Ripper Beauts of the Week PARAMEDIC-2 epi...
Source: Life in the Fast Lane - July 22, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: LITFL review LITFL R/V Source Type: blogs

On Holiday With Health Technologies
Scorching sun, ice-cold beverages, light naps in a poolside beach bed. The time for summer vacation has finally arrived, and you cannot even think of anything else just some margaritas in the pool bar. We collected the best digital technologies for you, so you don’t have to worry about emergency situations or your health on holiday. Have a great vacation! 1) Protect your skin with wearable patches! Although we have to wait a bit until nanoparticles make their way into UV-light absorbing sunscreens and anti-aging products, health apps and wearables already line up to save your skin from looking red potatoes the next day. ...
Source: The Medical Futurist - July 19, 2018 Category: Information Technology Authors: nora Tags: Health Sensors & Trackers Patients chatbot dermatology digital health food allergy food sensor health chatbot holiday summer technology telemedicine Source Type: blogs

Vacation Romance: Are You Really Ready for a Summer Fling?
“Summer lovin’ had me a blast. Summer lovin’ happened so fast”. — lyrics from “Summer Nights” in Grease. It’s a delicious fantasy, isn’t it? — falling in love while on vacation or on the summer job at the beach. Movies like Grease and Dirty Dancing make it seem so perfect, so possible, so without consequences so, I don’t know, so, so steamy and dreamy. When people think about having a “summer romance”, they are usually thinking about a fling, not a serious relationship. By definition, a summer romance is intended to last for only the summer. Often it’s a response to being in a temporary...
Source: World of Psychology - July 15, 2018 Category: Psychiatry & Psychology Authors: Marie Hartwell-Walker, Ed.D. Tags: Communication Marriage and Divorce Men's Issues Relationships Self-Help Sexuality Women's Issues Source Type: blogs

Fight Aging! Newsletter, July 16th 2018
We presently forget 98% of everything we experience. That will go away in favor of perfect, controllable, configurable memory. Skills and knowledge will become commodities that can be purchased and installed. We will be able to feel exactly as we wish to feel at any given time. How we perceive the world will be mutable and subject to choice. How we think, the very fundamental basis of the mind, will also be mutable and subject to choice. We will merge with our machines, as Kurzweil puts it. The boundary between mind and computing device, between the individual and his or her tools, will blur. Over the course of the ...
Source: Fight Aging! - July 15, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An Unconvincing Desire for Mortality
As progress towards actual, real, working rejuvenation therapies becomes ever harder to ignore, even for those without any great familiarity with the sciences, the positions espoused by those opposed to longevity is shifting. It is apparently easy to be opposed to, outraged with, up in arms about the prospect of longer human lives when longer human lives are not an option for the near future. Just as soon as rejuvenation becomes something that isn't just for the distant future elite, the tone changes. There are still all of the old inconsistencies and virtue signals, but the firm opposition becomes a good deal less firm. ...
Source: Fight Aging! - July 13, 2018 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Coping with Criticism
Want to receive a great gift? If you can imagine a gift as an item that’s not tangible, not store bought, not gift wrapped, yet is something special that’s been given to you, then I have the gift for you. I can teach you how to hear other people’s criticism in a manner that will make you feel empowered, not attacked. So empowered, in fact, that you will have no need to become deflated, defensive, enraged, victimized or attack back. “Are you kidding?” I hear you say. “No pre-frontal lobotomy for me!” Lucky for you I never did finish the course on, “Brain Surgery for Dummies.” “Well then,” you might re...
Source: World of Psychology - June 25, 2018 Category: Psychiatry & Psychology Authors: Linda Sapadin, Ph.D Tags: Perfectionism Self-Esteem Self-Help Source Type: blogs

Life will, uh, find a way
I had a bike accident a few days ago. I got “doored.” I had just completed a 19 mile ride, my usual summer route, when I decided to finish up riding on a road near my house, parallel to the park I usually ride in. I don’t know what made me change up the route, which took me next to a whole lane of parked cars; maybe just the desire to do something a tiny bit different from the park path. The driver’s side door of the Mercedes swung out, just like that, and I yelled, “NO!” but there is no stopping the laws of physics. I felt myself moving through space, I heard the crack of my helmet, the...
Source: Susan's Blog - June 12, 2018 Category: Child Development Authors: Susan Senator Tags: Uncategorized Source Type: blogs