What Do Hospitalists Need to Know About Monkeypox?
What is monkeypox? Monkeypox is a rare infection caused by the monkeypox virus. Monkeypox virus belongs to the Orthopoxvirus genus in the family Poxviridae. The Orthopoxvirus genus also includes variola virus (which causes smallpox), vaccinia virus (used in the smallpox vaccine), and cowpox virus.1 It was first isolated in 1958 and identified as causing human disease in 1970. This pathogen was endemic in central and western African countries up until recently. Between 2018 to May 2022, about nine cases of monkeypox were confirmed in a few non-endemic countries.2
There are two strains of monkeypox:
West African monkeypox ...
Source: The Hospitalist - June 24, 2022 Category: Hospital Management Authors: Daniel Hickman Tags: Clinical Guidelines Diagnostic Emerging Infections Infectious Diseases Source Type: research
Generalized Pustular Psoriasis in Pregnancy: Current and Future Treatments
AbstractGeneralized pustular psoriasis (GPP) is a rare, severe neutrophilic skin disease characterized by sudden widespread eruption of sterile pustules with or without systemic symptoms. GPP may be life threatening in cases with severe complications such as cardiovascular failure, acute respiratory distress syndrome, and serious infections. Impetigo herpetiformis (IH) is a GPP that is induced and exacerbated by pregnancy and occurs most frequently during the last trimester. IH may result in poor or fatal neonatal outcomes, including placental insufficiency, fetal abnormalities, stillbirth, and early neonatal death. Most p...
Source: American Journal of Clinical Dermatology - June 15, 2022 Category: Dermatology Source Type: research
A bullous rash
A 3-year-old boy presented with a 5-day history of bullous skin lesions localised mainly in the upper and lower limbs and in the genital region (figure 1). Lesions were not pruritic nor painful and showed a central crust. There was no family history of skin disorders or autoimmune diseases. The child never had fever and his physical examination was otherwise unremarkable.
Figure 1Bullous skin lesions forming around a central crust, localised in the upper and lower limbs.
Questions
What is the most likely diagnosis based on this clinical presentation?
Bullous impetigo.
Bullous pemphigoid.
Linear IgA bullous der...
Source: Archives of Disease in Childhood - Education and Practice - May 19, 2022 Category: Pediatrics Authors: Migliarino, V., Di Mascio, A., Berti, I., Taddio, A., Barbi, E. Tags: Epilogue Source Type: research
Case Report and Literature Review of Impetigo-Like Tinea Faciei
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - May 12, 2022 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
First-Trimester Impetigo Herpetiformis Leads to Stillbirth: A Case Report
ConclusionsChloroquine has potential to lead to PPP in the first trimester of pregnancy. Further studies are warranted to investigate the etiology and treatment of PPP to facilitate early recognition and optimal management of this relatively rare dermatosis in pregnancy. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - May 2, 2022 Category: Dermatology Source Type: research
Bullous Impetigo Following an Abrasion in a 17-Year-Old Female
Teledermatology is a term to describe the provision of dermatologic medical services through telecommunication technology. This is a teledermatology case of bullous impetigo. (Source: JDNA: Journal of the Dermatology Nurses Association)
Source: JDNA: Journal of the Dermatology Nurses Association - May 1, 2022 Category: Dermatology Tags: DEPARTMENTS: Teledermatology Viewpoint Source Type: research
Missing Piece Study protocol: prospective surveillance to determine the epidemiology of group A streptococcal pharyngitis and impetigo in remote Western Australia
Introduction
Group A β-haemolytic Streptococcus (GAS), a Gram-positive bacterium, causes skin, mucosal and systemic infections. Repeated GAS infections can lead to autoimmune diseases acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Aboriginal and Torres Strait Islander peoples in Australia have the highest rates of ARF and RHD in the world. Despite this, the contemporaneous prevalence and incidence of GAS pharyngitis and impetigo in remote Australia remains unknown. To address this, we have designed a prospective surveillance study of GAS pharyngitis and impetigo to collect coincident contemporary evide...
Source: BMJ Open - April 6, 2022 Category: General Medicine Authors: Barth, D. D., Mullane, M. J., Sampson, C., Chou, C., Pickering, J., Nicol, M. P., Davies, M. R., Carapetis, J., Bowen, A. C. Tags: Open access, Epidemiology Source Type: research
Proteome based mapping and reverse vaccinology techniques to contrive multi-epitope based subunit vaccine (MEBSV) against Streptococcus pyogenes
Infect Genet Evol. 2022 Feb 26:105259. doi: 10.1016/j.meegid.2022.105259. Online ahead of print.ABSTRACTStreptococcus pyogenes is a root cause of human infection like pharyngitis, tonsillitis, scarlet fever, impetigo, and respiratory tract infections. About 11 million individuals in the US suffer from pharyngitis every year. Unfortunately, no vaccine against S. pyogenes is available yet. The purpose of this study is to create a multiepitope-based subunit vaccine (MEBSV) targeting S. pyogenes top four highly antigenic proteins by using a combination of immunological techniques and molecular docking to tackle term group A st...
