Optimizing Antibiotic Treatment of Skin Infections in Pediatric Emergency and Urgent Care Centers
CONCLUSIONSWe improved optimal choice and reduced duration of antibiotic treatment of outpatient SSTIs. MOC participation was associated with greater improvement and was sustained after the intervention period. (Source: PEDIATRICS)
Source: PEDIATRICS - September 8, 2022 Category: Pediatrics Source Type: research
33635 Recalcitrant bullous rash presenting in a pediatric patient, ultimately responsive to dupilimab
A 17-year-old female reported a pruritic blister on the left breast 2 months prior to presentation. Within a month she noticed vesicles on the inner legs. Her primary care physician prescribed doxycycline for possible impetigo. The lesions continued to spread so she was referred to dermatology. On examination, there were multiple tense bullae symmetrically distributed on the face, trunk, and extremities. There was a single erosion of the hard palate and excoriated vesicles of the labia majora. A biopsy showed a subepidermal split with a predominance of neutrophils and eosinophils. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 1, 2022 Category: Dermatology Authors: Kimberly Shao Source Type: research
Skin findings of impetigo neonatorum and staphylococcal scalded skin syndrome
A 4-week-old male infant presented with 5 days of honey-crusted facial rash (Figure, A). He was admitted to a local children's hospital to initiate therapy. Initial intravenous line placement attempts triggered Nikolsky sign, with skin exfoliation at sites of lateral pressure on the patient's feet (Figure, B). Over the next 2 days, skin desquamation progressed over the legs and torso. A facial swab grew abundant methicillin-susceptible Staphylococcus aureus (MSSA), supporting the diagnosis of local impetigo neonatorum with disseminated, toxin-mediated Staphylococcal scalded skin syndrome (SSSS). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - August 14, 2022 Category: Pediatrics Authors: Elizabeth A. Daniels, David A. Rosen Tags: Rediscovering the Physical Exam Source Type: research
Skin Findings of Impetigo Neonatorum and Staphylococcal Scalded Skin Syndrome
A 4-week-old male infant presented with 5 days of honey-crusted facial rash (Figure A). He was admitted to a local children ’s hospital to initiate therapy. Initial intravenous line placement attempts triggered Nikolskys sign, with skin exfoliation at sites of lateral pressure on the patient’s feet (Figure B). Over the next two days, skin desquamation progressed over the legs and torso. A facial swab grew abundant me thicillin-susceptible Staphylococcus aureus (MSSA), supporting the diagnosis of local impetigo neonatorum with disseminated, toxin-mediated Staphylococcal scalded skin syndrome (SSSS). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - August 14, 2022 Category: Pediatrics Authors: Elizabeth A. Daniels, David A. Rosen Tags: Rediscovering the Physical Exam Source Type: research
The burden of bacterial skin infection, scabies and atopic dermatitis among urban-living Indigenous children in high-income countries: a protocol for a systematic review
This study will identify and evaluate epidemiological data on bacterial skin infection, scabies and atopic dermatitis in urban-living Indigenous children in high-income countries. Where available, the clinical features, risk factors, comorbidities and complications of these common childhood skin disorders will be described. The evidence will highlight the burden of disease in this population, to contribute to global burden of disease estimates and identify gaps in the current literature to provide direction for future research.Systematic review registrationPROSPERO CRD42021277288 (Source: Systematic Reviews)
Source: Systematic Reviews - August 9, 2022 Category: International Medicine & Public Health Source Type: research
In vitro antibacterial activity of Western Australian honeys, and manuka honey, against bacteria implicated in impetigo
In this study we evaluated the potential for honey as an alternative treatment for impetigo. A broth microdilution assay in 96-well microtitre trays was used to determine the minimum inhibitory concentrations (MICs) of six monofloral honeys (jarrah, marri, red bell, banksia, wandoo, and manuka), a multifloral honey and artificial honey against S. aureus (n = 10), S. pyogenes (n = 10), and coagulase-negative staphylococci (CoNS) (n = 10). The optical density (OD) of all microtitre tray wells was also determined before and after assay incubation to analyse whether sub-MIC growth inhibition occurred. Jarrah, marri, red bell, ...
Source: Complementary Therapies in Clinical Practice - July 22, 2022 Category: Complementary Medicine Authors: Ayushi Chhawchharia Robbie R Haines Kathryn J Green Timothy C Barnett Asha C Bowen Katherine A Hammer Source Type: research
