Large Language Model-Based Evaluation of Medical Question Answering Systems: Algorithm Development and Case Study
CONCLUSIONS: Our scalable evaluation framework enables the simulation of patient populations with different health literacy levels and helps to evaluate domain specific CAs, thus promoting their integration into clinical practice. Future research aims to extend the framework to CAs without predefined content and to apply LLMs to adapt medical information to the specific (health) literacy level of the user.PMID:38682499 | DOI:10.3233/SHTI240006 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Daniel Reichenpfader Philipp R össlhuemer Kerstin Denecke Source Type: research

Acceptance of Telepresence Robotics, Telecare and Teletherapy Among Stroke Patients, Relatives and Therapy Staff
CONCLUSION: Accepted new telecare and teletherapies can be offered with the help of telepresence robotics. This requires knowledge of and experience with the technology.PMID:38682498 | DOI:10.3233/SHTI240005 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Edda Currle Sonja Haug Source Type: research

Enhancing Dementia Risk Mitigation: Standardized Digital Monitoring in Clinical Trials and Platform Design for At-Risk Elderly Individuals
CONCLUSION: The interoperability framework was designed in a scalable way and will be regularly updated for future needs.PMID:38682497 | DOI:10.3233/SHTI240004 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Hannes Hilberger Bianca Buchgraber-Schnalzer Simone Huber Theresa Weitlaner Helena Untersteiner Carina Seerainer Sten Hanke Source Type: research

Vivifying Knee Rehabilitation: SquatEmUp, a Serious Game Utilizing the Wii Fit Balance Board
Stud Health Technol Inform. 2024 Apr 26;313:7-8. doi: 10.3233/SHTI240003.ABSTRACTKnee injuries are a common concern in orthopedic and sports medicine, often requiring extensive rehabilitation to restore function and alleviate pain. The rehabilitation process can be long and challenging, necessitating innovative approaches to engage and motivate patients effectively. Serious games have emerged as a promising tool in rehabilitation, offering an interactive and enjoyable way to perform therapeutic exercises. In this context, a new serious game that leverages the Wii Fit Balance Board as an input device supported by a keyboard...
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Ren é Baranyi Marko Zivojinovic Dominik Hoelbling Christoph Aigner Werner Hoerner Thomas Grechenig Source Type: research

Analysis of Critical Incident Reports Using Natural Language Processing
CONCLUSION: The analysis of CIRS messages using text analysis tools helped in getting insights into common sources of critical incidents in Swiss healthcare institutions. In future work, we want to study more closely the relations, for example between sentiment and topics.PMID:38682495 | DOI:10.3233/SHTI240002 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Kerstin Denecke Helmut Paula Source Type: research

Controlled Mechanical Property Gradients Within a Digital Light Processing Printed Hydrogel-Composite Osteochondral Scaffold
Ann Biomed Eng. 2024 Apr 29. doi: 10.1007/s10439-024-03516-x. Online ahead of print.ABSTRACTTissue engineered scaffolds are needed to support physiological loads and emulate the micrometer-scale strain gradients within tissues that guide cell mechanobiological responses. We designed and fabricated micro-truss structures to possess spatially varying geometry and controlled stiffness gradients. Using a custom projection microstereolithography (μSLA) system, using digital light projection (DLP), and photopolymerizable poly(ethylene glycol) diacrylate (PEGDA) hydrogel monomers, three designs with feature sizes < 200 μm we...
Source: Annals of Biomedical Engineering - April 29, 2024 Category: Biomedical Engineering Authors: Kevin N Eckstein John E Hergert Asais Camila Uzcategui Sarah A Schoonraad Stephanie J Bryant Robert R McLeod Virginia L Ferguson Source Type: research

"It has to be better, otherwise we will get stuck." A Review of Novel Directions for Mental Health Reform and Introducing Pilot Work in the Netherlands
CONCLUSION: By embracing a social trial and leveraging digital platforms, the Dutch mental health care system can overcome challenges and provide more equitable, accessible, and high-quality care to individuals.PMID:38680529 | PMC:PMC11046893 | DOI:10.2174/0117450179271206231114064736 (Source: Clinical Practice and Epidemiology in Mental Health)
Source: Clinical Practice and Epidemiology in Mental Health - April 29, 2024 Category: Psychiatry Authors: Jim van Os Floortje Scheepers Michael Milo Gijs Ockeloen Sinan Guloksuz Philippe Delespaul Source Type: research

Indonesia's healthcare landscape: embracing innovation in the new health regime
Curr Med Res Opin. 2024 Apr 29:1-8. doi: 10.1080/03007995.2024.2349732. Online ahead of print.ABSTRACTThe comment highlights the intricate health issues in Indonesia, emphasizing urban-rural gaps, healthcare financing challenges, and the government's dedication to Universal Health Coverage (UHC). The country's geographical layout amplifies the struggle of providing healthcare to rural areas, resulting in substantial health concerns like high tuberculosis rates and financial vulnerability for the impoverished. The concern raised underscores the paradox of low state healthcare spending despite high household expenditures, le...
Source: Current Medical Research and Opinion - April 29, 2024 Category: Research Authors: Ferry Fadzlul Rahman Source Type: research