Source: Infection, Genetics and Evolution - March 1, 2022 Category: Genetics & Stem Cells Authors: Sidra Aslam Usman Ali Ashfaq Tuba Zia Nosheen Aslam Faris Alrumaihi Farah Shahid Fatima Noor Muhammad Qasim Source Type: research
Proteome based mapping and reverse vaccinology techniques to contrive multi-epitope based subunit vaccine (MEBSV) against Streptococcus pyogenes
Infect Genet Evol. 2022 Feb 26:105259. doi: 10.1016/j.meegid.2022.105259. Online ahead of print.ABSTRACTStreptococcus pyogenes is a root cause of human infection like pharyngitis, tonsillitis, scarlet fever, impetigo, and respiratory tract infections. About 11 million individuals in the US suffer from pharyngitis every year. Unfortunately, no vaccine against S. pyogenes is available yet. The purpose of this study is to create a multiepitope-based subunit vaccine (MEBSV) targeting S. pyogenes top four highly antigenic proteins by using a combination of immunological techniques and molecular docking to tackle term group A st...
Source: Infection, Genetics and Evolution - March 1, 2022 Category: Genetics & Stem Cells Authors: Sidra Aslam Usman Ali Ashfaq Tuba Zia Nosheen Aslam Faris Alrumaihi Farah Shahid Fatima Noor Muhammad Qasim Source Type: research
Prevalence of Infectious Diseases Among 6078 Individuals With Down Syndrome in the United States
J Patient Cent Res Rev. 2022 Jan 17;9(1):64-69. doi: 10.17294/2330-0698.1876. eCollection 2022 Winter.ABSTRACTA recent disease prevalence study of the largest documented Down syndrome (DS) cohort in the United States strongly suggested significant disparity in general infectious disease conditions among individuals with DS versus those without DS. In this follow-up retrospective analysis, we explored these differences in greater detail by calculating prevalence of 52 infectious diseases, across 28 years of data among 6078 individuals with DS and 30,326 age- and sex-matched controls, abstracted from electronic medical recor...
Source: Herpes - February 3, 2022 Category: Infectious Diseases Authors: Veronica Fitzpatrick Anne Rivelli Sagar Chaudhari Laura Chicoine Gengjie Jia Andrey Rzhetsky Brian Chicoine Source Type: research
Prevalence of Infectious Diseases Among 6078 Individuals With Down Syndrome in the United States
J Patient Cent Res Rev. 2022 Jan 17;9(1):64-69. doi: 10.17294/2330-0698.1876. eCollection 2022 Winter.ABSTRACTA recent disease prevalence study of the largest documented Down syndrome (DS) cohort in the United States strongly suggested significant disparity in general infectious disease conditions among individuals with DS versus those without DS. In this follow-up retrospective analysis, we explored these differences in greater detail by calculating prevalence of 52 infectious diseases, across 28 years of data among 6078 individuals with DS and 30,326 age- and sex-matched controls, abstracted from electronic medical recor...
Source: Herpes - February 3, 2022 Category: Infectious Diseases Authors: Veronica Fitzpatrick Anne Rivelli Sagar Chaudhari Laura Chicoine Gengjie Jia Andrey Rzhetsky Brian Chicoine Source Type: research
CDLQI-based assessment of skin disorders among children: A study from Northern India
Conclusion: Our study has shown that skin diseases, irrespective of the type, adversely impair the quality of life of the child and in turn the family, therefore, calls for an enhanced level of compassion and care. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - January 28, 2022 Category: Dermatology Authors: Sheena Goyal Naheed Sajid Sudhir U K. Nayak Sajid Husain Source Type: research
Comprehensive Assessment of Skin Disorders in Patients with Common Variable Immunodeficiency (CVID)
ConclusionThis rate of skin disorders in our cohort demonstrating these manifestations could be significant in CVID patients, and they are not rare. Low data of skin complications in CVID patients could be attributed to insufficient attention of physicians and also might alert dermatologists to perform immunological investigations in children with certain skin manifestations. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - January 27, 2022 Category: Allergy & Immunology Source Type: research