< em > Aquincola agrisoli < /em > sp. nov., isolated from rhizospheric soil of eggplant and < em > in silico < /em > genome mining for the prediction of biosynthetic gene clusters
Int J Syst Evol Microbiol. 2024 Apr;74(4). doi: 10.1099/ijsem.0.006355.ABSTRACTA Gram-stain negative, aerobic, rod-shaped, motile and flagellated novel bacterial strain, designated MAHUQ-54T, was isolated from the rhizospheric soil of eggplant. The colonies were observed to be light pink coloured, smooth, spherical and 0.2-0.6 mm in diameter when grown on R2A agar medium for 2 days. MAHUQ-54T was able to grow at 15-40 °C, at pH 5.5-9.0 and in the presence of 0-0.5 % NaCl (w/v). The strain gave positive results for both catalase and oxidase tests. The strain was positive for hydrolysis of l-tyrosine, urea, Tween 20 and Twe...
Source: International Journal of Systematic and Evolutionary Microbiology - April 29, 2024 Category: Microbiology Authors: Md Amdadul Huq Md Shahedur Rahman M Mizanur Rahman Source Type: research

"It's a Very Good Second Option": Older Adults' Experience of Telehealth
CONCLUSIONS: Older adults in our sample were technologically confident and capable of performing exercise sessions delivered via telehealth. They notice benefits from this form of exercise delivery however, prefer face-to-face exercise delivery.PMID:38684218 | DOI:10.1123/jpah.2023-0176 (Source: Journal of Physical Activity and Health)
Source: Journal of Physical Activity and Health - April 29, 2024 Category: Sports Medicine Authors: Brett D Buist Ben E Kramer Kemi E Wright Peter K Edwards Alyssa M Petrofes Bonnie J Furzer Source Type: research

Foundations for the scientific use of extensive health care data in Germany-results of the Data Sharing working group of the Medical Informatics Initiative
We describe the services that are necessary to provide researchers with standardized data access. They are implemented with the Research Data Portal for Health, among others. Since the pilot phase, the processes of 385 active researchers have been used on this basis, which, as of April 2024, has resulted in 19 registered projects and 31 submitted research applications.PMID:38684526 | DOI:10.1007/s00103-024-03880-y (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - April 29, 2024 Category: International Medicine & Public Health Authors: Toralf Kirsten Philip Kleinert Marie Gebhardt Johannes Drepper Anne-Katrin Andreeff Fabian Prasser Oliver Kohlbacher Source Type: research

Rapid examination of lung tissues by nonlinear microscopy
CONCLUSIONS: This study demonstrated that nonlinear microscopy readily replicates traditional H&E staining for both lung tumors and nonneoplastic pulmonary structures. Nonlinear microscopy provides many advantages over frozen section analysis and is an optical imaging platform that has the potential to augment rapid pathologic evaluation of resected tissues in the age of digital pathology.PMID:38682548 | DOI:10.1093/ajcp/aqae046 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 29, 2024 Category: Pathology Authors: Yue Sun Timothy D Weber James G Fujimoto Seymour Rosen Paul A VanderLaan Source Type: research

Key Learnings from 'Seniors of Canada': A Community Project Aimed to Disrupt Ageism
This article highlights insights gained since the inception of the project, including three key learnings: (1) Building bridges across academia and community, (2) Intergenerational connection and digital tools, and (3) The power of visual storytelling. We provide a practical overview of a successful knowledge mobilization/community outreach project and showcase the power of bridging academia and community for social change.PMID:38679950 | DOI:10.1017/S0714980824000151 (Source: Canadian Journal on Aging)
Source: Canadian Journal on Aging - April 29, 2024 Category: Geriatrics Authors: Stephanie Hatzifilalithis Rachel Weldrick Kelsey Harvey Source Type: research

Indonesia's healthcare landscape: embracing innovation in the new health regime
Curr Med Res Opin. 2024 Apr 29:1-8. doi: 10.1080/03007995.2024.2349732. Online ahead of print.ABSTRACTThe comment highlights the intricate health issues in Indonesia, emphasizing urban-rural gaps, healthcare financing challenges, and the government's dedication to Universal Health Coverage (UHC). The country's geographical layout amplifies the struggle of providing healthcare to rural areas, resulting in substantial health concerns like high tuberculosis rates and financial vulnerability for the impoverished. The concern raised underscores the paradox of low state healthcare spending despite high household expenditures, le...
Source: Current Medical Research and Opinion - April 29, 2024 Category: Research Authors: Ferry Fadzlul Rahman Source Type: research

Rapid examination of lung tissues by nonlinear microscopy
CONCLUSIONS: This study demonstrated that nonlinear microscopy readily replicates traditional H&E staining for both lung tumors and nonneoplastic pulmonary structures. Nonlinear microscopy provides many advantages over frozen section analysis and is an optical imaging platform that has the potential to augment rapid pathologic evaluation of resected tissues in the age of digital pathology.PMID:38682548 | DOI:10.1093/ajcp/aqae046 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Yue Sun Timothy D Weber James G Fujimoto Seymour Rosen Paul A VanderLaan Source Type: research